Microspheres of carboxymethyl chitosan, sodium alginate and collagen for a novel hemostatic in vitro study.

Abstract:

:To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic function experiment, it was found that CSCM could facilitate platelet adherence, platelet aggregation, and platelet activation in vitro. Besides, the maximum swelling of CSCM submerged in PBS for 50 min was over 300% of that exhibited by commercial hemostatic compound microporous polysaccharide haemostatic powder (CMPHP). In addition, CSCM exhibited good biodegradability and non-cytotoxicity. These results demonstrated that CSCM may be useful in platelet plug formation, and this study would provide important information for further research on hemostasis experiment in vivo.

journal_name

J Biomater Appl

authors

Shi X,Fang Q,Ding M,Wu J,Ye F,Lv Z,Jin J

doi

10.1177/0885328215618354

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

1092-102

issue

7

eissn

0885-3282

issn

1530-8022

pii

0885328215618354

journal_volume

30

pub_type

杂志文章
  • Polyelectrolyte based molecular carriers: the role of self-assembled proteins in permeability properties.

    abstract::Polyelectrolyte capsules are seen as promising nanotechnology based drug delivery systems. In previous works, we have demonstrated the possibility to fabricate bio-activated surface layer containing capsules with improved features in terms of biocompatibility. In this study, we have characterized the permeability prop...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328212446358

    authors: Habibi N,Pastorino L,Sandoval OH,Ruggiero C

    更新日期:2013-08-01 00:00:00

  • In vivo study of a biodegradable orthopedic screw (MgYREZr-alloy) in a rabbit model for up to 12 months.

    abstract::Biodegradable magnesium-based implants are currently being developed for use in orthopedic applications. The aim of this study was to investigate the acute, subacute, and chronic local effects on bone tissue as well as the systemic reactions to a magnesium-based (MgYREZr-alloy) screw containing rare earth elements. Th...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328212472215

    authors: Waizy H,Diekmann J,Weizbauer A,Reifenrath J,Bartsch I,Neubert V,Schavan R,Windhagen H

    更新日期:2014-01-01 00:00:00

  • Poly (γ-glutamic acid)/beta-TCP nanocomposites via in situ copolymerization: Preparation and characterization.

    abstract::A series biodegradable poly (γ-glutamic acid)/beta-tricalcium phosphate (γ-PGA/TCP) nanocomposites were prepared which were composed of poly-γ-glutamic acid polymerized in situ with β-tricalcium phosphate and physiochemically characterized as bone graft substitutes. The particle size via dynamic light scattering, the ...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328216632444

    authors: Shu XL,Shi QS,Feng J,Yang YH,Zhou G,Li WR

    更新日期:2016-07-01 00:00:00

  • Brushite-based calcium phosphate cement with multichannel hydroxyapatite granule loading for improved bone regeneration.

    abstract::In this work, we report brushite-based calcium phosphate cement (CPC) system to enhance the in vivo biodegradation and tissue in-growth by incorporation of micro-channeled hydroxyapatite (HAp) granule and silicon and sodium addition in calcium phosphate precursor powder. Sodium- and silicon-rich calcium phosphate powd...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328215601938

    authors: Sarkar SK,Lee BY,Padalhin AR,Sarker A,Carpena N,Kim B,Paul K,Choi HJ,Bae SH,Lee BT

    更新日期:2016-01-01 00:00:00

  • Enhancement of CRF-PEEK osseointegration by plasma-sprayed hydroxyapatite: A rabbit model.

    abstract::Carbon-fibre-reinforced polyether ether ketone (CFR-PEEK) exhibits excellent biomechanical properties as it has an elastic modulus similar to bone. However, CFR-PEEK displays inferior biocompatibility compared with titanium alloy and coating techniques are therefore of interest in order to improve integration. In this...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328214521669

    authors: Suska F,Omar O,Emanuelsson L,Taylor M,Gruner P,Kinbrum A,Hunt D,Hunt T,Taylor A,Palmquist A

    更新日期:2014-08-01 00:00:00

  • Structure and permeability of dialysis membranes sterilized by various methods.

    abstract::Appropriate design of dialysis membranes requires correct values of structural parameters such as pore radius, surface porosity, water content and tortuosity. It is impossible, however, to find the pore radius of dialysis membranes using a mercury porosimeter or an electron microscope because the pores are only severa...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532828900400201

    authors: Sakai K

    更新日期:1989-10-01 00:00:00

  • Properties of zinc releasing surfaces for clinical applications.

    abstract::Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328207079731

    authors: Lusvardi G,Malavasi G,Menabue L,Menziani MC,Pedone A,Segre U,Aina V,Perardi A,Morterra C,Boccafoschi F,Gatti S,Bosetti M,Cannas M

    更新日期:2008-05-01 00:00:00

  • Strontium-substituted calcium sulfate hemihydrate/hydroxyapatite scaffold enhances bone regeneration by recruiting bone mesenchymal stromal cells.

    abstract::Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate resorption rate is of great significance for treating bone defects. To achieve this aim, strontium-substituted calcium sulfate hemihydrate (Sr-CSH) and hydroxyapatite (HA) were mixed to develop a novel composite. Sr-CSH containing 5...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328220915816

    authors: Chang H,Xiang H,Yao Z,Yang S,Tu M,Zhang X,Yu B

    更新日期:2020-07-01 00:00:00

  • Melanin-containing hydrogel intraocular lenses: a histopathological study in animal eyes.

    abstract::Poly(2-hydroxyethyl methacrylate) hydrogel intraocular lenses, containing adrenochrome-melanin, were manufactured and implanted in animal eyes in order to assess the effect of melanin upon (a) biocompatibility of implants with the eye tissues, and (b) fibrous proliferation of lens epithelium responsible for the opacif...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532829500900305

    authors: Chirila TV,Constable IJ,Vijayasekaran S,Ben-Hun J

    更新日期:1995-01-01 00:00:00

  • Functionalized graphene oxide-based thermosensitive hydrogel for near-infrared chemo-photothermal therapy on tumor.

    abstract:PURPOSE:A functionalized graphene oxide-based thermosensitive hydrogel loaded with docetaxel for intratumoral delivery was designed to enhance therapeutic efficacy and alleviate system toxicity. METHODS:First, graphene oxide was functionalized with chitosan to acquire high stability in physiological solutions. And the...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328215619583

    authors: Zhu X,Zhang Y,Huang H,Zhang H,Hou L,Zhang Z

    更新日期:2016-03-01 00:00:00

  • A novel human-like collagen hemostatic sponge with uniform morphology, good biodegradability and biocompatibility.

    abstract::Biodegradable sponges, as a promising hemostatic biomaterial, has been clinically required over the past decades. Current hemostatic sponges are generally prepared by crosslinking and freeze-drying, but the quality control or biocompatibility is often unsatisfactory due to the freezing-caused morphological non-uniform...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328216687663

    authors: Jiang X,Wang Y,Fan D,Zhu C,Liu L,Duan Z

    更新日期:2017-03-01 00:00:00

  • Phase stability and rapid consolidation of hydroxyapatite-zirconia nano-coprecipitates made using continuous hydrothermal flow synthesis.

    abstract::A rapid and continuous hydrothermal route for the synthesis of nano-sized hydroxyapatite rods co-precipitated with calcium-doped zirconia nanoparticles using a superheated water flow at 450°C and 24.1 MPa as a crystallizing medium is described. Hydroxyapatite and calcium-doped zirconia phases in the powder mixtures co...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328212444483

    authors: Chaudhry AA,Yan H,Viola G,Reece MJ,Knowles JC,Gong K,Rehman I,Darr JA

    更新日期:2012-07-01 00:00:00

  • Combination of an allogenic and a xenogenic bone substitute material with injectable platelet-rich fibrin - A comparative in vitro study.

    abstract::The aim of the in vitro study was a comparison of an allogenic (ABSM) and a xenogenic bone substitute material (XBSM) with and without injectable platelet-rich fibrin (ABSM-i-PRF & XBSM-i-PRF) on cell characteristics of human osteoblasts (HOB). Here, ABSM and XBSM (+ i-PRF = test; - i-PRF = control) were incubated wit...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328220914407

    authors: Kyyak S,Blatt S,Pabst A,Thiem D,Al-Nawas B,Kämmerer PW

    更新日期:2020-07-01 00:00:00

  • Influence of the selection of the suture material on the mechanical behavior of a biomaterial to be employed in the construction of implants. Part 2: Porcine pericardium.

    abstract::Using a hydraulic stress simulator, the mechanical behavior of the porcine pericardium used in the construction of cardiac valve leaflets was characterized following the same procedure employed with calf pericardium in Part 1 of this study. One hundred fifty pairs of tissue samples were subjected to tensile testing to...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1106/3JXM-UTPN-PXTG-72DT

    authors: García Páez JM,Carrera A,Herrero EJ,Millán I,Rocha A,Cordón A,Sainz N,Mendez J,Castillo-Olivares JL

    更新日期:2001-07-01 00:00:00

  • The adhesion and proliferation of bone marrow-derived mesenchymal stem cells promoted by nanoparticle surface.

    abstract::This study's aim consists of evaluating the adhesion and proliferation of mesenchymal stem cells (MSCs) derived from rat bone marrow on nanoparticle Titanium (Ti) surface. Hence, passage 3 MSCs were, respectively, seeded on nanoparticle Ti and pure Ti surfaces and then cultured for 32 h. Cell morphology and viability ...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328211414750

    authors: Chen L,Sun J,Zhu Z,Wu K,Li W,Liu H,Xu S

    更新日期:2013-01-01 00:00:00

  • Cell survival and proliferation after encapsulation in a chemically modified Pluronic(R) F127 hydrogel.

    abstract::Pluronic® F127 is a biocompatible, injectable, and thermoresponsive polymer with promising biomedical applications. In this study, a chemically modified form, i.e., Pluronic ALA-L with tailored degradation rate, was tested as an encapsulation vehicle for osteoblastic cells. UV cross-linking of the modified polymer res...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328211427774

    authors: Lippens E,Swennen I,Gironès J,Declercq H,Vertenten G,Vlaminck L,Gasthuys F,Schacht E,Cornelissen R

    更新日期:2013-03-01 00:00:00

  • Effectiveness of antibacterial copper additives in silicone implants.

    abstract::Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328212441957

    authors: Gosau M,Bürgers R,Vollkommer T,Holzmann T,Prantl L

    更新日期:2013-08-01 00:00:00

  • Biocompatibility properties of surface-modified poly(dimethylsiloxane) for urinary applications.

    abstract::An electronic sensor system for urinary bladder pressure monitoring requires an imbedding into a biocompatible, flexible, and liquid-impermeable material. Poly(dimethylsiloxane) (PDMS) was selected in the present set-up as packaging material because it fulfills the abovementioned requirements. However, the surface of ...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328211422119

    authors: Lippens E,De Smet N,Schauvliege S,Martens A,Gasthuys F,Schacht E,Cornelissen R

    更新日期:2013-02-01 00:00:00

  • Physical properties and blood compatibility of poly(urethaneamideimide) and poly(urethaneureas) with aliphatic side chains.

    abstract::The synthesis, tensile strength, thermostability and hydrophilicity of the poly(urethaneamideimide) and the poly(urethaneureas) with N-aliphatic side chains are presented. These elastomers were compared in blood compatibility with determination of the common indices and with immunologic tests of the beta-thromboglobul...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1106/TBUW-TWW9-EC7X-YA3H

    authors: Calusinski G,Masiulanis B,Jurkowski P

    更新日期:2000-10-01 00:00:00

  • Effect of platelet-rich plasma on the in vitro proliferation and osteogenic differentiation of human mesenchymal stem cells on distinct calcium phosphate scaffolds: the specific surface area makes a difference.

    abstract::The in vitro effect of platelet-rich plasma (PRP) on cell loading, proliferation, and osteogenic differentiation of human mesenchymal stem cells (MSC) is assessed on distinct resorbable and synthetic calcium phosphate scaffolds. A high specific surface area scaffold composed of calcium-deficient hydroxyapatite (CDHA; ...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328207088269

    authors: Kasten P,Vogel J,Beyen I,Weiss S,Niemeyer P,Leo A,Lüginbuhl R

    更新日期:2008-09-01 00:00:00

  • Impact of polyelectrolytes and their corresponding multilayers to human primary endothelial cells.

    abstract::The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328212437610

    authors: Nolte A,Hossfeld S,Schroeppel B,Mueller A,Stoll D,Walker T,Wendel HP,Krastev R

    更新日期:2013-07-01 00:00:00

  • Development of a microporous compliant small bore vascular graft.

    abstract:PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532829501000207

    authors: Edwards A,Carson RJ,Bowald S,Quist WC

    更新日期:1995-10-01 00:00:00

  • Periodontal ligament versus bone marrow mesenchymal stem cells in combination with Bio-Oss scaffolds for ectopic and in situ bone formation: A comparative study in the rat.

    abstract::The aim of this study was to compare the osteogenic effects of periodontal ligament stem cells (PDLSCs) versus bone marrow mesenchymal stem cells (BMMSCs) in combination with Bio-Oss scaffolds on subcutaneous and critical-size defects in the immunodeficient rat calvarium. PDLSCs and BMMSCs were obtained from the same ...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328214521846

    authors: Yu BH,Zhou Q,Wang ZL

    更新日期:2014-08-01 00:00:00

  • Engineered polymeric amphiphiles self-assembling into nanostructures and acting as efficient gene and drug carriers.

    abstract::Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series of N-alkyl-substituted linear polyethylenimine (CP) polymers have been synthesized, characterized, and investigated about how degree of substitution (hydrophobi...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328217710125

    authors: Bansal R,Kumar P

    更新日期:2017-07-01 00:00:00

  • Plastics in medical applications.

    abstract::Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532828700200305

    authors: Lantos PR

    更新日期:1988-01-01 00:00:00

  • Characterization of a new composite PMMA-HA/Brushite bone cement for spinal augmentation.

    abstract::Calcium phosphate fillers have been shown to increase cement osteoconductivity, but have caused drawbacks in cement properties. Hydroxyapatite and Brushite were introduced in an acrylic two-solution cement at varying concentrations. Novel composite bone cements were developed and characterized using rheology, injectab...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328214544770

    authors: Aghyarian S,Rodriguez LC,Chari J,Bentley E,Kosmopoulos V,Lieberman IH,Rodrigues DC

    更新日期:2014-11-01 00:00:00

  • Hemodynamic predictors for weaning patients from ventricular assist devices (VADs).

    abstract::In order to find hemodynamic parameters that can accurately predict whether patients can be successfully weaned from ventricular assist devices (VADs), we studied data from 17 patients supported with Pierce-Donachy VADs [11 left VAD (LVAD); 6 right VAD (RVAD)] following cardiogenic shock for periods from 1.3 to 22 day...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532829000400403

    authors: Termuhlen DF,Swartz MT,Ruzevich SA,Reedy JE,Pennington DG

    更新日期:1990-04-01 00:00:00

  • Anticoagulant activity of immobilized heparin on the polypropylene nonwoven fabric surface depending upon the pH of processing environment.

    abstract::Antenna coupling microwave plasma enables a highly oxidative treatment of the outmost surface of polypropylene (PP) nonwoven fabric within a short time period. Subsequently, grafting copolymerization with acrylic acid (AAc) makes the plasma-treated fabric durably hydrophilic and excellent in water absorbency. With hig...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1106/088532802030478

    authors: Tyan YC,Liao JD,Wu YT,Klauser R

    更新日期:2002-10-01 00:00:00

  • An arterial prosthesis from Argentina: the Barone Microvelour arterial graft.

    abstract::The manufacture of a polyester vascular prosthesis in the southern hemisphere is a new development in the global dissemination of this maturing technology. Hence the recent introduction of the Barone Microvelour arterial graft from Argentina has highlighted the need for a comparative in vitro and in vivo study to comp...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/088532828800300302

    authors: Torché D,Guidoin R,Boyer D,Marceau D,Marois Y,Debille E,Lacombe J,King M

    更新日期:1989-01-01 00:00:00

  • Montmorillonite-alginate nanocomposites as a drug delivery system: intercalation and in vitro release of vitamin B1 and vitamin B6.

    abstract::Sustained intestinal delivery of thiamine hydrochloride (Vitamin B(1); VB(1)) and pyridoxine hydrochloride (Vitamin B(6); VB(6)) seems to be a feasible alternative to existing therapy. The vitamins (VB(1)/VB(6)) intercalated in montmorillonite (MMT) and intercalated VB(1)/VB(6)-MMT hybrid is further used for synthesis...

    journal_title:Journal of biomaterials applications

    pub_type: 杂志文章

    doi:10.1177/0885328209344003

    authors: Kevadiya BD,Joshi GV,Patel HA,Ingole PG,Mody HM,Bajaj HC

    更新日期:2010-08-01 00:00:00