An immunoelectron microscopical study of the expression of class II major histocompatibility complex during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice.

Abstract:

:Immunoelectron microscopical techniques have been used to study class II major histocompatibility complex (MHC) expression by cells in the spinal cords of Biozzi AB/H mice with chronic relapsing experimental allergic encephalomyelitis. Throughout the course of disease both astrocytes and endothelia failed to express significant levels of class II MHC antigens. The major central nervous system resident cell types found to express class II MHC antigens were the perivascular microglia, with infiltrating macrophages and some lymphocytes being strongly positive.

journal_name

J Neuroimmunol

authors

Butter C,O'Neill JK,Baker D,Gschmeissner SE,Turk JL

doi

10.1016/0165-5728(91)90032-3

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

37-42

issue

1

eissn

0165-5728

issn

1872-8421

pii

0165-5728(91)90032-3

journal_volume

33

pub_type

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