Phytoestrogens inhibit key-enzymes linked to obesity, type 2 diabetes and liver-kidney toxicity in high fructose-fat diet in mice.

abstract：:Objective: The pattern of urinary excretion of total sulphated glycosaminoglycans (GAGs) and their particular types: chondroitin sulphate/dermatan sulphate (CS/DS) and heparan sulphate (HS) was analysed in obese patients with type 2 diabetes mellitus (T2DM) treated with metformin in monotherapy for the period of six m...

journal_title：Archives of physiology and biochemistry

authors： Jura-Półtorak A,Olczyk P,Chałas-Lipka A,Komosińska-Vassev K,Kuźnik-Trocha K,Winsz-Szczotka K,Ivanova D,Kiselova-Kaneva Y,Krysik K,Telega A,Olczyk K

更新日期：2019-12-09 00:00:00

abstract：:Diabetes mellitus, especially when complicated with decline of renal function due to diabetic nephropathy (DN), is associated with accumulation of advanced glycation end products (AGEs) exerting their adverse effects via receptor of AGE (RAGE). Soluble RAGE (sRAGE) is a truncated form of RAGE functioning as an inhibit...

journal_title：Archives of physiology and biochemistry

authors： Kanková K,Kalousová M,Hertlová M,Krusová D,Olsovský J,Zima T

更新日期：2008-04-01 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the devastating complications in diabetes mellitus (DM). Glucagon-like peptide-1 (GLP-1) is one of the incretins secreted from L cells in the intestine. Crocin (a carotenoid component of saffron) has antioxidants properties. We investigated the renal effects of Exendin-4 as a GLP-1 ...

journal_title：Archives of physiology and biochemistry

authors： Amin SN,El-Gamal EM,Rashed LA,Kamar SS,Haroun MA

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:NAFLD patients have higher risk of atherosclerosis cardiovascular disease (ASCVD). apo B/apoA-I ratio and atherogenic index of plasma (AIP) have been suggested as biomarker for ASCVD. METHODS:apo A-I, apoB, aryl esterase (ARE) and paraoxonase (PON) activities and carotid intima media thickness (cIMT) were d...

journal_title：Archives of physiology and biochemistry

authors： Fadaei R,Meshkani R,Poustchi H,Fallah S,Moradi N,Panahi G,Merat S,Golmohammadi T

更新日期：2019-02-01 00:00:00

abstract：:Recent studies reported good intra-individual reproducibility, but great inter-individual variation in a sample of elite athletes, in time to exhaustion (tlim) at the maximal aerobic speed (MAS: the lowest speed that elicits VO2max in an incremental treadmill test). The purpose of the present study was, on the one han...

journal_title：Archives of physiology and biochemistry

authors： Gazeau F,Koralsztein JP,Billat V

更新日期：1997-10-01 00:00:00

abstract：:The early and late effects of alloxan-diabetes and insulin treatment on kinetic properties of mitochondrial FoF1 ATPase were examined. Diabetic state resulted in significant decrease in the activity while insulin treatment caused hyper-stimulation. In control animals the enzyme activity resolved in three kinetic compo...

journal_title：Archives of physiology and biochemistry

authors： Patel SP,Katyare SS

更新日期：2006-07-01 00:00:00

abstract：:Arecoline is known to cause endocrine dysfunction. In the current article role of arecoline on pineal-testis activity was investigated in hypothyroid rats induced by propylthiouracil (PTU). PTU treatment caused thyroid dysfunction ultrastructurally with a fall in T3 and T4 levels followed by a rise of thyroid stimulat...

journal_title：Archives of physiology and biochemistry

authors： Saha I,Chakraborty SB,Chatterjee A,Pradhan D,Chatterji U,Maiti BR

更新日期：2020-02-01 00:00:00

abstract：CONTEXT:The views of type 2 diabetes (T2DM) patients have not been considered in the debate on the role of self-monitoring of blood glucose (SMBG) in the management of T2DM. OBJECTIVE:To assess the views of T2DM patients on SMBG. METHODS:Two previously trained research assistants used a structured pre-tested question...

journal_title：Archives of physiology and biochemistry

authors： Ezenwaka CE,Olukoga A,Onuoha P,Worrell R,Skinner T,Mayers H,Martin E,Phillip C

更新日期：2012-02-01 00:00:00

abstract：:Context: The anti-diabetic medicine metformin has been reported as an anti-ageing drug candidate as it mimics the benefits of caloric restriction and reduces ageing-related oxidative stress in various experimental organisms. Objective: We investigated the possible anti-oxidative role of metformin against rotenone-indu...

journal_title：Archives of physiology and biochemistry

authors： Tripathi SS,Singh AK,Akhtar F,Chaudhary A,Rizvi SI

更新日期：2019-06-01 00:00:00

abstract：:Mammalian gonadotropin-releasing hormone (GnRH I) is a hypothalamic decapeptide that governs gonadotropin secretion through interaction with its seven transmembrane (7TM), G protein-coupled receptor (GPCR) expressed by anterior pituitary cells. A second decapeptide, GnRH II, originally discovered in the chicken hypoth...

journal_title：Archives of physiology and biochemistry

authors： Neill JD

更新日期：2002-04-01 00:00:00

abstract：:Objectives: The main aim of this study was to investigate the effects of irisin on asprosin, leptin, glucose levels and lipid profile in healthy and obese male and female rats.Methods: Irisin was subcutaneously administered with osmotic minipumps at the dose of 100 ng/kg/day for 28 days and then, the serum levels of a...

journal_title：Archives of physiology and biochemistry

authors： Ozcan S,Ulker N,Bulmus O,Yardimci A,Ozcan M,Canpolat S

更新日期：2020-02-06 00:00:00

abstract：:Autophagy is an important life phenomenon in eukaryotic cells. Its main role is to remove and degrade its damaged organelles and excess biological macromolecules, and use degradation products to provide energy and rebuild the cell structure, playing an important role in maintaining cell homeostasis and cell life activ...

journal_title：Archives of physiology and biochemistry

authors： Xu HM,Hu F

更新日期：2019-10-09 00:00:00

abstract：:Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

journal_title：Archives of physiology and biochemistry

authors： Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

更新日期：2019-09-13 00:00:00

abstract：:Dopamine (DA) is thought to modulate the transduction of the hypoxic stimulus by the glomus cell in the carotid body (CB). The hypothesis tested here is that presynaptic DA D2 receptors (D2's) located on the type 1 cell function as autoreceptors to control DA release and/or synthesis. The aim of the study was to compa...

journal_title：Archives of physiology and biochemistry

authors： Basson H,Bairam A,Cottet-Emard JM,Pequignot JM,Marchal F

更新日期：1997-02-01 00:00:00

abstract：:Type 2 Diabetes mellitus (T2D) is the most common endocrine disorder associated to metabolic syndrome (MS) and occurs when insulin secretion can no compensate peripheral insulin resistance. Among peripheral tissues, the liver controls glucose homeostasis due to its ability to consume and produce glucose. The molecular...

journal_title：Archives of physiology and biochemistry

authors： Valverde AM,González-Rodríguez A

更新日期：2011-07-01 00:00:00

abstract：:Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in...

journal_title：Archives of physiology and biochemistry

authors： Hosseini SA,Hamzavi K,Safarzadeh H,Salehi O

更新日期：2020-10-05 00:00:00

abstract：:The influence of ageing on the capacity to increase muscle oxygen delivery during exercise is unclear. This was investigated by comparing the evolution of Near InfraRed Spectroscopy (NIRS) in 10 old (67 +/- 5 years, Old group) and 13 young subjects (27 +/- 4 years, Young group), during a progressive maximal exercise. ...

journal_title：Archives of physiology and biochemistry

authors： Costes F,Denis C,Roche F,Prieur F,Enjolras F,Barthélémy JC

更新日期：1999-04-01 00:00:00

abstract：:Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...

journal_title：Archives of physiology and biochemistry

authors： Tortosa F,Dotta F

更新日期：2013-10-01 00:00:00

abstract：:Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. In recent years, considerable interest has been focused on curcumin due to its use to treat a wide variety of disorders without any side effects. It is one of the major curcuminoids of turmeric,...

journal_title：Archives of physiology and biochemistry

authors： Pari L,Tewas D,Eckel J

更新日期：2008-04-01 00:00:00

abstract：:Context: Recent surveys have shown an association between proprotein convertase subtilisin/kexin type 9 (PCSK9) and oxidative stress.Objective: In this investigation, the effect of evolocumab an anti-PCSK9 antibody was assessed against oxidative damage caused by hydrogen peroxide (H2O2) in human umbilical vein endothe...

journal_title：Archives of physiology and biochemistry

authors： Safaeian L,Mirian M,Bahrizadeh S

更新日期：2020-07-03 00:00:00

abstract：:From the first report that bone marrow cells (BMC) have stem cells characteristics, several studies have debated the possibility of intervening in myocardial remodeling after injury, for example myocardial infarction, by using BMC. The goal of this paper is to review the concept of whether the demethylating agent 5-az...

journal_title：Archives of physiology and biochemistry

authors： Burlacu A

更新日期：2006-10-01 00:00:00

abstract：:The mechanism underlying the increased rate of endogenous glucose production from the liver during exercise remains unknown. The cytokine interleukin-6 (IL-6) is known to be released during exercise and is thought that either IL-6 directly or via a "contraction factor" stimulates the release of stored glucose from the...

journal_title：Archives of physiology and biochemistry

authors： Dent JR,Chowdhury MK,Tchijov S,Dulson D,Smith G

更新日期：2016-01-01 00:00:00

abstract：:The effect of underfeeding over glucose metabolism in uteri isolated from ovariectomized and non-ovariectomized rats subjected to a restricted diet for 25 days (50% of the normal food intake), was studied. Underfeeding decreases (14)CO(2) formation from U(14) C-glucose in intact animal uteri. While in ovariectomized r...

journal_title：Archives of physiology and biochemistry

authors： Campos ML,Casalino-Matsuda SM,Linares JA,Goldraij A

更新日期：2000-12-01 00:00:00

abstract：:Background: We aim to identify and analyze the expression of dyregulated RNAs in colorectal cancer (CRC). Methods: We selected a panel of RNAs specific to CRC composed of Nucleosome Assembly Protein 1 Like 2 (NAP1L2) mRNA, LNCRNA SNHG14 small nucleolar RNA host gene 14 (LNCRNA SNHG14) and homo sapiens microRNA-3940-5p...

journal_title：Archives of physiology and biochemistry

authors： Matboli M,Shafei AE,Ali MA,El-Din Ahmed TS,Naser M,Abdel-Rahman T,Anber N,Ali M

更新日期：2019-08-09 00:00:00

abstract：:Circadian rhythms affect a variety of physiological processes. Disruption of circadian rhythms causes many diseases, most of which are associated with inflammation. Disruption of circadian rhythms has a detrimental impact on the function of immune system. It is common to find that circulatory LPS are increased. LPS in...

journal_title：Archives of physiology and biochemistry

authors： Luo X,Yang X,Yang Y,Li H,Cui H,Cao X

更新日期：2020-07-01 00:00:00

abstract：:The present study aimed to evaluate the relationship between exercise and both l-tyrosine and oxidative stress using thiol/disulphide homeostasis via a novel biomarker in rats. Following the completion of the exercise and l-tyrosine protocol, serum total thiol, native thiol, and disulphide concentrations were determin...

journal_title：Archives of physiology and biochemistry

authors： Kayacan Y,Yazar H,Kisa EC,Ghojebeigloo BE

更新日期：2018-07-01 00:00:00

abstract：:Aberrant expression of miRNAs has a link with tumorgenesis and their deregulation is reported in biological fluids of cancer patients. Authors aimed to investigate the diagnostic role of miRNA-17-5p, miR-155 and miRNA-222 in serum samples from breast cancer patients (n = 80), benign breast patients (n = 40) and health...

journal_title：Archives of physiology and biochemistry

authors： Swellam M,Zahran RFK,Abo El-Sadat Taha H,El-Khazragy N,Abdel-Malak C

更新日期：2019-12-01 00:00:00

abstract：:This study aimed to investigate the roles of RPSAP52 in renal failure. Our results showed that RPSAP52 was upregulated in plasma of renal failure patients in comparison to healthy controls. Dual luciferase reporter assay showed that RPSAP52 could interact with miR-423-5p, while overexpression of RPSAP52 and miR-423-5p...

journal_title：Archives of physiology and biochemistry

authors： Chen J,Zheng Y,Li L

更新日期：2020-04-17 00:00:00

abstract：:An important role in the regulation of glucose homeostasis is played by incretins, which are gut-derived hormones released in response to nutrient ingestion. In humans, the major incretin hormones are glucagon-like peptide (GLP)-1 and glucose-dependent insulinotropic polypeptide (GIP), and together they fully account ...

journal_title：Archives of physiology and biochemistry

authors： Opinto G,Natalicchio A,Marchetti P

更新日期：2013-10-01 00:00:00

abstract：:Investigations were undertaken to obtain information on the mechanism by which orally administered spermine induces postnatal maturation in the rat intestine. Suckling rats ingested one dose of spermine (8 mumol) then were sacrificed at different intervals. -A. Proximal and distal parts of the intestine were homogenis...

journal_title：Archives of physiology and biochemistry

authors： Wéry I,Deloyer P,Dandrifosse G

更新日期：1996-01-01 00:00:00