Diagnostic and prognostic value of new bioscore in critically ill septic patients.

Abstract:

:Objective: To evaluate the diagnostic and prognostic value of biomarkers and new bioscore in septic patients in intensive care unit (ICU).Materials and methods: A study was conducted on septic and non-septic patients in ICU. Diagnostic and prognostic values of C-reactive protein (CRP), procalcitonin (PCT), Sequential Organ Failure Assessments (SOFA) score and new bioscore were analysed statistically.Results: A total of 226 patients were enrolled in the study. In septic patients, PCT, SOFA and bioscore were found significantly increased (p = .007, p = .001 and p = .001, respectively). The AUC value of bioscore was higher than PCT and SOFA in septic patients. SOFA was found to be more significant prognostic marker than bioscore in predicting 28-day mortality. The prognostic value of bioscore and SOFA was similar for predicting 90-day mortality.Conclusions: The new bioscore formed by combination of CRP, PCT and SOFA score may be useful in early diagnosis of sepsis.

journal_name

Arch Physiol Biochem

authors

Sen P,Demirdal T,Nemli SA,Sencan A

doi

10.1080/13813455.2019.1677720

subject

Has Abstract

pub_date

2019-11-05 00:00:00

pages

1-6

eissn

1381-3455

issn

1744-4160

pub_type

杂志文章
  • Looking at proteins from two dimensions: a review on five decades of 2D electrophoresis.

    abstract::Separating proteins according to two different gel-electrophoretic methods not only increases the resolution power for highly complex samples when compared to one-dimensional separations, but is also a valuable tool for protein and protein complex characterization. There are a number of different electrophoresis metho...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.3109/13813455.2014.945188

    authors: Westermeier R

    更新日期:2014-12-01 00:00:00

  • Associations between polymorphisms in VDR gene and the risk of osteoporosis: a meta-analysis.

    abstract::The authors conducted this meta-analysis to robustly estimate relationships between polymorphisms in VDR gene and the risk of osteoporosis by integrating the results of previous works. Medline, Embase, Wanfang, VIP and CNKI were searched thoroughly for eligible studies, and 73 genetic association studies were finally ...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1787457

    authors: Jiang LL,Zhang C,Zhang Y,Ma F,Guan Y

    更新日期:2020-08-06 00:00:00

  • Upregulation of the transport system for TNFalpha at the blood-brain barrier.

    abstract::The transport system for the cytokine tumor necrosis factor-alpha (TNFalpha) at the blood-brain barrier (BBB) enables an enhanced yet saturable entry of TNFalpha from blood to the CNS. This review focuses on the selective upregulation of the transport system for TNFalpha at the BBB that is specific for type of patholo...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.1076/apab.109.4.350.4238

    authors: Pan W,Kastin AJ

    更新日期:2001-10-01 00:00:00

  • Glucokinase activation as antidiabetic therapy: effect of nutraceuticals and phytochemicals on glucokinase gene expression and enzymatic activity.

    abstract::Diabetes represents an important public health problem. Recently, new molecular targets have been identified and exploited to treat this disease. Due to its pivotal role in glucose homeostasis, glucokinase (GCK) is a promising target for the development of novel antidiabetic drugs; however, pharmacological agents that...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2019.1627458

    authors: Guzmán TJ,Gurrola-Díaz CM

    更新日期:2019-06-18 00:00:00

  • The role of vasopressin V1A and oxytocin OTR receptors in protective effects of arginine vasopressin against H2O2-induced oxidative stress in H9C2 cells.

    abstract::Background: Oxidative stress, has been shown to play an important role in the pathophysiology of cardiac remodelling and heart failure. The aim of study is effect of arginine vasopressin (AVP) on apoptosis of cardiomyocyte via its receptors.Materials and methods: The cell viability effect of AVP in H9C2 cardiomyocytes...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1729816

    authors: Ghorbanzadeh V,Jafarpour A,Pirnia A,Pajouhi N,Khaksarian M,Veiskarami S,Nazari A

    更新日期:2020-03-06 00:00:00

  • Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies.

    abstract:BACKGROUND:A substantial body of evidence links sex hormones, diet, excess body weight and physical activity to the risk of developing cancer at several sites common in affluent countries. The hypothesis that high circulating levels of insulin could be the underlying factor increasing cancer risk has been proposed. Epi...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,meta分析

    doi:10.1080/13813450801954451

    authors: Pisani P

    更新日期:2008-02-01 00:00:00

  • Are folliculo-stellate cells in the anterior pituitary gland supportive cells or organ-specific stem cells?

    abstract::Folliculo-stellate cells (FS-cells) in the anterior pituitary gland are star-shaped cells and form tiny follicles. FS-cells are positive for S-100 protein and produce many cytokines or growth factors, such as interleukin-6 (IL-6), leukemia inhibitory factor (LIF), basic fibroblastic growth factor (bFGF) and vascular e...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.1076/apab.110.1.50.911

    authors: Inoue K,Mogi C,Ogawa S,Tomida M,Miyai S

    更新日期:2002-04-01 00:00:00

  • Nutritional programming of blood pressure and renal morphology.

    abstract::A range of epidemiological evidence from several diverse populations, supports the hypothesis that risk of essential hypertension, coronary heart disease and non-insulin dependent diabetes is, in part, programmed by intrauterine nutritional status. Animal models developed to investigate the mechanisms that are respons...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.1076/apab.111.1.8.15136

    authors: Langley-Evans SC,Langley-Evans AJ,Marchand MC

    更新日期:2003-02-01 00:00:00

  • Association of calorie and carbohydrate intake with tumour grade in early diagnosis of breast cancer: a case-control study.

    abstract::Background: This study aimed to investigate the association of calorie and carbohydrate intake with tumour grade in early detection of breast cancer (BC) in Iranian women.Materials and methods: This case-control study carried out on 62 women with high grade BC and 93 women with low grade BC. Information about confound...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1754430

    authors: Hatami M,Doaei S,Gholamalizadeh M,Mosavi Jarrahi SA,Mirsafa F,Davoodi SH

    更新日期:2020-05-06 00:00:00

  • New insights into the in vitro, in situ and in vivo antihyperglycemic mechanisms of gallic acid and p-coumaric acid.

    abstract::Objective: To explore the probable in vitro, in situ and in vivo mechanisms of gallic acid (GA) and p-coumaric acid (PCA) as anti-hyperglycemic agents.Animals and methods: Male albino rats were allocated into four groups, group1 was used as normal control. Group 2 was established as a diabetic control and group3 and 4...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1762659

    authors: Abdel-Moneim A,Abd El-Twab SM,Yousef AI,Ashour MB,Reheim ESA,Hamed MAA

    更新日期:2020-05-13 00:00:00

  • Protective effects of di- and tri-peptides containing proline, glycine, and leucine on liver enzymology and histopathology of diabetic mice.

    abstract::Context: Small peptides as multifunctional biomolecules can prevent the metabolic disorders such as diabetes. Objective: The purpose of this study was to investigate the effects of small peptides on the enzymes and histopathology of the liver in mice exposed to diabetes. Methods: Di- and tri-peptides containing prolin...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2019.1662453

    authors: Mesgari-Abbasi M,Valizadeh H,Mirzakhani N,Vahdatpour T

    更新日期:2019-09-09 00:00:00

  • Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa.

    abstract::We investigated the effects of tauroursodeoxycholic acid (TUDCA) to assess whether this acid may also have "protective" effects similar to those found with ursodeoxycholic acid (UDCA). We used a well-known amphibian model of gastric mucosa, and studied the effects of taurodeoxycholic acid (TDCA) on electrical transepi...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1076/apab.110.3.197.8295

    authors: Piepoli AL,Caroppo R,Armentano R,Caruso ML,Guerra V,Maselli MA

    更新日期:2002-07-01 00:00:00

  • Incretin hormones and beta-cell mass expansion: what we know and what is missing?

    abstract::Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.3109/13813455.2013.795175

    authors: Tortosa F,Dotta F

    更新日期:2013-10-01 00:00:00

  • Purine metabolites can indicate diabetes progression.

    abstract::Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2019.1663219

    authors: Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

    更新日期:2019-09-13 00:00:00

  • Folic acid increases levels of GHS in brain of rats with oxidative stress induced with 3-nitropropionic acid.

    abstract::Aim: This study tested the hypothesis that folic acid (FA) modulates biogenic amines and protects the brain against oxidative stress induced by 3-nitropropionic acid (3NPA).Methods: Male Wistar rats received (groups of six) for 5 d: FA (50 mg/kg); 3NPA (10 mg/kg); or FA +3NPA. At last day, rats were sacrificed, and th...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2018.1484771

    authors: Calderón Guzmán D,Osnaya Brizuela N,Ortiz Herrera M,Juárez Olguín H,Valenzuela Peraza A,Hernández García E,Barragán Mejía G

    更新日期:2020-02-01 00:00:00

  • LncRNA RPSAP52 regulates miR-423-5p/GSTM1 axis to suppress hypoxia-induced renal proximal tubular epithelial cell apoptosis.

    abstract::This study aimed to investigate the roles of RPSAP52 in renal failure. Our results showed that RPSAP52 was upregulated in plasma of renal failure patients in comparison to healthy controls. Dual luciferase reporter assay showed that RPSAP52 could interact with miR-423-5p, while overexpression of RPSAP52 and miR-423-5p...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1750657

    authors: Chen J,Zheng Y,Li L

    更新日期:2020-04-17 00:00:00

  • Exosomal expression of RAB27A and its related lncRNA Lnc-RNA-RP11-510M2 in lung cancer.

    abstract:OBJECTIVES:Examine the diagnostic role of serum exosomal RAB27A mRNA in lung cancer and evaluate the relation of LncRNAs to lung cancer in association to RAB27A mRNA in Egyptian population. METHODS:Exosomal RNA-based biomarkers RAB27A mRNA and Lnc-RNA-RP11-510M2.10 were selected based on bioinformatic methods, followe...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2020.1778036

    authors: Mohamed Gamal El-Din G,Ibrahim FK,Shehata HH,Osman NM,Abdel-Rahman OM,Ali M

    更新日期:2020-07-13 00:00:00

  • Liver microsomal phospholipid fatty acids behavior and its relationship to bilirubin UDP-glucuronyltransferase activity in bile duct ligated rats.

    abstract::Phospholipid fatty acid composition and bilirubin UDP-glucuronyltransferase activity from liver microsomal membrane were studied in normal and in bile duct ligated rats. Incubation of normal microsomes with 15 microM bilirubin (considered as physiological concentration) yielded 60% bilirubin diglucuronide; in 2 days p...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.3109/13813459509047136

    authors: Ouviña CB,Pavese CB,Lemberg A,Bengochea LA

    更新日期:1995-08-01 00:00:00

  • The role of autophagy and mitophagy in cancers.

    abstract::Autophagy is an important life phenomenon in eukaryotic cells. Its main role is to remove and degrade its damaged organelles and excess biological macromolecules, and use degradation products to provide energy and rebuild the cell structure, playing an important role in maintaining cell homeostasis and cell life activ...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2019.1675714

    authors: Xu HM,Hu F

    更新日期:2019-10-09 00:00:00

  • The effects of interval training on oxygen pulse and performance in supra-threshold runs.

    abstract::The aim of this study was to examine (i) the effects of a severe interval training period on oxygen pulse kinetics (O2-p, the ratio between VO2 and heart rate), and (ii) to study the consequences of these effects on the variation of performance (time to exhaustion) during severe runs. Seven athletes were tested before...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1076/apab.111.3.202.23455

    authors: Laffite LP,Mille-Hamard L,Koralsztein JP,Billat VL

    更新日期:2003-07-01 00:00:00

  • Spirulina effect on modulation of toxins provided by food, impact on hepatic and renal functions.

    abstract::Spirulina platensis, is an alga rich in phycocyanin (potent antioxidant), is effective in regulating the balance of oxidative stress. The objective of this study is to observe the impact of ingestion of a highly oxidised vegetable oil, by rats of Wistar strain. Finally, we observe the effect of Spirulina used as an an...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2018.1444059

    authors: Ould Amara-Leffad L,Ramdane H,Nekhoul K,Ouznadji A,Koceir EA

    更新日期:2019-05-01 00:00:00

  • Oxygen and differentiation status modulate the effect of X-ray irradiation on physiology and mitochondrial proteome of human neuroblastoma cells.

    abstract::Cytotoxic effects, including oxidative stress, of low linear energy transfer (LET)-ionizing radiation are often underestimated and studies of their mechanisms using cell culture models are widely conducted with cells cultivated at atmospheric oxygen that does not match its physiological levels in body tissues. Also, c...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2016.1218518

    authors: Džinić T,Hartwig S,Lehr S,Dencher NA

    更新日期:2016-12-01 00:00:00

  • Relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects.

    abstract:OBJECTIVE:To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects. METHODS:A retrospective case control study comprised of 1794 patient (740 males and 1054 females). RESULTS:The correlation was found for lipid profile with ...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.3109/13813455.2011.613482

    authors: Nayak BS,Maharaj N,Fatt LA,Legall G

    更新日期:2012-02-01 00:00:00

  • Differential effect of high-fat, high-sucrose and combined high-fat/high-sucrose diets consumption on fat accumulation, serum leptin and cardiac hypertrophy in rats.

    abstract::The consumption of high calorie-content diets is the first cause of obesity, probably the main health issue worldwide; however, the experimental evidences for evaluating the differential metabolic modifications of high-sucrose or high-fat diets are scare. We evaluated the metabolic outcomes of the obesity induced by t...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2018.1517181

    authors: Gómez-Crisóstomo NP,De la Cruz-Hernández EN,Méndez Méndez ER,Hernández-Landero MF,Camacho Liévano JU,Martínez-Abundis E

    更新日期:2020-07-01 00:00:00

  • Nutrient sensing, leptin and insulin action.

    abstract::The glucose-fatty acid cycle as proposed four decades ago by Randle suggests that insulin resistance develops in consequence of alterations of the metabolic pressure of lipids. The more recently published 'hexosamine pathway theory' and the 'malonyl-CoA hypothesis' depict insulin resistance as a consequence of an imba...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.1076/apab.109.1.38.4284

    authors: Ukropec J,Seböková E,Klimes I

    更新日期:2001-02-01 00:00:00

  • New lower cutoff for serum high sensitive C-reactive protein in obese women indicates the risk of metabolic syndrome.

    abstract::Objective, materials and methods: The aim of this cross-sectional study with a consecutive enrolment was to analyse the role of high sensitive C-reactive protein (hs-CRP) measurement in similarly obese patients with and without the metabolic syndrome (MS). Results: In total, 589 obese patients were screened, of whom 1...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2018.1434207

    authors: Kucharska A,Sawicka-Gutaj N,Owecki M

    更新日期:2019-02-01 00:00:00

  • Cardiopreventive effects of camel milk against carbon tetrachloride induced oxidative stress, biochemical and histological alterations in mice.

    abstract::The present study was designed to examine the preventive effects of camel milk (CM) against the toxic effects of acute exposure to carbon tetrachloride (CCl4) on the heart tissue of mice. Administration of a single dose of CCl4 caused cardio toxicity as monitored by an increase in lipid peroxidation (thiobarbituric ac...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2017.1395889

    authors: Hamed H,Gargouri M,Bellassoued K,Ghannoudi Z,Elfeki A,Gargouri A

    更新日期:2018-07-01 00:00:00

  • Cytoprotective effects of essential oil of Pinus halepensis L. against aspirin-induced toxicity in IEC-6 cells.

    abstract:CONTEXT:Essential oils from Pinus species have been reported to have various therapeutic properties. OBJECTIVE:This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. MATERIAL AND METHODS:Th...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1080/13813455.2017.1347689

    authors: Bouzenna H,Hfaiedh N,Bouaziz M,Giroux-Metges MA,Elfeki A,Talarmin H

    更新日期:2017-12-01 00:00:00

  • Effects of morphine and naloxone on glucose metabolism in uterine strips from ovariectomized and non-ovariectomized restricted diet rats.

    abstract::The effect of underfeeding over glucose metabolism in uteri isolated from ovariectomized and non-ovariectomized rats subjected to a restricted diet for 25 days (50% of the normal food intake), was studied. Underfeeding decreases (14)CO(2) formation from U(14) C-glucose in intact animal uteri. While in ovariectomized r...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1076/apab.108.5.422.4295

    authors: Campos ML,Casalino-Matsuda SM,Linares JA,Goldraij A

    更新日期:2000-12-01 00:00:00

  • Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions.

    abstract::Pulmonary ischemia-reperfusion (IR) injury may result from trauma, atherosclerosis, pulmonary embolism, pulmonary thrombosis and surgical procedures such as cardiopulmonary bypass and lung transplantation. IR injury induces oxidative stress characterized by formation of reactive oxygen (ROS) and reactive nitrogen spec...

    journal_title:Archives of physiology and biochemistry

    pub_type: 杂志文章,评审

    doi:10.1080/13813450601118976

    authors: Ovechkin AV,Lominadze D,Sedoris KC,Robinson TW,Tyagi SC,Roberts AM

    更新日期:2007-02-01 00:00:00