Brushite-based calcium phosphate cement with multichannel hydroxyapatite granule loading for improved bone regeneration.

abstract：:Bone tissue engineering, which relies on the interactions between stem cells and suitable scaffold materials, represents a highly desirable alternative to currently used allograft or autograft strategies for the treatment of bone defects caused by injury or disease, with one of the major challenges being to generate s...

journal_title：Journal of biomaterials applications

authors： Feng J,Chong M,Chan J,Zhang Z,Teoh SH,Thian ES

更新日期：2014-07-01 00:00:00

abstract：:Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...

journal_title：Journal of biomaterials applications

authors： Chang H,Xiang H,Yao Z,Yang S,Tu M,Zhang X,Yu B

更新日期：2020-07-01 00:00:00

abstract：:A series biodegradable poly (γ-glutamic acid)/beta-tricalcium phosphate (γ-PGA/TCP) nanocomposites were prepared which were composed of poly-γ-glutamic acid polymerized in situ with β-tricalcium phosphate and physiochemically characterized as bone graft substitutes. The particle size via dynamic light scattering, the ...

journal_title：Journal of biomaterials applications

authors： Shu XL,Shi QS,Feng J,Yang YH,Zhou G,Li WR

更新日期：2016-07-01 00:00:00

abstract：:Cellulose acetate phthalate and Pluronic F-127 combined together (70:30 wt:wt) create a rigid, surface-eroding association polymer. To impart flexibility into the polymer system and allow for a drug delivery film that can contour to varying wound shapes, plasticizers were added. Triethyl citrate or tributyl citrate wa...

journal_title：Journal of biomaterials applications

authors： Rabek CL,Van Stelle R,Dziubla TD,Puleo DA

更新日期：2014-01-01 00:00:00

abstract：:Type 1 diabetes mellitus is a serious disease comprising approximately 10% of all diabetes cases, and the global incidence of type 1 diabetes mellitus is steadily rising without any promise of a cure in the near future. Although islet transplantation has proven to be an effective means of treating type 1 diabetes mell...

journal_title：Journal of biomaterials applications

authors： Xu L,Guo Y,Huang Y,Xu Y,Lu Y,Wang Z

更新日期：2019-04-01 00:00:00

abstract：:Eight different chemicals were investigated as potential candidate coupling agents for phosphate glass fibre reinforced polylactic acid composites. Evidence of reaction of the coupling agents with phosphate glass and their effect on surface wettability and glass degradation were studied along with their principle role...

journal_title：Journal of biomaterials applications

authors： Hasan MS,Ahmed I,Parsons AJ,Rudd CD,Walker GS,Scotchford CA

更新日期：2013-09-01 00:00:00

abstract：:The incidence of fractures increases with age. This is partly due to extraosseous factors and partly to the increased fragility of the bone material itself. Ageing adversely affects the "quality" of human bone material, its elastic and ultimate properties. The hypothesis here is that these effects are caused by factor...

journal_title：Journal of biomaterials applications

authors： Zioupos P

更新日期：2001-01-01 00:00:00

abstract：:Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized...

journal_title：Journal of biomaterials applications

authors： Zhang J,Yan J,Yang Q,Yan Y,Li S,Wang L,Li C,Lei B,Yang G,He W

更新日期：2017-10-01 00:00:00

abstract：:Nowadays, exceptional advantages of silk fibroin over synthetic and natural polymers have impelled the scientists to application of this biomaterial for tissue engineering purposes. Recently, we showed that embedding natural degummed silk fibers in regenerated Bombyx mori silk-based scaffold significantly increases th...

journal_title：Journal of biomaterials applications

authors： Mobini S,Taghizadeh-Jahed M,Khanmohammadi M,Moshiri A,Naderi MM,Heidari-Vala H,Ashrafi Helan J,Khanjani S,Springer A,Akhondi MM,Kazemnejad S

更新日期：2016-01-01 00:00:00

abstract：:Hemocompatibility is the goal for any biomaterial contained in extracorporeal life supporting medical devices. The hallmarks for hemocompatibility include nonthrombogenicity, platelet preservation, and maintained platelet function. Both in vitro and in vivo assays testing for compatibility of the blood/biomaterial int...

journal_title：Journal of biomaterials applications

authors： Major TC,Handa H,Annich GM,Bartlett RH

更新日期：2014-10-01 00:00:00

abstract：:In this study, the effects of sodium carbonate (Na(2)CO(3) ) solution with different concentrations (10, 15, 20, and 25 wt%) as liquid phase on the setting time and compressive strength of tricalcium silicate bone cements are investigated. The in vitro bioactivity and degradability of the resultant Ca(3)SiO(5)-Na(2)CO...

journal_title：Journal of biomaterials applications

authors： Zhiguang Huan,Jiang Chang

更新日期：2008-11-01 00:00:00

abstract：:Excessive demineralization in osteoporotic bones impairs its self-regeneration potential following a defect/fracture and is of great concern among the aged population. In this context, implants with inherent osteogenic ability loaded with therapeutic ions like Strontium (Sr2+) may bring forth promising outcomes. Micro...

journal_title：Journal of biomaterials applications

authors： Chandran S,Babu S S,Vs HK,Varma HK,John A

更新日期：2016-10-01 00:00:00

abstract：:Dicalcium phosphate dihydrate particles functionalized with triethyleneglycol dimethacrylate were synthesized and added to a photocurable mixture of bisphenol-A glycidyl dimethacrylate and triethyleneglycol dimethacrylate with the purpose of developing a resin composite capable of releasing calcium and phosphate ions ...

journal_title：Journal of biomaterials applications

authors： Rodrigues MC,Xavier TA,Arana-Chavez VE,Braga RR

更新日期：2017-01-01 00:00:00

abstract：:Pluronic® F127 is a biocompatible, injectable, and thermoresponsive polymer with promising biomedical applications. In this study, a chemically modified form, i.e., Pluronic ALA-L with tailored degradation rate, was tested as an encapsulation vehicle for osteoblastic cells. UV cross-linking of the modified polymer res...

journal_title：Journal of biomaterials applications

authors： Lippens E,Swennen I,Gironès J,Declercq H,Vertenten G,Vlaminck L,Gasthuys F,Schacht E,Cornelissen R

更新日期：2013-03-01 00:00:00

abstract：:The setup of colloidal hybrid nanosystems based on biomimetic calcium phosphate apatites doped with europium ions has recently raised great interest in the pharmacological community, especially due to their bio-inspired character. This is especially relevant in relation with medical imaging for cancer diagnosis. Quest...

journal_title：Journal of biomaterials applications

authors： Al-Kattan A,Santran V,Dufour P,Dexpert-Ghys J,Drouet C

更新日期：2014-01-01 00:00:00

abstract：:Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...

journal_title：Journal of biomaterials applications

authors： Lantos PR

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...

journal_title：Journal of biomaterials applications

authors： Edwards A,Carson RJ,Bowald S,Quist WC

更新日期：1995-10-01 00:00:00

abstract：:Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA) scaffolds were fabricated via freeze-drying wi...

journal_title：Journal of biomaterials applications

authors： Koç A,Finkenzeller G,Elçin AE,Stark GB,Elçin YM

更新日期：2014-11-01 00:00:00

abstract：:Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...

journal_title：Journal of biomaterials applications

authors： Dhawan S,Kapil R,Kapoor DN

更新日期：2011-03-01 00:00:00

abstract：:Carbon-fibre-reinforced polyether ether ketone (CFR-PEEK) exhibits excellent biomechanical properties as it has an elastic modulus similar to bone. However, CFR-PEEK displays inferior biocompatibility compared with titanium alloy and coating techniques are therefore of interest in order to improve integration. In this...

journal_title：Journal of biomaterials applications

authors： Suska F,Omar O,Emanuelsson L,Taylor M,Gruner P,Kinbrum A,Hunt D,Hunt T,Taylor A,Palmquist A

更新日期：2014-08-01 00:00:00

abstract：:Polypropylene meshes are standard for hernia repair. Matrix metalloproteinases play a central role in inflammation. To reduce the inflammatory response and improve remodelling with an associated reduction of hernia recurrence, we modified polypropylene meshes by nanofibre coating and saturation with the broad-spectrum...

journal_title：Journal of biomaterials applications

authors： Böhm G,Groll J,Heffels KH,Heussen N,Ink P,Alizai HP,Neumann UP,Schnabel R,Mirastschijski U

更新日期：2018-05-01 00:00:00

abstract：:Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...

journal_title：Journal of biomaterials applications

authors： Gosau M,Bürgers R,Vollkommer T,Holzmann T,Prantl L

更新日期：2013-08-01 00:00:00

abstract：:At present all the commercially available "medical grade" urethane elastomers exhibit a phenomenon known as environmental stress cracking (ESC). This phenomenon is characterized by surface microcracking when the elastomer is elongated while in vivo. The degree of strain that is required to initiate microcracking varie...

journal_title：Journal of biomaterials applications

authors： Szycher M,Reed AM,Siciliano AA

更新日期：1991-10-01 00:00:00

abstract：:Antenna coupling microwave plasma enables a highly oxidative treatment of the outmost surface of polypropylene (PP) nonwoven fabric within a short time period. Subsequently, grafting copolymerization with acrylic acid (AAc) makes the plasma-treated fabric durably hydrophilic and excellent in water absorbency. With hig...

journal_title：Journal of biomaterials applications

authors： Tyan YC,Liao JD,Wu YT,Klauser R

更新日期：2002-10-01 00:00:00

abstract：:Thrombosis is the most serious acute problem for small diameter arterial bypass grafts. In this research, small diameter expanded polytetrafluoroethylene (e-PTFE) vascular grafts were coated with acetylsalicylic acid (ASA) loaded poly (d,l-lactide) (PLA) by a solvent casting method. The feasibility and efficacy of thi...

journal_title：Journal of biomaterials applications

authors： Hall JD,Rittgers SE,Schmidt SP

更新日期：1994-04-01 00:00:00

abstract：:Calcium polyphosphate is a biodegradable bone substitute. It remains a challenge to prepare porous calcium polyphosphate with desired gradient porous structures. In this study, a modified one-step gravity sintering method was used to prepare calcium polyphosphate scaffolds with desired-gradient-pore-size distribution....

journal_title：Journal of biomaterials applications

authors： Chen L,Song W,Markel DC,Shi T,Muzik O,Matthew H,Ren W

更新日期：2016-02-01 00:00:00

abstract：:In this study, a novel bilayer scaffold composed of electrospun polycaprolactone and poly(lacto-co-glycolic acid) (PCL/PLGA) membrane and glutaraldehyde (3.5% v/v) cross-linked chitosan/gelatin hydrogel was fabricated using two methods: electrospinning of the membrane onto the lyophilized hydrogel (BS-1) and membrane ...

journal_title：Journal of biomaterials applications

authors： Franco RA,Min YK,Yang HM,Lee BT

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study is the development of a nerve electrode that reorganizes nerve geometry slowly and controllably. The Flat Interface Nerve Electrode (FINE) can reshape the nerve into an elongated oval and provide selective stimulation. However, the rate of closure of this electrode is difficult to control. Th...

journal_title：Journal of biomaterials applications

authors： Caparso AV,Durand DM,Mansour JM

更新日期：2009-09-01 00:00:00

abstract：:The paper studies the coupling reaction by covalent bonding of acetylamino-2-sulfamoyl-1,3,4-thiodiazole (AcAA) on the poly(acrylic acid-costyrene) copolymer (PAcA-S) in homogeneous system, in the presence of dicyclohexylcarbodiimide (DCC) as activator. The influence of some factors on coupling efficiency (the drug/su...

journal_title：Journal of biomaterials applications

authors： Dumitriu S,Popa M,Dărângă M,Dumitriu C

更新日期：1992-07-01 00:00:00

abstract：:In this paper, the authors describe a novel type of hydrogel coating prepared from the copolymer of human serum albumin and oxidized dextran. The material was designed as a hydrogel sealant for polyester (Dacron®)-based vascular grafts. Dextran was chosen as a coating material due to its anti-thrombogenic properties. ...

journal_title：Journal of biomaterials applications

authors： Lisman A,Butruk B,Wasiak I,Ciach T

更新日期：2014-05-01 00:00:00