当前位置： SCI文献检索 > JOURNAL OF NEUROIMMUNOLOGY期刊下所有文献 > Differential binding patterns of anti-sulfatide antibodies to glial membranes.

Differential binding patterns of anti-sulfatide antibodies to glial membranes.

Abstract：

:Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may not represent the diversity of anti-sulfatide antibody binding patterns found in neuropathy patients. We sought to address this issue by generating and characterising a panel of new anti-sulfatide monoclonal antibodies. These antibodies have sulfatide reactivity distinct from existing antibodies in assays and in binding to peripheral nerve tissues and can be used to provide insights into the pathophysiological roles of anti-sulfatide antibodies in demyelinating neuropathies.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Meehan GR,McGonigal R,Cunningham ME,Wang Y,Barrie JA,Halstead SK,Gourlay D,Yao D,Willison HJ

doi

10.1016/j.jneuroim.2018.07.004

subject

Has Abstract

pub_date

2018-10-15 00:00:00

pages

28-35

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(18)30261-3

journal_volume

323

pub_type

杂志文章

相关文献

JOURNAL OF NEUROIMMUNOLOGY文献大全
  • Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis.

    abstract：:This study examined the immunoregulatory effects of anadamide, the recently identified first endogenous cannabinoid receptor ligand. Anadamide caused dose-dependent inhibition of mitogen-induced T and B lymphocyte proliferation. Its potency was 3- and 10-fold less than that of the synthetic cannabinoids delta 8-tetrah...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(94)90152-x

    authors： Schwarz H,Blanco FJ,Lotz M

    更新日期：1994-11-01 00:00:00

  • Cyclophilin inhibitor NIM811 ameliorates experimental allergic encephalomyelitis.

    abstract：:Cyclophilins have diverse functions that may affect the course of central nervous system (CNS) inflammatory disorders. Anti-inflammatory and neuroprotective mechanisms may be targeted by inhibition of cyclophilin A-dependent and cyclophilin D-dependent functions, respectively. We tested the effect of cyclophilin inhib...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2017.07.016

    authors： Huang ZL,Pandya D,Banta DK,Ansari MS,Oh U

    更新日期：2017-10-15 00:00:00

  • Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-alpha and blood-brain barrier damage.

    abstract：:The mechanism for the initiation of blood-brain barrier damage and intrathecal inflammation in multiple sclerosis (MS) is poorly understood. We have recently reported that levels of tumor necrosis factor-alpha (TNF-alpha) correlate with blood-brain barrier damage in patients with active MS. Stimulation of endothelial ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(93)90070-f

    authors： Sharief MK,Noori MA,Ciardi M,Cirelli A,Thompson EJ

    更新日期：1993-03-01 00:00:00

  • Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis.

    abstract：:Clinically isolated syndrome (CIS) is a first, usually recovering, episode of neurological disturbance(s) suggestive of multiple sclerosis (MS). CIS subjects might benefit from early disease-modifying drugs, provided that those at high risk of developing MS can be identified. Gene expression for dopaminergic receptors...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2016.07.008

    authors： Cosentino M,Zaffaroni M,Legnaro M,Bombelli R,Schembri L,Baroncini D,Bianchi A,Clerici R,Guidotti M,Banfi P,Bono G,Marino F

    更新日期：2016-09-15 00:00:00

  • Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) in humans with multiple sclerosis.

    abstract：:Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system that leads to demyelination and neurodegeneration. VIP and PACAP are structurally related neuropeptides with neuroprotective and anti-inflammatory activities. To evaluate VIP and PACAP-38 in plasma and CSF in humans in correla...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2013.08.012

    authors： Baranowska-Bik A,Kochanowski J,Uchman D,Wolinska-Witort E,Kalisz M,Martynska L,Baranowska B,Bik W

    更新日期：2013-10-15 00:00:00

  • Interleukin-6, beta-amyloid peptide and NMDA interactions in rat cortical neurons.

    abstract：:Neuronal damage in Alzheimer's disease (AD) is thought to involve direct toxicity of beta-amyloid peptide (Abeta) and excitotoxicity involving NMDA receptors (NMDARs) and altered Ca(2+) dynamics. Inflammation agents produced by microglia or astrocytes and associated with senile plaques such as the cytokine interleukin...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(03)00158-9

    authors： Qiu Z,Gruol DL

    更新日期：2003-06-01 00:00:00

  • Antigen presenting cells treated in vitro by macrophage colony-stimulating factor and autoantigen protect mice from autoimmunity.

    abstract：:Macrophage colony-stimulating factor (M-CSF) is a critical cytokine in the development of monocytic lineage and may have immunoregulatory properties. Here we show that peritoneal antigen presenting cells (APCs) treated with M-CSF produced decreased levels of proinflammatory cytokines IFN-gamma, TNF-alpha and IL-12. Th...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.09.021

    authors： Guan Y,Yu S,Zhao Z,Ciric B,Zhang GX,Rostami A

    更新日期：2007-12-01 00:00:00

  • Tumor-necrosis-factor-related apoptosis-inducing-ligand (TRAIL)-mediated death of neurons in living human brain tissue is inhibited by flupirtine-maleate.

    abstract：:Neuronal damage mediated by the TRAIL-system might be involved in the pathogenesis of neuroinflammatory diseases of the central nervous system. Here we used an investigator-independent approach to quantify TRAIL-mediated death of total CNS cells and neurons in a living human brain slice culture system, a model which i...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2005.06.027

    authors： Dörr J,Roth K,Zurbuchen U,Deisz R,Bechmann I,Lehmann TN,Meier S,Nitsch R,Zipp F

    更新日期：2005-10-01 00:00:00

  • Association to the Glypican-5 gene in multiple sclerosis.

    abstract：:Multiple sclerosis (MS) is an inflammatory, demyelinating disease affecting the central nervous system. MS-associated variants have been reported at both HLA and non-HLA loci, the latter including chromosome 13q31-32 and the Glypican-5 and Glypican-6 genes. In order to further explore the 13q31-32 region in MS, we gen...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2010.07.003

    authors： Lorentzen AR,Melum E,Ellinghaus E,Smestad C,Mero IL,Aarseth JH,Myhr KM,Celius EG,Lie BA,Karlsen TH,Franke A,Harbo HF

    更新日期：2010-09-14 00:00:00

  • Involvement of JAK/STAT signaling in the effect of cornel iridoid glycoside on experimental autoimmune encephalomyelitis amelioration in rats.

    abstract：:In the present study, we investigated the therapeutic benefit of cornel iridoid glycoside (CIG), the main component extracted from Cornus officinalis, in experimental autoimmune encephalomyelitis (EAE) rats. CIG was intragastrically administered daily after EAE initiation for 20days and reduced disease severity, incid...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.06.022

    authors： Yin L,Chen Y,Qu Z,Zhang L,Wang Q,Zhang Q,Li L

    更新日期：2014-09-15 00:00:00

  • Brain-derived gangliosides induce cell cycle arrest in a murine T cell line.

    abstract：:Gangliosides modulate various T cell effector functions through poorly defined mechanisms. To begin to understand one of their effects, the present study examined how normal brain-derived gangliosides suppress T cell proliferation using the murine T cell line, EL4, as a model. Gangliosides inhibited EL4 cell growth by...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(98)00038-1

    authors： Irani DN

    更新日期：1998-07-01 00:00:00

  • Changes in concentrations of tau-reactive antibodies are dependent on sex in Alzheimer's disease patients.

    abstract：:The presence of pre-existing natural antibodies against Alzheimer's disease (AD) pathological proteins might interfere with immune responses to therapeutic vaccination with these proteins. We aimed to compare levels of antibodies in CSF and serum: We observed higher reactivity of natural tau-reactive antibodies toward...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2018.05.004

    authors： Krestova M,Ricny J,Bartos A

    更新日期：2018-09-15 00:00:00

  • Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex.

    abstract：:Concentrations of soluble receptors for tumor necrosis factor (sTNFR-p55 and sTNFR-p75) and soluble T cell antigens CD25 and CD27 (sCD25 and sCD27) were measured in paired serum/cerebrospinal fluid (CSF) samples of 15 patients with AIDS dementia complex (ADC) and 15 HIV-infected control subjects (11 with other central...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(93)90198-8

    authors： Portegies P,Godfried MH,Hintzen RQ,Stam J,van der Poll T,Bakker M,van Deventer SJ,van Lier RA,Goudsmit J

    更新日期：1993-11-01 00:00:00

  • Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis.

    abstract：:The key role of an inhibitory receptor, Programmed Death-1, has been evaluated in 273 patients with autoimmune myasthenia gravis. At the genetic level, SNP's genotyping showed no significant association to the disease. Gene expressions in patients were not different from that in controls. Interestingly, at the cell-su...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2007.09.019

    authors： Sakthivel P,Ramanujam R,Wang XB,Pirskanen R,Lefvert AK

    更新日期：2008-01-01 00:00:00

  • Immunogenicity of synthetic peptide sequences S81 and S82 (residues 68-83 and 65-83) of bovine myelin basic protein. Time-course of antibody responses in rats and rabbits.

    abstract：:The timing and intensity of the antibody responses to the marker determinants of synthetic peptide S81 and S82 sequences of bovine myelin basic protein (MBP) (residues 68-83 and 65-83, respectively) were studied in 20 Lewis rats and 6 rabbits. All rats immunized with either peptide in CFA responded with antibody devel...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(81)90045-x

    authors： Day ED,Hashim GA,Varitek VA Jr,Paterson PY

    更新日期：1981-06-01 00:00:00

  • Studies on the intrathecal humoral immune response in canine distemper encephalitis.

    abstract：:Albumin and IgG were quantitated in paired cerebrospinal fluid (CSF) and serum samples from dogs with demyelinating canine distemper virus (CDV) infection by means of rocket immunoelectrophoresis. The IgG index as indicator for intrathecal immunoglobulin synthesis was normal in animals with non-inflammatory demyelinat...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(86)90073-1

    authors： Vandevelde M,Zurbriggen A,Steck A,Bichsel P

    更新日期：1986-03-01 00:00:00

  • MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages.

    abstract：:Toll-like receptors (TLRs) are sensors of pathogen-associated molecules that trigger inflammatory signalling in innate immune cells including macrophages. All TLRs, with the exception of TLR3, promote intracellular signalling via recruitment of the myeloid differentiation factor 88 (MyD88) adaptor, while TLR3 signals ...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2020.577217

    authors： Fitzpatrick JM,Minogue E,Curham L,Tyrrell H,Gavigan P,Hind W,Downer EJ

    更新日期：2020-06-15 00:00:00

  • Persons with secondary progressive and relapsing remitting multiple sclerosis reveal different responses of tryptophan metabolism to acute endurance exercise and training.

    abstract：:Disturbances in Tryptophan metabolism play a crucial role in multiple sclerosis (MS). Exercise is suspected to counteract the progress of MS and its side effects. Current research suggests alterations of Tryptophan metabolism in healthy individuals in response to exercise. We investigated the influence of acute aerobi...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jneuroim.2017.12.001

    authors： Bansi J,Koliamitra C,Bloch W,Joisten N,Schenk A,Watson M,Kool J,Langdon D,Dalgas U,Kesselring J,Zimmer P

    更新日期：2018-01-15 00:00:00

  • Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor.

    abstract：:Experimental autoimmune myasthenia gravis (EAMG), which to some extent represents an experimental counterpart of human myasthenia gravis, can be induced by inoculation of various animal species and strains with acetylcholine receptor (AChR). The oral administration of Torpedo AChR to Lewis rats prior to immunization w...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(93)90045-z

    authors： Wang ZY,Qiao J,Link H

    更新日期：1993-05-01 00:00:00

  • Toll-like receptor-2 deficiency is associated with enhanced brain TNF gene expression during pneumococcal meningitis.

    abstract：:TNF is a marker of disease activity in bacterial meningitis. To investigate TNF modulation by Toll-like receptor-2 (TLR2), we studied temporal and anatomical expression patterns of TLR2 and TNF in a pneumococcal meningitis model in wild type (wt) and TLR2(-/-) mice. We show by in situ hybridization that transcripts of...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2005.06.016

    authors： Letiembre M,Echchannaoui H,Ferracin F,Rivest S,Landmann R

    更新日期：2005-11-01 00:00:00

  • Peri-adolescent asthma: Acute impacts on innate immune response, corticosterone, and microglia in mice.

    abstract：:Asthma is highly comorbid with anxiety in youth. We investigated the hypothalamic-pituitary-adrenal (HPA) axis and microglia as mechanisms underlying asthma and anxiety comorbidity. We induced asthma symptoms in developing BALB/cJ mice with house dust mite (HDM) for airway inflammation and methacholine (MCH) for bronc...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2020.577450

    authors： Caulfield JI,Schopf KJ,Cavigelli SA

    更新日期：2020-11-25 00:00:00

  • Regulation of immune functions in rat splenocytes after acute and chronic in vivo treatment with CP-55,940, a synthetic cannabinoid compound.

    abstract：:Changes in mitogen-induced splenocyte proliferation and NK activity were evaluated after acute (1 h) and chronic (6 d) in vivo treatment of rats with the synthetic cannabinoid compound CP-55,940. At a dose of 0.4 mg/kg i.p. it significantly inhibited the splenocyte proliferative response to PHA and NK activity but hal...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(97)00149-5

    authors： Patrini G,Sacerdote P,Fuzio D,Manfredi B,Parolaro D

    更新日期：1997-12-01 00:00:00

  • Strain differences in sleep and other pathophysiological sequelae of influenza virus infection in naive and immunized mice.

    abstract：:To characterize behavioral and physiological alterations induced by viral respiratory infection, C57BL/6 and BALB/c strains of mice were monitored for 2 days before and 4 days after intranasal inoculation with influenza virus. Both strains developed hypothermia, decrease locomotor activity, and decreased delta-wave am...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/0165-5728(94)00193-r

    authors： Toth LA,Rehg JE,Webster RG

    更新日期：1995-04-01 00:00:00

  • TRPV1 polymorphisms and risk of interferon β-induced flu-like syndrome in patients with relapsing-remitting multiple sclerosis.

    abstract：:Interferon-β (IFN-β) is often discontinued in RRMS patients due to its most common side effect, the flu-like syndrome (FLS). The mechanisms underlying IFN β-induced FLS symptoms are still unclear. The endocannabinoid system (ECS) is a key regulator of pain and inflammation. Thus we tested the hypothesis that the ECS c...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2017.02.007

    authors： Buttari F,Zagaglia S,Marciano L,Albanese M,Landi D,Nicoletti CG,Mercuri NB,Silvestrini M,Provinciali L,Marfia GA,Mori F,Centonze D

    更新日期：2017-04-15 00:00:00

  • Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy.

    abstract：:Traumatic optic neuropathy (TON) is associated with apoptosis of retinal ganglion cells. Local productions of reactive oxygen species and inflammatory mediators from activated microglial cells have been hypothesized to underlie apoptotic processes. We previously demonstrated that the anti-inflammatory effect of adenos...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.10.006

    authors： Ahmad S,Elsherbiny NM,Bhatia K,Elsherbini AM,Fulzele S,Liou GI

    更新日期：2014-12-15 00:00:00

  • Gene expression changes in chronic inflammatory demyelinating polyneuropathy skin biopsies.

    abstract：:Chronic-inflammatory demyelinating polyneuropathy (CIDP) is an immune-mediated disease with no known biomarkers for diagnosing the disease or assessing its prognosis. We performed transcriptional profiling microarray analysis on skin punch biopsies from 20 CIDP patients and 17 healthy controls to identify disease-asso...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.03.002

    authors： Puttini S,Panaite PA,Mermod N,Renaud S,Steck AJ,Kuntzer T

    更新日期：2014-05-15 00:00:00

  • Dynamic changes in meningeal inflammation correspond to clinical exacerbations in a murine model of relapsing-remitting multiple sclerosis.

    abstract：:Inflammation in the meninges, tissues surrounding the brain and spinal cord that enclose the cerebrospinal fluid, closely parallels clinical exacerbations in relapsing-remitting experimental autoimmune encephalomyelitis (EAE). In preclinical disease, an influx of innate immune cells precedes loss of blood brain barrie...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2014.12.009

    authors： Walker-Caulfield ME,Hatfield JK,Brown MA

    更新日期：2015-01-15 00:00:00

  • TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents.

    abstract：:The aggregation and deposition of transactivation response DNA-binding protein 43 (TDP-43) in neurons and astrocytes is characteristic in a number of neurodegenerative diseases including Alzheimer's disease, frontotemporal lobar degeneration, and amyotrophic lateral sclerosis. Nevertheless, the exact role of TDP-43 in...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2017.10.011

    authors： Huang CY,Lee YC,Li PC,Liliang PC,Lu K,Wang KW,Chang LC,Shiu LY,Chen MF,Sun YT,Wang HK

    更新日期：2017-12-15 00:00:00

  • Induction of TRAIL-mediated glioma cell death by human T cells.

    abstract：:Among the death ligands of the tumor necrosis factor/nerve growth factor (TNF/NGF) superfamily, TNF-related apoptosis-inducing ligand (TRAIL) is considered to play a unique role due to its binding to both apoptosis-inducing and -blocking membranous receptors, apoptosis-independent effects and distinct species differen...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/s0165-5728(01)00450-7

    authors： Dörr J,Waiczies S,Wendling U,Seeger B,Zipp F

    更新日期：2002-01-01 00:00:00

  • HLA-DQA1*03:02/DQB1*03:03:02 is strongly associated with susceptibility to childhood-onset ocular myasthenia gravis in Southern Han Chinese.

    abstract：OBJECTIVE:Our aim was to investigate the correlation between onset age, clinical features and HLA-DQA1/DQB1 genetic variability in myasthenia gravis (MG) patients in Southern Han Chinese. METHODS:205 MG patients and 100 controls were genotyped for HLA-DQA1 and -DQB1 using sequence-based typing (SBT) and analyzed for h...

    journal_title：Journal of neuroimmunology

    pub_type： 杂志文章

    doi：10.1016/j.jneuroim.2012.03.018

    authors： Zhu WH,Lu JH,Lin J,Xi JY,Lu J,Luo SS,Qiao K,Xiao BG,Lu CZ,Zhao CB

    更新日期：2012-06-15 00:00:00