Symbolic time series analysis of fNIRS signals in brain development assessment.

Abstract:

OBJECTIVE:Assessing an infant's brain development remains a challenge for neuroscientists and pediatricians despite great technological advances. As a non-invasive neuroimaging tool, functional near-infrared spectroscopy (fNIRS) has great advantages in monitoring an infant's brain activity. To explore the dynamic features of hemodynamic changes in infants, in-pattern exponent (IPE), anti-pattern exponent (APE), as well as permutation cross-mutual information (PCMI) based on symbolic dynamics are proposed to measure the phase differences and coupling strength in oxyhemoglobin (HbO) and deoxyhemoglobin (Hb) signals from fNIRS. APPROACH:First, simulated sinusoidal oscillation signals and four coupled nonlinear systems were employed for performance assessments. Hilbert transform based measurements of hemoglobin phase oxygenation and deoxygenation (hPod) and phase-locking index of hPod (hPodL) were calculated for comparison. Then, the IPE, APE and PCMI indices from resting state fNIRS data of preterm, term infants and adults were calculated to estimate the phase difference and coupling of HbO and Hb. All indices' performance was assessed by the degree of monotonicity (DoM). The box plots and coefficients of variation (CV) were employed to assess the measurements and robustness in the results. MAIN RESULTS:In the simulation analysis, IPE and APE can distinguish the phase difference of two sinusoidal oscillation signals. Both hPodL and PCMI can track the strength of two coupled nonlinear systems. Compared to hPodL, the PCMI had higher DoM indices in measuring the coupling of two nonlinear systems. In the fNIRS data analysis, similar to hPod, the IPE and APE can distinguish preterm, term infants, and adults in 0.01-0.05 Hz, 0.05-0.1 Hz, and 0.01-0.1 Hz frequency bands, respectively. PCMI more effectively distinguished the term and preterm infants than hPodL in the 0.05-0.1 Hz frequency band. As symbolic time series measures, the IPE and APE were able to detect the brain developmental changes in subjects of different ages. PCMI can assess the resting-state HbO and Hb coupling changes across different developmental ages, which may reflect the metabolic and neurovascular development. SIGNIFICANCE:The symbolic-based methodologies are promising measures for fNIRS in estimating the brain development, especially in assessing newborns' brain developmental status.

journal_name

J Neural Eng

authors

Liang Z,Minagawa Y,Yang HC,Tian H,Cheng L,Arimitsu T,Takahashi T,Tong Y

doi

10.1088/1741-2552/aae0c9

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

066013

issue

6

eissn

1741-2560

issn

1741-2552

journal_volume

15

pub_type

杂志文章
  • Corrigendum: Tissue-engineered nerve grafts using a scaffold-independent and injectable drug delivery system: a novel design with translational advantages (2019 J. Neural Eng. 16 036030).

    abstract:OBJECTIVE:Currently commercially available nerve conduits have demonstrated suboptimal clinical efficacy in repairing peripheral nerve defects. Although tissue-engineered nerve grafts (TENGs) with sustained release of neurotrophic factors (NTFs) are experimentally proved to be more effective than these blank conduits, ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/abd1ec

    authors: Liu Y,Yu S,Gu X,Cao R,Cui S

    更新日期:2020-12-09 00:00:00

  • Neurite outgrowth at the interface of 2D and 3D growth environments.

    abstract::Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/6/1/016002

    authors: Kofron CM,Fong VJ,Hoffman-Kim D

    更新日期:2009-02-01 00:00:00

  • Probabilistic co-adaptive brain-computer interfacing.

    abstract:OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/10/6/066008

    authors: Bryan MJ,Martin SA,Cheung W,Rao RP

    更新日期:2013-12-01 00:00:00

  • Assessment of brain-machine interfaces from the perspective of people with paralysis.

    abstract:OBJECTIVE:One of the main goals of brain-machine interface (BMI) research is to restore function to people with paralysis. Currently, multiple BMI design features are being investigated, based on various input modalities (externally applied and surgically implantable sensors) and output modalities (e.g. control of comp...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/12/4/043002

    authors: Blabe CH,Gilja V,Chestek CA,Shenoy KV,Anderson KD,Henderson JM

    更新日期:2015-08-01 00:00:00

  • Digital filters for low-latency quantification of brain rhythms in real time.

    abstract:OBJECTIVE:The rapidly developing paradigm of closed-loop neuroscience has extensively employed brain rhythms as the signal forming real-time neurofeedback, triggering brain stimulation, or governing stimulus selection. However, the efficacy of brain rhythm contingent paradigms suffers from significant delays related to...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab890f

    authors: Smetanin N,Belinskaya A,Lebedev M,Ossadtchi A

    更新日期:2020-08-04 00:00:00

  • In vivo polymerization of poly(3,4-ethylenedioxythiophene) in the living rat hippocampus does not cause a significant loss of performance in a delayed alternation task.

    abstract::After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/11/2/026005

    authors: Ouyang L,Shaw CL,Kuo CC,Griffin AL,Martin DC

    更新日期:2014-04-01 00:00:00

  • Dynamics and coupling of fractional-order models of the motor cortex and central pattern generators.

    abstract:OBJECTIVE:Fractional calculus plays a key role in the analysis of neural dynamics. In particular, fractional calculus has been recently exploited for analyzing complex biological systems and capturing intrinsic phenomena. Also, artificial neural networks have been shown to have complex neuronal dynamics and characteris...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab8dd6

    authors: Lu Q

    更新日期:2020-06-12 00:00:00

  • An improved P300 pattern in BCI to catch user's attention.

    abstract:OBJECTIVE:Brain-computer interfaces (BCIs) can help patients who have lost control over most muscles but are still conscious and able to communicate or interact with the environment. One of the most popular types of BCI is the P300-based BCI. With this BCI, users are asked to count the number of appearances of target s...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/aa6213

    authors: Jin J,Zhang H,Daly I,Wang X,Cichocki A

    更新日期:2017-06-01 00:00:00

  • Pavlovian control of intraspinal microstimulation to produce over-ground walking.

    abstract:OBJECTIVE:Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive co...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab8e8e

    authors: Dalrymple AN,Roszko DA,Sutton RS,Mushahwar VK

    更新日期:2020-06-02 00:00:00

  • Extracellular voltage thresholds for maximizing information extraction in primate auditory cortex: implications for a brain computer interface.

    abstract:OBJECTIVE:Research by Oby et al (2016) demonstrated that the optimal threshold for extracting information from visual and motor cortices may differ from the optimal threshold for identifying single neurons via spike sorting methods. The optimal threshold for extracting information from auditory cortex has yet to be ide...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab7c19

    authors: Bigelow J,Malone B

    更新日期:2020-03-03 00:00:00

  • Acoustoelectric imaging of deep dipoles in a human head phantom for guiding treatment of epilepsy.

    abstract:OBJECTIVE:This study employs a human head model with real skull to demonstrate the feasibility of transcranial acoustoelectric brain imaging (tABI) as a new modality for electrical mapping of deep dipole sources during treatment of epilepsy with much better resolution and accuracy than conventional mapping methods. AP...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/abb63a

    authors: Barragan A,Preston C,Alvarez A,Bera T,Qin Y,Weinand M,Kasoff W,Witte RS

    更新日期:2020-10-30 00:00:00

  • Post-implantation impedance spectroscopy of subretinal micro-electrode arrays, OCT imaging and numerical simulation: towards a more precise neuroprosthesis monitoring tool.

    abstract:OBJECTIVE:Previous studies have shown that single-frequency impedance measurements could provide useful information about the distance between the neuroprosthesis and the retina. This work investigates the use of impedance spectroscopy in monitoring subretinal implantations of flexible micro-electrode arrays and focuse...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/10/4/046002

    authors: Pham P,Roux S,Matonti F,Dupont F,Agache V,Chavane F

    更新日期:2013-08-01 00:00:00

  • Decoding overt shifts of attention in depth through pupillary and cortical frequency tagging.

    abstract:OBJECTIVE:We have recently developed a prototype of a novel human-computer interface for assistive communication based on voluntary shifts of attention (gaze) from a far target to a near target associated with a decrease of pupil size (Pupillary Accommodative Response, PAR), an automatic vegetative response that can be...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab8e8f

    authors: de'Sperati C,Roatta S,Zovetti N,Baroni T

    更新日期:2020-04-29 00:00:00

  • EEG representation using multi-instance framework on the manifold of symmetric positive definite matrices.

    abstract:OBJECTIVE:The generalization and robustness of an electroencephalogram (EEG)-based system are crucial requirements in actual practices. APPROACH:To reach these goals, we propose a new EEG representation that provides a more realistic view of brain functionality by applying multi-instance (MI) framework to consider the...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab0dad

    authors: Sadatnejad K,Rahmati M,Rostami R,Kazemi R,Ghidary SS,Müller A,Alimardani F

    更新日期:2019-06-01 00:00:00

  • Motor cortex stimulation for Parkinson's disease: a modelling study.

    abstract::Chronic motor cortex stimulation (MCS) is currently being investigated as a treatment method for Parkinson's disease (PD). Unfortunately, the underlying mechanisms of this treatment are unclear and there are many uncertainties regarding the most effective stimulation parameters and electrode configuration. In this pap...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/9/5/056005

    authors: Zwartjes DG,Heida T,Feirabend HK,Janssen ML,Visser-Vandewalle V,Martens HC,Veltink PH

    更新日期:2012-10-01 00:00:00

  • The response of retinal neurons to high-frequency stimulation.

    abstract:OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/10/3/036009

    authors: Cai C,Twyford P,Fried S

    更新日期:2013-06-01 00:00:00

  • Laboratory investigation of microelectronics-based stimulators for large-scale suprachoroidal transretinal stimulation (STS).

    abstract::This paper describes the technological developments underlying the realization of a reliable and reproducible microchip-based stimulator with a large number of stimulus electrodes. A microchip-based stimulator with over 500 electrodes for suprachoroidal transretinal stimulation (STS) is proposed in this paper, and an ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/4/1/S10

    authors: Ohta J,Tokuda T,Kagawa K,Sugitani S,Taniyama M,Uehara A,Terasawa Y,Nakauchi K,Fujikado T,Tano Y

    更新日期:2007-03-01 00:00:00

  • Influence of proprioceptive feedback on the firing rate and recruitment of motoneurons.

    abstract::We investigated the relationships of the firing rate and maximal recruitment threshold of motoneurons recorded during isometric contraction with the number of spindles in individual muscles. At force levels above 10% of maximal voluntary contraction, the firing rate was inversely related to the number of spindles in a...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/9/1/016007

    authors: De Luca CJ,Kline JC

    更新日期:2012-02-01 00:00:00

  • On the risk of extracting relevant information from random data.

    abstract::This comment constitutes a re-assessment of a recent study in which near-infrared spectroscopy (NIRS) was used to decode decision making. In the original study, the process of feature selection was carried out on all of the data, and those features which displayed the greater classification accuracy were selected, but...

    journal_title:Journal of neural engineering

    pub_type: 评论,杂志文章

    doi:10.1088/1741-2560/6/5/058001

    authors: Dominguez LG

    更新日期:2009-10-01 00:00:00

  • Data augmentation for self-paced motor imagery classification with C-LSTM.

    abstract:OBJECTIVE:Brain-computer interfaces (BCI) are becoming important tools for assistive technology, particularly through the use of motor imagery (MI) for aiding task completion. However, most existing methods of MI classification have been applied in a trial-wise fashion, with window sizes of approximately 2 s or more. A...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab57c0

    authors: Freer D,Yang GZ

    更新日期:2020-01-31 00:00:00

  • Comment on 'fast attainment of computer cursor control with noninvasively acquired brain signals'.

    abstract::In a recent paper by Bradberry, Gentili and Contreras-Vidal published in Journal of Neural Engineering (2011, 8 036010), an interesting method for the control of a two-dimensional mouse cursor was proposed, which apparently attained excellent control and good speed with relatively simple techniques. We believe some of...

    journal_title:Journal of neural engineering

    pub_type: 评论,杂志文章

    doi:10.1088/1741-2560/8/5/058001

    authors: Poli R,Salvaris M

    更新日期:2011-10-01 00:00:00

  • Visual cortex responses to suprachoroidal electrical stimulation of the retina: effects of electrode return configuration.

    abstract::A clinically effective retinal prosthesis must evoke localized phosphenes in a retinotopic manner in response to stimulation of each of the retinal electrodes, evoke brightness cues over a wide dynamic range and function within safe stimulus limits. The effects of varying return configuration for retinal stimulation a...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/9/3/036009

    authors: Cicione R,Shivdasani MN,Fallon JB,Luu CD,Allen PJ,Rathbone GD,Shepherd RK,Williams CE

    更新日期:2012-06-01 00:00:00

  • A framework for designing data-driven optimization systems for neural modulation.

    abstract:OBJECTIVE:Neural modulation is a fundamental tool for understanding and treating neurological and psychiatric diseases. However, due to the high-dimensional space, subject-specific responses, and variability within each subject, it is a major challenge to select the stimulation parameters that have the desired effect. ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/abd048

    authors: Connolly MJ,Park SE,Laxpati NG,Zaidi SA,Ghetiya M,Fernandez A,Gutekunst CA,Gross RE

    更新日期:2020-12-03 00:00:00

  • Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation.

    abstract:OBJECTIVE:Given current clinical interest in vagus nerve stimulation (VNS), there are surprisingly few studies characterizing the anatomy of the vagus nerve in large animal models as it pertains to on-and off-target engagement of local fibers. We sought to address this gap by evaluating vagal anatomy in the pig, whose ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/ab7ad4

    authors: Settell ML,Pelot NA,Knudsen BE,Dingle AM,McConico AL,Nicolai EN,Trevathan JK,Ezzell JA,Ross EK,Gustafson KJ,Shoffstall AJ,Williams JC,Zeng W,Poore SO,Populin LC,Suminski AJ,Grill WM,Ludwig KA

    更新日期:2020-04-09 00:00:00

  • Inclusion of temporal priors for automated neonatal EEG classification.

    abstract::The aim of this paper is to use recent advances in the clinical understanding of the temporal evolution of seizure burden in neonates with hypoxic ischemic encephalopathy to improve the performance of automated detection algorithms. Probabilistic weights are designed from temporal locations of neonatal seizure events ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/9/4/046002

    authors: Temko A,Stevenson N,Marnane W,Boylan G,Lightbody G

    更新日期:2012-08-01 00:00:00

  • Analysis of spontaneous MEG activity in mild cognitive impairment and Alzheimer's disease using spectral entropies and statistical complexity measures.

    abstract::Alzheimer's disease (AD) is the most common cause of dementia. Over the last few years, a considerable effort has been devoted to exploring new biomarkers. Nevertheless, a better understanding of brain dynamics is still required to optimize therapeutic strategies. In this regard, the characterization of mild cognitive...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/9/3/036007

    authors: Bruña R,Poza J,Gómez C,García M,Fernández A,Hornero R

    更新日期:2012-06-01 00:00:00

  • Stimulation strategies for selective activation of retinal ganglion cell soma and threshold reduction.

    abstract:OBJECTIVE:Retinal prosthetic implants restore partial vision to patients blinded due to outer retinal degeneration, using a camera-guided multielectrode array (MEA) that electrically stimulates surviving retinal neurons. Commercial epi-retinal prostheses use millisecond-scale charge-balanced, symmetric, cathodic-first ...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2552/aaf92b

    authors: Chang YC,Haji Ghaffari D,Chow RH,Weiland JD

    更新日期:2019-04-01 00:00:00

  • Integrated circuit amplifiers for multi-electrode intracortical recording.

    abstract::Significant progress has been made in systems that interpret the electrical signals of the brain in order to control an actuator. One version of these systems senses neuronal extracellular action potentials with an array of up to 100 miniature probes inserted into the cortex. The impedance of each probe is high, so en...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章,评审

    doi:10.1088/1741-2560/6/1/012001

    authors: Jochum T,Denison T,Wolf P

    更新日期:2009-02-01 00:00:00

  • Performance predictors of brain-computer interfaces in patients with amyotrophic lateral sclerosis.

    abstract:OBJECTIVE:Patients with amyotrophic lateral sclerosis (ALS) may benefit from brain-computer interfaces (BCI), but the utility of such devices likely will have to account for the functional, cognitive, and behavioral heterogeneity of this neurodegenerative disorder. APPROACH:In this study, a heterogeneous group of pati...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/13/2/026002

    authors: Geronimo A,Simmons Z,Schiff SJ

    更新日期:2016-04-01 00:00:00

  • Millimeter-scale epileptiform spike propagation patterns and their relationship to seizures.

    abstract:OBJECTIVE:Current mapping of epileptic networks in patients prior to epilepsy surgery utilizes electrode arrays with sparse spatial sampling (∼1.0 cm inter-electrode spacing). Recent research demonstrates that sub-millimeter, cortical-column-scale domains have a role in seizure generation that may be clinically signifi...

    journal_title:Journal of neural engineering

    pub_type: 杂志文章

    doi:10.1088/1741-2560/13/2/026015

    authors: Vanleer AC,Blanco JA,Wagenaar JB,Viventi J,Contreras D,Litt B

    更新日期:2016-04-01 00:00:00