Selective recovery of fascicular activity in peripheral nerves.

Abstract:

:The peripheral nerves of an amputee's residual limb still carry the information required to provide the robust, natural control signals needed to command a dexterous prosthetic limb. However, these signals are mixed in the volume conductor of the body and extracting them is an unmet challenge. A beamforming algorithm was used to leverage the spatial separation of the fascicular sources, recovering mixed pseudo-spontaneous signals with normalized mean squared error of 0.14 ± 0.10 (n = 12) in an animal model. The method was also applied to a human femoral nerve model using computer simulations and recovered all five fascicular-group signals simultaneously with R(2) = 0.7 ± 0.2 at a signal-to-noise ratio of 0 dB. This technique accurately separated peripheral neural signals, potentially providing the voluntary, natural and robust command signals needed for advanced prosthetic limbs.

journal_name

J Neural Eng

authors

Wodlinger B,Durand DM

doi

10.1088/1741-2560/8/5/056005

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

056005

issue

5

eissn

1741-2560

issn

1741-2552

pii

S1741-2560(11)85114-1

journal_volume

8

pub_type

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