A novel approach to track fetal movement using multi-sensor magnetocardiographic recordings.

Abstract:

:Changes in fetal magnetocardiographic (fMCG) signals are indicators for fetal body movement. We propose a novel approach to reliably extract fetal body movements based on the field strength of the fMCG signal independent of its frequency. After attenuating the maternal MCG, we use a Hilbert transform approach to identify the R-wave. At each R-wave, we compute the center-of-gravity (cog) of the coordinate positions of MCG sensors, each weighted by the magnitude of the R-wave amplitude recorded at the corresponding sensor. We then define actogram as the distance between the cog computed at each R-wave and the average of the cog from all the R-waves in a 3-min duration. By applying a linear de-trending approach to the actogram we identify the fetal body movement and compare this with the synchronous occurrence of the acceleration in the fetal heart rate. Finally, we apply this approach to the fMCG recorded simultaneously with ultrasound from a single subject and show its improved performance over the QRS-amplitude based approach in the visually verified movements. This technique could be applied to transform the detection of fetal body movement into an objective measure of fetal health and enhance the predictive value of prevalent clinical testing for fetal wellbeing.

journal_name

Ann Biomed Eng

authors

Govindan RB,Vairavan S,Ulusar UD,Wilson JD,McKelvey SS,Preissl H,Eswaran H

doi

10.1007/s10439-010-0231-z

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

964-72

issue

3

eissn

0090-6964

issn

1573-9686

journal_volume

39

pub_type

杂志文章
  • Estimation of Reynolds shear stresses during pulsatile flow in the region of aortic valves.

    abstract::Some investigators have attempted to estimate the Reynolds shear stress on the basis of a single component of velocity. The purpose of this investigation is to determine the validity of such estimates in a complex flow field, such as occurs in the cardiovascular system in the region of the aortic valve. Turbulent velo...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02371247

    authors: Walburn FJ,Sabbah HN,Stein PD

    更新日期:1985-01-01 00:00:00

  • Novel Balloon Surface Scanning Device for Intraoperative Breast Endomicroscopy.

    abstract::Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-015-1493-2

    authors: Zuo S,Hughes M,Yang GZ

    更新日期:2016-07-01 00:00:00

  • Analog electrical model of the coronary circulation in case of multiple revascularizations.

    abstract::In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain via preoperative measurements and well-developed collaterals might ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9500-5

    authors: Maasrani M,Verhoye JP,Corbineau H,Drochon A

    更新日期:2008-07-01 00:00:00

  • Theoretical study of the effects of vascular smooth muscle contraction on strain and stress distributions in arteries.

    abstract::To study the effects of smooth muscle contraction and relaxation on the strain and stress distribution in the vascular wall, a mathematical model was proposed. The artery was assumed to be a thick-walled orthotropic tube made of nonlinear, incompressible elastic material. Considering that the contraction of smooth mus...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.191

    authors: Rachev A,Hayashi K

    更新日期:1999-07-01 00:00:00

  • Analysis of electrically induced reentrant circuits in a sheet of myocardium.

    abstract::Understanding the complex spatiotemporal dynamics of action potential propagation in the heart during arrhythmia is exceedingly difficult. This study applies nonlinear dynamics tools to simplify this task. Using the results of a simulation of an electrical induction of reentry in a sheet of myocardium represented as a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1581289

    authors: Larson C,Dragnev L,Trayanova N

    更新日期:2003-07-01 00:00:00

  • Contraction induced muscle injury: towards personalized training and recovery programs.

    abstract::Skeletal muscles can be injured by their own contractions. Such contraction-induced injury, often accompanied by delayed onset of muscle soreness, is a leading cause of the loss of mobility in the rapidly increasing population of elderly people. Unlike other types of muscle injuries which hurt almost exclusively those...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审

    doi:10.1007/s10439-014-1173-7

    authors: Givli S

    更新日期:2015-02-01 00:00:00

  • In vitro, time-resolved PIV comparison of the effect of stent design on wall shear stress.

    abstract::The effect of stent design on wall shear stress (WSS) and oscillatory shear index (OSI) was studied in vitro using time-resolved digital particle image velocimetry (DPIV). Four drug-eluting stents [XIENCE V (Abbott Vascular), TAXUS Liberté (Boston Scientific), Endeavor (Medtronic), and Cypher (J&J Cordis)] and a bare-...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-009-9697-y

    authors: Charonko J,Karri S,Schmieg J,Prabhu S,Vlachos P

    更新日期:2009-07-01 00:00:00

  • Nonequilibrium facilitated transport of carbon dioxide in bicarbonate and bovine albumin solutions.

    abstract::The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02484468

    authors: Hoofd LJ,Tong RR,Stroeve P

    更新日期:1986-01-01 00:00:00

  • Numerical simulation of cell motion in tube flow.

    abstract::A theoretical model is presented for describing the motion of a deformable cell encapsulating a Newtonian fluid and enclosed by an elastic membrane in tube flow. In the mathematical formulation, the interior and exterior hydrodynamics are coupled with the membrane mechanics by means of surface equilibrium equations, a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-005-8975-6

    authors: Pozrikidis C

    更新日期:2005-02-01 00:00:00

  • Biased cell migration of fibroblasts exhibiting contact guidance in oriented collagen gels.

    abstract::We present here the first quantitative correlation for cell contact guidance in an oriented fibrillar network in terms of biased cell migration. The correlation is between the anisotropic cell diffusion parameter, DA = Dx/Dy, and the collagen gel birefringence, delta n, a measure of axially biased collagen fibril orie...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368241

    authors: Dickinson RB,Guido S,Tranquillo RT

    更新日期:1994-07-01 00:00:00

  • Comparison of respiratory rates derived from heart rate variability, ECG amplitude, and nasal/oral airflow.

    abstract::It would often be desirable to obtain the respiratory rate during everyday conditions without obtaining an additional respiratory trace. This study investigates the agreement between respiratory rate assessed from the electrocardiogram (ECG) and the reference respiratory rate derived from a nasal/oral airflow (AF). Na...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9580-2

    authors: Cysarz D,Zerm R,Bettermann H,Frühwirth M,Moser M,Kröz M

    更新日期:2008-12-01 00:00:00

  • The Impact of Anti-tumor Agents on ER-Positive MCF-7 and HER2-Positive SKBR-3 Breast Cancer Cells Biomechanics.

    abstract::Studying human cancer from a biomechanical perspective may contribute to pathogenesis understanding which leads to the malignancy. In this study, biomechanics of suspended and adhered breast cancer cells were investigated via the micropipette aspiration method with special emphasis on comparing the cell stiffness and ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02284-3

    authors: Metsiou DN,Siatis KE,Giannopoulou E,Papachristou DJ,Kalofonos HP,Koutras A,Athanassiou G

    更新日期:2019-08-01 00:00:00

  • Prediction of the biomechanical effects of compression therapy on deep veins using finite element modelling.

    abstract::Clinicians generally assume that Medical Compression Stockings (MCS) work by reducing vein luminal diameter and, in this way, help to prevent blood pooling. Conflicting results have been reported however in the case of lower leg deep veins which call into question this hypothesis. The purpose of this contribution is t...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-014-1121-6

    authors: Rohan PY,Badel P,Lun B,Rastel D,Avril S

    更新日期:2015-02-01 00:00:00

  • High-resolution measurement of the unsteady velocity field to evaluate blood damage induced by a mechanical heart valve.

    abstract::We investigate the potential of prosthetic heart valves to generate abnormal flow and stress patterns, which can contribute to platelet activation and lysis according to blood damage accumulation mechanisms. High-resolution velocity measurements of the unsteady flow field, obtained with a standard particle image veloc...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0329-y

    authors: Bellofiore A,Quinlan NJ

    更新日期:2011-09-01 00:00:00

  • Effect of cell-cell interactions on the observable strength of adhesion of sheets of cells.

    abstract::Previous research in cellular adhesion has focused primarily on studying isolated cells under conditions where cells do not interact with each other. However, in vivo cells form sheets where both cell-substratum and cell-cell interactions contribute to the overall adhesive behavior. Our understanding of how cell-cell ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.178

    authors: Peel MM,DiMilla PA

    更新日期:1999-03-01 00:00:00

  • Geodesic based registration of sensor data and anatomical surface image data.

    abstract::This paper presents two related methods for registering an image of an anatomical object with data from sensors arranged on the object. One method is described with reference to a test case involving a rectangular electrode plaque disposed on a heart surface, which is imaged with MRI. Data from the electrodes is fused...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-007-9350-6

    authors: Hopenfeld B,Ashikaga H,McVeigh ER

    更新日期:2007-10-01 00:00:00

  • Real-Time linux dynamic clamp: a fast and flexible way to construct virtual ion channels in living cells.

    abstract::We describe a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1408929

    authors: Dorval AD,Christini DJ,White JA

    更新日期:2001-10-01 00:00:00

  • Experimental investigation of steady flow in rigid models of abdominal aortic aneurysms.

    abstract::Abdominal aortic aneurysms occur in as much as 2-3% of the population, and their rupture produces a mortality rate of 78-94% (1), causing 15,000 deaths per year in the U.S. alone. As an investigation into the mechanical factors that lead to aneurysm rupture, flow field measurements are presented for steady flow throug...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368298

    authors: Asbury CL,Ruberti JW,Bluth EI,Peattie RA

    更新日期:1995-01-01 00:00:00

  • A computational study of the effect of false vocal folds on glottal flow and vocal fold vibration during phonation.

    abstract::The false vocal folds are believed to be components of the acoustic filter that is responsible for shaping the voice. However, the effects of false vocal folds on the vocal fold vibration and the glottal aerodynamic during phonation remain unclear. This effect has implications for computational modeling of phonation a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9630-9

    authors: Zheng X,Bielamowicz S,Luo H,Mittal R

    更新日期:2009-03-01 00:00:00

  • Cellularized microcarriers as adhesive building blocks for fabrication of tubular tissue constructs.

    abstract::To meet demands of vascular reconstruction, there is a need for prosthetic alternatives to natural blood vessels. Here we explored a new conduit fabrication approach. Macroporous, gelatin microcarriers laden with human umbilical vein endothelial cells and aortic smooth muscle cells were dispensed into tubular agarose ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-013-0883-6

    authors: Twal WO,Klatt SC,Harikrishnan K,Gerges E,Cooley MA,Trusk TC,Zhou B,Gabr MG,Shazly T,Lessner SM,Markwald RR,Argraves WS

    更新日期:2014-07-01 00:00:00

  • Constitutive modeling of pia-arachnoid complex.

    abstract::The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain during impact or inertial loading. Recent studies have revealed the complicated material behavior of the PAC. In this study, the nonlinear viscoelastic, transversely isotropic material properties of the P...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-013-0948-6

    authors: Jin X,Mao H,Yang KH,King AI

    更新日期:2014-04-01 00:00:00

  • Optimizing magnetic nanoparticle based thermal therapies within the physical limits of heating.

    abstract::Magnetic nanoparticle (mNP) based thermal therapies have demonstrated relevance in the clinic, but effective application requires an understanding of both its strengths and limitations. This study explores two critical limitations for clinical use: (1) maximizing localized mNP heating, while avoiding bulk heating due ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-012-0633-1

    authors: Etheridge ML,Bischof JC

    更新日期:2013-01-01 00:00:00

  • Image-based computational fluid dynamics modeling in realistic arterial geometries.

    abstract::Local hemodynamics are an important factor in atherosclerosis, from the development of early lesions, to the assessment of stroke risk, to determining the ultimate fate of a mature plaque. Until recently, our understanding of arterial fluid dynamics and their relationship to atherosclerosis was limited by the use of i...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审

    doi:10.1114/1.1467679

    authors: Steinman DA

    更新日期:2002-04-01 00:00:00

  • A Conceivable Mechanism Responsible for the Synergy of High and Low Voltage Irreversible Electroporation Pulses.

    abstract::Irreversible electroporation (IRE), is a new non-thermal tissue ablation technology in which brief high electric field pulses are delivered across the target tissue to induce cell death by irreversible permeabilization of the cell membrane. A deficiency of conventional IRE is that the ablation zone is relatively small...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02258-5

    authors: Lv Y,Yao C,Rubinsky B

    更新日期:2019-07-01 00:00:00

  • Inverse parameter fitting of biological tissues: a response surface approach.

    abstract::In this paper, we present the application of a semi-global inverse method for determining material parameters of biological tissues. The approach is based on the successive response surface method, and is illustrated by fitting constitutive parameters to two nonlinear anisotropic constitutive equations, one for aortic...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-005-8338-3

    authors: Einstein DR,Freed AD,Stander N,Fata B,Vesely I

    更新日期:2005-12-01 00:00:00

  • Rib Geometry Explains Variation in Dynamic Structural Response: Potential Implications for Frontal Impact Fracture Risk.

    abstract::The human thorax is commonly injured in motor vehicle crashes, and despite advancements in occupant safety rib fractures are highly prevalent. The objective of this study was to quantify the ability of gross and cross-sectional geometry, separately and in combination, to explain variation of human rib structural prope...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10439-017-1850-4

    authors: Murach MM,Kang YS,Goldman SD,Schafman MA,Schlecht SH,Moorhouse K,Bolte JH 4th,Agnew AM

    更新日期:2017-09-01 00:00:00

  • Rat aortic smooth muscle cells contract in response to serum and its components in a calcium independent manner.

    abstract::Diluted serum provides a model of interstitial fluid that can be used to study the response of smooth muscle cells (SMCs) to interstitial flow. The effect of serum and some of its components on SMC contraction (area reduction) and intracellular calcium ([Ca2+]i) response were characterized in rat aortic SMC in vitro. ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-004-7820-7

    authors: Ainslie K,Shi ZD,Garanich JS,Tarbell JM

    更新日期:2004-12-01 00:00:00

  • The effect of blood flow on the material properties of bone.

    abstract::This project was undertaken to establish if the integral circulation had any effects upon the mechanical behavior of bone. The influence of blood flow in the rabbit tibia on the strain induced at the bone surface when under load was assessed. Recordings were taken from three adult and three immature New Zealand White ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02390377

    authors: McDonald F,Pitt Ford TR

    更新日期:1994-03-01 00:00:00

  • An improved Morris Water Maze tracking algorithm for psychophysical studies.

    abstract::An algorithm to track a rat swimming in a Morris Water Maze has been developed. The system is automatically configured to any pool and relative suitable light conditions. It tracks the rat's position and head pose 10 times per second. The output data is displayed in a bitmap and also in a text file. The system was tes...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/b:abme.0000036650.32345.b6

    authors: Hval ES,Barrett SF,Wilcox M,Bailey TA

    更新日期:2004-08-01 00:00:00

  • Superparamagnetic iron oxide is suitable to label tendon stem cells and track them in vivo with MR imaging.

    abstract::Tendon stem cells (TSCs) may be used to effectively repair or regenerate injured tendons. However, the fates of TSCs once implanted in vivo remain unclear. This study was aimed to determine the feasibility of labeling TSCs with super-paramagnetic iron oxide (SPIO) nano-particles to track TSCs in vivo using MRI. Rabbit...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-013-0802-x

    authors: Yang Y,Zhang J,Qian Y,Dong S,Huang H,Boada FE,Fu FH,Wang JH

    更新日期:2013-10-01 00:00:00