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Activated microglia do not form functional gap junctions in vivo.

Abstract：

:We investigated whether microglia form gap junctions with themselves, or with astrocytes, oligodendrocytes, or neurons in vivo in normal mouse brains, and in pathological conditions that induce microglial activation - brain injury and a model of Alzheimer's disease. Although microglia are in close physical proximity to glia and neurons, they do not form functional gap junctions under these pathological conditions.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Wasseff SK,Scherer SS

doi

10.1016/j.jneuroim.2014.02.005

subject

Has Abstract

pub_date

2014-04-15 00:00:00

pages

90-3

issue

1-2

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(14)00036-8

journal_volume

269

pub_type

杂志文章

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