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γδ T lymphocytes in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis.

Abstract：

:The aim of the current review is to summarize the results of studies on the role of γδ T cells in the pathogenesis of multiple sclerosis and its animal model - the experimental autoimmune encephalomyelitis. Despite the fact that numerous studies have been performed, the role of γδ T is still not fully understood. It seems that there are two distinct subpopulations - one exacerbating the disease (IL-17-producing) and the other playing a protective role (IFN-γ-secreting). Nevertheless, future studies are required for an understanding of γδ T cells role in multiple sclerosis.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Zarobkiewicz MK,Kowalska W,Roliński J,Bojarska-Junak AA

doi

10.1016/j.jneuroim.2019.02.009

subject

Has Abstract

pub_date

2019-05-15 00:00:00

pages

67-73

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(18)30535-6

journal_volume

330

pub_type

杂志文章,评审

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