Abstract：
:The objective of this study is to evaluate the osteoconductivity and bioactivity of the Bonelike graft in repairing surgical cystic bone defects. Bonelike is implanted in 11 patients, aged between 24 and 53 years with a mean age of 36 years, consisting of 5 men and 6 women. According to the standard follow up protocols, radiological examinations are performed and Bonelike/bone retrieved samples have been analyzed histologically using non-decalcified sections obtained perpendicular to bone length axis. Radiographic examination and histological results clearly demonstrate an extensive new bone formation apposed on Bonelike granules with a significant degree of maturation. These clinical applications in maxillary bone defects indicate perfect bone bonding between new bone formed and Bonelike granules, along with partial surface biodegradation. This quick and effective osteoconductive response from Bonelike may reduce the time needed to reconstruct the bone defected area of patients.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Sousa RC,Lobato JV,Maurício AC,Hussain NS,Botelho CM,Lopes MA,Santos JDdoi
10.1177/0885328207078260subject
Has Abstractpub_date
2008-01-01 00:00:00pages
373-85issue
4eissn
0885-3282issn
1530-8022pii
0885328207078260journal_volume
22pub_type
临床试验,杂志文章abstract：:The aim of the paper is to obtain and characterize k-carrageenan-chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, and as a possible antitumoral agent in biological studies. We used the CaCO3 template to synthesize non-toxic CaCO3/BSA particles as microtemplates by coprecipitat...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328215603797
更新日期：2016-01-01 00:00:00
abstract：:In this study, the effects of sodium carbonate (Na(2)CO(3) ) solution with different concentrations (10, 15, 20, and 25 wt%) as liquid phase on the setting time and compressive strength of tricalcium silicate bone cements are investigated. The in vitro bioactivity and degradability of the resultant Ca(3)SiO(5)-Na(2)CO...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208088714
更新日期：2008-11-01 00:00:00
abstract：:Biodegradable magnesium-based implants are currently being developed for use in orthopedic applications. The aim of this study was to investigate the acute, subacute, and chronic local effects on bone tissue as well as the systemic reactions to a magnesium-based (MgYREZr-alloy) screw containing rare earth elements. Th...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212472215
更新日期：2014-01-01 00:00:00
abstract：:Appropriate design of dialysis membranes requires correct values of structural parameters such as pore radius, surface porosity, water content and tortuosity. It is impossible, however, to find the pore radius of dialysis membranes using a mercury porosimeter or an electron microscope because the pores are only severa...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532828900400201
更新日期：1989-10-01 00:00:00
abstract：:A biodegradable polylactic acid composite containing tricalcium phosphate microsphere was fabricated. The composite exhibited enhanced biocompatibility and a well-interconnected porous structure that enabled tissue ingrowth after degradation. The tricalcium phosphate microspheres had an average size of 106 ± 43 μm and...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218763660
更新日期：2018-05-01 00:00:00
abstract：:Excessive demineralization in osteoporotic bones impairs its self-regeneration potential following a defect/fracture and is of great concern among the aged population. In this context, implants with inherent osteogenic ability loaded with therapeutic ions like Strontium (Sr2+) may bring forth promising outcomes. Micro...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216647197
更新日期：2016-10-01 00:00:00
abstract：:The animal immune response against Galα1,3-Galβ1-4GlcNAc-R(α-Gal) epitopes gives an important cause for the failure of glutaraldehyde(GA)-fixed cardiac xenografts. This study aimed to assess the in vivo effect of our novel combined anticalcification treatment, which includes immunologic modification, using α1,3-galact...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328214552710
更新日期：2015-02-01 00:00:00
abstract：:The carcinogenic potential of asbestos has led to the development of non-asbestos materials for use as casting ring liners. Cellulose paper are replacing asbestos paper. The brass die and crown were made to produce full crowns. The standardized wax pattern was replicated twenty-nine times. Two grooves were marked on t...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532820001400406
更新日期：2000-04-01 00:00:00
abstract：:In this study, a novel bilayer scaffold composed of electrospun polycaprolactone and poly(lacto-co-glycolic acid) (PCL/PLGA) membrane and glutaraldehyde (3.5% v/v) cross-linked chitosan/gelatin hydrogel was fabricated using two methods: electrospinning of the membrane onto the lyophilized hydrogel (BS-1) and membrane ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328211416527
更新日期：2013-01-01 00:00:00
abstract：:Novel in situ polymerizable liquid three-arm biodegradable oligomeric polyesters based upon glycolic acid (GA), L-lactic acid (LLA), and their copolymers are synthesized and characterized. Injectable and in situ curable polymer neat resins and their composites formulated with bioabsorbable beta-tricalcium phosphate ar...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328206068691
更新日期：2007-07-01 00:00:00
abstract：:A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to pha...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328212460289
更新日期：2013-09-01 00:00:00
abstract：:Medical sheets are useful in surgically repair vascular disease. To avoid long-term side effects, they are to be replaced with regenerated tissue after implantation. Silk fibroin is a fibrous protein secreted by silkworm. The advantage of silk fibroin is its biocompatibility and has been used as regenerative artificia...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328220928660
更新日期：2020-06-02 00:00:00
abstract：:Single nanofibers with chemical and functional properties consistent with artery extracellular matrix nanofibers were produced by electrospinning. Using weight ratios to mimic artery extracellular matrix, five materials were tested: (1) Collagen type I, (2) Collagen type I + Collagen type III, (3) Collagen type I + po...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328213477893
更新日期：2014-01-01 00:00:00
abstract：:NiTi alloy is used as a biomaterial due to its pseudoelastic behaviour. It exhibits a great potential in dental and orthopedic applications where constant correcting loads are required. In order to use such materials, it is necessary to investigate the effect of the cyclic straining upon the transformation stresses an...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829801200304
更新日期：1998-01-01 00:00:00
abstract：:This study aims the in vivo biological characterization of an innovative minocycline delivery system, based on polymethylmethacrylate bone cement. Bone cements containing 1% or 2.5% (w/w) minocycline were formulated and evaluated through solid-state characterization. Biological evaluation was conducted in vivo, within...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328218795290
更新日期：2018-09-01 00:00:00
abstract：:The production of large quantities of functional vascularized bone tissue ex vivo still represent an unmet clinical challenge. Microcarriers offer a potential solution to scalable manufacture of bone tissue due to their high surface area-to-volume ratio and the capacity to be assembled using a modular approach. Microc...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328217720812
更新日期：2017-09-01 00:00:00
abstract：:The adhesion of platelets, red blood cells, and lymphocytes onto various polymer substrates, hydrophobic to hydrophilic in nature, has been studied. Cell adhesion is found to be higher on hydrophilic substrates. The stability of these adhered cells has also been studied under a flow rate of 20 ml/min. Further the effe...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829100600105
更新日期：1991-07-01 00:00:00
abstract：:Bioimaging at a subcellular resolution to label cytoplasm and nucleus in living cell by just one photoluminescent nanoparticle has great application potential in bioresearch, preclinical diagnosis, screening, and image-guided therapy of life-threatening diseases. Herein, we report a novel arginine (Arg) functionalized...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2017-10-01 00:00:00
abstract：:Phase-sensitive in situ gel-forming controlled release formulations of insulin were prepared using poly(lactide-co-glycolide) and a solvent system consisting of various proportions of benzyl benzoate and benzyl alcohol. The in vitro release samples of formulations were assayed for insulin content by enzyme linked immu...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
abstract：:Solvent-based methods are commonly employed for the production of polyester-based samples and coatings in both medical device production and research. The influence of solvent casting and subsequent drying time was studied using thermal analysis, spectroscopy and weight measurement for four grades of 50 : 50 poly(lact...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
abstract：:Carbon-fibre-reinforced polyether ether ketone (CFR-PEEK) exhibits excellent biomechanical properties as it has an elastic modulus similar to bone. However, CFR-PEEK displays inferior biocompatibility compared with titanium alloy and coating techniques are therefore of interest in order to improve integration. In this...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2014-08-01 00:00:00
abstract：:To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic fu...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2016-02-01 00:00:00
abstract：:Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532828700200305
更新日期：1988-01-01 00:00:00
abstract：:The purpose of this research was to develop novel nanoparticles (NPs) of star-like copolymer mannitol-functionalized poly(lactide)-vitamin E TPGS (M-PLA-TPGS) for paclitaxel delivery for prostate cancer treatment, and evaluate their therapeutic effects in prostate cancer cell line and animal model in comparison with t...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2014-09-01 00:00:00
abstract：:Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：2008-05-01 00:00:00
abstract：:Compounds of a silicone elastomer suitable for preparing maxillofacial prostheses, reinforced with various amounts of silica powder, have been studied for their mechanical response and wetting properties in terms of contact angle. Tensile strength and elongation at break showed an increase with increasing silica volum...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：1998-07-01 00:00:00
abstract：PURPOSE:To produce biodurable small diameter microporous vascular grafts with self-sealing properties for vascular access, for peripheral vascular and potentially for coronary artery bypass. The prosthesis should retain compliance and pulsatile flow in situ using a unique modus operandi permitting wall compression whic...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
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更新日期：1995-10-01 00:00:00
abstract：:Phenylalanine ethyl ester (PAE)-alginate (Alg) conjugate (PAE-Alg, PEA) was synthesized and formation of an amide bond between PAE and Alg was confirmed by Fourier transformed-infrared and (1)H nuclear magnetic resonance spectroscopy. The degree of PAE substitution was 3.5-4.7 (PAE group per hundred sugar residues of ...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328216630497
更新日期：2016-07-01 00:00:00
abstract：:Thrombosis is the most serious acute problem for small diameter arterial bypass grafts. In this research, small diameter expanded polytetrafluoroethylene (e-PTFE) vascular grafts were coated with acetylsalicylic acid (ASA) loaded poly (d,l-lactide) (PLA) by a solvent casting method. The feasibility and efficacy of thi...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/088532829400800404
更新日期：1994-04-01 00:00:00
abstract：:The aim of this study was to investigate the effect of C-Graft particles on formation of new cementum and bone in periodontal bone defects in dog. Healing and tissue change were histologically determined at 2, 4, 8, and 16 weeks. Little bone or cementum formation was observed in the control group. A statistically sign...
journal_title：Journal of biomaterials applications
pub_type： 杂志文章
doi：10.1177/0885328208094427
更新日期：2009-08-01 00:00:00
