Abstract:
:The P300 speller is an example of a brain-computer interface that can restore functionality to victims of neuromuscular disorders. Although the most common application of this system has been communicating language, the properties and constraints of the linguistic domain have not to date been exploited when decoding brain signals that pertain to language. We hypothesized that combining the standard stepwise linear discriminant analysis with a Naive Bayes classifier and a trigram language model would increase the speed and accuracy of typing with the P300 speller. With integration of natural language processing, we observed significant improvements in accuracy and 40-60% increases in bit rate for all six subjects in a pilot study. This study suggests that integrating information about the linguistic domain can significantly improve signal classification.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Speier W,Arnold C,Lu J,Taira RK,Pouratian Ndoi
10.1088/1741-2560/9/1/016004subject
Has Abstractpub_date
2012-02-01 00:00:00pages
016004issue
1eissn
1741-2560issn
1741-2552pii
S1741-2560(12)03058-8journal_volume
9pub_type
杂志文章abstract:OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. How...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab53ac
更新日期:2020-01-06 00:00:00
abstract:OBJECTIVE:When designing multiclass motor imagery-based brain-computer interface (MI-BCI), a so-called tangent space mapping (TSM) method utilizing the geometric structure of covariance matrices is an effective technique. This paper aims to introduce a method using TSM for finding accurate operational frequency bands r...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aac313
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:We implemented computational models of human and rat cortical neurons for simulating the neural response to cortical stimulation with electromagnetic fields. APPROACH:We adapted model neurons from the library of Blue Brain models to reflect biophysical and geometric properties of both adult rat and human cor...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aadbb1
更新日期:2018-12-01 00:00:00
abstract::After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/2/026005
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Research by Oby et al (2016) demonstrated that the optimal threshold for extracting information from visual and motor cortices may differ from the optimal threshold for identifying single neurons via spike sorting methods. The optimal threshold for extracting information from auditory cortex has yet to be ide...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab7c19
更新日期:2020-03-03 00:00:00
abstract::Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/6/2/026004
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:Wireless control and power harvesting systems that operate injectable, cellular-scale optoelectronic components provide important demonstrated capabilities in neuromodulatory techniques such as optogenetics. Here, we report a radio frequency (RF) control/harvesting device that offers dramatically reduced size...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/5/056002
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/4/046013
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Low-intensity transcranial ultrasound stimulation (TUS) is emerging as a non-invasive brain stimulation technique with superior spatial resolution and the ability to reach deep brain areas. Medical image-based computational modeling could be an important tool for individualized TUS dose control and targeting ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab98dc
更新日期:2020-07-13 00:00:00
abstract:OBJECTIVE:We have previously demonstrated a brain-machine interface neuroprosthetic system that provided continuous control of functional electrical stimulation (FES) and restoration of grasp in a primate model of spinal cord injury (SCI). Predicting intended EMG directly from cortical recordings provides a flexible hi...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/4/046009
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/2/026002
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or above the dura mater. Theoretically, the subdural location combines ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aaa87a
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:Visual prostheses are designed to restore partial functional vision in patients with total vision loss. Retinal visual prostheses provide limited capabilities as a result of low resolution, limited field of view and poor dynamic range. Understanding the influence of these parameters in the perception results ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abb9be
更新日期:2020-10-08 00:00:00
abstract:OBJECTIVE:Rhythmic brain stimulation has emerged as a powerful tool to modulate cognition and to target pathological oscillations related to neurological and psychiatric disorders. However, we lack a systematic understanding of how periodic stimulation interacts with endogenous neural activity as a function of the brai...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aaeb03
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:State of the art brain-computer interface (BCI) research focuses on improving individual components such as the application or the decoder that converts the user's brain activity to control signals. In this study, we investigate the interaction between these components in the P300 speller, a BCI for communica...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066027
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The generalization and robustness of an electroencephalogram (EEG)-based system are crucial requirements in actual practices. APPROACH:To reach these goals, we propose a new EEG representation that provides a more realistic view of brain functionality by applying multi-instance (MI) framework to consider the...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab0dad
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa7a42
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Given the rapid expansion of the field of neural stimulation and the rigorous regulatory approval requirements required before these devices can be applied clinically, it is important that there is clarity around conducting preclinical safety and efficacy studies required for the development of this technolog...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aac43c
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:Fractional calculus plays a key role in the analysis of neural dynamics. In particular, fractional calculus has been recently exploited for analyzing complex biological systems and capturing intrinsic phenomena. Also, artificial neural networks have been shown to have complex neuronal dynamics and characteris...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab8dd6
更新日期:2020-06-12 00:00:00
abstract:OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/5/056018
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Differential measurement of efferent and afferent peripheral nerve activity offers a promising means of improving the clinical utility of implantable neuroprostheses. The tripolar nerve cuff electrode has historically served as the gold standard for achieving high signal-to-noise ratios (SNRs) of the recordin...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa6407
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:In biomagnetic signal processing, the theory of the signal subspace has been applied to removing interfering magnetic fields, and a representative algorithm is the signal space projection algorithm, in which the signal/interference subspace is defined in the spatial domain as the span of signal/interference-s...
journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2552/aa7693
更新日期:2017-10-01 00:00:00
abstract::Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/6/1/016002
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:A visual stimulator plays a vital part in brain-computer interfaces (BCIs) based on steady-state visual evoked potential (SSVEP). The properties of visual stimulation, such as frequency, color, and waveform, will influence SSVEP-based BCI performance to some extent. Recently, the computer monitor serves as a ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab2b7d
更新日期:2019-10-10 00:00:00
abstract:OBJECTIVE:Filter bank canonical correlation analysis (FBCCA) is a widely-used classification approach implemented in steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs). However, conventional detection algorithms for SSVEP recognition problems, including the FBCCA, were usually based on ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab914e
更新日期:2020-05-07 00:00:00
abstract:OBJECTIVE:Loss of even part of the upper limb is a devastating injury. In order to fully restore natural function when lacking sufficient residual musculature, it is necessary to record directly from peripheral nerves. However, current approaches must make trade-offs between signal quality and longevity which limit the...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/4/046007
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Many physical models of biological processes including neural systems are characterized by parametric nonlinear dynamical relations between driving inputs, internal states, and measured outputs of the process. Fitting such models using experimental data (data assimilation) is a challenging task since the phys...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aac3f7
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:Analyzing and interpreting the activity of a heterogeneous population of neurons can be challenging, especially as the number of neurons, experimental trials, and experimental conditions increases. One approach is to extract a set of latent variables that succinctly captures the prominent co-fluctuation patte...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066012
更新日期:2013-12-01 00:00:00
abstract::In this paper, we investigate the influence of hypercapnia on the dynamics of the phrenic neurogram in the piglet in two different age groups: 3-7 days (n = 11) and 10-16 days (n = 9). The phrenic neurogram was recorded from 17 piglets (3-16 days old) during control (40% O(2) with 3-5% end-tidal CO(2)), mild hypercapn...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/2/2/004
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:Advances in electrode technology have facilitated the development of neuroprostheses for restoring motor/sensory function in disabled individuals. Information extracted from a whole nerve, recorded using cuffs, can provide signals that control the operation of neuroprostheses. However, the amount of informati...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab5551
更新日期:2020-01-28 00:00:00