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Transcription gets to the checkpoint.

Abstract：

:The rapid cell proliferation characteristic of early animal embryos is accomplished with an abbreviated cell cycle and no DNA replication checkpoint. Blythe and Wieschaus provide evidence that nascent zygotic transcription precedes—and may trigger—this checkpoint at the midblastula transition.

journal_name

Cell

journal_title

Cell

authors

Laver JD,Lipshitz HD

doi

10.1016/j.cell.2015.02.051

subject

Has Abstract

pub_date

2015-03-12 00:00:00

pages

1043-4

issue

6

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(15)00252-4

journal_volume

160

pub_type

评论,杂志文章

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