An improved Morris Water Maze tracking algorithm for psychophysical studies.

abstract：:The field of percutaneous coronary intervention has witnessed many progressions over the last few decades, more recently with the advancement of fully degradable bioabsorbable stents. Bioabsorbable materials, such as metallic alloys and aliphatic polyesters, have the potential to yield stents which provide temporary s...

journal_title：Annals of biomedical engineering

authors： Boland EL,Shine R,Kelly N,Sweeney CA,McHugh PE

更新日期：2016-02-01 00:00:00

abstract：:Integration of repair tissue is a key indicator of the long-term success of cell-based therapies for cartilage repair. The objective of this study was to compare the in vitro chondrogenic differentiation and integration of agarose hydrogels seeded with either chondrocytes or bone marrow-derived mesenchymal stem cells ...

journal_title：Annals of biomedical engineering

authors： Vinardell T,Thorpe SD,Buckley CT,Kelly DJ

更新日期：2009-12-01 00:00:00

abstract：:Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue engineering by directing chondrocytes to synthesize/degrade the extracellular matrix or promote inflammatory responses. The aim of this paper was to investigate a...

journal_title：Annals of biomedical engineering

authors： Neidlin M,Korcari A,Macheras G,Alexopoulos LG

更新日期：2018-02-01 00:00:00

abstract：:Cellular engineering applies the principles and methods of engineering to the problems of cell and molecular biology of both a basic and applied nature. As biomedical engineering has shifted from the organ and tissue level to the cellular and sub-cellular level, cellular engineering has emerged as a new area. A corner...

journal_title：Annals of biomedical engineering

authors： Nerem RM

更新日期：1991-01-01 00:00:00

abstract：:In this paper, a new method for quantification of rigidity in elbow joint of Parkinsonian patients is introduced. One of the most known syndromes in Parkinson's disease (PD) is increased passive stiffness in muscles, which leads to rigidity in joints. Clinical evaluation of stiffness in wrist and/or elbow, commonly us...

journal_title：Annals of biomedical engineering

authors： Sepehri B,Esteki A,Ebrahimi-Takamjani E,Shahidi GA,Khamseh F,Moinodin M

更新日期：2007-12-01 00:00:00

abstract：:The geometric and hemodynamic characteristics of the left and right vertebral arteries (LVA, RVA) of six healthy volunteers were investigated for the supine (S) and the prone position (P) a common sleeping posture with head rotation. MRI images were used to reconstruct the subject specific three-dimensional solid mode...

journal_title：Annals of biomedical engineering

authors： Aristokleous N,Seimenis I,Georgiou GC,Nicolaides A,Anayiotos AS

更新日期：2015-06-01 00:00:00

abstract：:Uncomplicated acute type B aortic dissections are usually treated medically, but they can become acutely complicated by rapid expansion, rupture and malperfusion syndromes and in the longer term by chronic dilatation and aortic aneurysm formation. The objective of this study is to use computational fluid dynamics reco...

journal_title：Annals of biomedical engineering

authors： Cheng Z,Wood NB,Gibbs RG,Xu XY

更新日期：2015-01-01 00:00:00

abstract：:The longitudinal assessment of joint health is a long-standing issue in the management of musculoskeletal injuries. The acoustic emissions (AEs) produced by joint articulation could serve as a biomarker for joint health assessment, but their use has been limited by a lack of mechanistic understanding of their creation...

journal_title：Annals of biomedical engineering

authors： Whittingslow DC,Jeong HK,Ganti VG,Kirkpatrick NJ,Kogler GF,Inan OT

更新日期：2020-01-01 00:00:00

abstract：:Intramuscular pressure (IMP) shows promise for estimating individual muscle tension in vivo. However, previous pressure measurements show high variability during isometric contraction and poor correlation with tension during dynamic contraction. We hypothesized that enhanced sensor anchoring/orientation would improve ...

journal_title：Annals of biomedical engineering

authors： O'Connor SM,Kaufman KR,Ward SR,Lieber RL

更新日期：2021-02-01 00:00:00

abstract：:Potential human and environmental hazards resulting from the exposure of living organisms to silver nanoparticles (Ag NPs) have been the subject of intensive discussion in the last decade. Despite the growing use of Ag NPs in biomedical applications, a quantification of the toxic effects as a function of the total sil...

journal_title：Annals of biomedical engineering

authors： Poli D,Mattei G,Ucciferri N,Ahluwalia A

更新日期：2020-04-01 00:00:00

abstract：:Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate th...

journal_title：Annals of biomedical engineering

authors： Dunkman AA,Buckley MR,Mienaltowski MJ,Adams SM,Thomas SJ,Satchell L,Kumar A,Pathmanathan L,Beason DP,Iozzo RV,Birk DE,Soslowsky LJ

更新日期：2014-03-01 00:00:00

abstract：:Overexpressed receptors, characteristic of many cancers, have been targeted by various researchers to achieve a more specific treatment for cancer. A common approach is to use the natural ligand for the overexpressed receptor as a cancer-targeting agent which can deliver a chemically or genetically conjugated toxic mo...

journal_title：Annals of biomedical engineering

authors： Yoon DJ,Liu CT,Quinlan DS,Nafisi PM,Kamei DT

更新日期：2011-04-01 00:00:00

abstract：:Modern models of cardiac membranes are often highly complex and computationally expensive, particularly when used in long simulations of spatially extended models of cardiac tissue. Therefore, there is a need for simpler membrane models that preserve the features of the complex models deemed important. This communicat...

journal_title：Annals of biomedical engineering

authors： Oliver RA,Krassowska W

更新日期：2005-07-01 00:00:00

abstract：:Numerous head injury models exist that vary in mesh density by orders of magnitude. A careful study of the mesh convergence behavior is necessary, especially in terms of strain most relevant to brain injury. To this end, as well as to investigate the effect of element integration scheme on simulated strains, we re-mes...

journal_title：Annals of biomedical engineering

authors： Zhao W,Ji S

更新日期：2019-02-01 00:00:00

abstract：:The most widely implanted prosthetic valve is the mechanical bileaflet. Recent clinical experiences suggest that some designs are more prone to thromboembolic episodes than others. This study evaluated the hinge flow and near-field forward flow of the new St. Jude Medical Regent bileaflet mechanical heart valve. Laser...

journal_title：Annals of biomedical engineering

authors： Ellis JT,Travis BR,Yoganathan AP

更新日期：2000-05-01 00:00:00

abstract：:We investigate the potential of prosthetic heart valves to generate abnormal flow and stress patterns, which can contribute to platelet activation and lysis according to blood damage accumulation mechanisms. High-resolution velocity measurements of the unsteady flow field, obtained with a standard particle image veloc...

journal_title：Annals of biomedical engineering

authors： Bellofiore A,Quinlan NJ

更新日期：2011-09-01 00:00:00

abstract：:Biologically active heart valves (tissue engineered and recellularized tissue-derived heart valves) have the potential to offer enhanced function when compared to current replacement value therapies since they can possibly remodel, and grow to meet the needs of the patient, and not require chronic medication. However,...

journal_title：Annals of biomedical engineering

authors： Hildebrand DK,Wu ZJ,Mayer JE Jr,Sacks MS

更新日期：2004-08-01 00:00:00

abstract：:Similarities between photoreceptor Kx channels and EAG and KCNQ channels suggest that the Kx channel may be related to one or both of these families of potassium channels. To provide a basis for further comparison of these channels, as well as to reveal the role of zinc (endogenously present in photoreceptors) in Kx c...

journal_title：Annals of biomedical engineering

authors： Kourennyi DE,Liu X,Barnes S

更新日期：2002-01-01 00:00:00

abstract：:Maintenance of movement accuracy relies on motor learning, by which prior errors guide future behavior. One aspect of this learning process involves the accurate generation of predictions of movement outcome. These predictions can, for example, drive anticipatory movements during a predictive-saccade task. Predictive ...

journal_title：Annals of biomedical engineering

authors： Wong AL,Shelhamer M

更新日期：2013-08-01 00:00:00

abstract：:Although it is known that long cortical bone structurally alter their area moment of inertia with age related bone loss maintaining their bending strength, the incidence of fragility fractures associated with cortical thinning still prevails. We hypothesize that cortical thinning with aging increases the local bucklin...

journal_title：Annals of biomedical engineering

authors： Lee T,Choi JB,Schafer BW,Segars WP,Eckstein F,Kuhn V,Beck TJ

更新日期：2009-09-01 00:00:00

abstract：:Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

journal_title：Annals of biomedical engineering

authors： Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

更新日期：2018-10-01 00:00:00

abstract：:The planar fibrous connective tissues of the body are composed of a dense extracellular network of collagen and elastin fibers embedded in a ground matrix, and thus can be thought of as biocomposites. Thus, the quantification of fiber architecture is an important step in developing an understanding of the mechanics of...

journal_title：Annals of biomedical engineering

authors： Sacks MS,Smith DB,Hiester ED

更新日期：1997-07-01 00:00:00

abstract：:The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

journal_title：Annals of biomedical engineering

authors： Hoofd LJ,Tong RR,Stroeve P

更新日期：1986-01-01 00:00:00

abstract：:In 12 dogs anesthetised with alpha-chloralose and urethane, and beta-adrenergic blocked with propranolol, the cervical vagi were stimulated for 60 seconds with supramaximal constant current pulses at frequencies between 2.0 and 10 Hz. The time course of the recovery of the cardiac period response, after cessation of v...

journal_title：Annals of biomedical engineering

authors： Celler BG,Lovell NH

更新日期：1991-01-01 00:00:00

abstract：:We describe a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in...

journal_title：Annals of biomedical engineering

authors： Dorval AD,Christini DJ,White JA

更新日期：2001-10-01 00:00:00

abstract：:The objective of this study was to develop a ferrocene mediated glucose biosensor for reverse iontophoresis. An amperometric ferrocene mediated glucose biosensor based on a three electrodes planar configuration was constructed using screen printing technique. Different combinations of glucose oxidase and ferrocene loa...

journal_title：Annals of biomedical engineering

authors： Ching CT,Sun TP,Huang SH,Shieh HL,Chen CY

更新日期：2010-04-01 00:00:00

abstract：:The ability to predict endothelial cell migration rates may aid in the design of biomaterials that endothelialize following implantation. However, the complexity of the signaling response to migration-promoting stimuli such as sphingosine 1-phosphate (S1P) makes such predictions quite challenging. A number of signalin...

journal_title：Annals of biomedical engineering

authors： Alford SK,Wang Y,Feng Y,Longmore GD,Elbert DL

更新日期：2010-08-01 00:00:00

abstract：:The multiphoton fluorescence recovery after photobleaching (MP-FRAP) technique has been developed to measure the three-dimensional (3D) solute diffusion within biological systems. However, current 3D MP-FRAP models are based on isotropic diffusion and spatial domain analysis. The 3D anisotropic diffusion and frequency...

journal_title：Annals of biomedical engineering

authors： Shi C,Cisewski SE,Bell PD,Yao H

更新日期：2014-03-01 00:00:00

abstract：:This work presents a novel methodology for building a three-dimensional patient-specific eyeball model suitable for performing a fully automatic finite element (FE) analysis of the corneal biomechanics. The reconstruction algorithm fits and smooths the patient's corneal surfaces obtained in clinic with corneal topogra...

journal_title：Annals of biomedical engineering

authors： Ariza-Gracia MÁ,Zurita J,Piñero DP,Calvo B,Rodríguez-Matas JF

更新日期：2016-05-01 00:00:00

abstract：:Registration of bone structures is a common problem in medical research as well as in clinical applications. Intrasubject rigid 3D monomodality registration of segmented bone structures of CT images and multimodality registration of muMR and segmented muCT bone images were performed with the multiresolution intensity-...

journal_title：Annals of biomedical engineering

authors： Museyko O,Eisa F,Hess A,Schett G,Kalender WA,Engelke K

更新日期：2010-07-01 00:00:00