Neural engineering: the process, applications, and its role in the future of medicine.

abstract：OBJECTIVE:Electroencephalography (EEG) recorded during transcranial alternating current simulation (tACS) is highly desirable in order to investigate brain dynamics during stimulation, but is corrupted by large amplitude stimulation artefacts. Artefact removal algorithms have been presented previously, but with substan...

journal_title：Journal of neural engineering

authors： Kohli S,Casson AJ

更新日期：2020-01-24 00:00:00

abstract：OBJECTIVE:The objective of this work is to present gumpy, a new free and open source Python toolbox designed for hybrid brain-computer interface (BCI). APPROACH:Gumpy provides state-of-the-art algorithms and includes a rich selection of signal processing methods that have been employed by the BCI community over the la...

journal_title：Journal of neural engineering

authors： Tayeb Z,Waniek N,Fedjaev J,Ghaboosi N,Rychly L,Widderich C,Richter C,Braun J,Saveriano M,Cheng G,Conradt J

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:It is known that multi-site interleaved stimulation generates less muscle fatigue compared to single-site synchronous stimulation. However, in the limited number of studies in which intramuscular electrodes were used, the fatigue reduction associated with interleaved stimulation could not consistently be achi...

journal_title：Journal of neural engineering

authors： Eladly A,Del Valle J,Minguillon J,Mercadal B,Becerra-Fajardo L,Navarro X,Ivorra A

更新日期：2020-08-25 00:00:00

abstract：OBJECTIVE:Despite the high number of degrees of freedom of the human hand, most actions of daily life can be executed incorporating only palmar, pincer and lateral grasp. In this study we attempt to discriminate these three different executed reach-and-grasp actions utilizing their EEG neural correlates. APPROACH:In a...

journal_title：Journal of neural engineering

authors： Schwarz A,Ofner P,Pereira J,Sburlea AI,Müller-Putz GR

更新日期：2018-02-01 00:00:00

abstract：:The P300 speller is an example of a brain-computer interface that can restore functionality to victims of neuromuscular disorders. Although the most common application of this system has been communicating language, the properties and constraints of the linguistic domain have not to date been exploited when decoding b...

journal_title：Journal of neural engineering

authors： Speier W,Arnold C,Lu J,Taira RK,Pouratian N

更新日期：2012-02-01 00:00:00

abstract：:The gait outcome measures used in clinical trials of paraplegic locomotor training determine the effectiveness of improved walking function assisted by the functional electrical stimulation (FES) system. Focused on kinematic, kinetic or physiological changes of paraplegic patients, traditional methods cannot quantify ...

journal_title：Journal of neural engineering

authors： Ming D,Bai Y,Liu X,Qi H,Cheng L,Wan B,Hu Y,Wong Y,Luk KD,Leong JC

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...

journal_title：Journal of neural engineering

authors： Thompson DE,Quitadamo LR,Mainardi L,Laghari KU,Gao S,Kindermans PJ,Simeral JD,Fazel-Rezai R,Matteucci M,Falk TH,Bianchi L,Chestek CA,Huggins JE

更新日期：2014-06-01 00:00:00

abstract：:Brain-computer interface (BCI) systems do not work for all users. This article introduces a novel combination of tasks that could inspire BCI systems that are more accurate than conventional BCIs, especially for users who cannot attain accuracy adequate for effective communication. Subjects performed tasks typically u...

journal_title：Journal of neural engineering

authors： Allison BZ,Brunner C,Kaiser V,Müller-Putz GR,Neuper C,Pfurtscheller G

更新日期：2010-04-01 00:00:00

abstract：:We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05%...

journal_title：Journal of neural engineering

authors： Zviagintsev A,Perelman Y,Ginosar R

更新日期：2006-03-01 00:00:00

abstract：:Brain-computer interfaces (BCIs) can use brain signals from the scalp (EEG), the cortical surface (ECoG), or within the cortex to restore movement control to people who are paralyzed. Like muscle-based skills, BCIs' use requires activity-dependent adaptations in the brain that maintain stable relationships between the...

journal_title：Journal of neural engineering

authors： McFarland DJ,Sarnacki WA,Wolpaw JR

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...

journal_title：Journal of neural engineering

authors： Christie BP,Tat DM,Irwin ZT,Gilja V,Nuyujukian P,Foster JD,Ryu SI,Shenoy KV,Thompson DE,Chestek CA

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Currently, there are some 95 000 people in Europe suffering from upper-limb impairment. Rehabilitation should be undertaken right after the impairment occurs and should be regularly performed thereafter. Moreover, the rehabilitation process should be tailored specifically to both patient and impairment. APPR...

journal_title：Journal of neural engineering

authors： Nissler C,Nowak M,Connan M,Büttner S,Vogel J,Kossyk I,Márton ZC,Castellini C

更新日期：2019-04-01 00:00:00

abstract：:Functional electrical stimulation (FES) involves artificial activation of muscles with surface or implanted electrodes to restore motor function in paralyzed individuals. Currently, FES-based prostheses produce only a limited range of movements due to the difficulty associated with identifying patterns of muscle activ...

journal_title：Journal of neural engineering

authors： Johnson LA,Fuglevand AJ

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:We presented a comparative study on the training methodologies of a convolutional neural network (CNN) for the detection of steady-state visually evoked potentials (SSVEP). Two training scenarios were also compared: user-independent (UI) training and user-dependent (UD) training. APPROACH:The CNN was trained...

journal_title：Journal of neural engineering

authors： Ravi A,Beni NH,Manuel J,Jiang N

更新日期：2020-04-08 00:00:00

abstract：OBJECTIVE:While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. APPROACH:We discuss the physical basis of ...

journal_title：Journal of neural engineering

authors： Mierzejewski M,Steins H,Kshirsagar P,Jones PD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:Haptic feedback is crucial when we manipulate objects. Information pertaining to an object's stiffness in particular can help facilitate fine motor control. In this study, we seek to determine whether objects of different stiffness levels can be recognized using haptic feedback provided by transcutaneous elec...

journal_title：Journal of neural engineering

authors： Vargas L,Shin H,Huang HH,Zhu Y,Hu X

更新日期：2019-12-05 00:00:00

abstract：:The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...

journal_title：Journal of neural engineering

authors： Wang L,Mathieson K,Kamins TI,Loudin JD,Galambos L,Goetz G,Sher A,Mandel Y,Huie P,Lavinsky D,Harris JS,Palanker DV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Recording of neural signals from intact peripheral nerves in patients with spinal cord injury or stroke survivors offers the possibility for the development of closed-loop sensorimotor prostheses. Nerve cuffs have been found to provide stable recordings from peripheral nerves for prolonged periods of time. Ho...

journal_title：Journal of neural engineering

authors： Silveira C,Brunton E,Spendiff S,Nazarpour K

更新日期：2018-08-01 00:00:00

abstract：:Current treatment concepts for epilepsy are based on continuous drug delivery or electrical stimulation to prevent the occurrence of seizures, exposing the brain and body to a mostly unneeded risk of adverse effects. To address the infrequent occurrence and short duration of epileptic seizures, intelligent implantable...

journal_title：Journal of neural engineering

authors： Dümpelmann M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity during extracellular stimulation has not been investigated so far. APPROACH:Here, the impact of calcium current reversal on neurotransmitter release duri...

journal_title：Journal of neural engineering

authors： Werginz P,Rattay F

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:A visual stimulator plays a vital part in brain-computer interfaces (BCIs) based on steady-state visual evoked potential (SSVEP). The properties of visual stimulation, such as frequency, color, and waveform, will influence SSVEP-based BCI performance to some extent. Recently, the computer monitor serves as a ...

journal_title：Journal of neural engineering

authors： Chen X,Wang Y,Zhang S,Xu S,Gao X

更新日期：2019-10-10 00:00:00

abstract：OBJECTIVE:Neural reflexes regulate immune responses and homeostasis. Advances in bioelectronic medicine indicate that electrical stimulation of the vagus nerve can be used to treat inflammatory disease, yet the understanding of neural signals that regulate inflammation is incomplete. Current interfaces with the vagus n...

journal_title：Journal of neural engineering

authors： Caravaca AS,Tsaava T,Goldman L,Silverman H,Riggott G,Chavan SS,Bouton C,Tracey KJ,Desimone R,Boyden ES,Sohal HS,Olofsson PS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

journal_title：Journal of neural engineering

authors： Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

更新日期：2020-06-02 00:00:00

abstract：OBJECTIVE:Analyzing and interpreting the activity of a heterogeneous population of neurons can be challenging, especially as the number of neurons, experimental trials, and experimental conditions increases. One approach is to extract a set of latent variables that succinctly captures the prominent co-fluctuation patte...

journal_title：Journal of neural engineering

authors： Cowley BR,Kaufman MT,Butler ZS,Churchland MM,Ryu SI,Shenoy KV,Yu BM

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...

journal_title：Journal of neural engineering

authors： Haufe S,Kim JW,Kim IH,Sonnleitner A,Schrauf M,Curio G,Blankertz B

更新日期：2014-10-01 00:00:00

abstract：:Neural models are increasingly being used as design components of physical systems. In order to best use models in these novel contexts, we must develop design rules that describe how decisions in model construction relate to the functional performance of the resulting system. In the accompanying paper, we described a...

journal_title：Journal of neural engineering

authors： Sorensen ME,DeWeerth SP

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:In electroencephalographic (EEG) data, signals from distinct sources within the brain are widely spread by volume conduction and superimposed such that sensors receive mixtures of a multitude of signals. This reduction of spatial information strongly hampers single-trial analysis of EEG data as, for example, ...

journal_title：Journal of neural engineering

authors： Sannelli C,Vidaurre C,Müller KR,Blankertz B

更新日期：2016-08-01 00:00:00

abstract：:This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...

journal_title：Journal of neural engineering

authors： Dominguez LG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Implantable brain-computer interface (BCI) research promises improvements in human health and enhancements in quality of life. Informed consent of subjects is a central tenet of this research. Rapid advances in neuroscience, and the intimate connection between functioning of the brain and conceptions of the s...

journal_title：Journal of neural engineering

authors： Klein E,Ojemann J

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Somatic symptom disorder (SSD) is a reflection of medically unexplained physical symptoms that lead to distress and impairment in social and occupational functioning. SSD is phenomenologically diagnosed and its neurobiology remains unsolved. APPROACH:In this study, we performed hyper-parameter optimized clas...

journal_title：Journal of neural engineering

authors： Eken A,Çolak B,Bal NB,Kuşman A,Kızılpınar SÇ,Akaslan DS,Baskak B

更新日期：2019-12-16 00:00:00