Evaluation of nano-biphasic calcium phosphate ceramics for bone tissue engineering applications: in vitro and preliminary in vivo studies.

abstract：:Tendon tears are a relevant concern for today's national health systems because of their social impact and high recurrence rate. The current gold standard for fixing tendon tears is surgical repair; however, this strategy is not able to fully re-establish tendon integrity and functionality. Tissue engineering approach...

journal_title：Journal of biomaterials applications

authors： Fotticchia A,Musson D,Lenardi C,Demirci E,Liu Y

更新日期：2018-07-01 00:00:00

abstract：:NiTi alloy is used as a biomaterial due to its pseudoelastic behaviour. It exhibits a great potential in dental and orthopedic applications where constant correcting loads are required. In order to use such materials, it is necessary to investigate the effect of the cyclic straining upon the transformation stresses an...

journal_title：Journal of biomaterials applications

authors： Gil FJ,Planell JA

更新日期：1998-01-01 00:00:00

abstract：:Using a hydraulic stress simulator, the mechanical behavior of the porcine pericardium used in the construction of cardiac valve leaflets was characterized following the same procedure employed with calf pericardium in Part 1 of this study. One hundred fifty pairs of tissue samples were subjected to tensile testing to...

journal_title：Journal of biomaterials applications

authors： García Páez JM,Carrera A,Herrero EJ,Millán I,Rocha A,Cordón A,Sainz N,Mendez J,Castillo-Olivares JL

更新日期：2001-07-01 00:00:00

abstract：:The aim of this study was to evaluate the possibility of metal complex formation between sodium-phosphorylated chitosan (PCTS) and ZnO. The polymer-metal complex formation was investigated in terms of thermal degradation. The structure deduction of the PCTS/ZnO complex was investigated by means of Fourier transform in...

journal_title：Journal of biomaterials applications

authors： Srakaew V,Ruangsri P,Suthin K,Thunyakitpisal P,Tachaboonyakiat W

更新日期：2012-11-01 00:00:00

abstract：:Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized...

journal_title：Journal of biomaterials applications

authors： Zhang J,Yan J,Yang Q,Yan Y,Li S,Wang L,Li C,Lei B,Yang G,He W

更新日期：2017-10-01 00:00:00

abstract：:At present all the commercially available "medical grade" urethane elastomers exhibit a phenomenon known as environmental stress cracking (ESC). This phenomenon is characterized by surface microcracking when the elastomer is elongated while in vivo. The degree of strain that is required to initiate microcracking varie...

journal_title：Journal of biomaterials applications

authors： Szycher M,Reed AM,Siciliano AA

更新日期：1991-10-01 00:00:00

abstract：:The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...

journal_title：Journal of biomaterials applications

authors： Carballo J,Ferreirós CM,Criado MT

更新日期：1992-10-01 00:00:00

abstract：:The production of large quantities of functional vascularized bone tissue ex vivo still represent an unmet clinical challenge. Microcarriers offer a potential solution to scalable manufacture of bone tissue due to their high surface area-to-volume ratio and the capacity to be assembled using a modular approach. Microc...

journal_title：Journal of biomaterials applications

authors： Peticone C,De Silva Thompson D,Owens GJ,Kim HW,Micheletti M,Knowles JC,Wall I

更新日期：2017-09-01 00:00:00

abstract：:Herb borneol is usually used in clinics for the treatment of central nervous system illness, for its ability of blood-brain barrier permeability, although its poor water solubility and poor bioavailability limit its clinical application to some degree. In this study, we developed a novel nanoparticle combining the ben...

journal_title：Journal of biomaterials applications

authors： Liu Y,Rao L,Zhang H,Cen Y,Cheng K

更新日期：2018-10-01 00:00:00

abstract：:Melt electrowriting (MEW) can print high-resolution scaffolds with the ultrafine fibers from 800 nm to 20 µm. However, the cell seeding efficiency relatively low due to the large pore size of the MEW scaffold. Here, we reported a method to solve this dilemma by electrospinning a gelatin methacrylate (GelMA) hydrogel f...

journal_title：Journal of biomaterials applications

authors： Ye W,Xie C,Liu Y,He Y,Gao Q,Ouyang A

更新日期：2021-01-01 00:00:00

abstract：:In order to induce esophageal muscle cells' orientation, the silicon wafer with prototype 1 and prototype 2 was designed. Prototype 1 has micro-channels of 200 µm width and 30 µm depth with 30 µm wide wall as the interval. Prototype 2 has channels of 100 µm width and 30 µm depth with a discontinuous wall which has 30 ...

journal_title：Journal of biomaterials applications

authors： Hou L,Gong C,Zhu Y

更新日期：2016-04-01 00:00:00

abstract：:Glass Polyalkenoate Cements (GPCs) based on strontium calcium zinc silicate (Sr-Ca-Zn-SiO2) glasses and high molecular weight poly(acrylic acid) (PAA) have been shown to exhibit suitable mechanical properties for orthopaedic arthroplasty applications, however for vertebroplasty and other medical luting applications th...

journal_title：Journal of biomaterials applications

authors： Clarkin O,Boyd D,Towler MR

更新日期：2010-02-01 00:00:00

abstract：:Nanohydroxyapatite (nanoHA), due to its chemical properties, has appeared as an exceptionally promising bioceramic to be used as bone regeneration material. Staphylococcus epidermidis have emerged as major nosocomial pathogens associated with infections of implanted medical devices. In this work, the purpose was to st...

journal_title：Journal of biomaterials applications

authors： Barros J,Grenho L,Manuel CM,Ferreira C,Melo L,Nunes OC,Monteiro FJ,Ferraz MP

更新日期：2014-05-01 00:00:00

abstract：:Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...

journal_title：Journal of biomaterials applications

authors： Dhawan S,Kapil R,Kapoor DN

更新日期：2011-03-01 00:00:00

abstract：:The different barriers that slow the penetration of active ingredients administered by the ocular route are described, and some novel dosage forms designed for this route are discussed. Both precorneal and corneal factors considerably restrict ocular penetration. The low bioavailability of classical ophthalmic dosage ...

journal_title：Journal of biomaterials applications

authors： Aiache JM,el Meski S,Beyssac E,Serpin G

更新日期：1997-01-01 00:00:00

abstract：:The effect of hybrid material-graphene flakes with Fe3O4 nanospheres (GO-Fe3O4), graphene oxide (GO) and magnetite nanospheres (Fe3O4) in rotating magnetic field on mammalian cells metabolism has been studied. Several reports shown that exposure to magnetic field may have influence on cellular membrane permeability. T...

journal_title：Journal of biomaterials applications

authors： Urbas K,Jedrzejczak-Silicka M,Rakoczy R,Zaborski D,Mijowska E

更新日期：2016-04-01 00:00:00

abstract：:Silicate-based cements have been developed as a class of bioactive and biodegradable bone cements owing to their good in vitro bioactivity and ability to dissolve in a simulated body fluid. Until recently, however, the in vivo evidence of their ability to support bone regeneration is still scarce. In the present study...

journal_title：Journal of biomaterials applications

authors： Ma B,Huan Z,Xu C,Ma N,Zhu H,Zhong J,Chang J

更新日期：2017-08-01 00:00:00

abstract：:Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...

journal_title：Journal of biomaterials applications

authors： Chang H,Xiang H,Yao Z,Yang S,Tu M,Zhang X,Yu B

更新日期：2020-07-01 00:00:00

abstract：:Nowadays, exceptional advantages of silk fibroin over synthetic and natural polymers have impelled the scientists to application of this biomaterial for tissue engineering purposes. Recently, we showed that embedding natural degummed silk fibers in regenerated Bombyx mori silk-based scaffold significantly increases th...

journal_title：Journal of biomaterials applications

authors： Mobini S,Taghizadeh-Jahed M,Khanmohammadi M,Moshiri A,Naderi MM,Heidari-Vala H,Ashrafi Helan J,Khanjani S,Springer A,Akhondi MM,Kazemnejad S

更新日期：2016-01-01 00:00:00

abstract：:In this study, a novel bilayer scaffold composed of electrospun polycaprolactone and poly(lacto-co-glycolic acid) (PCL/PLGA) membrane and glutaraldehyde (3.5% v/v) cross-linked chitosan/gelatin hydrogel was fabricated using two methods: electrospinning of the membrane onto the lyophilized hydrogel (BS-1) and membrane ...

journal_title：Journal of biomaterials applications

authors： Franco RA,Min YK,Yang HM,Lee BT

更新日期：2013-01-01 00:00:00

abstract：:Phenylalanine ethyl ester (PAE)-alginate (Alg) conjugate (PAE-Alg, PEA) was synthesized and formation of an amide bond between PAE and Alg was confirmed by Fourier transformed-infrared and (1)H nuclear magnetic resonance spectroscopy. The degree of PAE substitution was 3.5-4.7 (PAE group per hundred sugar residues of ...

journal_title：Journal of biomaterials applications

authors： Zhang P,Zhao SR,Li JX,Hong L,Raja MA,Yu LJ,Liu CG

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:A functionalized graphene oxide-based thermosensitive hydrogel loaded with docetaxel for intratumoral delivery was designed to enhance therapeutic efficacy and alleviate system toxicity. METHODS:First, graphene oxide was functionalized with chitosan to acquire high stability in physiological solutions. And the...

journal_title：Journal of biomaterials applications

authors： Zhu X,Zhang Y,Huang H,Zhang H,Hou L,Zhang Z

更新日期：2016-03-01 00:00:00

abstract：:Compounds of a silicone elastomer suitable for preparing maxillofacial prostheses, reinforced with various amounts of silica powder, have been studied for their mechanical response and wetting properties in terms of contact angle. Tensile strength and elongation at break showed an increase with increasing silica volum...

journal_title：Journal of biomaterials applications

authors： Andreopoulos AG,Evangelatou M,Tarantili PA

更新日期：1998-07-01 00:00:00

abstract：:Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series of N-alkyl-substituted linear polyethylenimine (CP) polymers have been synthesized, characterized, and investigated about how degree of substitution (hydrophobi...

journal_title：Journal of biomaterials applications

authors： Bansal R,Kumar P

更新日期：2017-07-01 00:00:00

abstract：:Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...

journal_title：Journal of biomaterials applications

authors： Lusvardi G,Malavasi G,Menabue L,Menziani MC,Pedone A,Segre U,Aina V,Perardi A,Morterra C,Boccafoschi F,Gatti S,Bosetti M,Cannas M

更新日期：2008-05-01 00:00:00

abstract：:Bone tissue engineering, which relies on the interactions between stem cells and suitable scaffold materials, represents a highly desirable alternative to currently used allograft or autograft strategies for the treatment of bone defects caused by injury or disease, with one of the major challenges being to generate s...

journal_title：Journal of biomaterials applications

authors： Feng J,Chong M,Chan J,Zhang Z,Teoh SH,Thian ES

更新日期：2014-07-01 00:00:00

abstract：:Bone tissue is dependent on an efficient blood supply to ensure delivery of nutrients and oxygen. One method to acquire a vascular-engineered bone tissue could be the use of an angiogenic gene-activated scaffold. In the current study, porous chitosan/hydroxyapatite (C/HA) scaffolds were fabricated via freeze-drying wi...

journal_title：Journal of biomaterials applications

authors： Koç A,Finkenzeller G,Elçin AE,Stark GB,Elçin YM

更新日期：2014-11-01 00:00:00

abstract：:We assess the effects of chemical processing, ethylene oxide sterilization, and threading on bone surface and mechanical properties of bovine undecalcified bone screws. In addition, we evaluate the possibility of manufacturing bone screws with predefined dimensions. Scanning electronic microscopic images show that che...

journal_title：Journal of biomaterials applications

authors： Haje DP,Volpon JB,Moro CA

更新日期：2009-03-01 00:00:00

abstract：:The effect of an ampholytic surfactant on the swelling properties of polymeric materials was studied, using various swelling liquids. Tablets were prepared consisting of hydroxypropyl methylcellulose, poly(oxyethylene) and sodium alginate. Tego betain was the non-ionic surfactant used as an additive in a series of sam...

journal_title：Journal of biomaterials applications

authors： Vlachou M,Hani N,Efentakis M,Tarantili PA,Andreopoulos AG

更新日期：2000-07-01 00:00:00

abstract：:To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic fu...

journal_title：Journal of biomaterials applications

authors： Shi X,Fang Q,Ding M,Wu J,Ye F,Lv Z,Jin J

更新日期：2016-02-01 00:00:00