Nerve lesioning with direct current.

abstract：OBJECTIVE:Current brain-computer interface (BCI) studies demonstrate the potential to decode neural signals obtained from structured and trial-based tasks to drive actuators with high performance within the context of these tasks. Ideally, to maximize utility, such systems will be applied to a wide range of behavioral ...

journal_title：Journal of neural engineering

authors： Alasfour A,Gabriel P,Jiang X,Shamie I,Melloni L,Thesen T,Dugan P,Friedman D,Doyle W,Devinsky O,Gonda D,Sattar S,Wang S,Halgren E,Gilja V

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Wireless control and power harvesting systems that operate injectable, cellular-scale optoelectronic components provide important demonstrated capabilities in neuromodulatory techniques such as optogenetics. Here, we report a radio frequency (RF) control/harvesting device that offers dramatically reduced size...

journal_title：Journal of neural engineering

authors： Park SI,Shin G,Banks A,McCall JG,Siuda ER,Schmidt MJ,Chung HU,Noh KN,Mun JG,Rhodes J,Bruchas MR,Rogers JA

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Brain-computer interface (BCI) technology aims to provide individuals with paralysis a means to restore function. Electrocorticography (ECoG) uses disc electrodes placed on either the surface of the dura or the cortex to record field potential activity. ECoG has been proposed as a viable neural recording moda...

journal_title：Journal of neural engineering

authors： Degenhart AD,Hiremath SV,Yang Y,Foldes S,Collinger JL,Boninger M,Tyler-Kabara EC,Wang W

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Resting state functional connectivity (RSFC) allows the study of functional organization in normal and diseased brain by measuring the spontaneous brain activity generated under resting conditions. Intrinsic optical signal imaging (IOSI) based on multiple illumination wavelengths has been used successfully to...

journal_title：Journal of neural engineering

authors： Kura S,Xie H,Fu B,Ayata C,Boas DA,Sakadžić S

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Among electrophysiological signals, local field potentials (LFPs) are extensively used to study brain activity, either in vivo or in vitro. LFPs are recorded with extracellular electrodes implanted in brain tissue. They reflect intermingled excitatory and inhibitory processes in neuronal assemblies. In cortic...

journal_title：Journal of neural engineering

authors： Yochum M,Modolo J,Mogul DJ,Benquet P,Wendling F

更新日期：2019-04-01 00:00:00

abstract：:Brain-computer interface (BCI) systems do not work for all users. This article introduces a novel combination of tasks that could inspire BCI systems that are more accurate than conventional BCIs, especially for users who cannot attain accuracy adequate for effective communication. Subjects performed tasks typically u...

journal_title：Journal of neural engineering

authors： Allison BZ,Brunner C,Kaiser V,Müller-Putz GR,Neuper C,Pfurtscheller G

更新日期：2010-04-01 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthalamic nucleus with periodic, high-frequency pulse trains is an increasingly standard therapy for advanced Parkinson's disease. Here, we propose that a closed-loop global optimization algorithm may identify novel DBS waveforms that could be more effective than their high-freque...

journal_title：Journal of neural engineering

authors： Feng XJ,Greenwald B,Rabitz H,Shea-Brown E,Kosut R

更新日期：2007-06-01 00:00:00

abstract：:Automatic spike sorting is a prerequisite for neuroscience research on multichannel extracellular recordings of neuronal activity. A novel spike sorting framework, combining efficient feature extraction and an unsupervised clustering method, is described here. Wavelet transform (WT) is adopted to extract features from...

journal_title：Journal of neural engineering

authors： Lai HY,Chen YY,Lin SH,Lo YC,Tsang S,Chen SY,Zhao WT,Chao WH,Chang YC,Wu R,Shih YY,Tsai ST,Jaw FS

更新日期：2011-06-01 00:00:00

abstract：:The blood oxygenation level dependent (BOLD) contrast has been commonly used to detect fMRI signal. The majority of the BOLD signals are believed to arise from the venous and capillary networks. However, only those from the capillaries are spatially close to the neuronal activities, while the signals from large veins ...

journal_title：Journal of neural engineering

authors： Song AW,Gangstead SL

更新日期：2004-03-01 00:00:00

abstract：:After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...

journal_title：Journal of neural engineering

authors： Ouyang L,Shaw CL,Kuo CC,Griffin AL,Martin DC

更新日期：2014-04-01 00:00:00

abstract：:This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...

journal_title：Journal of neural engineering

authors： Dominguez LG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Haptic perception of a prosthetic limb or hand is a crucial, but often unmet, need which impacts the utility of the prostheses. In this study, we seek to evaluate the feasibility of a non-invasive transcutaneous nerve stimulation method in generating haptic feedback in a transradial amputee subject as well as...

journal_title：Journal of neural engineering

authors： Shin H,Watkins Z,Huang HH,Zhu Y,Hu X

更新日期：2018-08-01 00:00:00

abstract：:We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...

journal_title：Journal of neural engineering

authors： Zviagintsev A,Perelman Y,Ginosar R

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:The reliable estimation of parameters such as mean or covariance matrix from noisy and high-dimensional observations is a prerequisite for successful application of signal processing and machine learning algorithms in brain-computer interfacing (BCI). This challenging task becomes significantly more difficult...

journal_title：Journal of neural engineering

authors： Samek W,Nakajima S,Kawanabe M,Müller KR

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Low-intensity focused ultrasound stimulation (LIFUS) emerges as an attracting technology for noninvasive modulation of neural circuits, yet the underlying action mechanisms remain unclear. The neuronal intramembrane cavitation excitation (NICE) model suggests that LIFUS excites neurons through a complex inter...

journal_title：Journal of neural engineering

authors： Lemaire T,Neufeld E,Kuster N,Micera S

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. How...

journal_title：Journal of neural engineering

authors： Valsky D,Blackwell KT,Tamir I,Eitan R,Bergman H,Israel Z

更新日期：2020-01-06 00:00:00

abstract：:All of the human prosthetic visual systems implanted so far have been achromatic. Schmidt et al. (1996) reported that at low stimulation intensities their subject reported that phosphenes usually had a specific hue, but when the stimulus intensity was increased, they desaturated to white. We speculate here that previo...

journal_title：Journal of neural engineering

authors： Towle V,Pham T,McCaffrey M,Allen D,Troyk PR

更新日期：2020-12-18 00:00:00

abstract：:To study cell-field dynamics, physiologists simultaneously record local field potentials and the activity of individual cells from animals performing cognitive tasks, during various brain states or under pathological conditions. However, apart from spike shape and spike timing analyses, few studies have focused on elu...

journal_title：Journal of neural engineering

authors： Cotic M,Chiu AW,Jahromi SS,Carlen PL,Bardakjian BL

更新日期：2011-08-01 00:00:00

abstract：:Retinal implants have proven their ability to restore visual sensation to people with degenerative retinopathy, characterized by photoreceptor cell death and the retina's inability to sense light. Retinal bionics operate by electrically stimulating the surviving neurons in the retina, thus triggering the transfer of v...

journal_title：Journal of neural engineering

authors： Bareket L,Barriga-Rivera A,Zapf MP,Lovell NH,Suaning GJ

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Implantable brain-computer interface (BCI) research promises improvements in human health and enhancements in quality of life. Informed consent of subjects is a central tenet of this research. Rapid advances in neuroscience, and the intimate connection between functioning of the brain and conceptions of the s...

journal_title：Journal of neural engineering

authors： Klein E,Ojemann J

更新日期：2016-08-01 00:00:00

abstract：:A motor imagery based brain-computer interface (BCI) provides a non-muscular communication channel that enables people with paralysis to control external devices using their motor imagination. Reducing the number of electrodes is critical to improving the portability and practicability of the BCI system. A novel metho...

journal_title：Journal of neural engineering

authors： Lou B,Hong B,Gao X,Gao S

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well-understood. In particular, the connections between brain regions remain unclear. Using the emo...

journal_title：Journal of neural engineering

authors： Guo Z,Wu X,Liu J,Yao L,Hu B

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:The Subthalamic Nucleus (STN) is the most selected target for the placement of the Deep Brain Stimulation (DBS) electrode to treat Parkinson's disease. Its identification is a delicate and challenging task which is based on the interpretation of the STN functional activity acquired through microelectrode reco...

journal_title：Journal of neural engineering

authors： Coelli S,Levi V,Del Vecchio Del Vecchio J,Mailland E,Rinaldo S,Eleopra R,Bianchi AM

更新日期：2020-11-17 00:00:00

abstract：OBJECTIVE:We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or above the dura mater. Theoretically, the subdural location combines ...

journal_title：Journal of neural engineering

authors： Capogrosso M,Gandar J,Greiner N,Moraud EM,Wenger N,Shkorbatova P,Musienko P,Minev I,Lacour S,Courtine G

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Electrical brain stimulation is recognized as a promising therapeutic approach for treating brain disorders such as epilepsy. However, the use of this technique is still largely empirical, since stimulation parameters and targets are chosen using a trial-and-error approach. Therefore, there is a pressing nee...

journal_title：Journal of neural engineering

authors： Arrais M,Modolo J,Mogul D,Wendling F

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVE:Recording of neural signals from intact peripheral nerves in patients with spinal cord injury or stroke survivors offers the possibility for the development of closed-loop sensorimotor prostheses. Nerve cuffs have been found to provide stable recordings from peripheral nerves for prolonged periods of time. Ho...

journal_title：Journal of neural engineering

authors： Silveira C,Brunton E,Spendiff S,Nazarpour K

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Haptic feedback is crucial when we manipulate objects. Information pertaining to an object's stiffness in particular can help facilitate fine motor control. In this study, we seek to determine whether objects of different stiffness levels can be recognized using haptic feedback provided by transcutaneous elec...

journal_title：Journal of neural engineering

authors： Vargas L,Shin H,Huang HH,Zhu Y,Hu X

更新日期：2019-12-05 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00