Screening newborns for candidate biomarkers of type 1 diabetes.

abstract：CONTEXT:Cardiometabolic disorders are rapidly becoming major public health challenges. Valproic acid (VPA) is a widely prescribed anticonvulsant drug. OBJECTIVE:We hypothesized that treatment with VPA would improve the regulation of glucose and atherogenic dyslipidemia through reduction in circulating corticosterone. ...

journal_title：Archives of physiology and biochemistry

authors： Olatunji LA,Omolekulo TE,Usman TO,Kim I

更新日期：2016-07-01 00:00:00

abstract：:An experiment in which the rats access either to 0.5% or 1.5% saline was designed in order to further characterise the relationship between sodium intake and renal excretion after acute immobilization stress. A saline solution for 3 days was provided to the rats previous to the experimental day. On that day, after fin...

journal_title：Archives of physiology and biochemistry

authors： Niebylski A,Bertuzzi M,Bensi N,Armario A,Gauna HF

更新日期：2000-07-01 00:00:00

abstract：:Glycogen synthesis increases after muscle contraction and during insulin stimulation, and insulin-stimulated glycogen synthesis is enhanced after contraction. We hypothesized that the initial glycogen content influences the magnitude of additive effect of contraction on insulin-stimulated glycogen synthesis. Contracti...

journal_title：Archives of physiology and biochemistry

authors： Lai YC,Stuenaes JT,Kuo CH,Jensen J

更新日期：2010-07-01 00:00:00

abstract：:The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or reproduction are well known; however, the interactions between these hormones remain unclear, especially in humans. The aim of this study was to determine the roles of leptin, nesfatin-1 and kisspeptin in pre- and postmenopausal obe...

journal_title：Archives of physiology and biochemistry

authors： Çelik F,Belviranli M,Okudan N

更新日期：2016-10-01 00:00:00

abstract：:In the last decade proteomics has made great progress reaching throughput and comprehensiveness comparable to genomics technologies. Mass spectrometry plays a key role in proteomics and has become an indispensable method for molecular and cellular biology because many cellular changes in response to internal or extern...

journal_title：Archives of physiology and biochemistry

authors： Fröbel J,Lehr S,Haas R,Czibere A

更新日期：2009-12-01 00:00:00

abstract：:In this study, we report the synthesis of novel tris-chalcones and testing of human carbonic anhydrase I, and II isoenzymes (hCA I, and hCA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase (α-Gly) inhibitors for the development of novel chalcone structures towards for treatment of some...

journal_title：Archives of physiology and biochemistry

authors： Burmaoglu S,Yilmaz AO,Polat MF,Kaya R,Gulcin İ,Algul O

更新日期：2019-06-07 00:00:00

abstract：:From the first report that bone marrow cells (BMC) have stem cells characteristics, several studies have debated the possibility of intervening in myocardial remodeling after injury, for example myocardial infarction, by using BMC. The goal of this paper is to review the concept of whether the demethylating agent 5-az...

journal_title：Archives of physiology and biochemistry

authors： Burlacu A

更新日期：2006-10-01 00:00:00

abstract：CONTEXT:Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. OBJECTIVE:To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. MATERIALS AND METHODS:Rats were divided into control, sham, sham + ghreli...

journal_title：Archives of physiology and biochemistry

authors： Eid RA,Alkhateeb MA,Al-Shraim M,Eleawa SM,Shatoor AS,El-Kott AF,Zaki MSA,Shatoor KA,Bin-Jaliah I,Al-Hashem FH

更新日期：2019-05-01 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:This study was to investigate whether epidermal growth factor (EGF) may induce any long-term effect on pancreatic exocrine function in vivo as well to evaluate the chronic effects of EGF on pancreatic growth in rats. Rats were treated with EGF (10 micrograms/kg) for 5 or 7 days. EGF infused intravenously (2 micrograms...

journal_title：Archives of physiology and biochemistry

authors： Lajas AI,Pozo MJ,Salido GM,Singh J,Pariente JA

更新日期：1996-01-01 00:00:00

abstract：CONTEXT:Vanillin is known to possess important antioxidant activity. OBJECTIVE:The current study was conducted to establish the therapeutic efficiency of vanillin against potassium bromate (KBrO3)-induced depression-like behavior and oxidative stress in mice. MATERIAL AND METHODS:Mice were exposed during 15 days eith...

journal_title：Archives of physiology and biochemistry

authors： Ben Saad H,Kharrat N,Driss D,Gargouri M,Marrakchi R,Jammoussi K,Magné C,Boudawara T,Ellouz Chaabouni S,Zeghal KM,Hakim A,Ben Amara I

更新日期：2017-07-01 00:00:00

abstract：:The present study was designed to examine the preventive effects of camel milk (CM) against the toxic effects of acute exposure to carbon tetrachloride (CCl4) on the heart tissue of mice. Administration of a single dose of CCl4 caused cardio toxicity as monitored by an increase in lipid peroxidation (thiobarbituric ac...

journal_title：Archives of physiology and biochemistry

authors： Hamed H,Gargouri M,Bellassoued K,Ghannoudi Z,Elfeki A,Gargouri A

更新日期：2018-07-01 00:00:00

abstract：CONTEXT:The important role of exercise in pulmonary function during menopause is not well known. Oestrogen deficiency in ageing female mice is accompanied by increase in apoptotic markers such as caspase3 in the lung. OBJECTIVE:The present study was designed to investigate whether swimming training will ameliorate fib...

journal_title：Archives of physiology and biochemistry

authors： Daghigh F,Alihemmati A,Karimi P,Habibi P,Ahmadiasl N

更新日期：2018-10-01 00:00:00

abstract：:Aim: This study tested the hypothesis that folic acid (FA) modulates biogenic amines and protects the brain against oxidative stress induced by 3-nitropropionic acid (3NPA).Methods: Male Wistar rats received (groups of six) for 5 d: FA (50 mg/kg); 3NPA (10 mg/kg); or FA +3NPA. At last day, rats were sacrificed, and th...

journal_title：Archives of physiology and biochemistry

authors： Calderón Guzmán D,Osnaya Brizuela N,Ortiz Herrera M,Juárez Olguín H,Valenzuela Peraza A,Hernández García E,Barragán Mejía G

更新日期：2020-02-01 00:00:00

abstract：:Study was carried out an Wistar female rats to evaluate the consequences of ovariectomy and 17 beta-estradiol substitutive treatment during aging on bone. Ca metabolism and calciotropic hormones. Three groups of fifteen rats, mature, old and senescent (4-, 10-, and 28 month-old) female were fed a diet (6 g/100 g BW/da...

journal_title：Archives of physiology and biochemistry

authors： Gaumet N,Seibel MJ,Coxam V,Davicco MJ,Lebecque P,Barlet JP

更新日期：1997-09-01 00:00:00

abstract：:Diabetes is associated with depression and anxiety symptoms. The current investigation was designed to explore the effect of melatonin on depressive and anxiety like-behaviours, oxidative stress, levels of AGE, RAGE and S100B in streptozotocin-induced diabetic rats. The animals were divided into four groups: Normoglyc...

journal_title：Archives of physiology and biochemistry

authors： Ergenc M,Ozacmak HS,Turan I,Ozacmak VH

更新日期：2019-11-15 00:00:00

abstract：CONTEXT:Glucose-6-phosphate dehydrogenase (G6PD) is an important enzyme of hexose monophosphate shunt, involved in the biosynthesis of reduced nicotinamide adenine dinucleotide phosphate hydrogen (NADPH). OBJECTIVE:This study was designed to investigate age-dependent changes in human erythrocyte G6PD activity. The G6P...

journal_title：Archives of physiology and biochemistry

authors： Maurya PK,Kumar P,Chandra P

更新日期：2016-01-01 00:00:00

abstract：:This present study investigated the antioxidative and antidiabetic properties of kolaviron by analysing its inhibitory effect on key metabolic activities linked to T2D, in vitro and ex vivo. Kolaviron significantly inhibited α-glucosidase and α-amylase activities, and intestinal glucose absorption dose-dependently, wh...

journal_title：Archives of physiology and biochemistry

authors： Salau VF,Erukainure OL,Koorbanally NA,Islam MS

更新日期：2020-08-17 00:00:00

abstract：:Diabetes mellitus, especially when complicated with decline of renal function due to diabetic nephropathy (DN), is associated with accumulation of advanced glycation end products (AGEs) exerting their adverse effects via receptor of AGE (RAGE). Soluble RAGE (sRAGE) is a truncated form of RAGE functioning as an inhibit...

journal_title：Archives of physiology and biochemistry

authors： Kanková K,Kalousová M,Hertlová M,Krusová D,Olsovský J,Zima T

更新日期：2008-04-01 00:00:00

abstract：:The authors conducted this meta-analysis to robustly estimate relationships between polymorphisms in VDR gene and the risk of osteoporosis by integrating the results of previous works. Medline, Embase, Wanfang, VIP and CNKI were searched thoroughly for eligible studies, and 73 genetic association studies were finally ...

journal_title：Archives of physiology and biochemistry

authors： Jiang LL,Zhang C,Zhang Y,Ma F,Guan Y

更新日期：2020-08-06 00:00:00

abstract：:Aims: Regarding the fact that up-regulation of miR-195 in diabetic hearts has a potential role in diabetic cardiomyopathy, the present study investigated whether continuous endurance training (CET) and high-intensity interval training (HIIT) reduces miR-195 expression and which exercise is effective in this regard.Met...

journal_title：Archives of physiology and biochemistry

authors： Khakdan S,Delfan M,Heydarpour Meymeh M,Kazerouni F,Ghaedi H,Shanaki M,Kalaki-Jouybari F,Gorgani-Firuzjaee S,Rahimipour A

更新日期：2020-07-01 00:00:00

abstract：:Background: We investigated whether the anti-inflammatory and antioxidant agent, resveratrol can inhibit type 2 diabetes mellitus (T2DM)-induced osteoarthritis (OA) in rats and whether it is associated with the suppression of glycaemia, dyslipidemia and inflammatory and oxidative stress biomarkers.Materials and method...

journal_title：Archives of physiology and biochemistry

authors： Ebrahim HA,Alzamil NM,Al-Ani B,Haidara MA,Kamar SS,Dawood AF

更新日期：2020-06-04 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the devastating complications in diabetes mellitus (DM). Glucagon-like peptide-1 (GLP-1) is one of the incretins secreted from L cells in the intestine. Crocin (a carotenoid component of saffron) has antioxidants properties. We investigated the renal effects of Exendin-4 as a GLP-1 ...

journal_title：Archives of physiology and biochemistry

authors： Amin SN,El-Gamal EM,Rashed LA,Kamar SS,Haroun MA

更新日期：2020-12-07 00:00:00

abstract：:Separating proteins according to two different gel-electrophoretic methods not only increases the resolution power for highly complex samples when compared to one-dimensional separations, but is also a valuable tool for protein and protein complex characterization. There are a number of different electrophoresis metho...

journal_title：Archives of physiology and biochemistry

authors： Westermeier R

更新日期：2014-12-01 00:00:00

abstract：:Changes in body fluid distribution are known to influence neuroendocrine function. The aim of the present study was to test the hypothesis that changes in plasma volume affect the counterregulatory neuroendocrine response to hypoglycemia. The tests were performed in 12 subjects in two situations: 'head-up' (+60 degree...

journal_title：Archives of physiology and biochemistry

authors： Radikova Z,Penesova A,Jezova D,Kvetnansky R,Vigas M,Macho L,Koska J

更新日期：2003-10-01 00:00:00

abstract：:Hepatotoxicity, induced by aluminium chloride (AlCl3), has been well studied but there are no reports about liver metallothionein (MT) genes induction. Therefore, it is of interest to establish the mechanism involving the relation between MT gene expression levels and the oxidative stress status in hepatic cells of al...

journal_title：Archives of physiology and biochemistry

authors： Ghorbel I,Chaabane M,Elwej A,Boudawara O,Abdelhedi S,Jamoussi K,Boudawara T,Zeghal N

更新日期：2016-10-01 00:00:00

abstract：:Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in...

journal_title：Archives of physiology and biochemistry

authors： Hosseini SA,Hamzavi K,Safarzadeh H,Salehi O

更新日期：2020-10-05 00:00:00

abstract：:An accumulating body of evidence supports the role of autophagy in the pathophysiology of T2DM. Also, abnormal endoplasmic reticulum (ER) stress response that has been implicated as a cause of insulin resistance (IR) could also be affected by the autophagic status in β-cells. The present study was designed to investig...

journal_title：Archives of physiology and biochemistry

authors： Gadallah SH,Ghanem HM,Abdel-Ghaffar A,Metwaly FG,Hanafy LK,Ahmed EK

更新日期：2019-06-19 00:00:00

abstract：:Since the first systematic analysis concerning the functional properties of mechanoreceptors in the glabrous skin of the human hand was made in 1970, the amount of available data has grown tremendously. Whereas the first research in the seventies was aimed at achieving a standard functional description of the mechanor...

journal_title：Archives of physiology and biochemistry

authors： Pasterkamp E

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:To determine the awareness of HbA1c values and correlate this with educational levels, dietary intake and physical activity in type II diabetic population of Trinidad. METHODS:Total of 222 type II diabetic subjects were assessed via questionnaire evaluating their demographics, type and duration of diabetes,...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Khan K,Kidney C,Knowles V,Koo A,Lakhan A,Lalla D,Lalloo C,Lallo SA,Singh S

更新日期：2018-12-01 00:00:00