Design of optimal multi-site brain stimulation protocols via neuro-inspired epilepsy models for abatement of interictal discharges.

abstract：OBJECTIVE:Many physical models of biological processes including neural systems are characterized by parametric nonlinear dynamical relations between driving inputs, internal states, and measured outputs of the process. Fitting such models using experimental data (data assimilation) is a challenging task since the phys...

journal_title：Journal of neural engineering

authors： Madi MK,Karameh FN

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:The various parameters that define a hand movement such as its trajectory, speed, etc, are encoded in distinct brain activities. Decoding this information from neurophysiological recordings is a less explored area of brain-computer interface (BCI) research. Applying non-invasive recordings such as electroence...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:In a previous study we demonstrated continuous translation, orientation and one-dimensional grasping control of a prosthetic limb (seven degrees of freedom) by a human subject with tetraplegia using a brain-machine interface (BMI). The current study, in the same subject, immediately followed the previous work...

journal_title：Journal of neural engineering

authors： Wodlinger B,Downey JE,Tyler-Kabara EC,Schwartz AB,Boninger ML,Collinger JL

更新日期：2015-02-01 00:00:00

abstract：:Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...

journal_title：Journal of neural engineering

authors： Parikh H,Marzullo TC,Kipke DR

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Multimodal neuroimaging approaches are beneficial to discover brain functionalities at high spatial and temporal resolution. In our work, a novel material composition of a microECoG device relying on Parylene HT and indium-tin-oxide (ITO) is presented, which facilitates two-photon imaging of Ca2+ signals and ...

journal_title：Journal of neural engineering

authors： Zátonyi A,Madarász M,Szabó Á,Lőrincz T,Hodován R,Rózsa B,Fekete Z

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. How...

journal_title：Journal of neural engineering

authors： Valsky D,Blackwell KT,Tamir I,Eitan R,Bergman H,Israel Z

更新日期：2020-01-06 00:00:00

abstract：OBJECTIVE:There has recently been an increasing interest in local field potential (LFP) for brain-machine interface (BMI) applications due to its desirable properties (signal stability and low bandwidth). LFP is typically recorded with respect to a single unipolar reference which is susceptible to common noise. Several...

journal_title：Journal of neural engineering

authors： Ahmadi N,Constandinou T,Bouganis CS

更新日期：2020-11-26 00:00:00

abstract：:In this paper we propose a dual stream neural network (DSNN) for classifying arbitrary collections of functional neuroimaging signals for the purpose of brain computer interfaces (BCIs). In the DSNN the first stream is an end-to-end classifier taking raw time-dependent signals as input and generating feature identific...

journal_title：Journal of neural engineering

authors： Kuang D,Michoski C

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVE:Over the past two decades retinal prostheses have made major strides in restoring functional vision to patients blinded by diseases such as retinitis pigmentosa. Presently, implants use single pulses to activate the retina. Though this stimulation paradigm has proved beneficial to patients, an unresolved prob...

journal_title：Journal of neural engineering

authors： Sekhar S,Jalligampala A,Zrenner E,Rathbun DL

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the estimated fraction and degree of distribution of visual responsive neurons in human intracranial microwire recordings depends upon the spike sorting method used. APPROACH:A large dataset of human intracranial microwire recordings from four brain areas was sorted into single unit acti...

journal_title：Journal of neural engineering

authors： Steinmetz PN

更新日期：2020-04-09 00:00:00

abstract：OBJECTIVE:The past two decades have seen dramatic progress in our ability to model brain signals recorded by electroencephalography, functional near-infrared spectroscopy, etc., and to derive real-time estimates of user cognitive state, response, or intent for a variety of purposes: to restore communication by the seve...

journal_title：Journal of neural engineering

authors： Kothe CA,Makeig S

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The Subthalamic Nucleus (STN) is the most selected target for the placement of the Deep Brain Stimulation (DBS) electrode to treat Parkinson's disease. Its identification is a delicate and challenging task which is based on the interpretation of the STN functional activity acquired through microelectrode reco...

journal_title：Journal of neural engineering

authors： Coelli S,Levi V,Del Vecchio Del Vecchio J,Mailland E,Rinaldo S,Eleopra R,Bianchi AM

更新日期：2020-11-17 00:00:00

abstract：:The aim of this study was to assess the accuracy of the convolution kernel compensation (CKC) method in decomposing high-density surface EMG (HDsEMG) signals from the pennate biceps femoris long-head muscle. Although the CKC method has already been thoroughly assessed in parallel-fibered muscles, there are several fac...

journal_title：Journal of neural engineering

authors： Marateb HR,McGill KC,Holobar A,Lateva ZC,Mansourian M,Merletti R

更新日期：2011-12-01 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：:Electrical stimulation of peripheral nerve activates large-diameter fibers before small ones. A physiological recruitment order, from small to large-diameter axons, is desirable in many applications. Previous studies using computer simulations showed that selective activation of small fibers could be achieved by resha...

journal_title：Journal of neural engineering

authors： Lertmanorat Z,Durand DM

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Most brain-computer interfaces (BCIs) based on functional near-infrared spectroscopy (fNIRS) require that users perform mental tasks such as motor imagery, mental arithmetic, or music imagery to convey a message or to answer simple yes or no questions. These cognitive tasks usually have no direct association ...

journal_title：Journal of neural engineering

authors： Rezazadeh Sereshkeh A,Yousefi R,Wong AT,Chau T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought to address this gap by evaluating vagal anatomy in the pig, whose ...

journal_title：Journal of neural engineering

authors： Settell ML,Pelot NA,Knudsen BE,Dingle AM,McConico AL,Nicolai EN,Trevathan JK,Ezzell JA,Ross EK,Gustafson KJ,Shoffstall AJ,Williams JC,Zeng W,Poore SO,Populin LC,Suminski AJ,Grill WM,Ludwig KA

更新日期：2020-04-09 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCI) are becoming important tools for assistive technology, particularly through the use of motor imagery (MI) for aiding task completion. However, most existing methods of MI classification have been applied in a trial-wise fashion, with window sizes of approximately 2 s or more. A...

journal_title：Journal of neural engineering

authors： Freer D,Yang GZ

更新日期：2020-01-31 00:00:00

abstract：:Neural activity can be modulated by applying a polarizing low-frequency (<100 Hz) electric field (PLEF). Unlike conventional pulsed stimulation, PLEF stimulation has a graded, modulatory effect on neuronal excitability, and permits the simultaneous recording of neuronal activity during stimulation suitable for continu...

journal_title：Journal of neural engineering

authors： Sunderam S,Chernyy N,Peixoto N,Mason JP,Weinstein SL,Schiff SJ,Gluckman BJ

更新日期：2009-08-01 00:00:00

abstract：:Implantable electrode arrays capable of recording and stimulating neural activity with high spatial and temporal resolution will provide a foundation for future brain computer interface technology. Currently, their clinical impact has been curtailed by a general lack of functional stability, which can be attributed to...

journal_title：Journal of neural engineering

authors： Retterer ST,Smith KL,Bjornsson CS,Turner JN,Isaacson MS,Shain W

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:A primary control signal in brain-computer interfaces (BCIs) have been cortical signals related to movement. However, in cases where natural motor function remains, BCI control signals may interfere with other possibly simultaneous activity for useful ongoing movement. We sought to determine if the brain coul...

journal_title：Journal of neural engineering

authors： Bashford L,Wu J,Sarma D,Collins K,Rao RPN,Ojemann JG,Mehring C

更新日期：2018-12-01 00:00:00

abstract：:One of the most important stages in a brain-computer interface (BCI) system is that of extracting features that can reliably discriminate data recorded during different user states. A popular technique used for feature extraction in BCIs is the common spatial patterns (CSP) method, which provides a set of spatial filt...

journal_title：Journal of neural engineering

authors： Falzon O,Camilleri KP,Muscat J

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the benefit of integrating thermal imaging into an artificial vision therapy system, the Argus II retinal prosthesis, in simplifying a complex scene and improving mobility performance in the presence of other persons. APPROACH:Four Argus II retinal implant users were evaluated on two tasks: to lo...

journal_title：Journal of neural engineering

authors： He Y,Sun SY,Roy A,Caspi A,Montezuma SR

更新日期：2020-08-04 00:00:00

abstract：:In this work we address the use of realtime cortical recordings for the generation of coherent, reliable and robust motor activity in spinal-lesioned animals through selective intraspinal microstimulation (ISMS). The spinal cord of adult rats was hemisectioned and groups of multielectrodes were implanted in both the c...

journal_title：Journal of neural engineering

authors： Panetsos F,Sanchez-Jimenez A,Torets C,Largo C,Micera S

更新日期：2011-08-01 00:00:00

abstract：:Some issues in neuroscience can be addressed by building robot models of biological sensorimotor systems. What we can conclude from building models or simulations, however, is determined by a number of factors in addition to the central hypothesis we intend to test. These include the way in which the hypothesis is rep...

journal_title：Journal of neural engineering

authors： Webb B

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:The majority of near-infrared spectroscopy (NIRS) brain-computer interface (BCI) studies have investigated binary classification problems. Limited work has considered differentiation of more than two mental states, or multi-class differentiation of higher-level cognitive tasks using measurements outside of th...

journal_title：Journal of neural engineering

authors： C Schudlo L,Chau T

更新日期：2015-12-01 00:00:00

abstract：:Corrosion is a prime concern for active implantable devices. In this paper we review the principles underlying the concepts of hermetic packages and encapsulation, used to protect implanted electronics, some of which remain widely overlooked. We discuss how technological advances have created a need to update the way ...

journal_title：Journal of neural engineering

authors： Vanhoestenberghe A,Donaldson N

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Current brain-computer interface (BCI) studies demonstrate the potential to decode neural signals obtained from structured and trial-based tasks to drive actuators with high performance within the context of these tasks. Ideally, to maximize utility, such systems will be applied to a wide range of behavioral ...

journal_title：Journal of neural engineering

authors： Alasfour A,Gabriel P,Jiang X,Shamie I,Melloni L,Thesen T,Dugan P,Friedman D,Doyle W,Devinsky O,Gonda D,Sattar S,Wang S,Halgren E,Gilja V

更新日期：2019-02-01 00:00:00