Direct activation of zebrafish neurons by ultrasonic stimulation revealed by whole CNS calcium imaging.

abstract：:With the advent of new designs of visual prostheses for the blind, FDA is faced with developing guidance for evaluating their engineering, safety and patient performance. Visual prostheses are considered significant risk medical devices, and their use in human clinical trials must be approved by FDA under an investiga...

journal_title：Journal of neural engineering

authors： Cohen ED

更新日期：2007-03-01 00:00:00

abstract：:Rational selection of electrical stimulus parameters for an electronic retinal prosthesis requires knowledge of the electrophysiological responses of retinal neurons to electrical stimuli. In this study, we examined the effects of cathodal and anodal current pulses on the extracellularly recorded responses of OFF and ...

journal_title：Journal of neural engineering

authors： Jensen RJ,Ziv OR,Rizzo JF

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Recent advances in neural engineering have restored mobility to people with paralysis, relieved symptoms of movement disorders, reduced chronic pain, restored the sense of hearing, and provided sensory perception to individuals with sensory deficits. APPROACH:This progress was enabled by the team-based, inte...

journal_title：Journal of neural engineering

authors： Ereifej ES,Shell CE,Schofield JS,Charkhkar H,Cuberovic I,Dorval AD,Graczyk EL,Kozai TDY,Otto KJ,Tyler DJ,Welle CG,Widge AS,Zariffa J,Moritz CT,Bourbeau DJ,Marasco PD

更新日期：2019-11-12 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) implemented with real-time functional magnetic resonance imaging (rt-fMRI) use fMRI time-courses from predefined regions of interest (ROIs). To reach best performances, localizer experiments and on-site expert supervision are required for ROI definition. To automate this step,...

journal_title：Journal of neural engineering

authors： Lührs M,Sorger B,Goebel R,Esposito F

更新日期：2017-02-01 00:00:00

abstract：:Glutamate spillover is thought to play a significant role in increasing neural transmission at the mossy fiber/granule cell cerebellar glomerulus. Glutamate spillover has been shown to activate AMPA receptors at the glomerulus, and here we complete the characterization of spillover at the glomerulus by investigating t...

journal_title：Journal of neural engineering

authors： Mitchell CS,Feng SS,Lee RH

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:In biomagnetic signal processing, the theory of the signal subspace has been applied to removing interfering magnetic fields, and a representative algorithm is the signal space projection algorithm, in which the signal/interference subspace is defined in the spatial domain as the span of signal/interference-s...

journal_title：Journal of neural engineering

authors： Sekihara K,Nagarajan SS

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:We presented a comparative study on the training methodologies of a convolutional neural network (CNN) for the detection of steady-state visually evoked potentials (SSVEP). Two training scenarios were also compared: user-independent (UI) training and user-dependent (UD) training. APPROACH:The CNN was trained...

journal_title：Journal of neural engineering

authors： Ravi A,Beni NH,Manuel J,Jiang N

更新日期：2020-04-08 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Fractional calculus plays a key role in the analysis of neural dynamics. In particular, fractional calculus has been recently exploited for analyzing complex biological systems and capturing intrinsic phenomena. Also, artificial neural networks have been shown to have complex neuronal dynamics and characteris...

journal_title：Journal of neural engineering

authors： Lu Q

更新日期：2020-06-12 00:00:00

abstract：OBJECTIVE:In electroencephalographic (EEG) data, signals from distinct sources within the brain are widely spread by volume conduction and superimposed such that sensors receive mixtures of a multitude of signals. This reduction of spatial information strongly hampers single-trial analysis of EEG data as, for example, ...

journal_title：Journal of neural engineering

authors： Sannelli C,Vidaurre C,Müller KR,Blankertz B

更新日期：2016-08-01 00:00:00

abstract：:Spastic hypertonus (muscle over-activity due to exaggerated stretch reflexes) often develops in people with stroke, cerebral palsy, multiple sclerosis and spinal cord injury. Lesioning of nerves, e.g. with phenol or botulinum toxin is widely performed to reduce spastic hypertonus. We have explored the use of direct el...

journal_title：Journal of neural engineering

authors： Ravid EN,Gan LS,Todd K,Prochazka A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Intramuscular electromyography (iEMG) signals, non-invasively recorded, directly from the muscles are used to diagnose various neuromuscular disorders/diseases, also to control rehabilitative and assistive robotic devices. iEMG signals are being potentially used in neurology, kinesiology, rehabilitation, and ...

journal_title：Journal of neural engineering

authors： Ashraf H,Waris A,Gilani SO,Kashif AS,Jamil M,Jochumsen M,Niazi IK

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVE:Retinal prosthetic implants restore partial vision to patients blinded due to outer retinal degeneration, using a camera-guided multielectrode array (MEA) that electrically stimulates surviving retinal neurons. Commercial epi-retinal prostheses use millisecond-scale charge-balanced, symmetric, cathodic-first ...

journal_title：Journal of neural engineering

authors： Chang YC,Haji Ghaffari D,Chow RH,Weiland JD

更新日期：2019-04-01 00:00:00

abstract：:Electrical stimulation of peripheral nerve activates large-diameter fibers before small ones. A physiological recruitment order, from small to large-diameter axons, is desirable in many applications. Previous studies using computer simulations showed that selective activation of small fibers could be achieved by resha...

journal_title：Journal of neural engineering

authors： Lertmanorat Z,Durand DM

更新日期：2004-12-01 00:00:00

abstract：:Improving cortical prostheses requires the development of recording neural interfaces that are efficient in terms of providing maximal control information with minimal interface complexity. While the typical approaches have targeted neurons in the motor cortex with multiple penetrating shanks, an alternative approach ...

journal_title：Journal of neural engineering

authors： Parikh H,Marzullo TC,Kipke DR

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Tactile afferents in the human hand provide fundamental information about hand-environment interactions, which is used by the brain to adapt the motor output to the physical properties of the object being manipulated. A hand amputation disrupts both afferent and efferent pathways from/to the hand, completely ...

journal_title：Journal of neural engineering

authors： Clemente F,Valle G,Controzzi M,Strauss I,Iberite F,Stieglitz T,Granata G,Rossini PM,Petrini F,Micera S,Cipriani C

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Two-dimensional (2D) movement control is an important issue in brain-computer interfaces (BCIs) research because being able to move, for example, a cursor with the brain will enable patients with motor disabilities to control their environment. However, it is still a challenge to continuously control 2D movem...

journal_title：Journal of neural engineering

authors： Xia B,Maysam O,Veser S,Cao L,Li J,Jia J,Xie H,Birbaumer N

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP,Ang KK,Tee KP

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Functions ascribed to the hippocampal sub-regions for encoding episodic memories include the separation of activity patterns propagated from the entorhinal cortex (EC) into the dentate gyrus (DG) and pattern completion in CA3 region. Since a direct assessment of these functions is lacking at the level of spec...

journal_title：Journal of neural engineering

authors： Poli D,Wheeler BC,DeMarse TB,Brewer GJ

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:This study employs a human head model with real skull to demonstrate the feasibility of transcranial acoustoelectric brain imaging (tABI) as a new modality for electrical mapping of deep dipole sources during treatment of epilepsy with much better resolution and accuracy than conventional mapping methods. AP...

journal_title：Journal of neural engineering

authors： Barragan A,Preston C,Alvarez A,Bera T,Qin Y,Weinand M,Kasoff W,Witte RS

更新日期：2020-10-30 00:00:00

abstract：OBJECTIVE:We have previously demonstrated a brain-machine interface neuroprosthetic system that provided continuous control of functional electrical stimulation (FES) and restoration of grasp in a primate model of spinal cord injury (SCI). Predicting intended EMG directly from cortical recordings provides a flexible hi...

journal_title：Journal of neural engineering

authors： Ethier C,Acuna D,Solla SA,Miller LE

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:When designing multiclass motor imagery-based brain-computer interface (MI-BCI), a so-called tangent space mapping (TSM) method utilizing the geometric structure of covariance matrices is an effective technique. This paper aims to introduce a method using TSM for finding accurate operational frequency bands r...

journal_title：Journal of neural engineering

authors： Islam MR,Tanaka T,Molla MKI

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...

journal_title：Journal of neural engineering

authors： Bryan MJ,Martin SA,Cheung W,Rao RP

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The use of natural sounds in auditory Brain-Computer Interfaces (BCI) has been shown to improve classification results and usability. Some auditory BCIs are based on stream segregation, in which the subjects must attend one audio stream and ignore the other(s); these streams include some kind of stimuli to be...

journal_title：Journal of neural engineering

authors： Velasco-Álvarez F,Fernández-Rodríguez Á,Medina-Juliá MT,Ron-Angevin R

更新日期：2021-01-19 00:00:00

abstract：:Deep brain stimulation (DBS) has emerged as an effective treatment for movement disorders; however, the fundamental mechanisms by which DBS works are not well understood. Computational models of DBS can provide insights into these fundamental mechanisms and typically require two steps: calculation of the electrical po...

journal_title：Journal of neural engineering

authors： Zhang TC,Grill WM

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:By means of subjective psychophysical methods, quality of transmitted speech has been decomposed into three perceptual dimensions named 'discontinuity' (F), 'noisiness' (N) and 'coloration' (C). Previous studies using electroencephalography (EEG) already reported effects of perceived intensity of single quali...

journal_title：Journal of neural engineering

authors： Uhrig S,Mittag G,Möller S,Voigt-Antons JN

更新日期：2019-06-01 00:00:00

abstract：:Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...

journal_title：Journal of neural engineering

authors： Kofron CM,Fong VJ,Hoffman-Kim D

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The past two decades have seen dramatic progress in our ability to model brain signals recorded by electroencephalography, functional near-infrared spectroscopy, etc., and to derive real-time estimates of user cognitive state, response, or intent for a variety of purposes: to restore communication by the seve...

journal_title：Journal of neural engineering

authors： Kothe CA,Makeig S

更新日期：2013-10-01 00:00:00

abstract：UNLABELLED:Transcranial Doppler (TCD) was recently introduced as a new brain-computer interface (BCI) modality for detecting task-induced hemispheric lateralization. To date, single-trial discrimination between a lateralized mental activity and a rest state has been demonstrated with long (45 s) activation time periods...

journal_title：Journal of neural engineering

authors： Aleem I,Chau T

更新日期：2013-02-01 00:00:00

abstract：:Brain-computer interfaces (BCIs) can use brain signals from the scalp (EEG), the cortical surface (ECoG), or within the cortex to restore movement control to people who are paralyzed. Like muscle-based skills, BCIs' use requires activity-dependent adaptations in the brain that maintain stable relationships between the...

journal_title：Journal of neural engineering

authors： McFarland DJ,Sarnacki WA,Wolpaw JR

更新日期：2010-06-01 00:00:00