Creation of virtual channels in the retina using synchronous and asynchronous stimulation - a modelling study.

abstract：OBJECTIVE:Schwann cells (SCs) are primary structural and functional cells in the peripheral nervous system. These cells play a crucial role in peripheral nerve regeneration by releasing neurotrophic factors. This study evaluated the neural differentiation potential effects of stem cells from human exfoliated deciduous ...

journal_title：Journal of neural engineering

authors： Su WT,Pan YJ

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The objective of this work is to use the capability of spiking neural networks to capture the spatio-temporal information encoded in time-series signals and decode them without the use of hand-crafted features and vector-based learning and the realization of the spiking model on low-power neuromorphic hardwar...

journal_title：Journal of neural engineering

authors： Behrenbeck J,Tayeb Z,Bhiri C,Richter C,Rhodes O,Kasabov N,Espinosa-Ramos JI,Furber S,Cheng G,Conradt J

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Penetrating cortical neural probe technologies allow investigators to record electrical signals in the brain. Implantation of probes results in acute tissue damage, and microglia density increases around implanted devices over weeks. However, the mechanisms underlying this encapsulation are not well understoo...

journal_title：Journal of neural engineering

authors： Kozai TD,Vazquez AL,Weaver CL,Kim SG,Cui XT

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Loss of even part of the upper limb is a devastating injury. In order to fully restore natural function when lacking sufficient residual musculature, it is necessary to record directly from peripheral nerves. However, current approaches must make trade-offs between signal quality and longevity which limit the...

journal_title：Journal of neural engineering

authors： Irwin ZT,Schroeder KE,Vu PP,Tat DM,Bullard AJ,Woo SL,Sando IC,Urbanchek MG,Cederna PS,Chestek CA

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Currently, there are some 95 000 people in Europe suffering from upper-limb impairment. Rehabilitation should be undertaken right after the impairment occurs and should be regularly performed thereafter. Moreover, the rehabilitation process should be tailored specifically to both patient and impairment. APPR...

journal_title：Journal of neural engineering

authors： Nissler C,Nowak M,Connan M,Büttner S,Vogel J,Kossyk I,Márton ZC,Castellini C

更新日期：2019-04-01 00:00:00

abstract：:We hypothesize that a visual prosthesis capable of evoking high-resolution visual perceptions can be produced using high-electrode-count arrays of penetrating microelectrodes implanted into the primary visual cortex of a blind human subject. To explore this hypothesis, and as a prelude to human psychophysical experime...

journal_title：Journal of neural engineering

authors： Torab K,Davis TS,Warren DJ,House PA,Normann RA,Greger B

更新日期：2011-06-01 00:00:00

abstract：:Glutamate spillover is thought to play a significant role in increasing neural transmission at the mossy fiber/granule cell cerebellar glomerulus. Glutamate spillover has been shown to activate AMPA receptors at the glomerulus, and here we complete the characterization of spillover at the glomerulus by investigating t...

journal_title：Journal of neural engineering

authors： Mitchell CS,Feng SS,Lee RH

更新日期：2007-09-01 00:00:00

abstract：:The extraction of distinctly separable features from electroencephalogram (EEG) is one of the main challenges in designing a brain-computer interface (BCI). Existing feature extraction techniques for a BCI are mostly developed based on traditional signal processing techniques assuming that the signal is Gaussian and h...

journal_title：Journal of neural engineering

authors： Shahid S,Prasad G

更新日期：2011-04-01 00:00:00

abstract：:Brain-computer interface (BCI) systems do not work for all users. This article introduces a novel combination of tasks that could inspire BCI systems that are more accurate than conventional BCIs, especially for users who cannot attain accuracy adequate for effective communication. Subjects performed tasks typically u...

journal_title：Journal of neural engineering

authors： Allison BZ,Brunner C,Kaiser V,Müller-Putz GR,Neuper C,Pfurtscheller G

更新日期：2010-04-01 00:00:00

abstract：:A motor imagery based brain-computer interface (BCI) provides a non-muscular communication channel that enables people with paralysis to control external devices using their motor imagination. Reducing the number of electrodes is critical to improving the portability and practicability of the BCI system. A novel metho...

journal_title：Journal of neural engineering

authors： Lou B,Hong B,Gao X,Gao S

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:We propose a new hybrid brain-computer interface (BCI) system that integrates two different EEG tasks: tactile selective attention (TSA) using a vibro-tactile stimulator on the left/right finger and motor imagery (MI) of left/right hand movement. Event-related desynchronization (ERD) from the MI task and stea...

journal_title：Journal of neural engineering

authors： Ahn S,Ahn M,Cho H,Chan Jun S

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:We aimed to develop a robotic interface capable of providing finely-tuned, multidirectional trunk assistance adjusted in real-time during unconstrained locomotion in rats and mice. APPROACH:We interfaced a large-scale robotic structure actuated in four degrees of freedom to exchangeable attachment modules e...

journal_title：Journal of neural engineering

authors： von Zitzewitz J,Asboth L,Fumeaux N,Hasse A,Baud L,Vallery H,Courtine G

更新日期：2016-04-01 00:00:00

abstract：:Spastic hypertonus (muscle over-activity due to exaggerated stretch reflexes) often develops in people with stroke, cerebral palsy, multiple sclerosis and spinal cord injury. Lesioning of nerves, e.g. with phenol or botulinum toxin is widely performed to reduce spastic hypertonus. We have explored the use of direct el...

journal_title：Journal of neural engineering

authors： Ravid EN,Gan LS,Todd K,Prochazka A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Electrical status epilepticus during sleep (ESES), as electroencephalographic disturbances, is characterized by strong activation of epileptiform activity in the electroencephalogram during sleep. Quantitative descriptors of such epileptiform activity can support the diagnose and the prognosis of children wit...

journal_title：Journal of neural engineering

authors： Zhao X,Wang X,Chen C,Fan J,Yu X,Wang Z,Akbarzadeh S,Li Q,Zhou S,Chen W

更新日期：2020-08-11 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:In biomagnetic signal processing, the theory of the signal subspace has been applied to removing interfering magnetic fields, and a representative algorithm is the signal space projection algorithm, in which the signal/interference subspace is defined in the spatial domain as the span of signal/interference-s...

journal_title：Journal of neural engineering

authors： Sekihara K,Nagarajan SS

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Damage to the brain, as a result of various medical conditions, impacts the everyday life of patients and there is still no complete cure to neurological disorders. Neuroprostheses that can functionally replace the damaged neural circuit have recently emerged as a possible solution to these problems. Here we ...

journal_title：Journal of neural engineering

authors： Xu T,Xiao N,Zhai X,Kwan Chan P,Tin C

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Spike detection from extracellular recordings is a crucial preprocessing step when analyzing neuronal activity. The decision whether a specific part of the signal is a spike or not is important for any kind of other subsequent preprocessing steps, like spike sorting or burst detection in order to reduce the c...

journal_title：Journal of neural engineering

authors： Lieb F,Stark HG,Thielemann C

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00

abstract：:Rational selection of electrical stimulus parameters for an electronic retinal prosthesis requires knowledge of the electrophysiological responses of retinal neurons to electrical stimuli. In this study, we examined the effects of cathodal and anodal current pulses on the extracellularly recorded responses of OFF and ...

journal_title：Journal of neural engineering

authors： Jensen RJ,Ziv OR,Rizzo JF

更新日期：2005-03-01 00:00:00

abstract：:The aim of this study was to assess the accuracy of the convolution kernel compensation (CKC) method in decomposing high-density surface EMG (HDsEMG) signals from the pennate biceps femoris long-head muscle. Although the CKC method has already been thoroughly assessed in parallel-fibered muscles, there are several fac...

journal_title：Journal of neural engineering

authors： Marateb HR,McGill KC,Holobar A,Lateva ZC,Mansourian M,Merletti R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific ...

journal_title：Journal of neural engineering

authors： Black C,Voigts J,Agrawal U,Ladow M,Santoyo J,Moore C,Jones S

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...

journal_title：Journal of neural engineering

authors： Cai C,Twyford P,Fried S

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Medical implants made of non-biological materials provoke a chronic inflammatory response, resulting in the deposition of a collagenous scar tissue (ST) layer on their surface, that gradually thickens over time. This is a critical problem for neural interfaces. Scar build-up on electrodes results in a progres...

journal_title：Journal of neural engineering

authors： FitzGerald JJ

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:One of the main goals of brain-machine interface (BMI) research is to restore function to people with paralysis. Currently, multiple BMI design features are being investigated, based on various input modalities (externally applied and surgically implantable sensors) and output modalities (e.g. control of comp...

journal_title：Journal of neural engineering

authors： Blabe CH,Gilja V,Chestek CA,Shenoy KV,Anderson KD,Henderson JM

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:The clinical use of microsignals recorded over broad cortical regions is largely limited by the chronic reliability of the implanted interfaces. APPROACH:We evaluated the chronic reliability of novel 61-channel micro-electrocorticographic (µECoG) arrays in rats chronically implanted for over one year and usi...

journal_title：Journal of neural engineering

authors： Woods V,Trumpis M,Bent B,Palopoli-Trojani K,Chiang CH,Wang C,Yu C,Insanally MN,Froemke RC,Viventi J

更新日期：2018-12-01 00:00:00

abstract：:This review paper shows that tungsten should not generally be used as a chronically implanted material. The metal has a long implant history, from neuroscience, vascular medicine, radiography, orthopaedics, prosthodontics, and various other fields, primarily as a result of its high density, radiopacity, tensile streng...

journal_title：Journal of neural engineering

authors： Shah Idil A,Donaldson N

更新日期：2018-04-01 00:00:00