The role of autophagy and mitophagy in cancers.

abstract：:The actions of the insulin-like growth factor (IGF)-system are controlled by six IGF-binding proteins (IGFBPs). The IGFBPs are thought to affect local effects of IGF-I and IGF-II due to higher affinity if compared to IGF-I receptors and due to cell-type specific IGFBP expression patterns. It was found in IGFBP knockou...

journal_title：Archives of physiology and biochemistry

authors： Hoeflich A,Götz W,Lichanska AM,Bielohuby M,Tönshoff B,Kiepe D

更新日期：2007-06-01 00:00:00

abstract：:From the first report that bone marrow cells (BMC) have stem cells characteristics, several studies have debated the possibility of intervening in myocardial remodeling after injury, for example myocardial infarction, by using BMC. The goal of this paper is to review the concept of whether the demethylating agent 5-az...

journal_title：Archives of physiology and biochemistry

authors： Burlacu A

更新日期：2006-10-01 00:00:00

abstract：:In the last decade proteomics has made great progress reaching throughput and comprehensiveness comparable to genomics technologies. Mass spectrometry plays a key role in proteomics and has become an indispensable method for molecular and cellular biology because many cellular changes in response to internal or extern...

journal_title：Archives of physiology and biochemistry

authors： Fröbel J,Lehr S,Haas R,Czibere A

更新日期：2009-12-01 00:00:00

abstract：:Isolation of glycosylated 26 kDa rat prolactin and subsequent proper carbohydrate characterization has so far not been reported. In the present work the hormone isoform was isolated to 95% homogeneity by preparative electrophoretic separation on Mini Prep Cell of rat pituitary homogenate. The isoform was then investig...

journal_title：Archives of physiology and biochemistry

authors： Bollengier F,Mahler A,Braet C,Claeyssens M,Vanhaelst L

更新日期：2001-04-01 00:00:00

abstract：:Glycogen synthesis increases after muscle contraction and during insulin stimulation, and insulin-stimulated glycogen synthesis is enhanced after contraction. We hypothesized that the initial glycogen content influences the magnitude of additive effect of contraction on insulin-stimulated glycogen synthesis. Contracti...

journal_title：Archives of physiology and biochemistry

authors： Lai YC,Stuenaes JT,Kuo CH,Jensen J

更新日期：2010-07-01 00:00:00

abstract：:A-4166, a phenylalanine derivative, is a hypoglycemic agent, which has been shown to improve blood glucose levels mainly due to the rapid and short term stimulation of insulin release. Nevertheless, a possible extrapancreatic action of A-4166 has not yet been investigated. Therefore, insulin action (euglycemic hyperin...

journal_title：Archives of physiology and biochemistry

authors： Klimes I,Mitková A,Gasperíková D,Ukropec J,Líska B,Bohov P,Stanek J,Seböková E

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects. METHODS:A retrospective case control study comprised of 1794 patient (740 males and 1054 females). RESULTS:The correlation was found for lipid profile with ...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Maharaj N,Fatt LA,Legall G

更新日期：2012-02-01 00:00:00

abstract：AIM:A high-fat diet (HFD) can lead to obesity and related metabolic disorders. This study evaluated the preventive efficacy of myricetin derivative-rich fraction (MD) from Syzygium malaccense leaf extract against HFD-induced obesity, hyperglycaemia, and oxidative stress in C57BL/6J mice. METHODS:HFD-fed mice were admi...

journal_title：Archives of physiology and biochemistry

authors： Nallappan D,Ong KC,Palanisamy UD,Chua KH,Kuppusamy UR

更新日期：2020-08-19 00:00:00

abstract：:Pyruvate carboxylase (PC) has been quantified in rat liver and kidney cortex under experimental conditions that modify the gluconeogenic response in both organs: fasting, carbon tetrachloride-induced liver degeneration and alloxan-induced diabetes. Enzymatic activity has been assayed by a 14CO2-fixation method. The am...

journal_title：Archives of physiology and biochemistry

authors： Salto R,Sola M,Oliver FJ,Vargas AM

更新日期：1996-12-01 00:00:00

abstract：:The consumption of high calorie-content diets is the first cause of obesity, probably the main health issue worldwide; however, the experimental evidences for evaluating the differential metabolic modifications of high-sucrose or high-fat diets are scare. We evaluated the metabolic outcomes of the obesity induced by t...

journal_title：Archives of physiology and biochemistry

authors： Gómez-Crisóstomo NP,De la Cruz-Hernández EN,Méndez Méndez ER,Hernández-Landero MF,Camacho Liévano JU,Martínez-Abundis E

更新日期：2020-07-01 00:00:00

abstract：:Background: The microRNAs have come up as crucial mediators of energy balance and metabolic control. CD36 is potential biomarker of obesity and metabolic syndrome. This study investigates the concentration of miR-146a and miR-21 and CD 36 in blood samples of obese and healthy young participants. We assessed the associ...

journal_title：Archives of physiology and biochemistry

authors： Benbaibeche H,Hichami A,Oudjit B,Haffaf EM,Kacimi G,Koceïr EA,Khan NA

更新日期：2020-06-13 00:00:00

abstract：:Investigations were undertaken to obtain information on the mechanism by which orally administered spermine induces postnatal maturation in the rat intestine. Suckling rats ingested one dose of spermine (8 mumol) then were sacrificed at different intervals. -A. Proximal and distal parts of the intestine were homogenis...

journal_title：Archives of physiology and biochemistry

authors： Wéry I,Deloyer P,Dandrifosse G

更新日期：1996-01-01 00:00:00

abstract：:In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to that occurring spontaneously. Eight mumol spermine were administered orally once a day, for one or three days, to su...

journal_title：Archives of physiology and biochemistry

authors： Peulen O,Pirlet C,Klimek M,Goffinet G,Dandrifosse G

更新日期：1998-02-01 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the devastating complications in diabetes mellitus (DM). Glucagon-like peptide-1 (GLP-1) is one of the incretins secreted from L cells in the intestine. Crocin (a carotenoid component of saffron) has antioxidants properties. We investigated the renal effects of Exendin-4 as a GLP-1 ...

journal_title：Archives of physiology and biochemistry

authors： Amin SN,El-Gamal EM,Rashed LA,Kamar SS,Haroun MA

更新日期：2020-12-07 00:00:00

abstract：:Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

journal_title：Archives of physiology and biochemistry

authors： Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

更新日期：2019-09-13 00:00:00

abstract：CONTEXT:Essential oils from Pinus species have been reported to have various therapeutic properties. OBJECTIVE:This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. MATERIAL AND METHODS:Th...

journal_title：Archives of physiology and biochemistry

authors： Bouzenna H,Hfaiedh N,Bouaziz M,Giroux-Metges MA,Elfeki A,Talarmin H

更新日期：2017-12-01 00:00:00

abstract：:This study investigated the expression and underlying molecular mechanism of CPSF1 in diabetic retinopathy. Streptozotocin (STZ)-induced Sprague-Dawley (SD) rats were employed as a diabetic model, and high-glucose (HG)-induced human retinal vascular endothelial cells （HRVECs）were used as an in vitro experimental model...

journal_title：Archives of physiology and biochemistry

authors： Zhang J,Zhang X,Zou Y,Han F

更新日期：2020-02-12 00:00:00

abstract：OBJECTIVES:Examine the diagnostic role of serum exosomal RAB27A mRNA in lung cancer and evaluate the relation of LncRNAs to lung cancer in association to RAB27A mRNA in Egyptian population. METHODS:Exosomal RNA-based biomarkers RAB27A mRNA and Lnc-RNA-RP11-510M2.10 were selected based on bioinformatic methods, followe...

journal_title：Archives of physiology and biochemistry

authors： Mohamed Gamal El-Din G,Ibrahim FK,Shehata HH,Osman NM,Abdel-Rahman OM,Ali M

更新日期：2020-07-13 00:00:00

abstract：:The mechanism underlying the increased rate of endogenous glucose production from the liver during exercise remains unknown. The cytokine interleukin-6 (IL-6) is known to be released during exercise and is thought that either IL-6 directly or via a "contraction factor" stimulates the release of stored glucose from the...

journal_title：Archives of physiology and biochemistry

authors： Dent JR,Chowdhury MK,Tchijov S,Dulson D,Smith G

更新日期：2016-01-01 00:00:00

abstract：:Objectives: The main aim of this study was to investigate the effects of irisin on asprosin, leptin, glucose levels and lipid profile in healthy and obese male and female rats.Methods: Irisin was subcutaneously administered with osmotic minipumps at the dose of 100 ng/kg/day for 28 days and then, the serum levels of a...

journal_title：Archives of physiology and biochemistry

authors： Ozcan S,Ulker N,Bulmus O,Yardimci A,Ozcan M,Canpolat S

更新日期：2020-02-06 00:00:00

abstract：:Context: Small peptides as multifunctional biomolecules can prevent the metabolic disorders such as diabetes. Objective: The purpose of this study was to investigate the effects of small peptides on the enzymes and histopathology of the liver in mice exposed to diabetes. Methods: Di- and tri-peptides containing prolin...

journal_title：Archives of physiology and biochemistry

authors： Mesgari-Abbasi M,Valizadeh H,Mirzakhani N,Vahdatpour T

更新日期：2019-09-09 00:00:00

abstract：:This study was to investigate whether epidermal growth factor (EGF) may induce any long-term effect on pancreatic exocrine function in vivo as well to evaluate the chronic effects of EGF on pancreatic growth in rats. Rats were treated with EGF (10 micrograms/kg) for 5 or 7 days. EGF infused intravenously (2 micrograms...

journal_title：Archives of physiology and biochemistry

authors： Lajas AI,Pozo MJ,Salido GM,Singh J,Pariente JA

更新日期：1996-01-01 00:00:00

abstract：:Context: Exposure to Electomagnetic radiation fields of cell phones causes thyroid dysfunction and a previous study revealed that nesfatin-1 may affect functions of the thyroid gland.Objective: To study the role of nesfatin-1 on functions of rat's thyroid gland exposed to EMRF.Materials and methods: Thirty adult male ...

journal_title：Archives of physiology and biochemistry

authors： Hussien NI,Mousa AM,Shoman AA

更新日期：2020-06-17 00:00:00

abstract：CONTEXT:The views of type 2 diabetes (T2DM) patients have not been considered in the debate on the role of self-monitoring of blood glucose (SMBG) in the management of T2DM. OBJECTIVE:To assess the views of T2DM patients on SMBG. METHODS:Two previously trained research assistants used a structured pre-tested question...

journal_title：Archives of physiology and biochemistry

authors： Ezenwaka CE,Olukoga A,Onuoha P,Worrell R,Skinner T,Mayers H,Martin E,Phillip C

更新日期：2012-02-01 00:00:00

abstract：:It is known that oxidative stress plays an important role in the chronic complications of diabetes. Lipid peroxidation is one of the consequences of oxidative stress. Erythrocyte deformability abilities are reduced as a result of lipid peroxidation. Conversely, a decrease nitric oxide (NO) production seems to be respo...

journal_title：Archives of physiology and biochemistry

authors： Yapislar H,Aydogan S

更新日期：2012-12-01 00:00:00

abstract：:Arecoline is known to cause endocrine dysfunction. In the current article role of arecoline on pineal-testis activity was investigated in hypothyroid rats induced by propylthiouracil (PTU). PTU treatment caused thyroid dysfunction ultrastructurally with a fall in T3 and T4 levels followed by a rise of thyroid stimulat...

journal_title：Archives of physiology and biochemistry

authors： Saha I,Chakraborty SB,Chatterjee A,Pradhan D,Chatterji U,Maiti BR

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND AIM:Tobago and Trinidad are two Caribbean islands with distinct genetic background and lifestyles; while Tobago is serene and a tourist centre, Trinidad is characterized by a hustling and bustling lifestyle. The study was aimed at determining and comparing the prevalence of the metabolic syndrome (MetS) ...

journal_title：Archives of physiology and biochemistry

authors： Ezenwaka CE,Nwagbara E,Seales D,Okali F,Hussaini S,Raja B,Wheeler V,Sell H,Avci H,Eckel J

更新日期：2007-10-01 00:00:00

abstract：:Background: Oxidative stress, has been shown to play an important role in the pathophysiology of cardiac remodelling and heart failure. The aim of study is effect of arginine vasopressin (AVP) on apoptosis of cardiomyocyte via its receptors.Materials and methods: The cell viability effect of AVP in H9C2 cardiomyocytes...

journal_title：Archives of physiology and biochemistry

authors： Ghorbanzadeh V,Jafarpour A,Pirnia A,Pajouhi N,Khaksarian M,Veiskarami S,Nazari A

更新日期：2020-03-06 00:00:00

abstract：:The authors conducted this meta-analysis to robustly estimate relationships between polymorphisms in VDR gene and the risk of osteoporosis by integrating the results of previous works. Medline, Embase, Wanfang, VIP and CNKI were searched thoroughly for eligible studies, and 73 genetic association studies were finally ...

journal_title：Archives of physiology and biochemistry

authors： Jiang LL,Zhang C,Zhang Y,Ma F,Guan Y

更新日期：2020-08-06 00:00:00

abstract：:Dopamine (DA) is thought to modulate the transduction of the hypoxic stimulus by the glomus cell in the carotid body (CB). The hypothesis tested here is that presynaptic DA D2 receptors (D2's) located on the type 1 cell function as autoreceptors to control DA release and/or synthesis. The aim of the study was to compa...

journal_title：Archives of physiology and biochemistry

authors： Basson H,Bairam A,Cottet-Emard JM,Pequignot JM,Marchal F

更新日期：1997-02-01 00:00:00