Incretin hormones and beta-cell mass expansion: what we know and what is missing?

abstract：:A novel molecular mechanism for the regulation of lipid metabolism by palmitate, H2O2 and the anti-diabetic sulfonylurea drug, glimepiride, in rat adipocytes was recently elucidated. It encompasses the translocation of the glycosylphosphatidylinositol-anchored (GPI-) and (c)AMP degrading enzymes Gce1 and CD73 from det...

journal_title：Archives of physiology and biochemistry

authors： Müller G,Schulz A,Dearey EA,Wetekam EM,Wied S,Frick W

更新日期：2010-07-01 00:00:00

abstract：:Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

journal_title：Archives of physiology and biochemistry

authors： Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

更新日期：2019-09-13 00:00:00

abstract：:The purpose of this study was to measure the running velocity corresponding to the individual maximal lactate steady-state of a group of 12-year old boys and girls on a treadmill. This running velocity (v MLST) was compared with the maximal aerobic running velocity (v a max) at which maximal oxygen uptake (VO2 max) oc...

journal_title：Archives of physiology and biochemistry

authors： Billat V,Gratas-Delamarche A,Monnier M,Delamarche P

更新日期：1995-04-01 00:00:00

abstract：:Background: Oxidative stress, has been shown to play an important role in the pathophysiology of cardiac remodelling and heart failure. The aim of study is effect of arginine vasopressin (AVP) on apoptosis of cardiomyocyte via its receptors.Materials and methods: The cell viability effect of AVP in H9C2 cardiomyocytes...

journal_title：Archives of physiology and biochemistry

authors： Ghorbanzadeh V,Jafarpour A,Pirnia A,Pajouhi N,Khaksarian M,Veiskarami S,Nazari A

更新日期：2020-03-06 00:00:00

abstract：:Introduction: There are few studies examining the effect of spinosad on cognitive functions in the literature. Methods: In this study, we applied spinosad 3 weeks in different doses to mice and examined their effects on antioxidant system and cognitive performance. Results: In the open field test, we observed a signif...

journal_title：Archives of physiology and biochemistry

authors： Acar A,Akkoc H,Erdinc M

更新日期：2019-06-07 00:00:00

abstract：:Ethanol-consumption impairs physiological-efficiency/endurance, expedites senescence. Impaired-regulations of steroids/biomolecules link these processes. Steroids are catabolized by cytosolic-sulfotransferases (SULTs). Ethanol-induction of eukaryotic-SULTs-expression is scanty. Plant (Brassica-napus) steroid-sulfotran...

journal_title：Archives of physiology and biochemistry

authors： Maiti S,Chen G

更新日期：2015-05-01 00:00:00

abstract：AIM:To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians. METHODS:It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels...

journal_title：Archives of physiology and biochemistry

authors： Nayak S,Soon SQ,Kunjal R,Ramadoo R,Baptiste O,Persad J,Temull V,Diptee L,Balgobin S

更新日期：2009-02-01 00:00:00

abstract：:Objective: To evaluate the effect of the administration of phytoestrogens on obesity, type 2 diabetes, and liver-kidney toxicity. Methods: Phytoestrogens (phyto(E2)) were administrated to high fructose-fat diet (HFFD). Results: This study showed that administration of phyto(E2) to HFFD-mice inhibited lipase activity b...

journal_title：Archives of physiology and biochemistry

authors： Hamden K,Boujibiha MA,Ben Abdeljelil N,Njima M,Selmi B,Achour L

更新日期：2019-12-01 00:00:00

abstract：:To investigate the antidiabetic effect of isopulegol in high-fat diet (HFD)/streptozotocin (STZ)-induced diabetic rats. Animals were made diabetic by feeding HFD for 4 weeks followed by single intraperitoneal injection of STZ (35 mg/kg b.w.; 0.1 M citrate buffer; pH 4.0). Plasma insulin, haemoglobin and glycogen conte...

journal_title：Archives of physiology and biochemistry

authors： Kalaivani K,Sankaranarayanan C

更新日期：2019-07-10 00:00:00

abstract：:The mechanism underlying the increased rate of endogenous glucose production from the liver during exercise remains unknown. The cytokine interleukin-6 (IL-6) is known to be released during exercise and is thought that either IL-6 directly or via a "contraction factor" stimulates the release of stored glucose from the...

journal_title：Archives of physiology and biochemistry

authors： Dent JR,Chowdhury MK,Tchijov S,Dulson D,Smith G

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The potentially beneficial effects of pomegranate peel (PPE), flower (PFE) and seed oil (PSO) extracts, in comparison with rosiglitazone, on adiposity, lipid profile, glucose homoeostasis, as well as on the underlying inflammatory mechanisms, were examined in high-fat and high-sucrose (HF/HS) diet-induced obe...

journal_title：Archives of physiology and biochemistry

authors： Harzallah A,Hammami M,Kępczyńska MA,Hislop DC,Arch JR,Cawthorne MA,Zaibi MS

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. OBJECTIVE:To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. MATERIALS AND METHODS:Rats were divided into control, sham, sham + ghreli...

journal_title：Archives of physiology and biochemistry

authors： Eid RA,Alkhateeb MA,Al-Shraim M,Eleawa SM,Shatoor AS,El-Kott AF,Zaki MSA,Shatoor KA,Bin-Jaliah I,Al-Hashem FH

更新日期：2019-05-01 00:00:00

abstract：:Mammalian gonadotropin-releasing hormone (GnRH I) is a hypothalamic decapeptide that governs gonadotropin secretion through interaction with its seven transmembrane (7TM), G protein-coupled receptor (GPCR) expressed by anterior pituitary cells. A second decapeptide, GnRH II, originally discovered in the chicken hypoth...

journal_title：Archives of physiology and biochemistry

authors： Neill JD

更新日期：2002-04-01 00:00:00

abstract：:When neurotransmitters bind to their specific receptors in the membrane of nerve and muscle cells they induce conformational transitions leading to the formation of open receptor-channels and desensitized receptor forms. A knowledge of the rate and equilibrium constants associated with these transitions is required to...

journal_title：Archives of physiology and biochemistry

authors： Hess GP

更新日期：1996-10-01 00:00:00

abstract：:Background: The microRNAs have come up as crucial mediators of energy balance and metabolic control. CD36 is potential biomarker of obesity and metabolic syndrome. This study investigates the concentration of miR-146a and miR-21 and CD 36 in blood samples of obese and healthy young participants. We assessed the associ...

journal_title：Archives of physiology and biochemistry

authors： Benbaibeche H,Hichami A,Oudjit B,Haffaf EM,Kacimi G,Koceïr EA,Khan NA

更新日期：2020-06-13 00:00:00

abstract：:The effect of underfeeding over glucose metabolism in uteri isolated from ovariectomized and non-ovariectomized rats subjected to a restricted diet for 25 days (50% of the normal food intake), was studied. Underfeeding decreases (14)CO(2) formation from U(14) C-glucose in intact animal uteri. While in ovariectomized r...

journal_title：Archives of physiology and biochemistry

authors： Campos ML,Casalino-Matsuda SM,Linares JA,Goldraij A

更新日期：2000-12-01 00:00:00

abstract：:To explain the role of the different portions of the stomach in the genesis of electrical signal obtained from abdominal surface (Electrogastrography, EGG), the EGG was recorded in 6 patients with gastric cancer and 7 with duodenal ulcer before and after total gastrectomy or Billroth II gastric resection, respectively...

journal_title：Archives of physiology and biochemistry

authors： Riezzo G,Pezzolla F,Giorgio I

更新日期：1996-01-01 00:00:00

abstract：CONTEXT:Glucose-6-phosphate dehydrogenase (G6PD) is an important enzyme of hexose monophosphate shunt, involved in the biosynthesis of reduced nicotinamide adenine dinucleotide phosphate hydrogen (NADPH). OBJECTIVE:This study was designed to investigate age-dependent changes in human erythrocyte G6PD activity. The G6P...

journal_title：Archives of physiology and biochemistry

authors： Maurya PK,Kumar P,Chandra P

更新日期：2016-01-01 00:00:00

abstract：:Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. In recent years, considerable interest has been focused on curcumin due to its use to treat a wide variety of disorders without any side effects. It is one of the major curcuminoids of turmeric,...

journal_title：Archives of physiology and biochemistry

authors： Pari L,Tewas D,Eckel J

更新日期：2008-04-01 00:00:00

abstract：CONTEXT:Diabetic retinopathy (DR) is the leading cause of acquired blindness. The involvement of indoleamine 2, 3-dioxygenase (IDO) and kynurenines, the products of tryptophan degradation in various pathological conditions was well documented. OBJECTIVE:The aim of the present study was to determine the expression of I...

journal_title：Archives of physiology and biochemistry

authors： Munipally PK,Agraharm SG,Valavala VK,Gundae S,Turlapati NR

更新日期：2011-12-01 00:00:00

abstract：:Objective: The present study aimed to investigate the effects of Juglans regia (JR) extract on hyperglycaemia and insulin sensitivity. Methods: Forty rats were divided into 4 groups: Control (C), Diabetes Control (DC), Diabetes + Juglans regia (D + JR) and Diabetes + Metformin (D + M). Results: In the D + JR group, Fa...

journal_title：Archives of physiology and biochemistry

authors： Atila Uslu G,Uslu H

更新日期：2019-09-23 00:00:00

abstract：CONTEXT:Metabolic syndrome (MetS) is a clustering of several physiological alterations. OBJECTIVE:This study was designed to evaluate the effects of MetS on rats spermatogenesis and steroidogenesis. MATERIALS AND METHODS:We developed a MetS rodent model using high-sugar and high-fat diet. RESULTS:MetS rats showed se...

journal_title：Archives of physiology and biochemistry

authors： Rahali D,Dallagi Y,Hupkens E,Veegh G,Mc Entee K,Asmi ME,El Fazaa S,El Golli N

更新日期：2020-09-04 00:00:00

abstract：:This study was carried out to determine a possible relationship between hepatic acetyl-coenzyme A carboxylase EC 6.4.1.2 (ACC) activity in dam and fetus at 15-day and 19-day of gestation and the glucose tolerance in pregnant rats fed on the sucrose diet compared with the rats feed on the dextrin diet. Sucrose feeding ...

journal_title：Archives of physiology and biochemistry

authors： Oliveros L,Callegari E,Giménez MS

更新日期：1997-12-01 00:00:00

abstract：:Type 2 Diabetes mellitus (T2D) is the most common endocrine disorder associated to metabolic syndrome (MS) and occurs when insulin secretion can no compensate peripheral insulin resistance. Among peripheral tissues, the liver controls glucose homeostasis due to its ability to consume and produce glucose. The molecular...

journal_title：Archives of physiology and biochemistry

authors： Valverde AM,González-Rodríguez A

更新日期：2011-07-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is the most prevalent disease and becoming a serious public health threat worldwide. In recent years, numerous effective T2DM intervention regimens have been developed, with promising results. However, these regimens are not usually economically available, and they are not well tolerate...

journal_title：Archives of physiology and biochemistry

authors： El-Tantawy WH

更新日期：2019-09-02 00:00:00

abstract：:We reasoned that micro-dissection of tumour cells for protein expression studies should be omitted since tumour-stroma interactions are an important part of the biology of solid tumours. To study such interactions in head and neck squamous cell carcinoma (HNSCC) development, we generated reference protein spectra for ...

journal_title：Archives of physiology and biochemistry

authors： Roesch-Ely M,Schnölzer M,Nees M,Plinkert PK,Bosch FX

更新日期：2010-10-01 00:00:00

abstract：:The spatial disparity sensitivity of single units in the primary visual cortex (17-18 border), in extrastriate area 19 and in the superficial layers of the superior colliculus of the cat brain were compared in the present study. Unit recordings were performed in paralyzed and anesthetized animals. Centrally located re...

journal_title：Archives of physiology and biochemistry

authors： Bacon BA,Lepore F,Guillemot JP

更新日期：1998-07-01 00:00:00

abstract：:The G0/G1 switch gene 2 (G0S2) protein attenuated adipose triglyceride lipase (ATGL) activity and decreased lipolysis in rodent and human adipocytes. We hypothesized that G0S2 mRNA expression in human adipose tissue is influenced by depot, adipocyte size, body weight and caloric intake. Adipose tissue samples were obt...

journal_title：Archives of physiology and biochemistry

authors： Skopp A,May M,Janke J,Kielstein H,Wunder R,Flade-Kuthe R,Kuthe A,Jordan J,Engeli S

更新日期：2016-01-01 00:00:00

abstract：:Objective: To explore the probable in vitro, in situ and in vivo mechanisms of gallic acid (GA) and p-coumaric acid (PCA) as anti-hyperglycemic agents.Animals and methods: Male albino rats were allocated into four groups, group1 was used as normal control. Group 2 was established as a diabetic control and group3 and 4...

journal_title：Archives of physiology and biochemistry

authors： Abdel-Moneim A,Abd El-Twab SM,Yousef AI,Ashour MB,Reheim ESA,Hamed MAA

更新日期：2020-05-13 00:00:00

abstract：OBJECTIVES:To determine the awareness of HbA1c values and correlate this with educational levels, dietary intake and physical activity in type II diabetic population of Trinidad. METHODS:Total of 222 type II diabetic subjects were assessed via questionnaire evaluating their demographics, type and duration of diabetes,...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Khan K,Kidney C,Knowles V,Koo A,Lakhan A,Lalla D,Lalloo C,Lallo SA,Singh S

更新日期：2018-12-01 00:00:00