Abstract:
PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression which accommodates changes in volume. METHOD:We have utilized efficient low temperature coagulation technology to develop a unique range of small diameter microporous vascular grafts using ChronoFlex, a biodurable polycarbonate urethane. RESULTS:Grafts have been subjected to a range of in vitro and in vivo testing, demonstrating excellent physical and mechanical characteristics, self-sealing, maintenance of compliance and pulsatile flow in situ and patency up to twenty-two weeks.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Edwards A,Carson RJ,Bowald S,Quist WCdoi
10.1177/088532829501000207subject
Has Abstractpub_date
1995-10-01 00:00:00pages
171-87issue
2eissn
0885-3282issn
1530-8022journal_volume
10pub_type
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