Neurite outgrowth at the interface of 2D and 3D growth environments.

abstract：OBJECTIVE:Due to their increased proximity to retinal ganglion cells (RGCs), epiretinal visual prostheses present the opportunity for eliciting phosphenes with low thresholds through direct RGC activation. This study characterised the in vivo performance of a novel prototype monolithic epiretinal prosthesis, containing...

journal_title：Journal of neural engineering

authors： Shivdasani MN,Evans M,Burns O,Yeoh J,Allen PJ,Nayagam DAX,Villalobos J,Abbott CJ,Luu CD,Opie NL,Sabu A,Saunders AL,McPhedran M,Cardamone L,McGowan C,Maxim V,Williams RA,Fox KE,Cicione R,Garrett DJ,Ahnood A,Ganes

更新日期：2020-08-05 00:00:00

abstract：OBJECTIVE:Low-intensity pulsed ultrasound stimulation (LIPUS) targeted to the mouse motor cortex can simultaneously induce local field potentials (LFPs) and electromyogram (EMG) responses. However, the functional coupling relationship between LFP and EMG signals has not been elucidated to date. This study aimed to inve...

journal_title：Journal of neural engineering

authors： Wang Y,Xie P,Zhou S,Wang X,Yuan Y

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:The majority of near-infrared spectroscopy (NIRS) brain-computer interface (BCI) studies have investigated binary classification problems. Limited work has considered differentiation of more than two mental states, or multi-class differentiation of higher-level cognitive tasks using measurements outside of th...

journal_title：Journal of neural engineering

authors： C Schudlo L,Chau T

更新日期：2015-12-01 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：:This review paper shows that tungsten should not generally be used as a chronically implanted material. The metal has a long implant history, from neuroscience, vascular medicine, radiography, orthopaedics, prosthodontics, and various other fields, primarily as a result of its high density, radiopacity, tensile streng...

journal_title：Journal of neural engineering

authors： Shah Idil A,Donaldson N

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:The advancement of surface electromyogram (sEMG) recording and signal processing techniques has allowed us to characterize the recruitment properties of a substantial population of motor units (MUs) non-invasively. Here we seek to determine whether MU recruitment properties are modified in paretic muscles of ...

journal_title：Journal of neural engineering

authors： Hu X,Suresh AK,Rymer WZ,Suresh NL

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or above the dura mater. Theoretically, the subdural location combines ...

journal_title：Journal of neural engineering

authors： Capogrosso M,Gandar J,Greiner N,Moraud EM,Wenger N,Shkorbatova P,Musienko P,Minev I,Lacour S,Courtine G

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Brain-machine interfaces (BMIs) have been proposed in closed-loop applications for neuromodulation and neurorehabilitation. This study describes the impact of different feedback modalities on the performance of an EEG-based BMI that decodes motor imagery (MI) of leg flexion and extension. APPROACH:We execute...

journal_title：Journal of neural engineering

authors： Liu D,Chen W,Lee K,Chavarriaga R,Bouri M,Pei Z,Del R Millán J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Brain-computer interface (BCI) technology aims to provide individuals with paralysis a means to restore function. Electrocorticography (ECoG) uses disc electrodes placed on either the surface of the dura or the cortex to record field potential activity. ECoG has been proposed as a viable neural recording moda...

journal_title：Journal of neural engineering

authors： Degenhart AD,Hiremath SV,Yang Y,Foldes S,Collinger JL,Boninger M,Tyler-Kabara EC,Wang W

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:The objective of this work is to use the capability of spiking neural networks to capture the spatio-temporal information encoded in time-series signals and decode them without the use of hand-crafted features and vector-based learning and the realization of the spiking model on low-power neuromorphic hardwar...

journal_title：Journal of neural engineering

authors： Behrenbeck J,Tayeb Z,Bhiri C,Richter C,Rhodes O,Kasabov N,Espinosa-Ramos JI,Furber S,Cheng G,Conradt J

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Intracortical brain-machine interfaces (iBMIs) aim to restore efficient communication and movement ability for paralyzed patients. However, frequent recalibration is required for consistency and reliability, and every recalibration will require relatively large most current sample set. The aim in this study i...

journal_title：Journal of neural engineering

authors： Zhang P,Ma X,Chen L,Zhou J,Wang C,Li W,He J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Resting state functional connectivity (RSFC) allows the study of functional organization in normal and diseased brain by measuring the spontaneous brain activity generated under resting conditions. Intrinsic optical signal imaging (IOSI) based on multiple illumination wavelengths has been used successfully to...

journal_title：Journal of neural engineering

authors： Kura S,Xie H,Fu B,Ayata C,Boas DA,Sakadžić S

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:One of the main goals of brain-machine interface (BMI) research is to restore function to people with paralysis. Currently, multiple BMI design features are being investigated, based on various input modalities (externally applied and surgically implantable sensors) and output modalities (e.g. control of comp...

journal_title：Journal of neural engineering

authors： Blabe CH,Gilja V,Chestek CA,Shenoy KV,Anderson KD,Henderson JM

更新日期：2015-08-01 00:00:00

abstract：:The extraction of distinctly separable features from electroencephalogram (EEG) is one of the main challenges in designing a brain-computer interface (BCI). Existing feature extraction techniques for a BCI are mostly developed based on traditional signal processing techniques assuming that the signal is Gaussian and h...

journal_title：Journal of neural engineering

authors： Shahid S,Prasad G

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. APPROACH:We discuss the physical basis of ...

journal_title：Journal of neural engineering

authors： Mierzejewski M,Steins H,Kshirsagar P,Jones PD

更新日期：2020-10-15 00:00:00

abstract：:The functional effects of selective hypoglossal nerve (HG) stimulation with a multi-contact peripheral nerve electrode were assessed using images of the upper airways and the tongue in anesthetized beagles. A biphasic pulse train of 50 Hz frequency and 2 s duration was applied through each one of the tripolar contact ...

journal_title：Journal of neural engineering

authors： Huang J,Sahin M,Durand DM

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP,Ang KK,Tee KP

更新日期：2013-10-01 00:00:00

abstract：:Brain-computer interface (BCI) systems do not work for all users. This article introduces a novel combination of tasks that could inspire BCI systems that are more accurate than conventional BCIs, especially for users who cannot attain accuracy adequate for effective communication. Subjects performed tasks typically u...

journal_title：Journal of neural engineering

authors： Allison BZ,Brunner C,Kaiser V,Müller-Putz GR,Neuper C,Pfurtscheller G

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to characterize the phenomenon of evoked tactile sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical nerve stimulation (TENS). APPROACH:We identified the projected finger map (PFM) of ETS on the stump skin in 11 forearm amputees, and compared percep...

journal_title：Journal of neural engineering

authors： Chai G,Sui X,Li S,He L,Lan N

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Rhythmic brain stimulation has emerged as a powerful tool to modulate cognition and to target pathological oscillations related to neurological and psychiatric disorders. However, we lack a systematic understanding of how periodic stimulation interacts with endogenous neural activity as a function of the brai...

journal_title：Journal of neural engineering

authors： Li G,Henriquez CS,Fröhlich F

更新日期：2019-02-01 00:00:00

abstract：:We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...

journal_title：Journal of neural engineering

authors： Zviagintsev A,Perelman Y,Ginosar R

更新日期：2006-03-01 00:00:00

abstract：:Adaptive model theory (AMT) is a computational theory that addresses the difficult control problem posed by the musculoskeletal system in interaction with the environment. It proposes that the nervous system creates motor maps and task-dependent synergies to solve the problems of redundancy and limited central resourc...

journal_title：Journal of neural engineering

authors： Neilson PD,Neilson MD

更新日期：2005-09-01 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...

journal_title：Journal of neural engineering

authors： Kim BJ,Kuo JT,Hara SA,Lee CD,Yu L,Gutierrez CA,Hoang TQ,Pikov V,Meng E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:Implantable retinal prostheses aim to provide artificial vision to those suffering from retinal degenerative diseases by electrically stimulating the remaining retinal neurons using a multi-electrode array. The spatial resolution of these devices can be improved by creation of so-called virtual channels (VCs)...

journal_title：Journal of neural engineering

authors： Song X,Guo T,Shivdasani MN,Dokos S,Lovell NH,Li X,Qiu S,Li T,Zheng S,Li L

更新日期：2020-10-21 00:00:00

abstract：OBJECTIVE:Most brain-computer interfaces (BCIs) based on functional near-infrared spectroscopy (fNIRS) require that users perform mental tasks such as motor imagery, mental arithmetic, or music imagery to convey a message or to answer simple yes or no questions. These cognitive tasks usually have no direct association ...

journal_title：Journal of neural engineering

authors： Rezazadeh Sereshkeh A,Yousefi R,Wong AT,Chau T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Microwire and Utah-style neural recording arrays are the predominant devices used for cortical neural recording, but the implanted electrodes cause a significant adverse biological response and suffer from well-studied performance degradation. Recent work has demonstrated that carbon fiber electrodes do not e...

journal_title：Journal of neural engineering

authors： Massey TL,Santacruz SR,Hou JF,Pister KSJ,Carmena JM,Maharbiz MM

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Differential measurement of efferent and afferent peripheral nerve activity offers a promising means of improving the clinical utility of implantable neuroprostheses. The tripolar nerve cuff electrode has historically served as the gold standard for achieving high signal-to-noise ratios (SNRs) of the recordin...

journal_title：Journal of neural engineering

authors： Sabetian P,Popovic MR,Yoo PB

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:By means of subjective psychophysical methods, quality of transmitted speech has been decomposed into three perceptual dimensions named 'discontinuity' (F), 'noisiness' (N) and 'coloration' (C). Previous studies using electroencephalography (EEG) already reported effects of perceived intensity of single quali...

journal_title：Journal of neural engineering

authors： Uhrig S,Mittag G,Möller S,Voigt-Antons JN

更新日期：2019-06-01 00:00:00