Abstract：
:The influence of ageing on the capacity to increase muscle oxygen delivery during exercise is unclear. This was investigated by comparing the evolution of Near InfraRed Spectroscopy (NIRS) in 10 old (67 +/- 5 years, Old group) and 13 young subjects (27 +/- 4 years, Young group), during a progressive maximal exercise. The NIRS probe was placed on the vastus lateralis; muscle oxygen saturation - IR-SmO(2) - values were expressed on a scale using an arterial occlusion as the lower reference point and the subsequent reactive hyperaemia as the upper reference point. Resting IR-SmO( 2) was found to be significantly lower in the Old as co mpared to the Young group. During exercise, VO(2) increased similarly as a function of the workload whereas IR-SmO(2) decreased faster in old subjects than in young ones. Conversely, when expressed at the same percentage of VO( 2max), IR-SmO(2) followed a similar evolution in both groups from rest to maximal exercise (27.3 +/- 16.7 vs 24.3 +/- 12.9% decrease, in Old and Young group, respectively, NS). Thus, the initial difference remained constant between the two groups. During recovery, the time to recover the signal variation was not different between the two groups. We concluded that Old subjects demonstrate a systematic lower muscle oxygen saturation than Young ones. This difference could be explained by an age related decrease in muscle blood flow limiting O(2) supply.
journal_name
Arch Physiol Biochemjournal_title
Archives of physiology and biochemistryauthors
Costes F,Denis C,Roche F,Prieur F,Enjolras F,Barthélémy JCdoi
10.1076/apab.107.2.159.4343subject
Has Abstractpub_date
1999-04-01 00:00:00pages
159-67issue
2eissn
1381-3455issn
1744-4160journal_volume
107pub_type
杂志文章abstract：:Adipose tissue is not only releasing lipids but also various adipokines that are both dysregulated in the obese state and may contribute to obesity-associated vascular dysfunction and cardiovascular risk. We have previously shown that the combination of adipocyte-conditioned medium (CM) and oleic acid (OA) increases p...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.3109/13813455.2015.1045520
更新日期：2015-01-01 00:00:00
abstract：:Objective: To evaluate the diagnostic and prognostic value of biomarkers and new bioscore in septic patients in intensive care unit (ICU).Materials and methods: A study was conducted on septic and non-septic patients in ICU. Diagnostic and prognostic values of C-reactive protein (CRP), procalcitonin (PCT), Sequential ...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2019.1677720
更新日期：2019-11-05 00:00:00
abstract：:In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to that occurring spontaneously. Eight mumol spermine were administered orally once a day, for one or three days, to su...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1076/apab.106.1.46.4392
更新日期：1998-02-01 00:00:00
abstract：CONTEXT:The views of type 2 diabetes (T2DM) patients have not been considered in the debate on the role of self-monitoring of blood glucose (SMBG) in the management of T2DM. OBJECTIVE:To assess the views of T2DM patients on SMBG. METHODS:Two previously trained research assistants used a structured pre-tested question...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.3109/13813455.2011.625950
更新日期：2012-02-01 00:00:00
abstract：:This study investigates the alcoholic extract effect of Alhagi camelorum on blood glucose and lipid profiles in diabetic rats made by streptozotocin (STZ). Male rats were divided into four groups. The control group received a normal diet. The diabetic group was induced by STZ and two diabetic experimental groups recei...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2019.1635623
更新日期：2019-08-04 00:00:00
abstract：:This study aimed to investigate the roles of RPSAP52 in renal failure. Our results showed that RPSAP52 was upregulated in plasma of renal failure patients in comparison to healthy controls. Dual luciferase reporter assay showed that RPSAP52 could interact with miR-423-5p, while overexpression of RPSAP52 and miR-423-5p...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1750657
更新日期：2020-04-17 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2018.1517181
更新日期：2020-07-01 00:00:00
abstract：:The effectiveness of betulinic acid (B) and PLGA loaded nanoparticles of B (Bnp) against hepatocellular carcinoma (HCC) was established and reported earlier. In continuation of our previous report, the present study described the molecular mechanisms of their antineoplastic responses. In this context, the antineoplast...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1733024
更新日期：2020-03-06 00:00:00
abstract：:Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.3109/13813455.2013.795175
更新日期：2013-10-01 00:00:00
abstract：:Diabetes represents an important public health problem. Recently, new molecular targets have been identified and exploited to treat this disease. Due to its pivotal role in glucose homeostasis, glucokinase (GCK) is a promising target for the development of novel antidiabetic drugs; however, pharmacological agents that...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2019.1627458
更新日期：2019-06-18 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.3109/13813455.2012.715651
更新日期：2012-12-01 00:00:00
abstract：:Background: Rheumatoid arthritis (RA) is a joint destructive disorder. This study aimed to assess lncRNA MEG3 expression and its variant rs941576 in Egyptian patients with RA.Subjects and methods: 100 RA patients and 100 healthy individuals were enrolled in the study. Quantitative PCR was used for expression analysis ...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1784951
更新日期：2020-07-01 00:00:00
abstract：:Background: We investigated whether the anti-inflammatory and antioxidant agent, resveratrol can inhibit type 2 diabetes mellitus (T2DM)-induced osteoarthritis (OA) in rats and whether it is associated with the suppression of glycaemia, dyslipidemia and inflammatory and oxidative stress biomarkers.Materials and method...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1771378
更新日期：2020-06-04 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1778036
更新日期：2020-07-13 00:00:00
abstract：:The actions of the insulin-like growth factor (IGF)-system are controlled by six IGF-binding proteins (IGFBPs). The IGFBPs are thought to affect local effects of IGF-I and IGF-II due to higher affinity if compared to IGF-I receptors and due to cell-type specific IGFBP expression patterns. It was found in IGFBP knockou...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.1080/13813450701531193
更新日期：2007-06-01 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2018.1437751
更新日期：2019-05-01 00:00:00
abstract：:It is known that oxidative stress plays an important role in the chronic complications of diabetes. Lipid peroxidation is one of the consequences of oxidative stress. Erythrocyte deformability abilities are reduced as a result of lipid peroxidation. Conversely, a decrease nitric oxide (NO) production seems to be respo...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.3109/13813455.2012.714790
更新日期：2012-12-01 00:00:00
abstract：AIM:To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians. METHODS:It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813450902758785
更新日期：2009-02-01 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2018.1494746
更新日期：2020-05-01 00:00:00
abstract：AIM:A high-fat diet (HFD) can lead to obesity and related metabolic disorders. This study evaluated the preventive efficacy of myricetin derivative-rich fraction (MD) from Syzygium malaccense leaf extract against HFD-induced obesity, hyperglycaemia, and oxidative stress in C57BL/6J mice. METHODS:HFD-fed mice were admi...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1808019
更新日期：2020-08-19 00:00:00
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journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.3109/13813455.2014.992440
更新日期：2015-05-01 00:00:00
abstract：:Diabetic cardiomyopathy consists of a series of structural and functional changes. Accumulating evidence supports the concept that a "cardiac stem cell compartment disease" plays an important role in the pathophysiology of diabetic cardiomyopathy. In diabetic hearts, human cardiac stem/progenitor cells (CSPC) are redu...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.3109/13813455.2013.798334
更新日期：2013-10-01 00:00:00
abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
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更新日期：2020-01-25 00:00:00
abstract：:Background: This study aimed to investigate the association of calorie and carbohydrate intake with tumour grade in early detection of breast cancer (BC) in Iranian women.Materials and methods: This case-control study carried out on 62 women with high grade BC and 93 women with low grade BC. Information about confound...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2020.1754430
更新日期：2020-05-06 00:00:00
abstract：:A total of 45 preruminant goats were fed either goat milk or a milk substitute. The postnatal development of bile secretion and biliary lipids composition of suckling goats and the influence upon these parameters of maternal milk substitution were studied during the first month of life. Samples of hepatic and gallblad...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1076/apab.104.2.239.12876
更新日期：1996-01-01 00:00:00
abstract：:The current in-vivo study was premeditated to uncover the protective role of ezetimibe (EZ) against advanced glycation endproducts (AGEs)-related pathologies in experimental diabetes. Our results showed that EZ markedly improved the altered biochemical markers of diabetes mellitus (DM) (FBG, HbA1c, insulin, microalbum...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2021.1874996
更新日期：2021-01-29 00:00:00
abstract：:Aims: Regarding the fact that up-regulation of miR-195 in diabetic hearts has a potential role in diabetic cardiomyopathy, the present study investigated whether continuous endurance training (CET) and high-intensity interval training (HIIT) reduces miR-195 expression and which exercise is effective in this regard.Met...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2018.1511599
更新日期：2020-07-01 00:00:00
abstract：:Pulmonary ischemia-reperfusion (IR) injury may result from trauma, atherosclerosis, pulmonary embolism, pulmonary thrombosis and surgical procedures such as cardiopulmonary bypass and lung transplantation. IR injury induces oxidative stress characterized by formation of reactive oxygen (ROS) and reactive nitrogen spec...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章,评审
doi：10.1080/13813450601118976
更新日期：2007-02-01 00:00:00
abstract：CONTEXT:The important role of exercise in pulmonary function during menopause is not well known. Oestrogen deficiency in ageing female mice is accompanied by increase in apoptotic markers such as caspase3 in the lung. OBJECTIVE:The present study was designed to investigate whether swimming training will ameliorate fib...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1080/13813455.2017.1396347
更新日期：2018-10-01 00:00:00
abstract：:Investigations were undertaken to obtain information on the mechanism by which orally administered spermine induces postnatal maturation in the rat intestine. Suckling rats ingested one dose of spermine (8 mumol) then were sacrificed at different intervals. -A. Proximal and distal parts of the intestine were homogenis...
journal_title：Archives of physiology and biochemistry
pub_type： 杂志文章
doi：10.1076/apab.104.2.163.12886
更新日期：1996-01-01 00:00:00
