Laboratory investigation of microelectronics-based stimulators for large-scale suprachoroidal transretinal stimulation (STS).

abstract：OBJECTIVE:To evaluate the potential of intracortical electrode array signals for brain-computer interfaces (BCIs) to restore lost speech, we measured the performance of decoders trained to discriminate a comprehensive basis set of 39 English phonemes and to synthesize speech sounds via a neural pattern matching method....

journal_title：Journal of neural engineering

authors： Wilson GH,Stavisky SD,Willett FR,Avansino DT,Kelemen JN,Hochberg LR,Henderson JM,Druckmann S,Shenoy KV

更新日期：2020-11-25 00:00:00

abstract：:To study cell-field dynamics, physiologists simultaneously record local field potentials and the activity of individual cells from animals performing cognitive tasks, during various brain states or under pathological conditions. However, apart from spike shape and spike timing analyses, few studies have focused on elu...

journal_title：Journal of neural engineering

authors： Cotic M,Chiu AW,Jahromi SS,Carlen PL,Bardakjian BL

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Retinal prosthetic implants restore partial vision to patients blinded due to outer retinal degeneration, using a camera-guided multielectrode array (MEA) that electrically stimulates surviving retinal neurons. Commercial epi-retinal prostheses use millisecond-scale charge-balanced, symmetric, cathodic-first ...

journal_title：Journal of neural engineering

authors： Chang YC,Haji Ghaffari D,Chow RH,Weiland JD

更新日期：2019-04-01 00:00:00

abstract：:In models of electrical stimulation of the nervous system, the electric potential is typically calculated using the quasi-static approximation. The quasi-static approximation allows Maxwell's equations to be simplified by ignoring capacitive, inductive and wave propagation contributions to the potential. While this si...

journal_title：Journal of neural engineering

authors： Bossetti CA,Birdno MJ,Grill WM

更新日期：2008-03-01 00:00:00

abstract：:This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...

journal_title：Journal of neural engineering

authors： Dominguez LG

更新日期：2009-10-01 00:00:00

abstract：:The aim of this study was to assess the accuracy of the convolution kernel compensation (CKC) method in decomposing high-density surface EMG (HDsEMG) signals from the pennate biceps femoris long-head muscle. Although the CKC method has already been thoroughly assessed in parallel-fibered muscles, there are several fac...

journal_title：Journal of neural engineering

authors： Marateb HR,McGill KC,Holobar A,Lateva ZC,Mansourian M,Merletti R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Haptic feedback is crucial when we manipulate objects. Information pertaining to an object's stiffness in particular can help facilitate fine motor control. In this study, we seek to determine whether objects of different stiffness levels can be recognized using haptic feedback provided by transcutaneous elec...

journal_title：Journal of neural engineering

authors： Vargas L,Shin H,Huang HH,Zhu Y,Hu X

更新日期：2019-12-05 00:00:00

abstract：OBJECTIVE:We have previously demonstrated a brain-machine interface neuroprosthetic system that provided continuous control of functional electrical stimulation (FES) and restoration of grasp in a primate model of spinal cord injury (SCI). Predicting intended EMG directly from cortical recordings provides a flexible hi...

journal_title：Journal of neural engineering

authors： Ethier C,Acuna D,Solla SA,Miller LE

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...

journal_title：Journal of neural engineering

authors： Christie BP,Tat DM,Irwin ZT,Gilja V,Nuyujukian P,Foster JD,Ryu SI,Shenoy KV,Thompson DE,Chestek CA

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:The advancement of surface electromyogram (sEMG) recording and signal processing techniques has allowed us to characterize the recruitment properties of a substantial population of motor units (MUs) non-invasively. Here we seek to determine whether MU recruitment properties are modified in paretic muscles of ...

journal_title：Journal of neural engineering

authors： Hu X,Suresh AK,Rymer WZ,Suresh NL

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...

journal_title：Journal of neural engineering

authors： Tan DW,Schiefer MA,Keith MW,Anderson JR,Tyler DJ

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...

journal_title：Journal of neural engineering

authors： Cai C,Twyford P,Fried S

更新日期：2013-06-01 00:00:00

abstract：:Retinal implants have proven their ability to restore visual sensation to people with degenerative retinopathy, characterized by photoreceptor cell death and the retina's inability to sense light. Retinal bionics operate by electrically stimulating the surviving neurons in the retina, thus triggering the transfer of v...

journal_title：Journal of neural engineering

authors： Bareket L,Barriga-Rivera A,Zapf MP,Lovell NH,Suaning GJ

更新日期：2017-08-01 00:00:00

abstract：:Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...

journal_title：Journal of neural engineering

authors： Duke AR,Lu H,Jenkins MW,Chiel HJ,Jansen ED

更新日期：2012-06-01 00:00:00

abstract：:Human trials of prototype visual prostheses have successfully elicited visual percepts (phosphenes) in the visual field of implant recipients blinded through retinitis pigmentosa and age-related macular degeneration. Researchers are progressing rapidly towards a device that utilizes individual phosphenes as the elemen...

journal_title：Journal of neural engineering

authors： Chen SC,Suaning GJ,Morley JW,Lovell NH

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:This paper discusses the invariance and variability in interaction error-related potentials (ErrPs), where a special focus is laid upon the factors of (1) the human mental processing required to assess interface actions (2) time (3) subjects. APPROACH:Three different experiments were designed as to vary prim...

journal_title：Journal of neural engineering

authors： Abu-Alqumsan M,Kapeller C,Hintermüller C,Guger C,Peer A

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The goal of this study is to characterize the phenomenon of evoked tactile sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical nerve stimulation (TENS). APPROACH:We identified the projected finger map (PFM) of ETS on the stump skin in 11 forearm amputees, and compared percep...

journal_title：Journal of neural engineering

authors： Chai G,Sui X,Li S,He L,Lan N

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Contemporary deep brain stimulation (DBS) for Parkinson's disease is delivered continuously, and adjustments based on patient's changing symptoms must be made manually by a trained clinician. Patients may be subjected to energy intensive settings at times when they are not needed, possibly resulting in stimul...

journal_title：Journal of neural engineering

authors： Swann NC,de Hemptinne C,Thompson MC,Miocinovic S,Miller AM,Gilron R,Ostrem JL,Chizeck HJ,Starr PA

更新日期：2018-08-01 00:00:00

abstract：:Microscopic aggregation assay and impedance sensing (IS) were used to monitor a change in in vitro neuron-neuron adhesion in response to blocking of cell adhesion molecules. By blocking neuron-neuron adhesion, migration and aggregation of neuronal cells can be inhibited. This leads to better control of spatial arrange...

journal_title：Journal of neural engineering

authors： Wiertz RW,Marani E,Rutten WL

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Electrical status epilepticus during sleep (ESES), as electroencephalographic disturbances, is characterized by strong activation of epileptiform activity in the electroencephalogram during sleep. Quantitative descriptors of such epileptiform activity can support the diagnose and the prognosis of children wit...

journal_title：Journal of neural engineering

authors： Zhao X,Wang X,Chen C,Fan J,Yu X,Wang Z,Akbarzadeh S,Li Q,Zhou S,Chen W

更新日期：2020-08-11 00:00:00

abstract：:We consider the problem of desynchronizing a network of synchronized, globally (all-to-all) coupled neurons using an input to a single neuron. This is done by applying the discrete time dynamic programming method to reduced phase models for neural populations. This technique numerically minimizes a certain cost functi...

journal_title：Journal of neural engineering

authors： Nabi A,Moehlis J

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...

journal_title：Journal of neural engineering

authors： Bryan MJ,Martin SA,Cheung W,Rao RP

更新日期：2013-12-01 00:00:00

abstract：:Rational selection of electrical stimulus parameters for an electronic retinal prosthesis requires knowledge of the electrophysiological responses of retinal neurons to electrical stimuli. In this study, we examined the effects of cathodal and anodal current pulses on the extracellularly recorded responses of OFF and ...

journal_title：Journal of neural engineering

authors： Jensen RJ,Ziv OR,Rizzo JF

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:While the positive correlation between impedance and noise of microelectrodes is well known, their quantitative relationship is too rarely described. Knowledge of this relationship provides useful information for both microsystems engineers and electrophysiologists. APPROACH:We discuss the physical basis of ...

journal_title：Journal of neural engineering

authors： Mierzejewski M,Steins H,Kshirsagar P,Jones PD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...

journal_title：Journal of neural engineering

authors： Haufe S,Kim JW,Kim IH,Sonnleitner A,Schrauf M,Curio G,Blankertz B

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Two-dimensional (2D) movement control is an important issue in brain-computer interfaces (BCIs) research because being able to move, for example, a cursor with the brain will enable patients with motor disabilities to control their environment. However, it is still a challenge to continuously control 2D movem...

journal_title：Journal of neural engineering

authors： Xia B,Maysam O,Veser S,Cao L,Li J,Jia J,Xie H,Birbaumer N

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:Implantable retinal prostheses aim to provide artificial vision to those suffering from retinal degenerative diseases by electrically stimulating the remaining retinal neurons using a multi-electrode array. The spatial resolution of these devices can be improved by creation of so-called virtual channels (VCs)...

journal_title：Journal of neural engineering

authors： Song X,Guo T,Shivdasani MN,Dokos S,Lovell NH,Li X,Qiu S,Li T,Zheng S,Li L

更新日期：2020-10-21 00:00:00

abstract：:Significant progress has been made in systems that interpret the electrical signals of the brain in order to control an actuator. One version of these systems senses neuronal extracellular action potentials with an array of up to 100 miniature probes inserted into the cortex. The impedance of each probe is high, so en...

journal_title：Journal of neural engineering

authors： Jochum T,Denison T,Wolf P

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:We propose a new hybrid brain-computer interface (BCI) system that integrates two different EEG tasks: tactile selective attention (TSA) using a vibro-tactile stimulator on the left/right finger and motor imagery (MI) of left/right hand movement. Event-related desynchronization (ERD) from the MI task and stea...

journal_title：Journal of neural engineering

authors： Ahn S,Ahn M,Cho H,Chan Jun S

更新日期：2014-12-01 00:00:00

abstract：:One of the most important stages in a brain-computer interface (BCI) system is that of extracting features that can reliably discriminate data recorded during different user states. A popular technique used for feature extraction in BCIs is the common spatial patterns (CSP) method, which provides a set of spatial filt...

journal_title：Journal of neural engineering

authors： Falzon O,Camilleri KP,Muscat J

更新日期：2012-08-01 00:00:00