Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients.

abstract：:Phospholipid fatty acid composition and bilirubin UDP-glucuronyltransferase activity from liver microsomal membrane were studied in normal and in bile duct ligated rats. Incubation of normal microsomes with 15 microM bilirubin (considered as physiological concentration) yielded 60% bilirubin diglucuronide; in 2 days p...

journal_title：Archives of physiology and biochemistry

authors： Ouviña CB,Pavese CB,Lemberg A,Bengochea LA

更新日期：1995-08-01 00:00:00

abstract：:The influence of ageing on the capacity to increase muscle oxygen delivery during exercise is unclear. This was investigated by comparing the evolution of Near InfraRed Spectroscopy (NIRS) in 10 old (67 +/- 5 years, Old group) and 13 young subjects (27 +/- 4 years, Young group), during a progressive maximal exercise. ...

journal_title：Archives of physiology and biochemistry

authors： Costes F,Denis C,Roche F,Prieur F,Enjolras F,Barthélémy JC

更新日期：1999-04-01 00:00:00

abstract：:Arecoline is known to cause endocrine dysfunction. In the current article role of arecoline on pineal-testis activity was investigated in hypothyroid rats induced by propylthiouracil (PTU). PTU treatment caused thyroid dysfunction ultrastructurally with a fall in T3 and T4 levels followed by a rise of thyroid stimulat...

journal_title：Archives of physiology and biochemistry

authors： Saha I,Chakraborty SB,Chatterjee A,Pradhan D,Chatterji U,Maiti BR

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:NAFLD patients have higher risk of atherosclerosis cardiovascular disease (ASCVD). apo B/apoA-I ratio and atherogenic index of plasma (AIP) have been suggested as biomarker for ASCVD. METHODS:apo A-I, apoB, aryl esterase (ARE) and paraoxonase (PON) activities and carotid intima media thickness (cIMT) were d...

journal_title：Archives of physiology and biochemistry

authors： Fadaei R,Meshkani R,Poustchi H,Fallah S,Moradi N,Panahi G,Merat S,Golmohammadi T

更新日期：2019-02-01 00:00:00

abstract：:Due to the importance of zinc as an antioxidant and its crucial role in insulin synthesis, its deficiency may affect adversely diabetic state. So, this study aimed to modulate these effects using Curcuma longa as natural antioxidant. Rats were divided into four groups: two groups fed a zinc sufficient diet one non-dia...

journal_title：Archives of physiology and biochemistry

authors： Tebboub I,Kechrid Z

更新日期：2019-06-19 00:00:00

abstract：:Diabetic cardiomyopathy consists of a series of structural and functional changes. Accumulating evidence supports the concept that a "cardiac stem cell compartment disease" plays an important role in the pathophysiology of diabetic cardiomyopathy. In diabetic hearts, human cardiac stem/progenitor cells (CSPC) are redu...

journal_title：Archives of physiology and biochemistry

authors： Leonardini A,Avogaro A

更新日期：2013-10-01 00:00:00

abstract：:Cytotoxic effects, including oxidative stress, of low linear energy transfer (LET)-ionizing radiation are often underestimated and studies of their mechanisms using cell culture models are widely conducted with cells cultivated at atmospheric oxygen that does not match its physiological levels in body tissues. Also, c...

journal_title：Archives of physiology and biochemistry

authors： Džinić T,Hartwig S,Lehr S,Dencher NA

更新日期：2016-12-01 00:00:00

abstract：:Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

journal_title：Archives of physiology and biochemistry

authors： Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

更新日期：2019-09-13 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:Objective: The pattern of urinary excretion of total sulphated glycosaminoglycans (GAGs) and their particular types: chondroitin sulphate/dermatan sulphate (CS/DS) and heparan sulphate (HS) was analysed in obese patients with type 2 diabetes mellitus (T2DM) treated with metformin in monotherapy for the period of six m...

journal_title：Archives of physiology and biochemistry

authors： Jura-Półtorak A,Olczyk P,Chałas-Lipka A,Komosińska-Vassev K,Kuźnik-Trocha K,Winsz-Szczotka K,Ivanova D,Kiselova-Kaneva Y,Krysik K,Telega A,Olczyk K

更新日期：2019-12-09 00:00:00

abstract：:Diabetes represents an important public health problem. Recently, new molecular targets have been identified and exploited to treat this disease. Due to its pivotal role in glucose homeostasis, glucokinase (GCK) is a promising target for the development of novel antidiabetic drugs; however, pharmacological agents that...

journal_title：Archives of physiology and biochemistry

authors： Guzmán TJ,Gurrola-Díaz CM

更新日期：2019-06-18 00:00:00

abstract：:Diabetes is associated with depression and anxiety symptoms. The current investigation was designed to explore the effect of melatonin on depressive and anxiety like-behaviours, oxidative stress, levels of AGE, RAGE and S100B in streptozotocin-induced diabetic rats. The animals were divided into four groups: Normoglyc...

journal_title：Archives of physiology and biochemistry

authors： Ergenc M,Ozacmak HS,Turan I,Ozacmak VH

更新日期：2019-11-15 00:00:00

abstract：:It is known that oxidative stress plays an important role in the chronic complications of diabetes. Lipid peroxidation is one of the consequences of oxidative stress. Erythrocyte deformability abilities are reduced as a result of lipid peroxidation. Conversely, a decrease nitric oxide (NO) production seems to be respo...

journal_title：Archives of physiology and biochemistry

authors： Yapislar H,Aydogan S

更新日期：2012-12-01 00:00:00

abstract：:This research was designed to detect the function of low-density lipoprotein receptor (LDLR)-related protein 8 (LRP8) in breast cancer (BC). Our results revealed that LRP8 was highly expressed in BC tissues and cell lines compared with human normal breast tissues. The poor prognosis of patients with BC was associated ...

journal_title：Archives of physiology and biochemistry

authors： Li L,Qu WH,Ma HP,Wang LL,Zhang YB,Ma Y

更新日期：2020-01-29 00:00:00

abstract：:Curcumin (diferuloylmethane) is an orange-yellow component of turmeric (Curcuma longa), a spice often found in curry powder. In recent years, considerable interest has been focused on curcumin due to its use to treat a wide variety of disorders without any side effects. It is one of the major curcuminoids of turmeric,...

journal_title：Archives of physiology and biochemistry

authors： Pari L,Tewas D,Eckel J

更新日期：2008-04-01 00:00:00

abstract：:For the identification of proteins from biological samples by mass spectrometry there are two scenarios. Proteins are pre-fractionated in some way or are analysed as a complex mixture (shotgun). Shotgun proteomics recently became more popular, because of technological developments on the mass spectrometer side which n...

journal_title：Archives of physiology and biochemistry

authors： Li X,Franz T

更新日期：2014-12-01 00:00:00

abstract：:The dysregulation of microRNA expression is significantly associated with the initiation and development of CRC. miR-124 is markedly downregulated in colorectal cancer. In the present study, the effects of methylation, over expression and downregulation of miR-124 and its target gene DNMT3B on the proliferation, migra...

journal_title：Archives of physiology and biochemistry

authors： Shahmohamadnejad S,Nouri Ghonbalani Z,Tahbazlahafi B,Panahi G,Meshkani R,Emami Razavi A,Shokri Afra H,Khalili E

更新日期：2020-06-18 00:00:00

abstract：:Pyruvate carboxylase (PC) has been quantified in rat liver and kidney cortex under experimental conditions that modify the gluconeogenic response in both organs: fasting, carbon tetrachloride-induced liver degeneration and alloxan-induced diabetes. Enzymatic activity has been assayed by a 14CO2-fixation method. The am...

journal_title：Archives of physiology and biochemistry

authors： Salto R,Sola M,Oliver FJ,Vargas AM

更新日期：1996-12-01 00:00:00

abstract：:The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or reproduction are well known; however, the interactions between these hormones remain unclear, especially in humans. The aim of this study was to determine the roles of leptin, nesfatin-1 and kisspeptin in pre- and postmenopausal obe...

journal_title：Archives of physiology and biochemistry

authors： Çelik F,Belviranli M,Okudan N

更新日期：2016-10-01 00:00:00

abstract：:Pulmonary ischemia-reperfusion (IR) injury may result from trauma, atherosclerosis, pulmonary embolism, pulmonary thrombosis and surgical procedures such as cardiopulmonary bypass and lung transplantation. IR injury induces oxidative stress characterized by formation of reactive oxygen (ROS) and reactive nitrogen spec...

journal_title：Archives of physiology and biochemistry

authors： Ovechkin AV,Lominadze D,Sedoris KC,Robinson TW,Tyagi SC,Roberts AM

更新日期：2007-02-01 00:00:00

abstract：:A novel molecular mechanism for the regulation of lipid metabolism by palmitate, H2O2 and the anti-diabetic sulfonylurea drug, glimepiride, in rat adipocytes was recently elucidated. It encompasses the translocation of the glycosylphosphatidylinositol-anchored (GPI-) and (c)AMP degrading enzymes Gce1 and CD73 from det...

journal_title：Archives of physiology and biochemistry

authors： Müller G,Schulz A,Dearey EA,Wetekam EM,Wied S,Frick W

更新日期：2010-07-01 00:00:00

abstract：:In the last decade proteomics has made great progress reaching throughput and comprehensiveness comparable to genomics technologies. Mass spectrometry plays a key role in proteomics and has become an indispensable method for molecular and cellular biology because many cellular changes in response to internal or extern...

journal_title：Archives of physiology and biochemistry

authors： Fröbel J,Lehr S,Haas R,Czibere A

更新日期：2009-12-01 00:00:00

abstract：:A range of epidemiological evidence from several diverse populations, supports the hypothesis that risk of essential hypertension, coronary heart disease and non-insulin dependent diabetes is, in part, programmed by intrauterine nutritional status. Animal models developed to investigate the mechanisms that are respons...

journal_title：Archives of physiology and biochemistry

authors： Langley-Evans SC,Langley-Evans AJ,Marchand MC

更新日期：2003-02-01 00:00:00

abstract：:The current in-vivo study was premeditated to uncover the protective role of ezetimibe (EZ) against advanced glycation endproducts (AGEs)-related pathologies in experimental diabetes. Our results showed that EZ markedly improved the altered biochemical markers of diabetes mellitus (DM) (FBG, HbA1c, insulin, microalbum...

journal_title：Archives of physiology and biochemistry

authors： Nabi R,Alvi SS,Shah A,Chaturvedi CP,Faisal M,Alatar AA,Ahmad S,Khan MS

更新日期：2021-01-29 00:00:00

abstract：:Hepatotoxicity, induced by aluminium chloride (AlCl3), has been well studied but there are no reports about liver metallothionein (MT) genes induction. Therefore, it is of interest to establish the mechanism involving the relation between MT gene expression levels and the oxidative stress status in hepatic cells of al...

journal_title：Archives of physiology and biochemistry

authors： Ghorbel I,Chaabane M,Elwej A,Boudawara O,Abdelhedi S,Jamoussi K,Boudawara T,Zeghal N

更新日期：2016-10-01 00:00:00

abstract：:Background: We aim to identify and analyze the expression of dyregulated RNAs in colorectal cancer (CRC). Methods: We selected a panel of RNAs specific to CRC composed of Nucleosome Assembly Protein 1 Like 2 (NAP1L2) mRNA, LNCRNA SNHG14 small nucleolar RNA host gene 14 (LNCRNA SNHG14) and homo sapiens microRNA-3940-5p...

journal_title：Archives of physiology and biochemistry

authors： Matboli M,Shafei AE,Ali MA,El-Din Ahmed TS,Naser M,Abdel-Rahman T,Anber N,Ali M

更新日期：2019-08-09 00:00:00

abstract：:Objective, materials and methods: The aim of this cross-sectional study with a consecutive enrolment was to analyse the role of high sensitive C-reactive protein (hs-CRP) measurement in similarly obese patients with and without the metabolic syndrome (MS). Results: In total, 589 obese patients were screened, of whom 1...

journal_title：Archives of physiology and biochemistry

authors： Kucharska A,Sawicka-Gutaj N,Owecki M

更新日期：2019-02-01 00:00:00

abstract：:The effect of underfeeding over glucose metabolism in uteri isolated from ovariectomized and non-ovariectomized rats subjected to a restricted diet for 25 days (50% of the normal food intake), was studied. Underfeeding decreases (14)CO(2) formation from U(14) C-glucose in intact animal uteri. While in ovariectomized r...

journal_title：Archives of physiology and biochemistry

authors： Campos ML,Casalino-Matsuda SM,Linares JA,Goldraij A

更新日期：2000-12-01 00:00:00

abstract：:Separating proteins according to two different gel-electrophoretic methods not only increases the resolution power for highly complex samples when compared to one-dimensional separations, but is also a valuable tool for protein and protein complex characterization. There are a number of different electrophoresis metho...

journal_title：Archives of physiology and biochemistry

authors： Westermeier R

更新日期：2014-12-01 00:00:00

abstract：:Type 2 Diabetes mellitus (T2D) is the most common endocrine disorder associated to metabolic syndrome (MS) and occurs when insulin secretion can no compensate peripheral insulin resistance. Among peripheral tissues, the liver controls glucose homeostasis due to its ability to consume and produce glucose. The molecular...

journal_title：Archives of physiology and biochemistry

authors： Valverde AM,González-Rodríguez A

更新日期：2011-07-01 00:00:00