Abstract:
OBJECTIVE:A signal-based metric for assessment of accuracy of motor unit (MU) identification from high-density surface electromyograms (EMG) is introduced. This metric, so-called pulse-to-noise-ratio (PNR), is computationally efficient, does not require any additional experimental costs and can be applied to every MU that is identified by the previously developed convolution kernel compensation technique. APPROACH:The analytical derivation of the newly introduced metric is provided, along with its extensive experimental validation on both synthetic and experimental surface EMG signals with signal-to-noise ratios ranging from 0 to 20 dB and muscle contraction forces from 5% to 70% of the maximum voluntary contraction. MAIN RESULTS:In all the experimental and simulated signals, the newly introduced metric correlated significantly with both sensitivity and false alarm rate in identification of MU discharges. Practically all the MUs with PNR > 30 dB exhibited sensitivity >90% and false alarm rates <2%. Therefore, a threshold of 30 dB in PNR can be used as a simple method for selecting only reliably decomposed units. SIGNIFICANCE:The newly introduced metric is considered a robust and reliable indicator of accuracy of MU identification. The study also shows that high-density surface EMG can be reliably decomposed at contraction forces as high as 70% of the maximum.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Holobar A,Minetto MA,Farina Ddoi
10.1088/1741-2560/11/1/016008subject
Has Abstractpub_date
2014-02-01 00:00:00pages
016008issue
1eissn
1741-2560issn
1741-2552journal_volume
11pub_type
杂志文章abstract:OBJECTIVE:It is known that multi-site interleaved stimulation generates less muscle fatigue compared to single-site synchronous stimulation. However, in the limited number of studies in which intramuscular electrodes were used, the fatigue reduction associated with interleaved stimulation could not consistently be achi...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aba99e
更新日期:2020-08-25 00:00:00
abstract:OBJECTIVE:Tactile afferents in the human hand provide fundamental information about hand-environment interactions, which is used by the brain to adapt the motor output to the physical properties of the object being manipulated. A hand amputation disrupts both afferent and efferent pathways from/to the hand, completely ...
journal_title:Journal of neural engineering
pub_type: 杂志文章,随机对照试验
doi:10.1088/1741-2552/ab059b
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Functions ascribed to the hippocampal sub-regions for encoding episodic memories include the separation of activity patterns propagated from the entorhinal cortex (EC) into the dentate gyrus (DG) and pattern completion in CA3 region. Since a direct assessment of these functions is lacking at the level of spec...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aabc20
更新日期:2018-08-01 00:00:00
abstract::We describe a brain-computer interface for controlling a humanoid robot directly using brain signals obtained non-invasively from the scalp through electroencephalography (EEG). EEG has previously been used for tasks such as controlling a cursor and spelling a word, but it has been regarded as an unlikely candidate fo...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/5/2/012
更新日期:2008-06-01 00:00:00
abstract::The blood oxygenation level dependent (BOLD) contrast has been commonly used to detect fMRI signal. The majority of the BOLD signals are believed to arise from the venous and capillary networks. However, only those from the capillaries are spatially close to the neuronal activities, while the signals from large veins ...
journal_title:Journal of neural engineering
pub_type: 临床试验,杂志文章
doi:10.1088/1741-2560/1/1/005
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential of intracortical electrode array signals for brain-computer interfaces (BCIs) to restore lost speech, we measured the performance of decoders trained to discriminate a comprehensive basis set of 39 English phonemes and to synthesize speech sounds via a neural pattern matching method....
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abbfef
更新日期:2020-11-25 00:00:00
abstract:OBJECTIVE:The clinical use of microsignals recorded over broad cortical regions is largely limited by the chronic reliability of the implanted interfaces. APPROACH:We evaluated the chronic reliability of novel 61-channel micro-electrocorticographic (µECoG) arrays in rats chronically implanted for over one year and usi...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aae39d
更新日期:2018-12-01 00:00:00
abstract::In this paper, we investigate the influence of hypercapnia on the dynamics of the phrenic neurogram in the piglet in two different age groups: 3-7 days (n = 11) and 10-16 days (n = 9). The phrenic neurogram was recorded from 17 piglets (3-16 days old) during control (40% O(2) with 3-5% end-tidal CO(2)), mild hypercapn...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/2/2/004
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066008
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat chronic pain. Computational models represent a valuable tool to study the potential mechanisms of action of SCS and to optimize the design and implementation of SCS technologies. However, it is imperative that these computational mode...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab8fc4
更新日期:2020-06-12 00:00:00
abstract::Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/6/1/016002
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:Electrocorticography (ECoG) based studies generally analyze features from specific frequency bands selected by manual evaluation of spectral power. However, the definition of these features can vary across subjects, cortical areas, tasks and across time for a given subject. We propose an autoencoder based app...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aaf13f
更新日期:2019-02-01 00:00:00
abstract::We investigated the relationships of the firing rate and maximal recruitment threshold of motoneurons recorded during isometric contraction with the number of spindles in individual muscles. At force levels above 10% of maximal voluntary contraction, the firing rate was inversely related to the number of spindles in a...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/1/016007
更新日期:2012-02-01 00:00:00
abstract::Automatic spike sorting is a prerequisite for neuroscience research on multichannel extracellular recordings of neuronal activity. A novel spike sorting framework, combining efficient feature extraction and an unsupervised clustering method, is described here. Wavelet transform (WT) is adopted to extract features from...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/3/036003
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:The majority of near-infrared spectroscopy (NIRS) brain-computer interface (BCI) studies have investigated binary classification problems. Limited work has considered differentiation of more than two mental states, or multi-class differentiation of higher-level cognitive tasks using measurements outside of th...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066008
更新日期:2015-12-01 00:00:00
abstract::In this paper, we propose a simple and straightforward algorithm for neural spike sorting. The algorithm is based on the observation that the distribution of a neural signal largely deviates from the uniform distribution and is rather unimodal. The detected spikes to be sorted are first processed with some feature ext...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/6/066014
更新日期:2011-12-01 00:00:00
abstract::The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/4/046014
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab8e8e
更新日期:2020-06-02 00:00:00
abstract:OBJECTIVE:Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa651f
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/13/4/046013
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Most brain-computer interfaces (BCIs) based on functional near-infrared spectroscopy (fNIRS) require that users perform mental tasks such as motor imagery, mental arithmetic, or music imagery to convey a message or to answer simple yes or no questions. These cognitive tasks usually have no direct association ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aae4b9
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Over the past two decades retinal prostheses have made major strides in restoring functional vision to patients blinded by diseases such as retinitis pigmentosa. Presently, implants use single pulses to activate the retina. Though this stimulation paradigm has proved beneficial to patients, an unresolved prob...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa722c
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:We aim to increase the number of neural spikes that can be detected in a single channel extracellular neural recording. APPROACH:We propose a pre-emphasis method facilitating stochastic resonance (SR), where we introduce the band-pass-filtered noisy extracellular recording to an overdamped Brownian particle ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/abae8a
更新日期:2020-09-18 00:00:00
abstract:OBJECTIVE:We presented a comparative study on the training methodologies of a convolutional neural network (CNN) for the detection of steady-state visually evoked potentials (SSVEP). Two training scenarios were also compared: user-independent (UI) training and user-dependent (UD) training. APPROACH:The CNN was trained...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab6a67
更新日期:2020-04-08 00:00:00
abstract:OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. How...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab53ac
更新日期:2020-01-06 00:00:00
abstract:OBJECTIVE:Among electrophysiological signals, local field potentials (LFPs) are extensively used to study brain activity, either in vivo or in vitro. LFPs are recorded with extracellular electrodes implanted in brain tissue. They reflect intermingled excitatory and inhibitory processes in neuronal assemblies. In cortic...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aafbfb
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab17a0
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:Recording of neural signals from intact peripheral nerves in patients with spinal cord injury or stroke survivors offers the possibility for the development of closed-loop sensorimotor prostheses. Nerve cuffs have been found to provide stable recordings from peripheral nerves for prolonged periods of time. Ho...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aabca0
更新日期:2018-08-01 00:00:00
abstract::The extraction of distinctly separable features from electroencephalogram (EEG) is one of the main challenges in designing a brain-computer interface (BCI). Existing feature extraction techniques for a BCI are mostly developed based on traditional signal processing techniques assuming that the signal is Gaussian and h...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/2/025014
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the benefit of integrating thermal imaging into an artificial vision therapy system, the Argus II retinal prosthesis, in simplifying a complex scene and improving mobility performance in the presence of other persons. APPROACH:Four Argus II retinal implant users were evaluated on two tasks: to lo...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aba4fb
更新日期:2020-08-04 00:00:00