Constant pressure fluid infusion into rat neocortex from implantable microfluidic devices.

abstract：:We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...

journal_title：Journal of neural engineering

authors： Zviagintsev A,Perelman Y,Ginosar R

更新日期：2006-03-01 00:00:00

abstract：:In models of electrical stimulation of the nervous system, the electric potential is typically calculated using the quasi-static approximation. The quasi-static approximation allows Maxwell's equations to be simplified by ignoring capacitive, inductive and wave propagation contributions to the potential. While this si...

journal_title：Journal of neural engineering

authors： Bossetti CA,Birdno MJ,Grill WM

更新日期：2008-03-01 00:00:00

abstract：:The blood oxygenation level dependent (BOLD) contrast has been commonly used to detect fMRI signal. The majority of the BOLD signals are believed to arise from the venous and capillary networks. However, only those from the capillaries are spatially close to the neuronal activities, while the signals from large veins ...

journal_title：Journal of neural engineering

authors： Song AW,Gangstead SL

更新日期：2004-03-01 00:00:00

abstract：:All of the human prosthetic visual systems implanted so far have been achromatic. Schmidt et al. (1996) reported that at low stimulation intensities their subject reported that phosphenes usually had a specific hue, but when the stimulus intensity was increased, they desaturated to white. We speculate here that previo...

journal_title：Journal of neural engineering

authors： Towle V,Pham T,McCaffrey M,Allen D,Troyk PR

更新日期：2020-12-18 00:00:00

abstract：OBJECTIVE:Intracortical brain-machine interfaces (iBMIs) aim to restore efficient communication and movement ability for paralyzed patients. However, frequent recalibration is required for consistency and reliability, and every recalibration will require relatively large most current sample set. The aim in this study i...

journal_title：Journal of neural engineering

authors： Zhang P,Ma X,Chen L,Zhou J,Wang C,Li W,He J

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Neuromusculoskeletal models involve many subject-specific physiological parameters that need to be adjusted to adequately represent muscle properties. Traditionally, neuromusculoskeletal models have been calibrated with a forward-inverse dynamic optimization which is time-consuming and unfeasible for rehabili...

journal_title：Journal of neural engineering

authors： Bueno DR,Montano L

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. APPROACH:We discuss the physical basis of ...

journal_title：Journal of neural engineering

authors： Mierzejewski M,Steins H,Kshirsagar P,Jones PD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:Electroencephalography (EEG) recorded during transcranial alternating current simulation (tACS) is highly desirable in order to investigate brain dynamics during stimulation, but is corrupted by large amplitude stimulation artefacts. Artefact removal algorithms have been presented previously, but with substan...

journal_title：Journal of neural engineering

authors： Kohli S,Casson AJ

更新日期：2020-01-24 00:00:00

abstract：OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

journal_title：Journal of neural engineering

authors： Liu Y,Yu S,Gu X,Cao R,Cui S

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Ultrasounds (US) use in neural engineering is so far mainly limited to ablation through high intensity focused ultrasound, but interesting preliminary results show that low intensity low frequency ultrasound could be used instead to modulate neural activity. However, the extent of this modulatory ability of U...

journal_title：Journal of neural engineering

authors： Meneghetti N,Dedola F,Gavryusev V,Sancataldo G,Turrini L,de Vito G,Tiso N,Vanzi F,Carpaneto J,Cutrone A,Pavone FS,Micera S,Mazzoni A

更新日期：2020-10-14 00:00:00

abstract：OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...

journal_title：Journal of neural engineering

authors： Robinson N,Guan C,Vinod AP,Ang KK,Tee KP

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:A visual stimulator plays a vital part in brain-computer interfaces (BCIs) based on steady-state visual evoked potential (SSVEP). The properties of visual stimulation, such as frequency, color, and waveform, will influence SSVEP-based BCI performance to some extent. Recently, the computer monitor serves as a ...

journal_title：Journal of neural engineering

authors： Chen X,Wang Y,Zhang S,Xu S,Gao X

更新日期：2019-10-10 00:00:00

abstract：:The extraction of distinctly separable features from electroencephalogram (EEG) is one of the main challenges in designing a brain-computer interface (BCI). Existing feature extraction techniques for a BCI are mostly developed based on traditional signal processing techniques assuming that the signal is Gaussian and h...

journal_title：Journal of neural engineering

authors： Shahid S,Prasad G

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The objective of this work is to use the capability of spiking neural networks to capture the spatio-temporal information encoded in time-series signals and decode them without the use of hand-crafted features and vector-based learning and the realization of the spiking model on low-power neuromorphic hardwar...

journal_title：Journal of neural engineering

authors： Behrenbeck J,Tayeb Z,Bhiri C,Richter C,Rhodes O,Kasabov N,Espinosa-Ramos JI,Furber S,Cheng G,Conradt J

更新日期：2019-04-01 00:00:00

abstract：:In a recent paper by Bradberry, Gentili and Contreras-Vidal published in Journal of Neural Engineering (2011, 8 036010), an interesting method for the control of a two-dimensional mouse cursor was proposed, which apparently attained excellent control and good speed with relatively simple techniques. We believe some of...

journal_title：Journal of neural engineering

authors： Poli R,Salvaris M

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Multimodal neuroimaging approaches are beneficial to discover brain functionalities at high spatial and temporal resolution. In our work, a novel material composition of a microECoG device relying on Parylene HT and indium-tin-oxide (ITO) is presented, which facilitates two-photon imaging of Ca2+ signals and ...

journal_title：Journal of neural engineering

authors： Zátonyi A,Madarász M,Szabó Á,Lőrincz T,Hodován R,Rózsa B,Fekete Z

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVE:Assessing an infant's brain development remains a challenge for neuroscientists and pediatricians despite great technological advances. As a non-invasive neuroimaging tool, functional near-infrared spectroscopy (fNIRS) has great advantages in monitoring an infant's brain activity. To explore the dynamic featu...

journal_title：Journal of neural engineering

authors： Liang Z,Minagawa Y,Yang HC,Tian H,Cheng L,Arimitsu T,Takahashi T,Tong Y

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：:Rational selection of electrical stimulus parameters for an electronic retinal prosthesis requires knowledge of the electrophysiological responses of retinal neurons to electrical stimuli. In this study, we examined the effects of cathodal and anodal current pulses on the extracellularly recorded responses of OFF and ...

journal_title：Journal of neural engineering

authors： Jensen RJ,Ziv OR,Rizzo JF

更新日期：2005-03-01 00:00:00

abstract：:Functional mapping of eloquent cortex is a common and necessary component of neurosurgical operative planning. Current electrical stimulation-based techniques are inefficient, can evoke seizures and are prone to false-negative results. Here, we present a novel cortical mapping system that extracts event-related neural...

journal_title：Journal of neural engineering

authors： Cheung C,Chang EF

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Depression is a severe mental disorder. However, the neural mechanisms underlying affective interference (difficulties in directing attention away from negative distractors) in depression patients are still not well-understood. In particular, the connections between brain regions remain unclear. Using the emo...

journal_title：Journal of neural engineering

authors： Guo Z,Wu X,Liu J,Yao L,Hu B

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare the use of muscles appropriate for partial-hand prostheses with those typically used for complete hand devices and to determine whether differences in their underlying neural substrates translate to different levels of myoelectric control. APPROACH:We developed a no...

journal_title：Journal of neural engineering

authors： Dyson M,Barnes J,Nazarpour K

更新日期：2018-10-01 00:00:00

abstract：:Repositioning microelectrodes post-implantation is emerging as a promising approach to achieve long-term reliability in single neuronal recordings. The main goal of this study was to (a) assess glial reaction in response to movement of microelectrodes in the brain post-implantation and (b) determine an optimal window ...

journal_title：Journal of neural engineering

authors： Stice P,Muthuswamy J

更新日期：2009-08-01 00:00:00

abstract：:The peripheral nerves of an amputee's residual limb still carry the information required to provide the robust, natural control signals needed to command a dexterous prosthetic limb. However, these signals are mixed in the volume conductor of the body and extracting them is an unmet challenge. A beamforming algorithm ...

journal_title：Journal of neural engineering

authors： Wodlinger B,Durand DM

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Current brain-computer interface (BCI) studies demonstrate the potential to decode neural signals obtained from structured and trial-based tasks to drive actuators with high performance within the context of these tasks. Ideally, to maximize utility, such systems will be applied to a wide range of behavioral ...

journal_title：Journal of neural engineering

authors： Alasfour A,Gabriel P,Jiang X,Shamie I,Melloni L,Thesen T,Dugan P,Friedman D,Doyle W,Devinsky O,Gonda D,Sattar S,Wang S,Halgren E,Gilja V

更新日期：2019-02-01 00:00:00

abstract：:The functional effects of selective hypoglossal nerve (HG) stimulation with a multi-contact peripheral nerve electrode were assessed using images of the upper airways and the tongue in anesthetized beagles. A biphasic pulse train of 50 Hz frequency and 2 s duration was applied through each one of the tripolar contact ...

journal_title：Journal of neural engineering

authors： Huang J,Sahin M,Durand DM

更新日期：2005-12-01 00:00:00

abstract：:Glutamate spillover is thought to play a significant role in increasing neural transmission at the mossy fiber/granule cell cerebellar glomerulus. Glutamate spillover has been shown to activate AMPA receptors at the glomerulus, and here we complete the characterization of spillover at the glomerulus by investigating t...

journal_title：Journal of neural engineering

authors： Mitchell CS,Feng SS,Lee RH

更新日期：2007-09-01 00:00:00

abstract：:Current treatment concepts for epilepsy are based on continuous drug delivery or electrical stimulation to prevent the occurrence of seizures, exposing the brain and body to a mostly unneeded risk of adverse effects. To address the infrequent occurrence and short duration of epileptic seizures, intelligent implantable...

journal_title：Journal of neural engineering

authors： Dümpelmann M

更新日期：2019-08-01 00:00:00