Constitutive modeling of pia-arachnoid complex.

abstract：:The material properties of normal cadaveric human cartilage in the ankle mortice (tibiotalar articulation) were evaluated to determine a possible etiologic mechanism of cartilage injury of the ankle when an obvious traumatic episode is not present. Using an automated indentation apparatus and the biphasic creep indent...

journal_title：Annals of biomedical engineering

authors： Athanasiou KA,Niederauer GG,Schenck RC Jr

更新日期：1995-09-01 00:00:00

abstract：:The contractile power of the latissimus dorsi muscle (LDM) is used in skeletal muscle cardiac assist (SMCA) to augment the blood pumping ability of a failing heart. The LDM has three anatomically distinct, independently innervate segments-the transverse, oblique, and lateral. There are potential advantages to selectiv...

journal_title：Annals of biomedical engineering

authors： Thompson DR,Michele JJ,Cheever EA,George DT

更新日期：1999-01-01 00:00:00

abstract：:Analysis and classification of esophageal motility records were investigated using signal processing and fuzzy-set pattern recognition techniques. A set of parameters has been extracted from the raw records and has previously been used as characterizing features. Improvements to these procedures were obtained by extra...

journal_title：Annals of biomedical engineering

authors： Abou-Chadi FE,Ezzat FA,Sif el-Din AA

更新日期：1994-01-01 00:00:00

abstract：:The nonlinear dynamic properties of action potential encoding were studied in mechanosensory neurons innervating the slits of a slit-sense organ in the tropical wandering spider, Cupiennius salei. The organ contains two types of neurons that are morphologically similar but have different dynamic properties. Type A neu...

journal_title：Annals of biomedical engineering

authors： French AS,Sekizawa SI,Höger U,Torkkeli PH

更新日期：2001-03-01 00:00:00

abstract：:Interstitial fluid flow, critical for macromolecular transport, was recently shown to drive fibroblast differentiation and perpendicular cell and matrix alignment in 3D collagen cultures. Here we explore the mechanisms underlying this flow-induced cell and collagen alignment. Cell and matrix alignment was assessed fro...

journal_title：Annals of biomedical engineering

authors： Ng CP,Swartz MA

更新日期：2006-03-01 00:00:00

abstract：:The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

journal_title：Annals of biomedical engineering

authors： Hoofd LJ,Tong RR,Stroeve P

更新日期：1986-01-01 00:00:00

abstract：:Microencapsulation of recombinant cells is a novel promising approach to tumor therapy in which therapeutic protein is sustainable and long-term delivered by microencapsulated cells. The semi-permeable membrane of microcapsule can protect cell from host's immune rejection, increase the chemical stability of therapeuti...

journal_title：Annals of biomedical engineering

authors： Zhang Y,Wang W,Zhou J,Yu W,Zhang X,Guo X,Ma X

更新日期：2007-04-01 00:00:00

abstract：:Pathologic vascular adaptation following local injury is the primary driver for accelerated intimal hyperplasia and an occlusive phenotype. Smooth muscle cell (SMC) proliferation within the wall, and migration into the developing intima, is a major component of this remodeling response. The primary objective in the cu...

journal_title：Annals of biomedical engineering

authors： Klein B,Destephens A,Dumeny L,Hu Q,He Y,O'Malley K,Jiang Z,Tran-Son-Tay R,Berceli S

更新日期：2017-03-01 00:00:00

abstract：:The blood-brain barrier (BBB) is a major obstacle for drug delivery to the brain. To seek for in vitro BBB models that are more accessible than animals for investigating drug transport across the BBB, we compared four in vitro cultured cell models: endothelial monoculture (bEnd3 cell line), coculture of bEnd3 and prim...

journal_title：Annals of biomedical engineering

authors： Li G,Simon MJ,Cancel LM,Shi ZD,Ji X,Tarbell JM,Morrison B 3rd,Fu BM

更新日期：2010-08-01 00:00:00

abstract：:Nanomedicine (a division of nanotechnology) is an interdisciplinary research field incorporating biology, chemistry, engineering and medicine with the intention to improve disease prevention, diagnosis, and treatment. Specifically, there have been great strides made in using nanomedicine to enhance the functions of ce...

journal_title：Annals of biomedical engineering

authors： Chun YW,Webster TJ

更新日期：2009-10-01 00:00:00

abstract：:The cerebral blood flow (CBF) response to changes in perfusion pressure mediated through decreases in arterial pressure, increases in cerebrospinal fluid (CSF) pressure and increases in jugular venous pressure was studied in anesthetized dogs. A preparation was developed in which each of the three relevant pressures c...

journal_title：Annals of biomedical engineering

authors： Wagner EM,Traystman RJ

更新日期：1985-01-01 00:00:00

abstract：:We describe a model for the Compound Action Currents (CACs) and Compound Action Potentials (CAPs) produced by a peripheral nerve bundle in vitro. The Single Fiber Action Currents (SFACs) and the extracellular Single Fiber Action Potentials (SFAPs) are calculated using a generalized volume conduction model. Frequency-d...

journal_title：Annals of biomedical engineering

authors： Wijesinghe RS,Gielen FL,Wikswo JP Jr

更新日期：1991-01-01 00:00:00

abstract：:Much effort is expended in developing biomimetic scaffolds that provide the micro-architecture of native tissue with appropriate cellular niches. Such scaffolds are often seeded with progenitor cells to generate engineered replacements for diseased or damaged tissues. An alternative approach relies on biology, rather ...

journal_title：Annals of biomedical engineering

authors： Evans CH

更新日期：2015-03-01 00:00:00

abstract：:Development of increasingly complex integrated cellular systems will be a major challenge for the next decade and beyond, as we apply the knowledge gained from the sub-disciplines of regenerative medicine, synthetic biology, micro-fabrication and nanotechnology, systems biology, and developmental biology. In this pros...

journal_title：Annals of biomedical engineering

authors： Kamm RD,Bashir R

更新日期：2014-02-01 00:00:00

abstract：:The local dilation of the infrarenal abdominal aorta, termed an abdominal aortic aneurysm (AAA), is often times asymptomatic and may eventually result in rupture-an event associated with a significant mortality rate. The estimation of in-vivo stresses within AAAs has been proposed as a useful tool to predict the likel...

journal_title：Annals of biomedical engineering

authors： Vande Geest JP,Schmidt DE,Sacks MS,Vorp DA

更新日期：2008-06-01 00:00:00

abstract：:The scarcity of data available on the best approach for pulmonary fetal valve replacement or implantation necessitate an investigation on whether practices using adult transcatheter valves could be translated to fetal applications. The objective of this study is to evaluate the hemodynamic characteristics and the turb...

journal_title：Annals of biomedical engineering

authors： Hatoum H,Gooden S,Heitkemper M,Blum KM,Zakko J,Bocks M,Yi T,Wu YL,Wang Y,Breuer CK,Dasi LP

更新日期：2020-06-01 00:00:00

abstract：:A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1983-01-01 00:00:00

abstract：:An expression for centerline mean velocity distributions for circular and noncircular confined turbulent jets has been obtained by assuming self-preservation of flow downstream of the jet potential core. It was assumed that the velocity decay was not only dependent on the streamwise distance x in terms of x/d, as in t...

journal_title：Annals of biomedical engineering

authors： Liu H,Winoto SH,Shah DA

更新日期：1997-11-01 00:00:00

abstract：:New porous implant designs made possible by additive manufacturing allow for increased osseointegration, potentially improving implant performance and longevity for patients that require massive bone implants. The aim of this study was to evaluate how implantation and the strain distribution in the implant affect the ...

journal_title：Annals of biomedical engineering

authors： Cheong VS,Fromme P,Coathup MJ,Mumith A,Blunn GW

更新日期：2020-01-01 00:00:00

abstract：:In this paper, we present the application of a semi-global inverse method for determining material parameters of biological tissues. The approach is based on the successive response surface method, and is illustrated by fitting constitutive parameters to two nonlinear anisotropic constitutive equations, one for aortic...

journal_title：Annals of biomedical engineering

authors： Einstein DR,Freed AD,Stander N,Fata B,Vesely I

更新日期：2005-12-01 00:00:00

abstract：:In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

journal_title：Annals of biomedical engineering

authors： Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

更新日期：2007-01-01 00:00:00

abstract：:Three animal models were evaluated in this study involving head impacts of the rat, including the Marmarou drop-weight and two momentum-exchange techniques. In series 1, 36 Wistar rats were hit on the side of the free-moving head using Marmarou's 450 g impact mass at 4.4, 5.4, and 6.3 m/s. Head acceleration was measur...

journal_title：Annals of biomedical engineering

authors： Viano DC,Hamberger A,Bolouri H,Säljö A

更新日期：2012-01-01 00:00:00

abstract：:The measurement of CO2 volume exhaled per breath (VCO2.br) can be determined during anesthesia by the multiplication and integration of tidal flow (V) and PCO2. During side-stream capnometry, PCO2 must be advanced in time by transport delay (TD), the time to suction gas through the sampling tube. During ventilation, T...

journal_title：Annals of biomedical engineering

authors： Breen PH,Serina ER

更新日期：1997-01-01 00:00:00

abstract：:In vitro and in vivo studies were conducted on omega-3 fatty acid-derived biomaterials to determine their utility as an implantable material for adhesion prevention following soft tissue hernia repair and as a means to allow for the local delivery of antimicrobial or antibiofilm agents. Naturally derived biomaterials ...

journal_title：Annals of biomedical engineering

authors： Faucher KM,Artzi N,Beck M,Beckerman R,Moodie G,Albergo T,Conroy S,Dale A,Corbeil S,Martakos P,Edelman ER

更新日期：2016-03-01 00:00:00

abstract：:Recently, we reported that tethering and rolling of neutrophils in shear flow over a substrate of E-selectin signals activation of beta 2-integrins and firm adhesion via an intracellular signaling pathway involving phosphorylation of p38 MAP kinase. In the current study the objective was to examine the molecular mecha...

journal_title：Annals of biomedical engineering

authors： Hentzen E,McDonough D,McIntire L,Smith CW,Goldsmith HL,Simon SI

更新日期：2002-09-01 00:00:00

abstract：:We developed muscle-tendon models incorporating Hill-type structure and length-dependent coupling between activation and velocity. The models were evaluated in electrically stimulated cat soleus muscles. Dynamic model parameters were estimated by a nonlinear parameter estimation algorithm from input-output data obtain...

journal_title：Annals of biomedical engineering

authors： Shue GH,Crago PE

更新日期：1998-05-01 00:00:00

abstract：:There are recent reports of hybrid tissue-fabric materials with good performance-high biocompatibility and high mechanical strength. In this study, we demonstrate the capability of a hybrid material as a long-term filter for blood proteins. Polyester fabrics were implanted into rats to fabricate hybrid tissue-fabric m...

journal_title：Annals of biomedical engineering

authors： Inoue Y,Yokota T,Sekitani T,Kaneko A,Woo T,Kobayashi S,Shibuya T,Tanaka M,Kosukegawa H,Saito I,Isoyama T,Abe Y,Yambe T,Someya T,Sekino M

更新日期：2017-05-01 00:00:00

abstract：:Registration of bone structures is a common problem in medical research as well as in clinical applications. Intrasubject rigid 3D monomodality registration of segmented bone structures of CT images and multimodality registration of muMR and segmented muCT bone images were performed with the multiresolution intensity-...

journal_title：Annals of biomedical engineering

authors： Museyko O,Eisa F,Hess A,Schett G,Kalender WA,Engelke K

更新日期：2010-07-01 00:00:00

abstract：:Concussion tolerance and head impact exposure are highly variable among football players. Recent findings highlight that head impact data analyses need to be performed at the subject level. In this paper, we describe a method of characterizing concussion risk between individuals using a new survival analysis technique...

journal_title：Annals of biomedical engineering

authors： Rowson S,Campolettano ET,Duma SM,Stemper B,Shah A,Harezlak J,Riggen L,Mihalik JP,Brooks A,Cameron KL,Svoboda SJ,Houston MN,McAllister T,Broglio S,McCrea M

更新日期：2020-11-01 00:00:00

abstract：:Despite cellular environments having dynamic characteristics, many laboratories utilized static polyacrylamide hydrogels to study the ECM-cell relationship. To attain a more in vivo like environment, we have developed a dynamic, DNA-crosslinked hydrogel (DNA gel). Through the controlled delivery of DNA, we can tempora...

journal_title：Annals of biomedical engineering

authors： Previtera ML,Trout KL,Verma D,Chippada U,Schloss RS,Langrana NA

更新日期：2012-05-01 00:00:00