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Differentiation of skeletal muscle from dissociated optic nerve cells. Immunocytochemical observations.

Abstract：

:Multinucleate striated contractile fibers which exhibit differentiation markers characteristic of skeletal muscle develop regularly in optic nerve cultured from 10-day-old rats. In identical conditions, muscle fibers arise also from pineal and occasionally from spinal cord, but not from meninges, cerebral blood vessels, trigeminal nerve, nor brachial plexus. These observations are consistent with the suggestion that mammalian cephalic neuroectoderm has myogenic potential. The concept that skeletal muscle in different anatomical regions might have different embryonic origins could be relevant to the distribution of muscles affected by certain diseases in man.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Wier ML,Lennon VA

doi

10.1016/0165-5728(81)90008-4

subject

Has Abstract

pub_date

1981-03-01 00:00:00

pages

61-8

issue

1

eissn

0165-5728

issn

1872-8421

pii

0165-5728(81)90008-4

journal_volume

1

pub_type

杂志文章

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