Demystifying Cell Cycle Arrest by HIV-1 Vif.

abstract：:Many proteins are transported to the cell surface of Saccharomyces cerevisiae and Candida albicans to be either integrated into the cell-wall structure or exported to the external medium. Secretion of many of these proteins through the classical endoplasmic reticulum-Golgi pathway is driven by a canonical N-terminal s...

journal_title：Trends in microbiology

authors： Nombela C,Gil C,Chaffin WL

更新日期：2006-01-01 00:00:00

abstract：:The rumen of sheep and cattle represents a mobile, self-sustaining fermentation system for plant material. Analysis of the rumen flora continues to provide fundamental knowledge of anaerobic microbiology and is now yielding microbial genes that have potential in biotechnology. Recent research has provided fascinating ...

journal_title：Trends in microbiology

authors： Flint HJ

更新日期：1997-12-01 00:00:00

abstract：:Although biologists have long recognized the importance of studying evolution to understand the organization of living organisms, only with the development of genomics have evolutionary studies become part of their routine toolkit. Placing genomes into an evolutionary framework has proved useful for understanding the ...

journal_title：Trends in microbiology

authors： Abby S,Daubin V

更新日期：2007-03-01 00:00:00

abstract：:The human virome is the viral component of the microbiome. Its composition, and interindividual and temporal variability are not precisely known. Its impact on human health has received less attention than that of the bacterial microbiome, but is likely to be equally important, both in homeostasis and disease. Here we...

journal_title：Trends in microbiology

authors： Lecuit M,Eloit M

更新日期：2013-10-01 00:00:00

abstract：:Key skills such as communication and critical thinking are essential for today's microbiology graduate. There are many opportunities within the undergraduate curriculum to help students to use, develop and appreciate their own unique set of skills. This article describes personal experiences of research-led teaching a...

journal_title：Trends in microbiology

authors： Verran J

更新日期：2010-02-01 00:00:00

abstract：:Recently, a new group of multicellular microorganisms was discovered, called 'cable bacteria', which are capable of generating and mediating electrical currents across centimetre-scale distances. By transporting electrons from cell to cell, cable bacteria can harvest electron donors and electron acceptors that are wid...

journal_title：Trends in microbiology

authors： Meysman FJR

更新日期：2018-05-01 00:00:00

abstract：:Many reports have documented that Staphylococcus aureus can invade host cells and persist intracellularly for various periods of time in cell culture models. However, it is not clear whether intracellular persistence of S. aureus also occurs in the course of infections in whole organisms. This is a subject of intense ...

journal_title：Trends in microbiology

authors： Garzoni C,Kelley WL

更新日期：2009-02-01 00:00:00

abstract：:The assembly of microbial communities within the gastrointestinal tract during early life plays a critical role in immune, endocrine, metabolic, and other host developmental pathways. Environmental insults during this period, such as food insecurity and infections, can disrupt this optimal microbial succession, which ...

journal_title：Trends in microbiology

authors： Robertson RC,Manges AR,Finlay BB,Prendergast AJ

更新日期：2019-02-01 00:00:00

abstract：:Plant root activities shape microbial community functioning in the soil, making the rhizosphere the epicenter of soil biogeochemical processes. With this opinion article, we argue to rethink the rhizosphere boundaries: as gases can diffuse several centimeters away from the roots into the soil, the portion of soil infl...

journal_title：Trends in microbiology

authors： de la Porte A,Schmidt R,Yergeau É,Constant P

更新日期：2020-07-01 00:00:00

abstract：:The bacterial flagellum is a complex self-assembling nanomachine that contains its own type III protein export apparatus. Upon completion of early flagellar structure, this apparatus switches substrate specificity to export late structural subunits, thereby coupling sequential flagellar gene expression with flagellar ...

journal_title：Trends in microbiology

authors： Ferris HU,Minamino T

更新日期：2006-12-01 00:00:00

abstract：:The pleiotropic post-transcriptional regulator Hfq is an RNA chaperone that facilitates pairing interactions between small regulatory RNAs (sRNAs) and their mRNA targets in several bacteria. However, this classical pattern, derived from the Escherichia coli model, is not applicable to the whole bacterial kingdom. In t...

journal_title：Trends in microbiology

authors： Jousselin A,Metzinger L,Felden B

更新日期：2009-09-01 00:00:00

abstract：:The spectacular ability of Epstein-Barr virus (EBV) to immortalize and morphologically transform human B cells in vitro to lymphoblastoid cell lines (LCLs) is central to most molecular models of viral oncogenesis. However, binding of transcription factor and oncoprotein c-Myc to the major locus control region (LCR) of...

journal_title：Trends in microbiology

authors： Niller HH,Salamon D,Banati F,Schwarzmann F,Wolf H,Minarovits J

更新日期：2004-11-01 00:00:00

abstract：:Diverse enveloped viruses enter host cells by fusing their envelopes with cell membranes. The mechanisms of merger of lipid bilayers of two membranes mediated by influenza hemagglutinin and other viral fusion proteins apparently involve local lipidic connections that evolve into a bilayer septum in which a pore forms ...

journal_title：Trends in microbiology

authors： Melikyan GB,Chernomordik LV

更新日期：1997-09-01 00:00:00

abstract：:Defensins and cathelicidins are prevalent and essential gastrointestinal cationic antimicrobial peptides (CAPs). However, these defensive peptides are not infallible because certain enteropathogens can overcome their protective function. Furthermore, impaired defensin synthesis has been linked to the occurrence of Cro...

journal_title：Trends in microbiology

authors： Peyrin-Biroulet L,Vignal C,Dessein R,Simonet M,Desreumaux P,Chamaillard M

更新日期：2006-10-01 00:00:00

abstract：:Bacteriophages are viruses of bacteria that are used for controlling bacterial food-borne pathogens and have been proposed for more extensive usage in infection control. Protists are now recognised to harbour viruses and virus-like particles. We propose that investigation of their prevalence in parasites be intensifie...

journal_title：Trends in microbiology

authors： Hyman P,Atterbury R,Barrow P

更新日期：2013-05-01 00:00:00

abstract：:Recognizing the respiratory tract as a dynamic and complex ecosystem has enhanced our understanding of the pathophysiology of bovine respiratory disease (BRD). There is widespread evidence showing that disease-predisposing factors often disrupt the respiratory microbial ecosystem, provoking atypical colonization patte...

journal_title：Trends in microbiology

authors： Zeineldin M,Lowe J,Aldridge B

更新日期：2019-09-01 00:00:00

abstract：:Improved fluorescence techniques for visualizing proteins in whole bacterial cells have resulted in recent breakthroughs in our understanding of chromosome segregation and cytokinesis in prokaryotes. The dynamics and localization of some of these proteins reveal surprisingly cytoskeletal-like behavior. ...

journal_title：Trends in microbiology

authors： Margolin W

更新日期：1998-06-01 00:00:00

abstract：:As plastic debris in the environment continues to increase, an emerging concern is the potential for microplastic to act as vectors for pathogen transport. With aquaculture the fastest growing food sector, and microplastic contamination of shellfish increasingly demonstrated, understanding any risk of pathogen transpo...

journal_title：Trends in microbiology

authors： Bowley J,Baker-Austin C,Porter A,Hartnell R,Lewis C

更新日期：2021-02-01 00:00:00

abstract：:There are an estimated 10(31) viruses on Earth, most of which are phages that infect bacteria. Metagenomic analyses have shown that environmental viral communities are incredibly diverse. There are an estimated 5000 viral genotypes in 200 liters of seawater and possibly a million different viral genotypes in one kilog...

journal_title：Trends in microbiology

authors： Breitbart M,Rohwer F

更新日期：2005-06-01 00:00:00

abstract：:The actin cytoskeleton plays a key role during the replication cycle of human immunodeficiency virus-1 (HIV-1). HIV-1 infection is affected by cellular proteins that influence the clustering of viral receptors or the subcortical actin cytoskeleton. Several of these actin-adaptor proteins are controlled by the second m...

journal_title：Trends in microbiology

authors： Rocha-Perugini V,Gordon-Alonso M,Sánchez-Madrid F

更新日期：2014-07-01 00:00:00

abstract：:DNA damage that blocks the transcription of genes is prioritized for repair by transcription-coupled DNA repair pathways. RNA polymerases stalled at DNA lesions obstruct repair enzymes, but this situation is turned to the advantage of the cell by transcription-repair coupling factors that remove the stalled RNA polyme...

journal_title：Trends in microbiology

authors： Savery NJ

更新日期：2007-07-01 00:00:00

abstract：:Most cases of candidiasis have been attributed to Candida albicans, but Candida glabrata, Candida parapsilosis and Candida tropicalis, designated as non-C. albicans Candida (NCAC), have been identified as frequent human pathogens. Moreover, Candida biofilms are an escalating clinical problem associated with significan...

journal_title：Trends in microbiology

authors： Araújo D,Henriques M,Silva S

更新日期：2017-01-01 00:00:00

abstract：:Evolution, climate change, and vaccination: in these cases and more, scientists, policymakers, and educators are confronted by organized campaigns to spread doubt, denial, and rejection of the scientific community's consensus on central scientific principles. To overcome these threats, scientists not only need to spre...

journal_title：Trends in microbiology

authors： Rosenau J

更新日期：2012-12-01 00:00:00

abstract：:Spores produced by bacilli and clostridia are surrounded by a multilayered protein shell called the coat. As the armor-like appearance of the coat suggests, this structure, along with others within the spore, confers the remarkable resistance properties that make Bacillus anthracis spores such potent biological weapon...

journal_title：Trends in microbiology

authors： Driks A

更新日期：2002-06-01 00:00:00

abstract：:Over the past two decades infections due to antibiotic-resistant bacteria have escalated world-wide, affecting patient morbidity, mortality, and health care costs. Among these bacteria, Enterococcus faecium and Enterococcus faecalis represent opportunistic nosocomial pathogens that cause difficult-to-treat infections ...

journal_title：Trends in microbiology

authors： van Harten RM,Willems RJL,Martin NI,Hendrickx APA

更新日期：2017-06-01 00:00:00

abstract：:Progress in understanding the evolution of infectious diseases has inspired proposals to manage the evolution of pathogen (including parasite) virulence. A common view is that social interventions that lower pathogen transmission will indirectly select lower virulence because of a trade-off between transmission and vi...

journal_title：Trends in microbiology

authors： Ebert D,Bull JJ

更新日期：2003-01-01 00:00:00

abstract：:DNA vaccines can induce potent humoral and cellular immune responses without any additional adjuvant. Recent studies indicate that unmethylated CpG dinucleotides within DNA vaccines are immune stimulatory and exert an essential endogenous adjuvant activity. These CpG motifs can be added deliberately to DNA or conventi...

journal_title：Trends in microbiology

authors： Krieg AM,Yi AK,Schorr J,Davis HL

更新日期：1998-01-01 00:00:00

abstract：:Vaccines preventing seasonal influenza infections save many lives every year; however, due to rapid viral evolution, they have to be updated frequently to remain effective. To identify appropriate vaccine strains, the World Health Organization (WHO) operates a global program that continually generates and interprets s...

journal_title：Trends in microbiology

authors： Klingen TR,Reimering S,Guzmán CA,McHardy AC

更新日期：2018-02-01 00:00:00

abstract：:To enhance infection, enveloped viruses exploit adhesion molecules expressed on the surface of host cells. Specifically, phosphatidylserine (PS) receptors - including members of the human T cell immunoglobulin and mucin domain (TIM)-family - have gained attention for their ability to mediate the entry of many envelope...

journal_title：Trends in microbiology

authors： Evans JP,Liu SL

更新日期：2020-03-01 00:00:00

abstract：:Oncogenic viruses have evolved direct and indirect mechanisms to overcome the tumour suppressor p53. Fortunately, tumour development is limited by the narrow cell tropisms of the viruses concerned and the host immune response. However, such viruses are helping to elucidate the p53 response pathway and may play a futur...

journal_title：Trends in microbiology

authors： Neil JC,Cameron ER,Baxter EW

更新日期：1997-03-01 00:00:00