Abstract：
:Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized ultra-small lanthanide oxyfluoride nanocrystals (LaOF) for simultaneously targeted imaging cell cytoplasm and nucleus. As-prepared Arg-modified PAA capped LaOF: 45%Ce, 15%Tb nanocrystals (LaOF:Ce,Tb@PAA@Arg) possessed high water dispersibility, ultra-small size (∼5.7 nm) and double emissions (green and red) with high quantum yield (40%). Such functionalized nanocrystals presented high cellular biocompatibility and were successfully used to label living cells with very high contrast. These functionalized nanocrystals also exhibited significantly higher photostability and brightness as compared to commercial dyes. Such the ultra-small size, high photostability and intensity, double emissions, excellent biocompatibility and targeted ability, make as-prepared functionalized nanocrystals particularly promising for cellular and subcellular bioimaging applications.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Zhang J,Yan J,Yang Q,Yan Y,Li S,Wang L,Li C,Lei B,Yang G,He Wdoi
10.1177/0885328217725203subject
Has Abstractpub_date
2017-10-01 00:00:00pages
533-542issue
4eissn
0885-3282issn
1530-8022journal_volume
32pub_type
杂志文章abstract：:This study's aim consists of evaluating the adhesion and proliferation of mesenchymal stem cells (MSCs) derived from rat bone marrow on nanoparticle Titanium (Ti) surface. Hence, passage 3 MSCs were, respectively, seeded on nanoparticle Ti and pure Ti surfaces and then cultured for 32 h. Cell morphology and viability ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328211414750
更新日期：2013-01-01 00:00:00
abstract：:The aim of the paper is to obtain and characterize k-carrageenan-chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, and as a possible antitumoral agent in biological studies. We used the CaCO3 template to synthesize non-toxic CaCO3/BSA particles as microtemplates by coprecipitat...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215603797
更新日期：2016-01-01 00:00:00
abstract：:The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章,评审
doi：10.1177/088532829701200104
更新日期：1997-07-01 00:00:00
abstract：:An electronic sensor system for urinary bladder pressure monitoring requires an imbedding into a biocompatible, flexible, and liquid-impermeable material. Poly(dimethylsiloxane) (PDMS) was selected in the present set-up as packaging material because it fulfills the abovementioned requirements. However, the surface of ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328211422119
更新日期：2013-02-01 00:00:00
abstract：:The controlled release of insulin from a series of biodegradable hybrid hydrogel network containing dextran derivative of allyl isocyanate (dex-AI) and poly (D,L) lactide diacrylate macromer (PDLLAM) over a wide range of composition ratio was investigated. Laser confocal scanning microscope was used to understand the ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1106/088532802024248
更新日期：2002-04-01 00:00:00
abstract：:The incidence of fractures increases with age. This is partly due to extraosseous factors and partly to the increased fragility of the bone material itself. Ageing adversely affects the "quality" of human bone material, its elastic and ultimate properties. The hypothesis here is that these effects are caused by factor...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1106/5JUJ-TFJ3-JVVA-3RJ0
更新日期：2001-01-01 00:00:00
abstract：:Reconstruction of critical sized bone injuries is a major problem that continues to inspire the design of new materials and grafts. Natural ceramics (hydroxyapatite (HA) coralline HA, or synthetic HA) and β-tricalcium phosphate (β-TCP) are being explored for use as scaffolds in bone tissue engineering, among several o...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328211415132
更新日期：2013-01-01 00:00:00
abstract：:Novel in situ polymerizable liquid three-arm biodegradable oligomeric polyesters based upon glycolic acid (GA), L-lactic acid (LLA), and their copolymers are synthesized and characterized. Injectable and in situ curable polymer neat resins and their composites formulated with bioabsorbable beta-tricalcium phosphate ar...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328206068691
更新日期：2007-07-01 00:00:00
abstract：:While BMP-7 (OP-1) is one of the most potent growth factors in cartilage tissue engineering, the effects of exogenous low concentration BMP-7 on osteoarthritic chondrocytes are still unknown. Human osteoarthritic chondrocytes obtained from the femoral condyles of 10 patients were grown either in monolayer or in 3D col...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328210388439
更新日期：2012-03-01 00:00:00
abstract：:Understanding the structure-function relationship in biomaterial constructs is critical in optimizing biological outcomes. For ensheathed structures such as peripheral nerve, engineering implantable tissue substitutes has been challenging. This is due to a unique geometry of thin-walled microtube arrays composed mostl...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218804338
更新日期：2018-10-01 00:00:00
abstract：:Aluminum-free glass ionomer cements (GICs) are under development for orthopedic applications, but are limited by their insufficient handling properties. Here, the addition of calcium polyphosphate (CPP) was investigated as an additive to an experimental zinc-silicate glass ionomer cement. A 50% maximum increase in wor...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215568985
更新日期：2015-07-01 00:00:00
abstract：:In this work, we report brushite-based calcium phosphate cement (CPC) system to enhance the in vivo biodegradation and tissue in-growth by incorporation of micro-channeled hydroxyapatite (HAp) granule and silicon and sodium addition in calcium phosphate precursor powder. Sodium- and silicon-rich calcium phosphate powd...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215601938
更新日期：2016-01-01 00:00:00
abstract：:We assess the effects of chemical processing, ethylene oxide sterilization, and threading on bone surface and mechanical properties of bovine undecalcified bone screws. In addition, we evaluate the possibility of manufacturing bone screws with predefined dimensions. Scanning electronic microscopic images show that che...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208092110
更新日期：2009-03-01 00:00:00
abstract：:The purpose of this study is the development of a nerve electrode that reorganizes nerve geometry slowly and controllably. The Flat Interface Nerve Electrode (FINE) can reshape the nerve into an elongated oval and provide selective stimulation. However, the rate of closure of this electrode is difficult to control. Th...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208097426
更新日期：2009-09-01 00:00:00
abstract：:Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328209359959
更新日期：2011-03-01 00:00:00
abstract：:The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829200700203
更新日期：1992-10-01 00:00:00
abstract：:Gold nanomaterials possess unique physical and chemical properties, which attracted much attention in recent years. As a new type of gold nanomaterials, gold nanostars (GNSTs) have been prepared and characterized in this study. GNSTs under near-infrared (NIR) light irradiation can exert not only cancer photothermal th...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215594481
更新日期：2015-11-01 00:00:00
abstract：:An experimental and computational investigation of the self-tapping ability of carbon fibre reinforced polyetheretherketone (CFR-PEEK) has been conducted. Six CFR-PEEK suture anchor designs were investigated using PEEK-OPTIMA® Reinforced, a medical grade of CFR-PEEK. Experimental tests were conducted to investigate th...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328214535274
更新日期：2014-10-01 00:00:00
abstract：:In this study, the effects of sodium carbonate (Na(2)CO(3) ) solution with different concentrations (10, 15, 20, and 25 wt%) as liquid phase on the setting time and compressive strength of tricalcium silicate bone cements are investigated. The in vitro bioactivity and degradability of the resultant Ca(3)SiO(5)-Na(2)CO...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208088714
更新日期：2008-11-01 00:00:00
abstract：:The setup of colloidal hybrid nanosystems based on biomimetic calcium phosphate apatites doped with europium ions has recently raised great interest in the pharmacological community, especially due to their bio-inspired character. This is especially relevant in relation with medical imaging for cancer diagnosis. Quest...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212473510
更新日期：2014-01-01 00:00:00
abstract：:The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212437610
更新日期：2013-07-01 00:00:00
abstract：:Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328220915816
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829501000207
更新日期：1995-10-01 00:00:00
abstract：:Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on wate...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215598940
更新日期：2015-11-01 00:00:00
abstract：:The aim of this study was to design a new natural/synthetic bioactive bone scaffold for potential use in bone replacement applications. We developed a tri-component osteogenic composite scaffold made of collagen (Coll), hydroxyapatite (HA) and poly(l-lactide-co-ε-caprolactone) (PLCL). This Coll/HA/PLCL composite scaff...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328213486705
更新日期：2014-02-01 00:00:00
abstract：:Polypropylene meshes are standard for hernia repair. Matrix metalloproteinases play a central role in inflammation. To reduce the inflammatory response and improve remodelling with an associated reduction of hernia recurrence, we modified polypropylene meshes by nanofibre coating and saturation with the broad-spectrum...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218759043
更新日期：2018-05-01 00:00:00
abstract：:Poly(2-hydroxyethyl methacrylate) hydrogel intraocular lenses, containing adrenochrome-melanin, were manufactured and implanted in animal eyes in order to assess the effect of melanin upon (a) biocompatibility of implants with the eye tissues, and (b) fibrous proliferation of lens epithelium responsible for the opacif...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829500900305
更新日期：1995-01-01 00:00:00
abstract：:The effect of hybrid material-graphene flakes with Fe3O4 nanospheres (GO-Fe3O4), graphene oxide (GO) and magnetite nanospheres (Fe3O4) in rotating magnetic field on mammalian cells metabolism has been studied. Several reports shown that exposure to magnetic field may have influence on cellular membrane permeability. T...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216628762
更新日期：2016-04-01 00:00:00
abstract：:Thrombosis is the most serious acute problem for small diameter arterial bypass grafts. In this research, small diameter expanded polytetrafluoroethylene (e-PTFE) vascular grafts were coated with acetylsalicylic acid (ASA) loaded poly (d,l-lactide) (PLA) by a solvent casting method. The feasibility and efficacy of thi...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829400800404
更新日期：1994-04-01 00:00:00
abstract：:The in vitro effect of platelet-rich plasma (PRP) on cell loading, proliferation, and osteogenic differentiation of human mesenchymal stem cells (MSC) is assessed on distinct resorbable and synthetic calcium phosphate scaffolds. A high specific surface area scaffold composed of calcium-deficient hydroxyapatite (CDHA; ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328207088269
更新日期：2008-09-01 00:00:00
