Abstract:
:In the last decade, understanding of cancer initiation and progression has been given much attention with studies mainly focusing on genetic abnormalities. Importantly, cancer cells can influence their microenvironment and bi-directionally communicate with other systems such as the immune system. The nervous system plays a fundamental role in regulating immune responses to a range of disease states including cancer. Its dysfunction influences the progression of cancer. The role of the immune system in tumor progression is of relevance to the nervous system since they can bi-directionally communicate via neurotransmitters and neuropeptides, common receptors, and, cytokines. However, cross-talk between these cells is highly complex in nature, and numerous variations are possible according to the type of cancer involved. The neuro-immune interaction is essential in influencing cancer development and progression.
journal_name
J Neuroimmunoljournal_title
Journal of neuroimmunologyauthors
Kuol N,Stojanovska L,Apostolopoulos V,Nurgali Kdoi
10.1016/j.jneuroim.2017.12.016subject
Has Abstractpub_date
2018-02-15 00:00:00pages
15-23eissn
0165-5728issn
1872-8421pii
S0165-5728(17)30276-Xjournal_volume
315pub_type
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