Spermatogenesis and steroidogenesis disruption in a model of metabolic syndrome rats.

abstract：INTRODUCTION:Insulin resistance (IR) is closely associated with increased atherogenic risk. OBJECTIVE:To investigate leptin, adiponectin, soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1) levels and their relationship with each other and metabolic parameters in wo...

journal_title：Archives of physiology and biochemistry

authors： Koleva DI,Orbetzova MM,Nikolova JG,Tyutyundzhiev SB

更新日期：2016-10-01 00:00:00

abstract：:Pancreatic beta-cell mass expands through beta-cell proliferation and neogenesis while it decreases mainly via apoptosis. The loss of balance between beta-cell death and regeneration leads to a reduction of beta-cell functional mass, thus contributing to the pathogenesis of type 2 diabetes mellitus (T2DM). The pathoge...

journal_title：Archives of physiology and biochemistry

authors： Tortosa F,Dotta F

更新日期：2013-10-01 00:00:00

abstract：:The current in-vivo study was premeditated to uncover the protective role of ezetimibe (EZ) against advanced glycation endproducts (AGEs)-related pathologies in experimental diabetes. Our results showed that EZ markedly improved the altered biochemical markers of diabetes mellitus (DM) (FBG, HbA1c, insulin, microalbum...

journal_title：Archives of physiology and biochemistry

authors： Nabi R,Alvi SS,Shah A,Chaturvedi CP,Faisal M,Alatar AA,Ahmad S,Khan MS

更新日期：2021-01-29 00:00:00

abstract：:Context: Follistatin-like 1 (FSTL1) and apelin exert a favourable effect on energy metabolism.Objective: We examined the effects of acute endurance exercise on the levels of FSTL1 and apelin in the serum and metabolic organs of rats.Methods: Rats were divided into two groups: a sedentary control (CON, n = 8) group and...

journal_title：Archives of physiology and biochemistry

authors： Kon M,Tanimura Y,Yoshizato H

更新日期：2020-05-15 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:Investigations were undertaken to obtain information on the mechanism by which orally administered spermine induces postnatal maturation in the rat intestine. Suckling rats ingested one dose of spermine (8 mumol) then were sacrificed at different intervals. -A. Proximal and distal parts of the intestine were homogenis...

journal_title：Archives of physiology and biochemistry

authors： Wéry I,Deloyer P,Dandrifosse G

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:The potentially beneficial effects of pomegranate peel (PPE), flower (PFE) and seed oil (PSO) extracts, in comparison with rosiglitazone, on adiposity, lipid profile, glucose homoeostasis, as well as on the underlying inflammatory mechanisms, were examined in high-fat and high-sucrose (HF/HS) diet-induced obe...

journal_title：Archives of physiology and biochemistry

authors： Harzallah A,Hammami M,Kępczyńska MA,Hislop DC,Arch JR,Cawthorne MA,Zaibi MS

更新日期：2016-01-01 00:00:00

abstract：:Pulmonary ischemia-reperfusion (IR) injury may result from trauma, atherosclerosis, pulmonary embolism, pulmonary thrombosis and surgical procedures such as cardiopulmonary bypass and lung transplantation. IR injury induces oxidative stress characterized by formation of reactive oxygen (ROS) and reactive nitrogen spec...

journal_title：Archives of physiology and biochemistry

authors： Ovechkin AV,Lominadze D,Sedoris KC,Robinson TW,Tyagi SC,Roberts AM

更新日期：2007-02-01 00:00:00

abstract：:Background: Rheumatoid arthritis (RA) is a joint destructive disorder. This study aimed to assess lncRNA MEG3 expression and its variant rs941576 in Egyptian patients with RA.Subjects and methods: 100 RA patients and 100 healthy individuals were enrolled in the study. Quantitative PCR was used for expression analysis ...

journal_title：Archives of physiology and biochemistry

authors： Wahba AS,Ibrahim ME,Mesbah NM,Saleh SM,Abo-Elmatty DM,Mehanna ET

更新日期：2020-07-01 00:00:00

abstract：:Context: The anti-diabetic medicine metformin has been reported as an anti-ageing drug candidate as it mimics the benefits of caloric restriction and reduces ageing-related oxidative stress in various experimental organisms. Objective: We investigated the possible anti-oxidative role of metformin against rotenone-indu...

journal_title：Archives of physiology and biochemistry

authors： Tripathi SS,Singh AK,Akhtar F,Chaudhary A,Rizvi SI

更新日期：2019-06-01 00:00:00

abstract：:The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or reproduction are well known; however, the interactions between these hormones remain unclear, especially in humans. The aim of this study was to determine the roles of leptin, nesfatin-1 and kisspeptin in pre- and postmenopausal obe...

journal_title：Archives of physiology and biochemistry

authors： Çelik F,Belviranli M,Okudan N

更新日期：2016-10-01 00:00:00

abstract：:Stimulation of cellular fatty acid uptake by induction of insulin signalling or AMP-kinase (AMPK) activation is due to translocation of the fatty acid-transporter CD36 from intracellular stores to the plasma membrane (PM). For investigating the role of the four Cys-residues within CD36's cytoplasmic tails in CD36 tran...

journal_title：Archives of physiology and biochemistry

authors： van Oort MM,Drost R,Janβen L,Van Doorn JM,Kerver J,Van der Horst DJ,Luiken JJ,Rodenburg KC

更新日期：2014-02-01 00:00:00

abstract：:The present study aimed to evaluate the relationship between exercise and both l-tyrosine and oxidative stress using thiol/disulphide homeostasis via a novel biomarker in rats. Following the completion of the exercise and l-tyrosine protocol, serum total thiol, native thiol, and disulphide concentrations were determin...

journal_title：Archives of physiology and biochemistry

authors： Kayacan Y,Yazar H,Kisa EC,Ghojebeigloo BE

更新日期：2018-07-01 00:00:00

abstract：:Combining samples from a national neonatal screening programme with the information from a national health registry allow for unique opportunities in analysing newborn blood for protein changes that could predict eventual disease development. A nested case-control cohort (n = 54 cases, 108 controls) was analysed by pr...

journal_title：Archives of physiology and biochemistry

authors： McGuire JN,Eising S,Wägner AM,Pociot F

更新日期：2010-10-01 00:00:00

abstract：:Due to the importance of zinc as an antioxidant and its crucial role in insulin synthesis, its deficiency may affect adversely diabetic state. So, this study aimed to modulate these effects using Curcuma longa as natural antioxidant. Rats were divided into four groups: two groups fed a zinc sufficient diet one non-dia...

journal_title：Archives of physiology and biochemistry

authors： Tebboub I,Kechrid Z

更新日期：2019-06-19 00:00:00

abstract：:This study investigates the alcoholic extract effect of Alhagi camelorum on blood glucose and lipid profiles in diabetic rats made by streptozotocin (STZ). Male rats were divided into four groups. The control group received a normal diet. The diabetic group was induced by STZ and two diabetic experimental groups recei...

journal_title：Archives of physiology and biochemistry

authors： Nabiyouni F,Vaezi G,Malekirad AA

更新日期：2019-08-04 00:00:00

abstract：:Antisense oligonucleotides (ODN) are potent molecules that could be used to inhibit the synthesis of a protein specifically if delivered to the appropriate compartments (cytoplasm and nucleus) of the cell under study. We present here a simple method providing access to the fractions of internalized ODN available in th...

journal_title：Archives of physiology and biochemistry

authors： Eboue D,Auger R,Angiari C,Le Doan T,Tenu JP

更新日期：2003-07-01 00:00:00

abstract：AIM:The objective of this study was to evaluate the probable mechanism of action of Biochanin A (BCA) on high-fat diet-induced insulin resistance mice. METHODS:Twenty-four male C57/BL/6J mice were divided into two and fed either control diet or a high fat-high diet (HFD). After 6 weeks, mice were grouped into: Control...

journal_title：Archives of physiology and biochemistry

authors： Arjunan S,Thangaiyan R,Balaraman D

更新日期：2020-09-29 00:00:00

abstract：:The mechanism underlying the increased rate of endogenous glucose production from the liver during exercise remains unknown. The cytokine interleukin-6 (IL-6) is known to be released during exercise and is thought that either IL-6 directly or via a "contraction factor" stimulates the release of stored glucose from the...

journal_title：Archives of physiology and biochemistry

authors： Dent JR,Chowdhury MK,Tchijov S,Dulson D,Smith G

更新日期：2016-01-01 00:00:00

abstract：:The present study was designed to examine the preventive effects of camel milk (CM) against the toxic effects of acute exposure to carbon tetrachloride (CCl4) on the heart tissue of mice. Administration of a single dose of CCl4 caused cardio toxicity as monitored by an increase in lipid peroxidation (thiobarbituric ac...

journal_title：Archives of physiology and biochemistry

authors： Hamed H,Gargouri M,Bellassoued K,Ghannoudi Z,Elfeki A,Gargouri A

更新日期：2018-07-01 00:00:00

abstract：:Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in...

journal_title：Archives of physiology and biochemistry

authors： Hosseini SA,Hamzavi K,Safarzadeh H,Salehi O

更新日期：2020-10-05 00:00:00

abstract：:Context: Exposure to Electomagnetic radiation fields of cell phones causes thyroid dysfunction and a previous study revealed that nesfatin-1 may affect functions of the thyroid gland.Objective: To study the role of nesfatin-1 on functions of rat's thyroid gland exposed to EMRF.Materials and methods: Thirty adult male ...

journal_title：Archives of physiology and biochemistry

authors： Hussien NI,Mousa AM,Shoman AA

更新日期：2020-06-17 00:00:00

abstract：BACKGROUND AND AIM:Tobago and Trinidad are two Caribbean islands with distinct genetic background and lifestyles; while Tobago is serene and a tourist centre, Trinidad is characterized by a hustling and bustling lifestyle. The study was aimed at determining and comparing the prevalence of the metabolic syndrome (MetS) ...

journal_title：Archives of physiology and biochemistry

authors： Ezenwaka CE,Nwagbara E,Seales D,Okali F,Hussaini S,Raja B,Wheeler V,Sell H,Avci H,Eckel J

更新日期：2007-10-01 00:00:00

abstract：AIM:A high-fat diet (HFD) can lead to obesity and related metabolic disorders. This study evaluated the preventive efficacy of myricetin derivative-rich fraction (MD) from Syzygium malaccense leaf extract against HFD-induced obesity, hyperglycaemia, and oxidative stress in C57BL/6J mice. METHODS:HFD-fed mice were admi...

journal_title：Archives of physiology and biochemistry

authors： Nallappan D,Ong KC,Palanisamy UD,Chua KH,Kuppusamy UR

更新日期：2020-08-19 00:00:00

abstract：:This study investigated the effects of garlic on anxiety- and depression-related behaviors and brain oxidative markers in streptozotocin (STZ)-induced diabetes in rats. Fifty-six male Wistar rats were randomly divided into seven experimental groups (n = 8/group): control, diabetic + saline, diabetic + garlic, diabetic...

journal_title：Archives of physiology and biochemistry

authors： Rahmani G,Farajdokht F,Mohaddes G,Babri S,Ebrahimi V,Ebrahimi H

更新日期：2020-05-01 00:00:00

abstract：:This study investigated the expression and underlying molecular mechanism of CPSF1 in diabetic retinopathy. Streptozotocin (STZ)-induced Sprague-Dawley (SD) rats were employed as a diabetic model, and high-glucose (HG)-induced human retinal vascular endothelial cells （HRVECs）were used as an in vitro experimental model...

journal_title：Archives of physiology and biochemistry

authors： Zhang J,Zhang X,Zou Y,Han F

更新日期：2020-02-12 00:00:00

abstract：:Diabetic cardiomyopathy consists of a series of structural and functional changes. Accumulating evidence supports the concept that a "cardiac stem cell compartment disease" plays an important role in the pathophysiology of diabetic cardiomyopathy. In diabetic hearts, human cardiac stem/progenitor cells (CSPC) are redu...

journal_title：Archives of physiology and biochemistry

authors： Leonardini A,Avogaro A

更新日期：2013-10-01 00:00:00

abstract：CONTEXT:Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. OBJECTIVE:To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. MATERIALS AND METHODS:Rats were divided into control, sham, sham + ghreli...

journal_title：Archives of physiology and biochemistry

authors： Eid RA,Alkhateeb MA,Al-Shraim M,Eleawa SM,Shatoor AS,El-Kott AF,Zaki MSA,Shatoor KA,Bin-Jaliah I,Al-Hashem FH

更新日期：2019-05-01 00:00:00

abstract：:This study investigates the effects of the islet hormones insulin (Ins), glucagon (Glu), and somatostatin (Som) with nerve stimulation (EFS) acetylcholine (ACh) and cholecytokinin-octapeptide (CCK-8) on amylase secretion and intracellular free calcium concentration [Ca(2+)](i) in the pancreas of age-matched control an...

journal_title：Archives of physiology and biochemistry

authors： Singh J,Yago MD,Adeghate E

更新日期：2001-07-01 00:00:00

abstract：:The authors conducted this meta-analysis to robustly estimate relationships between polymorphisms in VDR gene and the risk of osteoporosis by integrating the results of previous works. Medline, Embase, Wanfang, VIP and CNKI were searched thoroughly for eligible studies, and 73 genetic association studies were finally ...

journal_title：Archives of physiology and biochemistry

authors： Jiang LL,Zhang C,Zhang Y,Ma F,Guan Y

更新日期：2020-08-06 00:00:00