Toward the development of a color visual prosthesis.

abstract：OBJECTIVE:A signal-based metric for assessment of accuracy of motor unit (MU) identification from high-density surface electromyograms (EMG) is introduced. This metric, so-called pulse-to-noise-ratio (PNR), is computationally efficient, does not require any additional experimental costs and can be applied to every MU t...

journal_title：Journal of neural engineering

authors： Holobar A,Minetto MA,Farina D

更新日期：2014-02-01 00:00:00

abstract：:Brain-computer interface (BCI) systems allow people with severe motor disabilities to communicate and interact with the external world. The P300 potential is one of the most used control signals for EEG-based BCIs. Classic P300-based BCIs work in a synchronous mode; the synchronous control assumes that the user is con...

journal_title：Journal of neural engineering

authors： Aloise F,Schettini F,Aricò P,Leotta F,Salinari S,Mattia D,Babiloni F,Cincotti F

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Most recent steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems have used a single frequency for each target, so that a large number of targets require a large number of stimulus frequencies and therefore a wider frequency band. However, human beings show good SSVEP respo...

journal_title：Journal of neural engineering

authors： Chen X,Chen Z,Gao S,Gao X

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

journal_title：Journal of neural engineering

authors： Geronimo A,Simmons Z,Schiff SJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought to address this gap by evaluating vagal anatomy in the pig, whose ...

journal_title：Journal of neural engineering

authors： Settell ML,Pelot NA,Knudsen BE,Dingle AM,McConico AL,Nicolai EN,Trevathan JK,Ezzell JA,Ross EK,Gustafson KJ,Shoffstall AJ,Williams JC,Zeng W,Poore SO,Populin LC,Suminski AJ,Grill WM,Ludwig KA

更新日期：2020-04-09 00:00:00

abstract：:We present a micromachined 252-channel ECoG (electrocorticogram)-electrode array, which is made of a thin polyimide foil substrate enclosing sputtered platinum electrode sites and conductor paths. The array subtends an area of approximately 35 mm by 60 mm and is designed to cover large parts of a hemisphere of a macaq...

journal_title：Journal of neural engineering

authors： Rubehn B,Bosman C,Oostenveld R,Fries P,Stieglitz T

更新日期：2009-06-01 00:00:00

abstract：:Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...

journal_title：Journal of neural engineering

authors： Kofron CM,Fong VJ,Hoffman-Kim D

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:A primary control signal in brain-computer interfaces (BCIs) have been cortical signals related to movement. However, in cases where natural motor function remains, BCI control signals may interfere with other possibly simultaneous activity for useful ongoing movement. We sought to determine if the brain coul...

journal_title：Journal of neural engineering

authors： Bashford L,Wu J,Sarma D,Collins K,Rao RPN,Ojemann JG,Mehring C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well-understood. In particular, the connections between brain regions remain unclear. Using the emo...

journal_title：Journal of neural engineering

authors： Guo Z,Wu X,Liu J,Yao L,Hu B

更新日期：2018-10-01 00:00:00

abstract：:The aim of this paper is to use recent advances in the clinical understanding of the temporal evolution of seizure burden in neonates with hypoxic ischemic encephalopathy to improve the performance of automated detection algorithms. Probabilistic weights are designed from temporal locations of neonatal seizure events ...

journal_title：Journal of neural engineering

authors： Temko A,Stevenson N,Marnane W,Boylan G,Lightbody G

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Differential measurement of efferent and afferent peripheral nerve activity offers a promising means of improving the clinical utility of implantable neuroprostheses. The tripolar nerve cuff electrode has historically served as the gold standard for achieving high signal-to-noise ratios (SNRs) of the recordin...

journal_title：Journal of neural engineering

authors： Sabetian P,Popovic MR,Yoo PB

更新日期：2017-06-01 00:00:00

abstract：:Current treatment concepts for epilepsy are based on continuous drug delivery or electrical stimulation to prevent the occurrence of seizures, exposing the brain and body to a mostly unneeded risk of adverse effects. To address the infrequent occurrence and short duration of epileptic seizures, intelligent implantable...

journal_title：Journal of neural engineering

authors： Dümpelmann M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The clinical use of microsignals recorded over broad cortical regions is largely limited by the chronic reliability of the implanted interfaces. APPROACH:We evaluated the chronic reliability of novel 61-channel micro-electrocorticographic (µECoG) arrays in rats chronically implanted for over one year and usi...

journal_title：Journal of neural engineering

authors： Woods V,Trumpis M,Bent B,Palopoli-Trojani K,Chiang CH,Wang C,Yu C,Insanally MN,Froemke RC,Viventi J

更新日期：2018-12-01 00:00:00

abstract：:Brain-computer interfaces (BCIs) can use brain signals from the scalp (EEG), the cortical surface (ECoG), or within the cortex to restore movement control to people who are paralyzed. Like muscle-based skills, BCIs' use requires activity-dependent adaptations in the brain that maintain stable relationships between the...

journal_title：Journal of neural engineering

authors： McFarland DJ,Sarnacki WA,Wolpaw JR

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Rhythmic brain stimulation has emerged as a powerful tool to modulate cognition and to target pathological oscillations related to neurological and psychiatric disorders. However, we lack a systematic understanding of how periodic stimulation interacts with endogenous neural activity as a function of the brai...

journal_title：Journal of neural engineering

authors： Li G,Henriquez CS,Fröhlich F

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...

journal_title：Journal of neural engineering

authors： Bryan MJ,Martin SA,Cheung W,Rao RP

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:It is known that multi-site interleaved stimulation generates less muscle fatigue compared to single-site synchronous stimulation. However, in the limited number of studies in which intramuscular electrodes were used, the fatigue reduction associated with interleaved stimulation could not consistently be achi...

journal_title：Journal of neural engineering

authors： Eladly A,Del Valle J,Minguillon J,Mercadal B,Becerra-Fajardo L,Navarro X,Ivorra A

更新日期：2020-08-25 00:00:00

abstract：OBJECTIVE:Visual prostheses are designed to restore partial functional vision in patients with total vision loss. Retinal visual prostheses provide limited capabilities as a result of low resolution, limited field of view and poor dynamic range. Understanding the influence of these parameters in the perception results ...

journal_title：Journal of neural engineering

authors： Sanchez-Garcia M,Martinez-Cantin R,Bermudez-Cameo J,Guerrero JJ

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVE:We aim to increase the number of neural spikes that can be detected in a single channel extracellular neural recording. APPROACH:We propose a pre-emphasis method facilitating stochastic resonance (SR), where we introduce the band-pass-filtered noisy extracellular recording to an overdamped Brownian particle ...

journal_title：Journal of neural engineering

authors： Güngör CB,Töreyin H

更新日期：2020-09-18 00:00:00

abstract：OBJECTIVE:In biomagnetic signal processing, the theory of the signal subspace has been applied to removing interfering magnetic fields, and a representative algorithm is the signal space projection algorithm, in which the signal/interference subspace is defined in the spatial domain as the span of signal/interference-s...

journal_title：Journal of neural engineering

authors： Sekihara K,Nagarajan SS

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...

journal_title：Journal of neural engineering

authors： Werginz P,Rattay F

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Ultrasounds (US) use in neural engineering is so far mainly limited to ablation through high intensity focused ultrasound, but interesting preliminary results show that low intensity low frequency ultrasound could be used instead to modulate neural activity. However, the extent of this modulatory ability of U...

journal_title：Journal of neural engineering

authors： Meneghetti N,Dedola F,Gavryusev V,Sancataldo G,Turrini L,de Vito G,Tiso N,Vanzi F,Carpaneto J,Cutrone A,Pavone FS,Micera S,Mazzoni A

更新日期：2020-10-14 00:00:00

abstract：OBJECTIVE:Powered robotic prostheses create a need for natural-feeling user interfaces and robust control schemes. Here, we examined the ability of a nonlinear autoregressive model to continuously map the kinematics of a transtibial prosthesis and electromyographic (EMG) activity recorded within socket to the future es...

journal_title：Journal of neural engineering

authors： Farmer S,Silver-Thorn S,Voglewede P,Beardsley SA

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The generalization and robustness of an electroencephalogram (EEG)-based system are crucial requirements in actual practices. APPROACH:To reach these goals, we propose a new EEG representation that provides a more realistic view of brain functionality by applying multi-instance (MI) framework to consider the...

journal_title：Journal of neural engineering

authors： Sadatnejad K,Rahmati M,Rostami R,Kazemi R,Ghidary SS,Müller A,Alimardani F

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Activity-dependent stimulation (ADS) is designed to strengthen the connections between neuronal circuits and therefore may be a promising tool for promoting neurophysiological reorganization following a brain injury. To successfully perform this technique, two criteria must be met: (1) spikes in the extracell...

journal_title：Journal of neural engineering

authors： Murphy M,Buccelli S,Bornat Y,Bundy D,Nudo R,Guggenmos D,Chiappalone M

更新日期：2019-10-29 00:00:00

abstract：:Corrosion is a prime concern for active implantable devices. In this paper we review the principles underlying the concepts of hermetic packages and encapsulation, used to protect implanted electronics, some of which remain widely overlooked. We discuss how technological advances have created a need to update the way ...

journal_title：Journal of neural engineering

authors： Vanhoestenberghe A,Donaldson N

更新日期：2013-06-01 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：:The P300 speller is an example of a brain-computer interface that can restore functionality to victims of neuromuscular disorders. Although the most common application of this system has been communicating language, the properties and constraints of the linguistic domain have not to date been exploited when decoding b...

journal_title：Journal of neural engineering

authors： Speier W,Arnold C,Lu J,Taira RK,Pouratian N

更新日期：2012-02-01 00:00:00