Abstract:
:Gold nanomaterials possess unique physical and chemical properties, which attracted much attention in recent years. As a new type of gold nanomaterials, gold nanostars (GNSTs) have been prepared and characterized in this study. GNSTs under near-infrared (NIR) light irradiation can exert not only cancer photothermal therapy via heat production but also photodynamic therapy via generation of reactive oxygen species. GNSTs were able to enter the cytoplasm as well as nuclei of human breast michigan cancer foundation-7 (MCF-7) cells. Under NIR light irradiation, GNSTs caused more severe DNA damage, arrest the cell cycle in G0/G1 phase, and reduce more cellular glutathione level, causing more severe apoptosis and cell death in vitro. Intratumoral injection of GNSTs with NIR light irradiation significantly inhibited tumor growth in vivo. In addition, GNSTs were demonstrated to be a contrast agent for X-ray imaging. All the in vitro and in vivo results showed that GNSTs can be used for the potential diagnosis and medical treatment of cancer.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Wang L,Meng D,Hao Y,Zhao Y,Li D,Zhang B,Zhang Y,Zhang Zdoi
10.1177/0885328215594481subject
Has Abstractpub_date
2015-11-01 00:00:00pages
547-57issue
5eissn
0885-3282issn
1530-8022pii
0885328215594481journal_volume
30pub_type
杂志文章abstract::In this paper, the authors describe a novel type of hydrogel coating prepared from the copolymer of human serum albumin and oxidized dextran. The material was designed as a hydrogel sealant for polyester (Dacron®)-based vascular grafts. Dextran was chosen as a coating material due to its anti-thrombogenic properties. ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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abstract::Nanodrug delivery systems have been widely researched to achieve efficient antitumor drug delivery. However, the controlled drug delivery at tumor cells remains the main challenge for antitumor therapy. Herein, a pH and reduction-responsive nanocarrier based on green tea polyphenols was employed as a smart excipient f...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220924539
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abstract::Transarterial embolization is an established minimally invasive treatment for solid tumors. Unintended inflammation, foreign body reactions and ischemia-triggered neoangiogenesis are clinical drawbacks of permanent embolic materials. The aim of the current study was to characterize a new type of biodegradable starch m...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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abstract::Cellulose acetate phthalate and Pluronic F-127 combined together (70:30 wt:wt) create a rigid, surface-eroding association polymer. To impart flexibility into the polymer system and allow for a drug delivery film that can contour to varying wound shapes, plasticizers were added. Triethyl citrate or tributyl citrate wa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213480979
更新日期:2014-01-01 00:00:00
abstract::Appropriate design of dialysis membranes requires correct values of structural parameters such as pore radius, surface porosity, water content and tortuosity. It is impossible, however, to find the pore radius of dialysis membranes using a mercury porosimeter or an electron microscope because the pores are only severa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532828900400201
更新日期:1989-10-01 00:00:00
abstract::In this work, we report brushite-based calcium phosphate cement (CPC) system to enhance the in vivo biodegradation and tissue in-growth by incorporation of micro-channeled hydroxyapatite (HAp) granule and silicon and sodium addition in calcium phosphate precursor powder. Sodium- and silicon-rich calcium phosphate powd...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215601938
更新日期:2016-01-01 00:00:00
abstract::The aim of the paper is to obtain and characterize k-carrageenan-chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, and as a possible antitumoral agent in biological studies. We used the CaCO3 template to synthesize non-toxic CaCO3/BSA particles as microtemplates by coprecipitat...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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abstract::Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209359959
更新日期:2011-03-01 00:00:00
abstract::The aim of this study was to investigate the effect of C-Graft particles on formation of new cementum and bone in periodontal bone defects in dog. Healing and tissue change were histologically determined at 2, 4, 8, and 16 weeks. Little bone or cementum formation was observed in the control group. A statistically sign...
journal_title:Journal of biomaterials applications
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更新日期:2009-08-01 00:00:00
abstract::The purpose of this study was to develop a specific targeting magnetic nanoparticle probe for magnetic resonance imaging and therapy in the form of local hyperthermia. Carboxymethyl dextran-coated ultrasmall superparamagnetic iron oxide nanoparticles with carboxyl groups were coupled to cyclic arginine-glycine-asparti...
journal_title:Journal of biomaterials applications
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更新日期:2014-03-01 00:00:00
abstract::The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829200700203
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829501000207
更新日期:1995-10-01 00:00:00
abstract::Compounds of a silicone elastomer suitable for preparing maxillofacial prostheses, reinforced with various amounts of silica powder, have been studied for their mechanical response and wetting properties in terms of contact angle. Tensile strength and elongation at break showed an increase with increasing silica volum...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829801300104
更新日期:1998-07-01 00:00:00
abstract::Poly(2-hydroxyethyl methacrylate) hydrogel intraocular lenses, containing adrenochrome-melanin, were manufactured and implanted in animal eyes in order to assess the effect of melanin upon (a) biocompatibility of implants with the eye tissues, and (b) fibrous proliferation of lens epithelium responsible for the opacif...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829500900305
更新日期:1995-01-01 00:00:00
abstract::The incidence of fractures increases with age. This is partly due to extraosseous factors and partly to the increased fragility of the bone material itself. Ageing adversely affects the "quality" of human bone material, its elastic and ultimate properties. The hypothesis here is that these effects are caused by factor...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1106/5JUJ-TFJ3-JVVA-3RJ0
更新日期:2001-01-01 00:00:00
abstract::The in vitro effect of platelet-rich plasma (PRP) on cell loading, proliferation, and osteogenic differentiation of human mesenchymal stem cells (MSC) is assessed on distinct resorbable and synthetic calcium phosphate scaffolds. A high specific surface area scaffold composed of calcium-deficient hydroxyapatite (CDHA; ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328207088269
更新日期:2008-09-01 00:00:00
abstract::Biodegradable magnesium-based implants are currently being developed for use in orthopedic applications. The aim of this study was to investigate the acute, subacute, and chronic local effects on bone tissue as well as the systemic reactions to a magnesium-based (MgYREZr-alloy) screw containing rare earth elements. Th...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212472215
更新日期:2014-01-01 00:00:00
abstract::The manufacture of a polyester vascular prosthesis in the southern hemisphere is a new development in the global dissemination of this maturing technology. Hence the recent introduction of the Barone Microvelour arterial graft from Argentina has highlighted the need for a comparative in vitro and in vivo study to comp...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
abstract::Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532828700200305
更新日期:1988-01-01 00:00:00
abstract::A new diol, bis[2-(2-hydroxyethyldimethylammonio)ethyl] butylenediphosphate, that contains two phosphatidylcholine analogous moieties in one diol molecule, was synthesized and characterized. The diol together with 1,4-butanediol as chain extender was further incorporated into the propolymer of poly(ethylene oxide) (Mn...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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更新日期:1997-10-01 00:00:00
abstract::In this study, the effects of sodium carbonate (Na(2)CO(3) ) solution with different concentrations (10, 15, 20, and 25 wt%) as liquid phase on the setting time and compressive strength of tricalcium silicate bone cements are investigated. The in vitro bioactivity and degradability of the resultant Ca(3)SiO(5)-Na(2)CO...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328208088714
更新日期:2008-11-01 00:00:00
abstract::Nowadays, exceptional advantages of silk fibroin over synthetic and natural polymers have impelled the scientists to application of this biomaterial for tissue engineering purposes. Recently, we showed that embedding natural degummed silk fibers in regenerated Bombyx mori silk-based scaffold significantly increases th...
journal_title:Journal of biomaterials applications
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更新日期:2016-01-01 00:00:00
abstract::The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212437610
更新日期:2013-07-01 00:00:00
abstract::Biodegradable sponges, as a promising hemostatic biomaterial, has been clinically required over the past decades. Current hemostatic sponges are generally prepared by crosslinking and freeze-drying, but the quality control or biocompatibility is often unsatisfactory due to the freezing-caused morphological non-uniform...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328216687663
更新日期:2017-03-01 00:00:00
abstract::An electronic sensor system for urinary bladder pressure monitoring requires an imbedding into a biocompatible, flexible, and liquid-impermeable material. Poly(dimethylsiloxane) (PDMS) was selected in the present set-up as packaging material because it fulfills the abovementioned requirements. However, the surface of ...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
abstract::Hydroxyapatite (Ca10(PO4)6(OH)2) is widely investigated as an implantable material for hard tissue restoration due to its osteoconductive properties. However, hydroxyapatite in bulk form is limited as its mechanical properties are insufficient for load-bearing orthopedic applications. Attempts have been made to improv...
journal_title:Journal of biomaterials applications
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更新日期:2015-11-01 00:00:00
abstract::Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...
journal_title:Journal of biomaterials applications
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更新日期:2013-08-01 00:00:00
abstract::Among biomaterials used as implants in human body, sutures constitute the largest groups of materials having a huge market exceeding $1.3 billion annually. Sutures are the most widely used materials in wound closure and have been in use for many centuries. With the development of the synthetic absorbable polymer, poly...
journal_title:Journal of biomaterials applications
pub_type: 历史文章,杂志文章,评审
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更新日期:2010-11-01 00:00:00
abstract::Nanohydroxyapatite (nanoHA), due to its chemical properties, has appeared as an exceptionally promising bioceramic to be used as bone regeneration material. Staphylococcus epidermidis have emerged as major nosocomial pathogens associated with infections of implanted medical devices. In this work, the purpose was to st...
journal_title:Journal of biomaterials applications
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更新日期:2014-05-01 00:00:00
abstract::The aim of the in vitro study was a comparison of an allogenic (ABSM) and a xenogenic bone substitute material (XBSM) with and without injectable platelet-rich fibrin (ABSM-i-PRF & XBSM-i-PRF) on cell characteristics of human osteoblasts (HOB). Here, ABSM and XBSM (+ i-PRF = test; - i-PRF = control) were incubated wit...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00