Abstract：
:Recognizing the respiratory tract as a dynamic and complex ecosystem has enhanced our understanding of the pathophysiology of bovine respiratory disease (BRD). There is widespread evidence showing that disease-predisposing factors often disrupt the respiratory microbial ecosystem, provoking atypical colonization patterns and a progressive dysbiosis. The ecological factors that shape the respiratory microbiota, and the influence of these complex communities on bovine respiratory health, are a rich area for research exploration. Here, we review the current status of understanding of the bovine respiratory microbiota, the factors that influence its development and stability, its role in maintaining mucosal homeostasis, and ultimately its contribution to bovine health and disease. Finally, we explore the limitations of current research approaches to the microbiome and discuss potential directions for future research that can help us better understand the role of the respiratory microbiota in the health, welfare, and productivity of livestock.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Zeineldin M,Lowe J,Aldridge Bdoi
10.1016/j.tim.2019.04.005subject
Has Abstractpub_date
2019-09-01 00:00:00pages
753-770issue
9eissn
0966-842Xissn
1878-4380pii
S0966-842X(19)30098-8journal_volume
27pub_type
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