Glucokinase activation as antidiabetic therapy: effect of nutraceuticals and phytochemicals on glucokinase gene expression and enzymatic activity.

abstract：:A-4166, a phenylalanine derivative, is a hypoglycemic agent, which has been shown to improve blood glucose levels mainly due to the rapid and short term stimulation of insulin release. Nevertheless, a possible extrapancreatic action of A-4166 has not yet been investigated. Therefore, insulin action (euglycemic hyperin...

journal_title：Archives of physiology and biochemistry

authors： Klimes I,Mitková A,Gasperíková D,Ukropec J,Líska B,Bohov P,Stanek J,Seböková E

更新日期：1998-10-01 00:00:00

abstract：:Pulmonary ischemia-reperfusion (IR) injury may result from trauma, atherosclerosis, pulmonary embolism, pulmonary thrombosis and surgical procedures such as cardiopulmonary bypass and lung transplantation. IR injury induces oxidative stress characterized by formation of reactive oxygen (ROS) and reactive nitrogen spec...

journal_title：Archives of physiology and biochemistry

authors： Ovechkin AV,Lominadze D,Sedoris KC,Robinson TW,Tyagi SC,Roberts AM

更新日期：2007-02-01 00:00:00

abstract：:This research was designed to detect the function of low-density lipoprotein receptor (LDLR)-related protein 8 (LRP8) in breast cancer (BC). Our results revealed that LRP8 was highly expressed in BC tissues and cell lines compared with human normal breast tissues. The poor prognosis of patients with BC was associated ...

journal_title：Archives of physiology and biochemistry

authors： Li L,Qu WH,Ma HP,Wang LL,Zhang YB,Ma Y

更新日期：2020-01-29 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is the most prevalent disease and becoming a serious public health threat worldwide. In recent years, numerous effective T2DM intervention regimens have been developed, with promising results. However, these regimens are not usually economically available, and they are not well tolerate...

journal_title：Archives of physiology and biochemistry

authors： El-Tantawy WH

更新日期：2019-09-02 00:00:00

abstract：:Studies about bone formation and regulation are complex due to a close relationship between bone cells. Primary cell cultures allow to understand osteoblastic function. We isolated cells from the cortical metacarpal bone of 85 or 120 day-old ovine fetuses by an enzymatic method. After first passage and cell amplificat...

journal_title：Archives of physiology and biochemistry

authors： Collignon H,Davicco MJ,Barlet JP

更新日期：1997-04-01 00:00:00

abstract：:Aberrant expression of miRNAs has a link with tumorgenesis and their deregulation is reported in biological fluids of cancer patients. Authors aimed to investigate the diagnostic role of miRNA-17-5p, miR-155 and miRNA-222 in serum samples from breast cancer patients (n = 80), benign breast patients (n = 40) and health...

journal_title：Archives of physiology and biochemistry

authors： Swellam M,Zahran RFK,Abo El-Sadat Taha H,El-Khazragy N,Abdel-Malak C

更新日期：2019-12-01 00:00:00

abstract：:Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in...

journal_title：Archives of physiology and biochemistry

authors： Hosseini SA,Hamzavi K,Safarzadeh H,Salehi O

更新日期：2020-10-05 00:00:00

abstract：:Arecoline is known to cause endocrine dysfunction. In the current article role of arecoline on pineal-testis activity was investigated in hypothyroid rats induced by propylthiouracil (PTU). PTU treatment caused thyroid dysfunction ultrastructurally with a fall in T3 and T4 levels followed by a rise of thyroid stimulat...

journal_title：Archives of physiology and biochemistry

authors： Saha I,Chakraborty SB,Chatterjee A,Pradhan D,Chatterji U,Maiti BR

更新日期：2020-02-01 00:00:00

abstract：:When neurotransmitters bind to their specific receptors in the membrane of nerve and muscle cells they induce conformational transitions leading to the formation of open receptor-channels and desensitized receptor forms. A knowledge of the rate and equilibrium constants associated with these transitions is required to...

journal_title：Archives of physiology and biochemistry

authors： Hess GP

更新日期：1996-10-01 00:00:00

abstract：CONTEXT:The important role of exercise in pulmonary function during menopause is not well known. Oestrogen deficiency in ageing female mice is accompanied by increase in apoptotic markers such as caspase3 in the lung. OBJECTIVE:The present study was designed to investigate whether swimming training will ameliorate fib...

journal_title：Archives of physiology and biochemistry

authors： Daghigh F,Alihemmati A,Karimi P,Habibi P,Ahmadiasl N

更新日期：2018-10-01 00:00:00

abstract：CONTEXT:Diabetic retinopathy (DR) is the leading cause of acquired blindness. The involvement of indoleamine 2, 3-dioxygenase (IDO) and kynurenines, the products of tryptophan degradation in various pathological conditions was well documented. OBJECTIVE:The aim of the present study was to determine the expression of I...

journal_title：Archives of physiology and biochemistry

authors： Munipally PK,Agraharm SG,Valavala VK,Gundae S,Turlapati NR

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:Examine the diagnostic role of serum exosomal RAB27A mRNA in lung cancer and evaluate the relation of LncRNAs to lung cancer in association to RAB27A mRNA in Egyptian population. METHODS:Exosomal RNA-based biomarkers RAB27A mRNA and Lnc-RNA-RP11-510M2.10 were selected based on bioinformatic methods, followe...

journal_title：Archives of physiology and biochemistry

authors： Mohamed Gamal El-Din G,Ibrahim FK,Shehata HH,Osman NM,Abdel-Rahman OM,Ali M

更新日期：2020-07-13 00:00:00

abstract：:To explain the role of the different portions of the stomach in the genesis of electrical signal obtained from abdominal surface (Electrogastrography, EGG), the EGG was recorded in 6 patients with gastric cancer and 7 with duodenal ulcer before and after total gastrectomy or Billroth II gastric resection, respectively...

journal_title：Archives of physiology and biochemistry

authors： Riezzo G,Pezzolla F,Giorgio I

更新日期：1996-01-01 00:00:00

abstract：:Objective: To evaluate the effect of the administration of phytoestrogens on obesity, type 2 diabetes, and liver-kidney toxicity. Methods: Phytoestrogens (phyto(E2)) were administrated to high fructose-fat diet (HFFD). Results: This study showed that administration of phyto(E2) to HFFD-mice inhibited lipase activity b...

journal_title：Archives of physiology and biochemistry

authors： Hamden K,Boujibiha MA,Ben Abdeljelil N,Njima M,Selmi B,Achour L

更新日期：2019-12-01 00:00:00

abstract：:This study investigates the effects of the islet hormones insulin (Ins), glucagon (Glu), and somatostatin (Som) with nerve stimulation (EFS) acetylcholine (ACh) and cholecytokinin-octapeptide (CCK-8) on amylase secretion and intracellular free calcium concentration [Ca(2+)](i) in the pancreas of age-matched control an...

journal_title：Archives of physiology and biochemistry

authors： Singh J,Yago MD,Adeghate E

更新日期：2001-07-01 00:00:00

abstract：:This study investigates the alcoholic extract effect of Alhagi camelorum on blood glucose and lipid profiles in diabetic rats made by streptozotocin (STZ). Male rats were divided into four groups. The control group received a normal diet. The diabetic group was induced by STZ and two diabetic experimental groups recei...

journal_title：Archives of physiology and biochemistry

authors： Nabiyouni F,Vaezi G,Malekirad AA

更新日期：2019-08-04 00:00:00

abstract：:Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...

journal_title：Archives of physiology and biochemistry

authors： Tortosa F,Dotta F

更新日期：2013-10-01 00:00:00

abstract：:Folliculo-stellate cells (FS-cells) in the anterior pituitary gland are star-shaped cells and form tiny follicles. FS-cells are positive for S-100 protein and produce many cytokines or growth factors, such as interleukin-6 (IL-6), leukemia inhibitory factor (LIF), basic fibroblastic growth factor (bFGF) and vascular e...

journal_title：Archives of physiology and biochemistry

authors： Inoue K,Mogi C,Ogawa S,Tomida M,Miyai S

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:A substantial body of evidence links sex hormones, diet, excess body weight and physical activity to the risk of developing cancer at several sites common in affluent countries. The hypothesis that high circulating levels of insulin could be the underlying factor increasing cancer risk has been proposed. Epi...

journal_title：Archives of physiology and biochemistry

authors： Pisani P

更新日期：2008-02-01 00:00:00

abstract：:Context: Follistatin-like 1 (FSTL1) and apelin exert a favourable effect on energy metabolism.Objective: We examined the effects of acute endurance exercise on the levels of FSTL1 and apelin in the serum and metabolic organs of rats.Methods: Rats were divided into two groups: a sedentary control (CON, n = 8) group and...

journal_title：Archives of physiology and biochemistry

authors： Kon M,Tanimura Y,Yoshizato H

更新日期：2020-05-15 00:00:00

abstract：:Spirulina platensis, is an alga rich in phycocyanin (potent antioxidant), is effective in regulating the balance of oxidative stress. The objective of this study is to observe the impact of ingestion of a highly oxidised vegetable oil, by rats of Wistar strain. Finally, we observe the effect of Spirulina used as an an...

journal_title：Archives of physiology and biochemistry

authors： Ould Amara-Leffad L,Ramdane H,Nekhoul K,Ouznadji A,Koceir EA

更新日期：2019-05-01 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:Type 2 Diabetes mellitus (T2D) is the most common endocrine disorder associated to metabolic syndrome (MS) and occurs when insulin secretion can no compensate peripheral insulin resistance. Among peripheral tissues, the liver controls glucose homeostasis due to its ability to consume and produce glucose. The molecular...

journal_title：Archives of physiology and biochemistry

authors： Valverde AM,González-Rodríguez A

更新日期：2011-07-01 00:00:00

abstract：:We investigated the effects of tauroursodeoxycholic acid (TUDCA) to assess whether this acid may also have "protective" effects similar to those found with ursodeoxycholic acid (UDCA). We used a well-known amphibian model of gastric mucosa, and studied the effects of taurodeoxycholic acid (TDCA) on electrical transepi...

journal_title：Archives of physiology and biochemistry

authors： Piepoli AL,Caroppo R,Armentano R,Caruso ML,Guerra V,Maselli MA

更新日期：2002-07-01 00:00:00

abstract：CONTEXT:Cardiometabolic disorders are rapidly becoming major public health challenges. Valproic acid (VPA) is a widely prescribed anticonvulsant drug. OBJECTIVE:We hypothesized that treatment with VPA would improve the regulation of glucose and atherogenic dyslipidemia through reduction in circulating corticosterone. ...

journal_title：Archives of physiology and biochemistry

authors： Olatunji LA,Omolekulo TE,Usman TO,Kim I

更新日期：2016-07-01 00:00:00

abstract：AIM:To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians. METHODS:It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels...

journal_title：Archives of physiology and biochemistry

authors： Nayak S,Soon SQ,Kunjal R,Ramadoo R,Baptiste O,Persad J,Temull V,Diptee L,Balgobin S

更新日期：2009-02-01 00:00:00

abstract：:The objective of the study was to investigate the association of blood glucose and lipid profile parameters with cognitive impairment in schizophrenia. A total of 200 schizophrenia patients and 169 controls were enrolled in the study. Blood glucose and lipid profile were estimated in all the subjects. Cognition was as...

journal_title：Archives of physiology and biochemistry

authors： Nandeesha H,Keshri N,Rajappa M,Menon V

更新日期：2020-11-03 00:00:00

abstract：:This study investigated the effects of garlic on anxiety- and depression-related behaviors and brain oxidative markers in streptozotocin (STZ)-induced diabetes in rats. Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8/group): control, diabetic + saline, diabetic + garlic, diabetic...

journal_title：Archives of physiology and biochemistry

authors： Rahmani G,Farajdokht F,Mohaddes G,Babri S,Ebrahimi V,Ebrahimi H

更新日期：2020-05-01 00:00:00

abstract：:Changes in body fluid distribution are known to influence neuroendocrine function. The aim of the present study was to test the hypothesis that changes in plasma volume affect the counterregulatory neuroendocrine response to hypoglycemia. The tests were performed in 12 subjects in two situations: 'head-up' (+60 degree...

journal_title：Archives of physiology and biochemistry

authors： Radikova Z,Penesova A,Jezova D,Kvetnansky R,Vigas M,Macho L,Koska J

更新日期：2003-10-01 00:00:00

abstract：:Recent studies reported good intra-individual reproducibility, but great inter-individual variation in a sample of elite athletes, in time to exhaustion (tlim) at the maximal aerobic speed (MAS: the lowest speed that elicits VO2max in an incremental treadmill test). The purpose of the present study was, on the one han...

journal_title：Archives of physiology and biochemistry

authors： Gazeau F,Koralsztein JP,Billat V

更新日期：1997-10-01 00:00:00