Abstract:
:Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper concentrations (Cu1, Cu2) were artificially aged. Surface roughness and surface free energy were assessed. The specimens were incubated in an S. epidermidis suspension. We assessed the quantification and the viability of adhering bacteria by live/dead cell labeling with fluorescence microscopy. Additionally, inhibition of bacterial growth was evaluated by agar diffusion, broth culture, and quantitative culture of surface bacteria. No significant differences in surface roughness and surface free energy were found between Cu0, Cu1 and Cu2. Aging did not change surface characteristics and the extent of bacterial adhesion. Fluorescence microscopy showed that the quantity of bacteria on Cu0 was significantly higher than that on Cu1 and Cu2. The ratio of dead to total adhering bacteria was significantly lower on Cu0 than on Cu1 and Cu2, and tended to be higher for Cu2 than for Cu1. Quantitative culture showed equal trends. Copper additives seem to have anti-adherence and bactericidal effects on S. epidermidis in vitro.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Gosau M,Bürgers R,Vollkommer T,Holzmann T,Prantl Ldoi
10.1177/0885328212441957subject
Has Abstractpub_date
2013-08-01 00:00:00pages
187-98issue
2eissn
0885-3282issn
1530-8022pii
0885328212441957journal_volume
28pub_type
杂志文章abstract::Injectable thermo-sensitive hydrogels have a potential application in bone tissue engineering for their sensitivities and minimal invasive properties. Human dental pulp stem cells have been considered a promising tool for tissue reconstruction. The objective of this study was to investigate the proliferation and osteo...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328216661566
更新日期:2016-09-01 00:00:00
abstract::To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic fu...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215618354
更新日期:2016-02-01 00:00:00
abstract::A multifunctional targeted nanoplatform combining photothermal therapy and chemotherapy has emerged as a promising strategy for comprehensive therapies of breast cancer. In this study, we constructed human epidermal growth factor receptor 2 (Her2)-targeted gold nanoshelled poly(lactic-co-glycolic acid) hybrid nanocaps...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220929616
更新日期:2020-09-01 00:00:00
abstract::This study's aim consists of evaluating the adhesion and proliferation of mesenchymal stem cells (MSCs) derived from rat bone marrow on nanoparticle Titanium (Ti) surface. Hence, passage 3 MSCs were, respectively, seeded on nanoparticle Ti and pure Ti surfaces and then cultured for 32 h. Cell morphology and viability ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328211414750
更新日期:2013-01-01 00:00:00
abstract::Melt electrowriting (MEW) can print high-resolution scaffolds with the ultrafine fibers from 800 nm to 20 µm. However, the cell seeding efficiency relatively low due to the large pore size of the MEW scaffold. Here, we reported a method to solve this dilemma by electrospinning a gelatin methacrylate (GelMA) hydrogel f...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220962606
更新日期:2021-01-01 00:00:00
abstract::Even though Ti-based implants are the most used materials for hard tissue replacement, they may present lack of osseointegration on the long term, due to their inertness. Hydrothermal treatment (HT) is a useful technique for the synthesis of firmly attached, highly crystalline coatings made of anatase titanium dioxide...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215569091
更新日期:2015-07-01 00:00:00
abstract::Appropriate design of dialysis membranes requires correct values of structural parameters such as pore radius, surface porosity, water content and tortuosity. It is impossible, however, to find the pore radius of dialysis membranes using a mercury porosimeter or an electron microscope because the pores are only severa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532828900400201
更新日期:1989-10-01 00:00:00
abstract::A series of cellulose/soy protein isolate (SPI) sponges was prepared using a freeze-drying process. The effect of the SPI content on the structure of the sponges was characterized by Fourier transform infrared spectrometry (FT-IR), X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM). It showed that...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328208099337
更新日期:2010-02-01 00:00:00
abstract::The process of molecular self-assembly plays a crucial role in formulation of polymeric nanoparticulated drug delivery carriers as it creates the possibility for enhanced drug encapsulation and carrier surface engineering. This study aimed to develop a novel self-assembled polymeric micelles for targeted delivery in t...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214549612
更新日期:2015-01-01 00:00:00
abstract::Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on wate...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215598940
更新日期:2015-11-01 00:00:00
abstract::Calcium polyphosphate is a biodegradable bone substitute. It remains a challenge to prepare porous calcium polyphosphate with desired gradient porous structures. In this study, a modified one-step gravity sintering method was used to prepare calcium polyphosphate scaffolds with desired-gradient-pore-size distribution....
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215608335
更新日期:2016-02-01 00:00:00
abstract::Silicate-based cements have been developed as a class of bioactive and biodegradable bone cements owing to their good in vitro bioactivity and ability to dissolve in a simulated body fluid. Until recently, however, the in vivo evidence of their ability to support bone regeneration is still scarce. In the present study...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328217715428
更新日期:2017-08-01 00:00:00
abstract::At present all the commercially available "medical grade" urethane elastomers exhibit a phenomenon known as environmental stress cracking (ESC). This phenomenon is characterized by surface microcracking when the elastomer is elongated while in vivo. The degree of strain that is required to initiate microcracking varie...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829100600202
更新日期:1991-10-01 00:00:00
abstract::Composite hydrogel systems consisting of oxidized alginate, gelatin, and biphasic calcium phosphate were fabricated by the Schiff-base reaction and the effect of oxidation of alginate on the microstructure, material properties, and biocompatibility were evaluated. Alginate was modified by oxidizing the attached -OH gr...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328211404265
更新日期:2012-09-01 00:00:00
abstract::Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328217725203
更新日期:2017-10-01 00:00:00
abstract::Polyelectrolyte capsules are seen as promising nanotechnology based drug delivery systems. In previous works, we have demonstrated the possibility to fabricate bio-activated surface layer containing capsules with improved features in terms of biocompatibility. In this study, we have characterized the permeability prop...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212446358
更新日期:2013-08-01 00:00:00
abstract::A biosensor for the analysis of D-amino acids is described. Carbon paste (graphite/paraffin oil) was chemically modified with immobilized D-amino acid oxidase and either horse-radish peroxidase or fungal peroxidase from Arthromyces ramosus. The two enzymes dissolved in buffer, together with an amine containing oligome...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829300800204
更新日期:1993-10-01 00:00:00
abstract::Nanohydroxyapatite (nanoHA), due to its chemical properties, has appeared as an exceptionally promising bioceramic to be used as bone regeneration material. Staphylococcus epidermidis have emerged as major nosocomial pathogens associated with infections of implanted medical devices. In this work, the purpose was to st...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213507300
更新日期:2014-05-01 00:00:00
abstract::The purpose of this investigation is to study the effect of long-term subcutaneous aluminum polymeric implants on aluminum release and accumulation in various tissues in rats. The implants were formulated using silicone rubber and polyurethane polymers and three different aluminum salts. The polymeric matrices were ev...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829601100103
更新日期:1996-07-01 00:00:00
abstract::This investigation describes the synthesis and in vitro evaluation of cationic hydrogel sub-microparticles based on polydimethylaminoethylmethacrylate for oral insulin delivery. Polymerization of dimethylaminoethylmethacrylate was carried out in aqueous medium with potassium persulfate as the initiator. Quaternization...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212437392
更新日期:2013-07-01 00:00:00
abstract:PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829501000207
更新日期:1995-10-01 00:00:00
abstract::The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829200700203
更新日期:1992-10-01 00:00:00
abstract::Thrombosis is the most serious acute problem for small diameter arterial bypass grafts. In this research, small diameter expanded polytetrafluoroethylene (e-PTFE) vascular grafts were coated with acetylsalicylic acid (ASA) loaded poly (d,l-lactide) (PLA) by a solvent casting method. The feasibility and efficacy of thi...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829400800404
更新日期:1994-04-01 00:00:00
abstract::Polymer biocomposites based on segmented poly(ester urethane) and extracellular matrix components have been prepared for the development of tissue engineering applications with improved biological characteristics of the materials in contact with blood and tissues for long periods. Thermal, dynamical, and dielectrical ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328210394468
更新日期:2012-08-01 00:00:00
abstract::Three types of commercially available ultra-high molecular weight polyethylene (UHMWPE) acetabular cups currently used in total hip arthroplasty have been studied by means of Raman micro-spectroscopy to unfold the microstructural modification induced by the oxidative degradation after accelerated aging with and withou...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214548693
更新日期:2015-01-01 00:00:00
abstract::The effect of hybrid material-graphene flakes with Fe3O4 nanospheres (GO-Fe3O4), graphene oxide (GO) and magnetite nanospheres (Fe3O4) in rotating magnetic field on mammalian cells metabolism has been studied. Several reports shown that exposure to magnetic field may have influence on cellular membrane permeability. T...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328216628762
更新日期:2016-04-01 00:00:00
abstract::Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328207079731
更新日期:2008-05-01 00:00:00
abstract::In order to induce esophageal muscle cells' orientation, the silicon wafer with prototype 1 and prototype 2 was designed. Prototype 1 has micro-channels of 200 µm width and 30 µm depth with 30 µm wide wall as the interval. Prototype 2 has channels of 100 µm width and 30 µm depth with a discontinuous wall which has 30 ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215627585
更新日期:2016-04-01 00:00:00
abstract::Aluminum-free glass ionomer cements (GICs) are under development for orthopedic applications, but are limited by their insufficient handling properties. Here, the addition of calcium polyphosphate (CPP) was investigated as an additive to an experimental zinc-silicate glass ionomer cement. A 50% maximum increase in wor...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215568985
更新日期:2015-07-01 00:00:00
abstract::While BMP-7 (OP-1) is one of the most potent growth factors in cartilage tissue engineering, the effects of exogenous low concentration BMP-7 on osteoarthritic chondrocytes are still unknown. Human osteoarthritic chondrocytes obtained from the femoral condyles of 10 patients were grown either in monolayer or in 3D col...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328210388439
更新日期:2012-03-01 00:00:00