Abstract：
:Human T-lymphotropic virus type 1 (HTLV-1) is an exogenous retrovirus that persists lifelong in the infected host. Infection has been linked to a spectrum of diverse diseases: adult T cell leukemia, encephalomyelopathy, and predisposition to opportunistic bacterial and helminth infections. Applications of new technologies and biological concepts to the field have provided new insights into viral persistence and pathogenesis in HTLV-1 infection. Here, we summarize the emerging concepts of dynamic HTLV-1-host interactions and propose that chronic interferon (IFN) production causes tissue damage in HTLV-1-associated inflammatory diseases.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Tattermusch S,Bangham CRdoi
10.1016/j.tim.2012.07.004subject
Has Abstractpub_date
2012-10-01 00:00:00pages
494-500issue
10eissn
0966-842Xissn
1878-4380pii
S0966-842X(12)00120-5journal_volume
20pub_type
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