New insights into the in vitro, in situ and in vivo antihyperglycemic mechanisms of gallic acid and p-coumaric acid.

abstract：:To investigate the antidiabetic effect of isopulegol in high-fat diet (HFD)/streptozotocin (STZ)-induced diabetic rats. Animals were made diabetic by feeding HFD for 4 weeks followed by single intraperitoneal injection of STZ (35 mg/kg b.w.; 0.1 M citrate buffer; pH 4.0). Plasma insulin, haemoglobin and glycogen conte...

journal_title：Archives of physiology and biochemistry

authors： Kalaivani K,Sankaranarayanan C

更新日期：2019-07-10 00:00:00

abstract：:The early and late effects of alloxan-diabetes and insulin treatment on kinetic properties of mitochondrial FoF1 ATPase were examined. Diabetic state resulted in significant decrease in the activity while insulin treatment caused hyper-stimulation. In control animals the enzyme activity resolved in three kinetic compo...

journal_title：Archives of physiology and biochemistry

authors： Patel SP,Katyare SS

更新日期：2006-07-01 00:00:00

abstract：:A-4166, a phenylalanine derivative, is a hypoglycemic agent, which has been shown to improve blood glucose levels mainly due to the rapid and short term stimulation of insulin release. Nevertheless, a possible extrapancreatic action of A-4166 has not yet been investigated. Therefore, insulin action (euglycemic hyperin...

journal_title：Archives of physiology and biochemistry

authors： Klimes I,Mitková A,Gasperíková D,Ukropec J,Líska B,Bohov P,Stanek J,Seböková E

更新日期：1998-10-01 00:00:00

abstract：:This study aimed to investigate the roles of RPSAP52 in renal failure. Our results showed that RPSAP52 was upregulated in plasma of renal failure patients in comparison to healthy controls. Dual luciferase reporter assay showed that RPSAP52 could interact with miR-423-5p, while overexpression of RPSAP52 and miR-423-5p...

journal_title：Archives of physiology and biochemistry

authors： Chen J,Zheng Y,Li L

更新日期：2020-04-17 00:00:00

abstract：:Diabetes is associated with depression and anxiety symptoms. The current investigation was designed to explore the effect of melatonin on depressive and anxiety like-behaviours, oxidative stress, levels of AGE, RAGE and S100B in streptozotocin-induced diabetic rats. The animals were divided into four groups: Normoglyc...

journal_title：Archives of physiology and biochemistry

authors： Ergenc M,Ozacmak HS,Turan I,Ozacmak VH

更新日期：2019-11-15 00:00:00

abstract：AIMS AND BACKGROUND:Obesity is recognised as a significant public health burden worldwide. Recently the cross-talk between gut microbiota and obesity has attracted much attention. To that end, Akkermansia muciniphila has been proposed as a promising microbe to manage obesity. In the present systematic review, we evalua...

journal_title：Archives of physiology and biochemistry

authors： Roshanravan N,Bastani S,Tutunchi H,Kafil B,Nikpayam O,Mesri Alamdari N,Hadi A,Sotoudeh S,Ghaffari S,Ostadrahimi A

更新日期：2021-01-15 00:00:00

abstract：:The present studies were conducted to examine the fatty acid composition of microsomal lipids of bovine small intestine. Microsomes and cytosol were isolated from mucosal scrapings enriched with villus and crypts cells, and the following studies were conducted to: 1) analyse fatty acids from microsomal lipids; 2) inco...

journal_title：Archives of physiology and biochemistry

authors： Furlan L,Catala A

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects. METHODS:A retrospective case control study comprised of 1794 patient (740 males and 1054 females). RESULTS:The correlation was found for lipid profile with ...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Maharaj N,Fatt LA,Legall G

更新日期：2012-02-01 00:00:00

abstract：:An enhanced luminescence technique was used to monitor the response of liver homogenates stressed with sodium perborate. Rat liver homogenates were subjected to oxidative stress with sodium perborate, and the light signals, generated by a suitable system, containing luminol and compounds producing enhancement of light...

journal_title：Archives of physiology and biochemistry

authors： Di Meo S,Venditti P,Piro MC,De Leo T

更新日期：1995-05-01 00:00:00

abstract：:In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to that occurring spontaneously. Eight mumol spermine were administered orally once a day, for one or three days, to su...

journal_title：Archives of physiology and biochemistry

authors： Peulen O,Pirlet C,Klimek M,Goffinet G,Dandrifosse G

更新日期：1998-02-01 00:00:00

abstract：:In the last decade proteomics has made great progress reaching throughput and comprehensiveness comparable to genomics technologies. Mass spectrometry plays a key role in proteomics and has become an indispensable method for molecular and cellular biology because many cellular changes in response to internal or extern...

journal_title：Archives of physiology and biochemistry

authors： Fröbel J,Lehr S,Haas R,Czibere A

更新日期：2009-12-01 00:00:00

abstract：:Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...

journal_title：Archives of physiology and biochemistry

authors： Tortosa F,Dotta F

更新日期：2013-10-01 00:00:00

abstract：:The spatial disparity sensitivity of single units in the primary visual cortex (17-18 border), in extrastriate area 19 and in the superficial layers of the superior colliculus of the cat brain were compared in the present study. Unit recordings were performed in paralyzed and anesthetized animals. Centrally located re...

journal_title：Archives of physiology and biochemistry

authors： Bacon BA,Lepore F,Guillemot JP

更新日期：1998-07-01 00:00:00

abstract：:Aim: This study designated to investigate and compare the therapeutic effect of Ulva lactuca methanolic extract against oxidative stress (OS)-infertility induced by naturally occurring prooxidants (gossypol) and selenium- vitamins A, C, and E (selenium-ACE) drug. Methods: Male infertility was induced in rat by intrape...

journal_title：Archives of physiology and biochemistry

authors： Ghareeb DA,Abd-Elgwad A,El-Guindy N,Yacout G,Zaatout HH

更新日期：2019-07-31 00:00:00

abstract：:Combining samples from a national neonatal screening programme with the information from a national health registry allow for unique opportunities in analysing newborn blood for protein changes that could predict eventual disease development. A nested case-control cohort (n = 54 cases, 108 controls) was analysed by pr...

journal_title：Archives of physiology and biochemistry

authors： McGuire JN,Eising S,Wägner AM,Pociot F

更新日期：2010-10-01 00:00:00

abstract：:Context: Exposure to Electomagnetic radiation fields of cell phones causes thyroid dysfunction and a previous study revealed that nesfatin-1 may affect functions of the thyroid gland.Objective: To study the role of nesfatin-1 on functions of rat's thyroid gland exposed to EMRF.Materials and methods: Thirty adult male ...

journal_title：Archives of physiology and biochemistry

authors： Hussien NI,Mousa AM,Shoman AA

更新日期：2020-06-17 00:00:00

abstract：:Changes in body fluid distribution are known to influence neuroendocrine function. The aim of the present study was to test the hypothesis that changes in plasma volume affect the counterregulatory neuroendocrine response to hypoglycemia. The tests were performed in 12 subjects in two situations: 'head-up' (+60 degree...

journal_title：Archives of physiology and biochemistry

authors： Radikova Z,Penesova A,Jezova D,Kvetnansky R,Vigas M,Macho L,Koska J

更新日期：2003-10-01 00:00:00

abstract：:It is known that oxidative stress plays an important role in the chronic complications of diabetes. Lipid peroxidation is one of the consequences of oxidative stress. Erythrocyte deformability abilities are reduced as a result of lipid peroxidation. Conversely, a decrease nitric oxide (NO) production seems to be respo...

journal_title：Archives of physiology and biochemistry

authors： Yapislar H,Aydogan S

更新日期：2012-12-01 00:00:00

abstract：:Aims: Regarding the fact that up-regulation of miR-195 in diabetic hearts has a potential role in diabetic cardiomyopathy, the present study investigated whether continuous endurance training (CET) and high-intensity interval training (HIIT) reduces miR-195 expression and which exercise is effective in this regard.Met...

journal_title：Archives of physiology and biochemistry

authors： Khakdan S,Delfan M,Heydarpour Meymeh M,Kazerouni F,Ghaedi H,Shanaki M,Kalaki-Jouybari F,Gorgani-Firuzjaee S,Rahimipour A

更新日期：2020-07-01 00:00:00

abstract：:Type 2 Diabetes mellitus (T2D) is the most common endocrine disorder associated to metabolic syndrome (MS) and occurs when insulin secretion can no compensate peripheral insulin resistance. Among peripheral tissues, the liver controls glucose homeostasis due to its ability to consume and produce glucose. The molecular...

journal_title：Archives of physiology and biochemistry

authors： Valverde AM,González-Rodríguez A

更新日期：2011-07-01 00:00:00

abstract：:This present study investigated the antioxidative and antidiabetic properties of kolaviron by analysing its inhibitory effect on key metabolic activities linked to T2D, in vitro and ex vivo. Kolaviron significantly inhibited α-glucosidase and α-amylase activities, and intestinal glucose absorption dose-dependently, wh...

journal_title：Archives of physiology and biochemistry

authors： Salau VF,Erukainure OL,Koorbanally NA,Islam MS

更新日期：2020-08-17 00:00:00

abstract：:An accumulating body of evidence supports the role of autophagy in the pathophysiology of T2DM. Also, abnormal endoplasmic reticulum (ER) stress response that has been implicated as a cause of insulin resistance (IR) could also be affected by the autophagic status in β-cells. The present study was designed to investig...

journal_title：Archives of physiology and biochemistry

authors： Gadallah SH,Ghanem HM,Abdel-Ghaffar A,Metwaly FG,Hanafy LK,Ahmed EK

更新日期：2019-06-19 00:00:00

abstract：:In the suckling and adult rats equilibrated or no by 125I, cutaneous iodine analysed by dialysis and chromatography techniques (Dowex and Sephadex) was the purpose of this study. Dialysis studies had shown that most of steady or labelled skin iodine had an iodide form (90 to 95% of the total iodine). There were at lea...

journal_title：Archives of physiology and biochemistry

authors： Zeghal N,Redjem M,Gondran F,Vigouroux E

更新日期：1995-08-01 00:00:00

abstract：CONTEXT:Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. OBJECTIVE:To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. MATERIALS AND METHODS:Rats were divided into control, sham, sham + ghreli...

journal_title：Archives of physiology and biochemistry

authors： Eid RA,Alkhateeb MA,Al-Shraim M,Eleawa SM,Shatoor AS,El-Kott AF,Zaki MSA,Shatoor KA,Bin-Jaliah I,Al-Hashem FH

更新日期：2019-05-01 00:00:00

abstract：:This study investigated the effects of garlic on anxiety- and depression-related behaviors and brain oxidative markers in streptozotocin (STZ)-induced diabetes in rats. Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8/group): control, diabetic + saline, diabetic + garlic, diabetic...

journal_title：Archives of physiology and biochemistry

authors： Rahmani G,Farajdokht F,Mohaddes G,Babri S,Ebrahimi V,Ebrahimi H

更新日期：2020-05-01 00:00:00

abstract：:Objective: We aimed to determine myo-inositol oxygenase (MIOX) activity in gestational diabetes mellitus (GDM).Material and Methods: The insulin, HbA1c, and MIOX levels of 80 pregnant women were analysed after 75 g OGTT. Group I included patients with no risk factor for GDM, Group II: patients with high risk for GDM, ...

journal_title：Archives of physiology and biochemistry

authors： Kısa B,Sert UY,Celik HK,Candar T,Erol Koç EM,Taşcı Y,Çağlar GS

更新日期：2020-03-19 00:00:00

abstract：:The objective of the study was to investigate the association of blood glucose and lipid profile parameters with cognitive impairment in schizophrenia. A total of 200 schizophrenia patients and 169 controls were enrolled in the study. Blood glucose and lipid profile were estimated in all the subjects. Cognition was as...

journal_title：Archives of physiology and biochemistry

authors： Nandeesha H,Keshri N,Rajappa M,Menon V

更新日期：2020-11-03 00:00:00

abstract：:Objectives: The main aim of this study was to investigate the effects of irisin on asprosin, leptin, glucose levels and lipid profile in healthy and obese male and female rats.Methods: Irisin was subcutaneously administered with osmotic minipumps at the dose of 100 ng/kg/day for 28 days and then, the serum levels of a...

journal_title：Archives of physiology and biochemistry

authors： Ozcan S,Ulker N,Bulmus O,Yardimci A,Ozcan M,Canpolat S

更新日期：2020-02-06 00:00:00

abstract：CONTEXT:Cardiometabolic disorders are rapidly becoming major public health challenges. Valproic acid (VPA) is a widely prescribed anticonvulsant drug. OBJECTIVE:We hypothesized that treatment with VPA would improve the regulation of glucose and atherogenic dyslipidemia through reduction in circulating corticosterone. ...

journal_title：Archives of physiology and biochemistry

authors： Olatunji LA,Omolekulo TE,Usman TO,Kim I

更新日期：2016-07-01 00:00:00

abstract：:The actions of the insulin-like growth factor (IGF)-system are controlled by six IGF-binding proteins (IGFBPs). The IGFBPs are thought to affect local effects of IGF-I and IGF-II due to higher affinity if compared to IGF-I receptors and due to cell-type specific IGFBP expression patterns. It was found in IGFBP knockou...

journal_title：Archives of physiology and biochemistry

authors： Hoeflich A,Götz W,Lichanska AM,Bielohuby M,Tönshoff B,Kiepe D

更新日期：2007-06-01 00:00:00