Abstract:
OBJECTIVE:We consider the problem of optimal probing to learn connections in an evoked dynamic network. Such a network, in which each edge measures an input-output relationship between sites in sensor/actuator-space, is relevant to emerging applications in neural mapping and neural connectivity estimation. APPROACH:We show that the problem of scheduling nodes to a probe (i.e., stimulate) amounts to a problem of optimal sensor scheduling. MAIN RESULTS:By formulating the evoked network in state-space, we show that the solution to the greedy probing strategy has a convenient form and, under certain conditions, is optimal over a finite horizon. We adopt an expectation maximization technique to update the state-space parameters in an online fashion and demonstrate the efficacy of the overall approach in a series of detailed numerical examples. SIGNIFICANCE:The proposed method provides a principled means to actively probe time-varying connections in neuronal networks. The overall method can be implemented in real time and is particularly well-suited to applications in stimulation-based cortical mapping in which the underlying network dynamics are changing over time.
journal_name
J Neural Engjournal_title
Journal of neural engineeringauthors
Kafashan M,Ching Sdoi
10.1088/1741-2560/12/6/066011subject
Has Abstractpub_date
2015-12-01 00:00:00pages
066011issue
6eissn
1741-2560issn
1741-2552journal_volume
12pub_type
杂志文章abstract:OBJECTIVE:The goal of this study is to characterize the phenomenon of evoked tactile sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical nerve stimulation (TENS). APPROACH:We identified the projected finger map (PFM) of ETS on the stump skin in 11 forearm amputees, and compared percep...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066002
更新日期:2015-12-01 00:00:00
abstract::Human trials of prototype visual prostheses have successfully elicited visual percepts (phosphenes) in the visual field of implant recipients blinded through retinitis pigmentosa and age-related macular degeneration. Researchers are progressing rapidly towards a device that utilizes individual phosphenes as the elemen...
journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2560/6/3/035009
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:Two-dimensional (2D) movement control is an important issue in brain-computer interfaces (BCIs) research because being able to move, for example, a cursor with the brain will enable patients with motor disabilities to control their environment. However, it is still a challenge to continuously control 2D movem...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/4/046021
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/1/016009
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The past two decades have seen dramatic progress in our ability to model brain signals recorded by electroencephalography, functional near-infrared spectroscopy, etc., and to derive real-time estimates of user cognitive state, response, or intent for a variety of purposes: to restore communication by the seve...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/5/056014
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Multimodal neuroimaging approaches are beneficial to discover brain functionalities at high spatial and temporal resolution. In our work, a novel material composition of a microECoG device relying on Parylene HT and indium-tin-oxide (ITO) is presented, which facilitates two-photon imaging of Ca2+ signals and ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/ab603f
更新日期:2020-02-18 00:00:00
abstract:OBJECTIVE:The reliable estimation of parameters such as mean or covariance matrix from noisy and high-dimensional observations is a prerequisite for successful application of signal processing and machine learning algorithms in brain-computer interfacing (BCI). This challenging task becomes significantly more difficult...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa8232
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/045002
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:Cochlear implants, while providing significant benefits to recipients, remain limited due to broad neural activation. Focussed multipolar stimulation (FMP) is an advanced stimulation strategy that uses multiple current sources to produce highly focussed patterns of neural excitation in order to overcome these...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aad0a5
更新日期:2018-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1088/1741-2552/abb63a
更新日期:2020-10-30 00:00:00
abstract:OBJECTIVE:A signal-based metric for assessment of accuracy of motor unit (MU) identification from high-density surface electromyograms (EMG) is introduced. This metric, so-called pulse-to-noise-ratio (PNR), is computationally efficient, does not require any additional experimental costs and can be applied to every MU t...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/1/016008
更新日期:2014-02-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aabc20
更新日期:2018-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1088/1741-2560/6/2/026004
更新日期:2009-04-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/3/036003
更新日期:2011-06-01 00:00:00
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journal_title:Journal of neural engineering
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doi:10.1088/1741-2552/aae8d9
更新日期:2019-02-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 临床试验,杂志文章
doi:10.1088/1741-2560/1/1/005
更新日期:2004-03-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2560/6/1/012001
更新日期:2009-02-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/6/066013
更新日期:2011-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1088/1741-2560/3/2/008
更新日期:2006-06-01 00:00:00
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doi:10.1088/1741-2552/abd463
更新日期:2020-12-16 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/046014
更新日期:2013-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1088/1741-2560/9/3/036007
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pub_type: 杂志文章
doi:10.1088/1741-2560/4/1/S10
更新日期:2007-03-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa58f5
更新日期:2017-04-01 00:00:00
abstract::Retinal implants have proven their ability to restore visual sensation to people with degenerative retinopathy, characterized by photoreceptor cell death and the retina's inability to sense light. Retinal bionics operate by electrically stimulating the surviving neurons in the retina, thus triggering the transfer of v...
journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2552/aa6cbb
更新日期:2017-08-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/8/5/056005
更新日期:2011-10-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aa7a42
更新日期:2017-12-01 00:00:00
abstract::The functional effects of selective hypoglossal nerve (HG) stimulation with a multi-contact peripheral nerve electrode were assessed using images of the upper airways and the tongue in anesthetized beagles. A biphasic pulse train of 50 Hz frequency and 2 s duration was applied through each one of the tripolar contact ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/2/4/002
更新日期:2005-12-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/5/056011
更新日期:2014-10-01 00:00:00
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journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2552/aae0c9
更新日期:2018-12-01 00:00:00