Abstract：
:Aluminum-free glass ionomer cements (GICs) are under development for orthopedic applications, but are limited by their insufficient handling properties. Here, the addition of calcium polyphosphate (CPP) was investigated as an additive to an experimental zinc-silicate glass ionomer cement. A 50% maximum increase in working time was observed with CPP addition, though this was not clinically significant due to the short working times of the starting zinc-silicate GIC. Surprisingly, CPP also improved the mechanical properties, especially the tensile strength which increased by ∼33% after 30 days in TRIS buffer solution upon CPP addition up to 37.5 wt%. This strengthening may have been due to the formation of ionic crosslinks between the polyphosphate chains and polyacrylic acid. Thus, CPP is a potential additive to future GIC compositions as it has been shown to improve handling and mechanical properties. In addition, CPP may stimulate new bone growth and provide the ability for drug delivery, which are desirable modifications for an orthopedic cement.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Valliant EM,Gagnier D,Dickey BT,Boyd D,Filiaggi MJdoi
10.1177/0885328215568985subject
Has Abstractpub_date
2015-07-01 00:00:00pages
61-70issue
1eissn
0885-3282issn
1530-8022pii
0885328215568985journal_volume
30pub_type
杂志文章abstract：:Using a hydraulic stress simulator, the mechanical behavior of the porcine pericardium used in the construction of cardiac valve leaflets was characterized following the same procedure employed with calf pericardium in Part 1 of this study. One hundred fifty pairs of tissue samples were subjected to tensile testing to...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1106/3JXM-UTPN-PXTG-72DT
更新日期：2001-07-01 00:00:00
abstract：:The objective of this study is to evaluate the osteoconductivity and bioactivity of the Bonelike graft in repairing surgical cystic bone defects. Bonelike is implanted in 11 patients, aged between 24 and 53 years with a mean age of 36 years, consisting of 5 men and 6 women. According to the standard follow up protocol...
journal_title：Journal of biomaterials applications
pub_type： 临床试验,杂志文章
doi：10.1177/0885328207078260
更新日期：2008-01-01 00:00:00
abstract：:Tendon tears are a relevant concern for today's national health systems because of their social impact and high recurrence rate. The current gold standard for fixing tendon tears is surgical repair; however, this strategy is not able to fully re-establish tendon integrity and functionality. Tissue engineering approach...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218779846
更新日期：2018-07-01 00:00:00
abstract：:Injectable thermo-sensitive hydrogels have a potential application in bone tissue engineering for their sensitivities and minimal invasive properties. Human dental pulp stem cells have been considered a promising tool for tissue reconstruction. The objective of this study was to investigate the proliferation and osteo...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216661566
更新日期：2016-09-01 00:00:00
abstract：:Biodegradable sponges, as a promising hemostatic biomaterial, has been clinically required over the past decades. Current hemostatic sponges are generally prepared by crosslinking and freeze-drying, but the quality control or biocompatibility is often unsatisfactory due to the freezing-caused morphological non-uniform...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216687663
更新日期：2017-03-01 00:00:00
abstract：:Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532828700200305
更新日期：1988-01-01 00:00:00
abstract：:Polypropylene meshes are standard for hernia repair. Matrix metalloproteinases play a central role in inflammation. To reduce the inflammatory response and improve remodelling with an associated reduction of hernia recurrence, we modified polypropylene meshes by nanofibre coating and saturation with the broad-spectrum...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218759043
更新日期：2018-05-01 00:00:00
abstract：:The relative surface charge and free energy of forty-one coagulase-negative staphylococci were found to be normally distributed; therefore, they can be considered a homogeneous group under strict statistical criteria. The adherence of these bacteria to eight different biomaterials (seven synthetic and one biologic) wa...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829200700203
更新日期：1992-10-01 00:00:00
abstract：:Dicalcium phosphate dihydrate particles functionalized with triethyleneglycol dimethacrylate were synthesized and added to a photocurable mixture of bisphenol-A glycidyl dimethacrylate and triethyleneglycol dimethacrylate with the purpose of developing a resin composite capable of releasing calcium and phosphate ions ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216680116
更新日期：2017-01-01 00:00:00
abstract：:The manufacture of a polyester vascular prosthesis in the southern hemisphere is a new development in the global dissemination of this maturing technology. Hence the recent introduction of the Barone Microvelour arterial graft from Argentina has highlighted the need for a comparative in vitro and in vivo study to comp...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532828800300302
更新日期：1989-01-01 00:00:00
abstract：:A biodegradable polylactic acid composite containing tricalcium phosphate microsphere was fabricated. The composite exhibited enhanced biocompatibility and a well-interconnected porous structure that enabled tissue ingrowth after degradation. The tricalcium phosphate microspheres had an average size of 106 ± 43 μm and...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218763660
更新日期：2018-05-01 00:00:00
abstract：:In this work, the role of shock wave-induced increase of bone morphogenetic proteins in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a bone morphogenetic protein antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experime...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328214541974
更新日期：2014-11-01 00:00:00
abstract：:This investigation describes the synthesis and in vitro evaluation of cationic hydrogel sub-microparticles based on polydimethylaminoethylmethacrylate for oral insulin delivery. Polymerization of dimethylaminoethylmethacrylate was carried out in aqueous medium with potassium persulfate as the initiator. Quaternization...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212437392
更新日期：2013-07-01 00:00:00
abstract：:Magnesium-based alloys exhibit biodegradable, biocompatible and excellent mechanical properties which enable them to serve as ideal candidate biomedical materials. In particular, their biodegradable ability helps patients to avoid a second surgery. The corrosion rate, however, is too rapid to sustain the healing proce...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章,评审
doi：10.1177/0885328219834656
更新日期：2019-05-01 00:00:00
abstract：:Solvent-based methods are commonly employed for the production of polyester-based samples and coatings in both medical device production and research. The influence of solvent casting and subsequent drying time was studied using thermal analysis, spectroscopy and weight measurement for four grades of 50 : 50 poly(lact...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328210376997
更新日期：2012-01-01 00:00:00
abstract：:Transarterial embolization is an established minimally invasive treatment for solid tumors. Unintended inflammation, foreign body reactions and ischemia-triggered neoangiogenesis are clinical drawbacks of permanent embolic materials. The aim of the current study was to characterize a new type of biodegradable starch m...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328217746674
更新日期：2018-02-01 00:00:00
abstract：:A series of cellulose/soy protein isolate (SPI) sponges was prepared using a freeze-drying process. The effect of the SPI content on the structure of the sponges was characterized by Fourier transform infrared spectrometry (FT-IR), X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM). It showed that...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208099337
更新日期：2010-02-01 00:00:00
abstract：:Three types of commercially available ultra-high molecular weight polyethylene (UHMWPE) acetabular cups currently used in total hip arthroplasty have been studied by means of Raman micro-spectroscopy to unfold the microstructural modification induced by the oxidative degradation after accelerated aging with and withou...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328214548693
更新日期：2015-01-01 00:00:00
abstract：:Calcium polyphosphate is a biodegradable bone substitute. It remains a challenge to prepare porous calcium polyphosphate with desired gradient porous structures. In this study, a modified one-step gravity sintering method was used to prepare calcium polyphosphate scaffolds with desired-gradient-pore-size distribution....
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215608335
更新日期：2016-02-01 00:00:00
abstract：:A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to pha...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212460289
更新日期：2013-09-01 00:00:00
abstract：:Calcium phosphate fillers have been shown to increase cement osteoconductivity, but have caused drawbacks in cement properties. Hydroxyapatite and Brushite were introduced in an acrylic two-solution cement at varying concentrations. Novel composite bone cements were developed and characterized using rheology, injectab...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328214544770
更新日期：2014-11-01 00:00:00
abstract：:The aim of this pilot study was to evaluate the bioactive, surface-coated polycaprolactone-co-lactide scaffolds as bone implants in a tibia critical size defect model. Polycaprolactone-co-lactide scaffolds were coated with collagen type I and chondroitin sulfate and 30 piled up polycaprolactone-co-lactide scaffolds we...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212471409
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829501000207
更新日期：1995-10-01 00:00:00
abstract：:Understanding the structure-function relationship in biomaterial constructs is critical in optimizing biological outcomes. For ensheathed structures such as peripheral nerve, engineering implantable tissue substitutes has been challenging. This is due to a unique geometry of thin-walled microtube arrays composed mostl...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218804338
更新日期：2018-10-01 00:00:00
abstract：:The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章,评审
doi：10.1177/088532829701200104
更新日期：1997-07-01 00:00:00
abstract：:The synthesis, tensile strength, thermostability and hydrophilicity of the poly(urethaneamideimide) and the poly(urethaneureas) with N-aliphatic side chains are presented. These elastomers were compared in blood compatibility with determination of the common indices and with immunologic tests of the beta-thromboglobul...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1106/TBUW-TWW9-EC7X-YA3H
更新日期：2000-10-01 00:00:00
abstract：:The aim of this work was to study the cytotoxicity of different fractions of gold nanoparticles prepared by ultrasonic spray pyrolysis from gold scrap. The target cells were rat thymocytes, as a type of nonproliferating cells, and L929 mouse fibroblasts, as a type of continuous proliferating cells. Fractions 1 and 2, ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328210377536
更新日期：2012-01-01 00:00:00
abstract：:A rapid and continuous hydrothermal route for the synthesis of nano-sized hydroxyapatite rods co-precipitated with calcium-doped zirconia nanoparticles using a superheated water flow at 450°C and 24.1 MPa as a crystallizing medium is described. Hydroxyapatite and calcium-doped zirconia phases in the powder mixtures co...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212444483
更新日期：2012-07-01 00:00:00
abstract：:Compounds of a silicone elastomer suitable for preparing maxillofacial prostheses, reinforced with various amounts of silica powder, have been studied for their mechanical response and wetting properties in terms of contact angle. Tensile strength and elongation at break showed an increase with increasing silica volum...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829801300104
更新日期：1998-07-01 00:00:00
abstract：:Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328217725203
更新日期：2017-10-01 00:00:00
