Advantages of soft subdural implants for the delivery of electrochemical neuromodulation therapies to the spinal cord.

abstract：OBJECTIVE:The rapidly developing paradigm of closed-loop neuroscience has extensively employed brain rhythms as the signal forming real-time neurofeedback, triggering brain stimulation, or governing stimulus selection. However, the efficacy of brain rhythm contingent paradigms suffers from significant delays related to...

journal_title：Journal of neural engineering

authors： Smetanin N,Belinskaya A,Lebedev M,Ossadtchi A

更新日期：2020-08-04 00:00:00

abstract：:We consider the problem of desynchronizing a network of synchronized, globally (all-to-all) coupled neurons using an input to a single neuron. This is done by applying the discrete time dynamic programming method to reduced phase models for neural populations. This technique numerically minimizes a certain cost functi...

journal_title：Journal of neural engineering

authors： Nabi A,Moehlis J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Despite their increasing use and public health importance, little is known about the consistency and variability of the quantitative features of baseline electroencephalography (EEG) measurements in healthy individuals and populations. This study aims to investigate population consistency of EEG features. AP...

journal_title：Journal of neural engineering

authors： Nahmias DO,Kontson KL,Soltysik DA,Civillico EF

更新日期：2019-11-12 00:00:00

abstract：:Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...

journal_title：Journal of neural engineering

authors： Stice P,Muthuswamy J

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：:We hypothesize that a visual prosthesis capable of evoking high-resolution visual perceptions can be produced using high-electrode-count arrays of penetrating microelectrodes implanted into the primary visual cortex of a blind human subject. To explore this hypothesis, and as a prelude to human psychophysical experime...

journal_title：Journal of neural engineering

authors： Torab K,Davis TS,Warren DJ,House PA,Normann RA,Greger B

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:Transcranial Doppler (TCD) was recently introduced as a new brain-computer interface (BCI) modality for detecting task-induced hemispheric lateralization. To date, single-trial discrimination between a lateralized mental activity and a rest state has been demonstrated with long (45 s) activation time periods...

journal_title：Journal of neural engineering

authors： Aleem I,Chau T

更新日期：2013-02-01 00:00:00

abstract：:In this paper, we investigate the influence of hypercapnia on the dynamics of the phrenic neurogram in the piglet in two different age groups: 3-7 days (n = 11) and 10-16 days (n = 9). The phrenic neurogram was recorded from 17 piglets (3-16 days old) during control (40% O(2) with 3-5% end-tidal CO(2)), mild hypercapn...

journal_title：Journal of neural engineering

authors： Akay M

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Electrical status epilepticus during sleep (ESES), as electroencephalographic disturbances, is characterized by strong activation of epileptiform activity in the electroencephalogram during sleep. Quantitative descriptors of such epileptiform activity can support the diagnose and the prognosis of children wit...

journal_title：Journal of neural engineering

authors： Zhao X,Wang X,Chen C,Fan J,Yu X,Wang Z,Akbarzadeh S,Li Q,Zhou S,Chen W

更新日期：2020-08-11 00:00:00

abstract：OBJECTIVE:To determine whether the estimated fraction and degree of distribution of visual responsive neurons in human intracranial microwire recordings depends upon the spike sorting method used. APPROACH:A large dataset of human intracranial microwire recordings from four brain areas was sorted into single unit acti...

journal_title：Journal of neural engineering

authors： Steinmetz PN

更新日期：2020-04-09 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthalamic nucleus with periodic, high-frequency pulse trains is an increasingly standard therapy for advanced Parkinson's disease. Here, we propose that a closed-loop global optimization algorithm may identify novel DBS waveforms that could be more effective than their high-freque...

journal_title：Journal of neural engineering

authors： Feng XJ,Greenwald B,Rabitz H,Shea-Brown E,Kosut R

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...

journal_title：Journal of neural engineering

authors： Cai C,Twyford P,Fried S

更新日期：2013-06-01 00:00:00

abstract：:In a recent paper by Bradberry, Gentili and Contreras-Vidal published in Journal of Neural Engineering (2011, 8 036010), an interesting method for the control of a two-dimensional mouse cursor was proposed, which apparently attained excellent control and good speed with relatively simple techniques. We believe some of...

journal_title：Journal of neural engineering

authors： Poli R,Salvaris M

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Powered robotic prostheses create a need for natural-feeling user interfaces and robust control schemes. Here, we examined the ability of a nonlinear autoregressive model to continuously map the kinematics of a transtibial prosthesis and electromyographic (EMG) activity recorded within socket to the future es...

journal_title：Journal of neural engineering

authors： Farmer S,Silver-Thorn S,Voglewede P,Beardsley SA

更新日期：2014-10-01 00:00:00

abstract：:The extraction of distinctly separable features from electroencephalogram (EEG) is one of the main challenges in designing a brain-computer interface (BCI). Existing feature extraction techniques for a BCI are mostly developed based on traditional signal processing techniques assuming that the signal is Gaussian and h...

journal_title：Journal of neural engineering

authors： Shahid S,Prasad G

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Somatic symptom disorder (SSD) is a reflection of medically unexplained physical symptoms that lead to distress and impairment in social and occupational functioning. SSD is phenomenologically diagnosed and its neurobiology remains unsolved. APPROACH:In this study, we performed hyper-parameter optimized clas...

journal_title：Journal of neural engineering

authors： Eken A,Çolak B,Bal NB,Kuşman A,Kızılpınar SÇ,Akaslan DS,Baskak B

更新日期：2019-12-16 00:00:00

abstract：OBJECTIVE:There has recently been an increasing interest in local field potential (LFP) for brain-machine interface (BMI) applications due to its desirable properties (signal stability and low bandwidth). LFP is typically recorded with respect to a single unipolar reference which is susceptible to common noise. Several...

journal_title：Journal of neural engineering

authors： Ahmadi N,Constandinou T,Bouganis CS

更新日期：2020-11-26 00:00:00

abstract：:Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...

journal_title：Journal of neural engineering

authors： Parikh H,Marzullo TC,Kipke DR

更新日期：2009-04-01 00:00:00

abstract：:With the advent of new designs of visual prostheses for the blind, FDA is faced with developing guidance for evaluating their engineering, safety and patient performance. Visual prostheses are considered significant risk medical devices, and their use in human clinical trials must be approved by FDA under an investiga...

journal_title：Journal of neural engineering

authors： Cohen ED

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Intracortical brain-machine interfaces (iBMIs) aim to restore efficient communication and movement ability for paralyzed patients. However, frequent recalibration is required for consistency and reliability, and every recalibration will require relatively large most current sample set. The aim in this study i...

journal_title：Journal of neural engineering

authors： Zhang P,Ma X,Chen L,Zhou J,Wang C,Li W,He J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well-understood. In particular, the connections between brain regions remain unclear. Using the emo...

journal_title：Journal of neural engineering

authors： Guo Z,Wu X,Liu J,Yao L,Hu B

更新日期：2018-10-01 00:00:00

abstract：:In this paper, we propose a simple and straightforward algorithm for neural spike sorting. The algorithm is based on the observation that the distribution of a neural signal largely deviates from the uniform distribution and is rather unimodal. The detected spikes to be sorted are first processed with some feature ext...

journal_title：Journal of neural engineering

authors： Tiganj Z,Mboup M

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...

journal_title：Journal of neural engineering

authors： Haufe S,Kim JW,Kim IH,Sonnleitner A,Schrauf M,Curio G,Blankertz B

更新日期：2014-10-01 00:00:00

abstract：:Deep brain stimulation (DBS) has emerged as an effective treatment for movement disorders; however, the fundamental mechanisms by which DBS works are not well understood. Computational models of DBS can provide insights into these fundamental mechanisms and typically require two steps: calculation of the electrical po...

journal_title：Journal of neural engineering

authors： Zhang TC,Grill WM

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Sleep spindles in the electroencephalogram (EEG) are significant in sleep analysis related to cognitive functions and neurological diseases, and thus are of great clinical interests. An automatic sleep spindle detection algorithm could help decrease the workload of visual inspection by sleep clinicians. APPR...

journal_title：Journal of neural engineering

authors： Jiang D,Ma Y,Wang Y

更新日期：2020-12-16 00:00:00

abstract：:Functional electrical stimulation (FES) involves artificial activation of muscles with surface or implanted electrodes to restore motor function in paralyzed individuals. Currently, FES-based prostheses produce only a limited range of movements due to the difficulty associated with identifying patterns of muscle activ...

journal_title：Journal of neural engineering

authors： Johnson LA,Fuglevand AJ

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00

abstract：:In this work the application of different machine learning techniques for classification of mental tasks from electroencephalograph (EEG) signals is investigated. The main application for this research is the improvement of brain computer interface (BCI) systems. For this purpose, Bayesian graphical network, neural ne...

journal_title：Journal of neural engineering

authors： Rezaei S,Tavakolian K,Nasrabadi AM,Setarehdan SK

更新日期：2006-06-01 00:00:00