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Whole brain and grey matter volume of Japanese patients with multiple sclerosis.

Abstract：

:We evaluated the brain volume and rate of atrophy in 85 Japanese patients with multiple sclerosis (MS). The mean brain volume was smaller and the rate of atrophy appeared to be more rapid in MS patients than in normal subjects. The brain atrophy seemed to exist from the early stage of MS and was prominent in the grey matter. Patients with progressive MS showed severer atrophy. We show the existence of pathological brain atrophy in Japanese MS patients for the first time, although the rate of atrophy may be much slower than in Caucasian patients.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Akaishi T,Nakashima I,Mugikura S,Aoki M,Fujihara K

doi

10.1016/j.jneuroim.2017.03.009

subject

Has Abstract

pub_date

2017-05-15 00:00:00

pages

68-75

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(17)30012-7

journal_volume

306

pub_type

杂志文章

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