Relationship between adiponectin, inflammatory markers and obesity in type 2 diabetic and non-diabetic Trinidadians.

Abstract:

AIM:To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians. METHODS:It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels, lipid profiles and glucose were measured in fasting blood samples. RESULTS:Adiponectin levels were significantly lower (P = 0.003) in diabetics (n = 60) than non diabetics (n = 73). No correlation between adiponectin and inflammatory markers was found. Adiponectin levels were negatively correlated with BMI adjusting for age and diabetic status, and gender (beta = -0.200, P = 0.020; beta = -0.235, P = 0.004). CONCLUSIONS:No correlation exists between adiponectin and inflammatory markers. Adiponectin levels are lower in type 2 diabetic Trinidadians than in non-diabetics and decreases with increasing adiposity, using BMI as the marker.

journal_name

Arch Physiol Biochem

authors

Nayak S,Soon SQ,Kunjal R,Ramadoo R,Baptiste O,Persad J,Temull V,Diptee L,Balgobin S

doi

10.1080/13813450902758785

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

28-33

issue

1

eissn

1381-3455

issn

1744-4160

pii

909279030

journal_volume

115

pub_type

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