Development of a microporous compliant small bore vascular graft.

Abstract:

PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression which accommodates changes in volume. METHOD:We have utilized efficient low temperature coagulation technology to develop a unique range of small diameter microporous vascular grafts using ChronoFlex, a biodurable polycarbonate urethane. RESULTS:Grafts have been subjected to a range of in vitro and in vivo testing, demonstrating excellent physical and mechanical characteristics, self-sealing, maintenance of compliance and pulsatile flow in situ and patency up to twenty-two weeks.

journal_name

J Biomater Appl

authors

Edwards A,Carson RJ,Bowald S,Quist WC

doi

10.1177/088532829501000207

subject

Has Abstract

pub_date

1995-10-01 00:00:00

pages

171-87

issue

2

eissn

0885-3282

issn

1530-8022

journal_volume

10

pub_type

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