How the sequence of a gene can tune its translation.

Abstract:

:Sixty-one codons specify 20 amino acids, offering cells many options for encoding a polypeptide sequence. Two new studies (Cannarrozzi et al., 2010; Tuller et al., 2010) now foster the idea that patterns of codon usage can control ribosome speed, fine-tuning translation to increase the efficiency of protein synthesis.

journal_name

Cell

journal_title

Cell

authors

Fredrick K,Ibba M

doi

10.1016/j.cell.2010.03.033

subject

Has Abstract

pub_date

2010-04-16 00:00:00

pages

227-9

issue

2

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(10)00321-1

journal_volume

141

pub_type

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